TW200844110A - Diagnosis and treatment of alzheimer's disease and other neurodementing diseases - Google Patents

Diagnosis and treatment of alzheimer's disease and other neurodementing diseases Download PDF

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Publication number
TW200844110A
TW200844110A TW097101288A TW97101288A TW200844110A TW 200844110 A TW200844110 A TW 200844110A TW 097101288 A TW097101288 A TW 097101288A TW 97101288 A TW97101288 A TW 97101288A TW 200844110 A TW200844110 A TW 200844110A
Authority
TW
Taiwan
Prior art keywords
seq
amino acid
antibody
sequence
peptide
Prior art date
Application number
TW097101288A
Other languages
English (en)
Chinese (zh)
Inventor
Richard Dodel
Michael Bacher
Michael Przybylski
Raluca Stefanescu
Marilena Manea
Original Assignee
Univ Marburg Philipps
Univ Konstanz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP07000521A external-priority patent/EP1944315A1/en
Priority claimed from EP07000507A external-priority patent/EP1944314A1/en
Application filed by Univ Marburg Philipps, Univ Konstanz filed Critical Univ Marburg Philipps
Publication of TW200844110A publication Critical patent/TW200844110A/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
TW097101288A 2007-01-11 2008-01-11 Diagnosis and treatment of alzheimer's disease and other neurodementing diseases TW200844110A (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US88452607P 2007-01-11 2007-01-11
US88451307P 2007-01-11 2007-01-11
EP07000521A EP1944315A1 (en) 2007-01-11 2007-01-11 Prophylaxis and therapy of alzheimer's disease and other neurodementing diseases
EP07000507A EP1944314A1 (en) 2007-01-11 2007-01-11 Diagnosis of Alzheimer's disease and other neurodementing disorders
US98166707P 2007-10-22 2007-10-22
US98167507P 2007-10-22 2007-10-22
EP07119002 2007-10-22
EP07119026 2007-10-22

Publications (1)

Publication Number Publication Date
TW200844110A true TW200844110A (en) 2008-11-16

Family

ID=39609117

Family Applications (1)

Application Number Title Priority Date Filing Date
TW097101288A TW200844110A (en) 2007-01-11 2008-01-11 Diagnosis and treatment of alzheimer's disease and other neurodementing diseases

Country Status (11)

Country Link
US (3) US7939075B2 (enExample)
EP (1) EP2104682B1 (enExample)
JP (1) JP2010515717A (enExample)
AU (1) AU2008204335B2 (enExample)
CA (1) CA2675340C (enExample)
DK (1) DK2104682T3 (enExample)
ES (1) ES2610474T3 (enExample)
PL (1) PL2104682T3 (enExample)
SI (1) SI2104682T1 (enExample)
TW (1) TW200844110A (enExample)
WO (1) WO2008084402A2 (enExample)

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Also Published As

Publication number Publication date
SI2104682T1 (sl) 2017-05-31
US20120040382A1 (en) 2012-02-16
WO2008084402A3 (en) 2009-04-09
AU2008204335B2 (en) 2013-06-13
CA2675340C (en) 2018-07-31
EP2104682A2 (en) 2009-09-30
US7939075B2 (en) 2011-05-10
CA2675340A1 (en) 2008-07-17
EP2104682B1 (en) 2016-09-21
US20090028869A1 (en) 2009-01-29
JP2010515717A (ja) 2010-05-13
US20120039897A1 (en) 2012-02-16
AU2008204335A1 (en) 2008-07-17
PL2104682T3 (pl) 2017-03-31
WO2008084402A2 (en) 2008-07-17
ES2610474T3 (es) 2017-04-27
DK2104682T3 (en) 2017-01-16
WO2008084402A8 (en) 2009-08-27
US8491903B2 (en) 2013-07-23

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