JP2010515717A - アルツハイマーおよび他の神経性認知症疾患の診断ならびに処置 - Google Patents

アルツハイマーおよび他の神経性認知症疾患の診断ならびに処置 Download PDF

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JP2010515717A
JP2010515717A JP2009545252A JP2009545252A JP2010515717A JP 2010515717 A JP2010515717 A JP 2010515717A JP 2009545252 A JP2009545252 A JP 2009545252A JP 2009545252 A JP2009545252 A JP 2009545252A JP 2010515717 A JP2010515717 A JP 2010515717A
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seq
amino acid
sequence
antibody
disease
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JP2010515717A5 (enExample
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ドーデル・リヒャルト
バッハー・ミヒャエル
プルツィビュルスキ・ミヒャエル
ステファネスク・ラルカ
マネア・マリレナ
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フィリップス−ウニベルジテート・マールブルク
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Priority claimed from EP07000521A external-priority patent/EP1944315A1/en
Priority claimed from EP07000507A external-priority patent/EP1944314A1/en
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Publication of JP2010515717A publication Critical patent/JP2010515717A/ja
Publication of JP2010515717A5 publication Critical patent/JP2010515717A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2009545252A 2007-01-11 2008-01-11 アルツハイマーおよび他の神経性認知症疾患の診断ならびに処置 Pending JP2010515717A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US88451307P 2007-01-11 2007-01-11
US88452607P 2007-01-11 2007-01-11
EP07000521A EP1944315A1 (en) 2007-01-11 2007-01-11 Prophylaxis and therapy of alzheimer's disease and other neurodementing diseases
EP07000507A EP1944314A1 (en) 2007-01-11 2007-01-11 Diagnosis of Alzheimer's disease and other neurodementing disorders
US98166707P 2007-10-22 2007-10-22
US98167507P 2007-10-22 2007-10-22
EP07119002 2007-10-22
EP07119026 2007-10-22
PCT/IB2008/000456 WO2008084402A2 (en) 2007-01-11 2008-01-11 Diagnosis and treatment of alzheimer's and other neurodementing diseases

Publications (2)

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JP2010515717A true JP2010515717A (ja) 2010-05-13
JP2010515717A5 JP2010515717A5 (enExample) 2011-03-31

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JP2009545252A Pending JP2010515717A (ja) 2007-01-11 2008-01-11 アルツハイマーおよび他の神経性認知症疾患の診断ならびに処置

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US (3) US7939075B2 (enExample)
EP (1) EP2104682B1 (enExample)
JP (1) JP2010515717A (enExample)
AU (1) AU2008204335B2 (enExample)
CA (1) CA2675340C (enExample)
DK (1) DK2104682T3 (enExample)
ES (1) ES2610474T3 (enExample)
PL (1) PL2104682T3 (enExample)
SI (1) SI2104682T1 (enExample)
TW (1) TW200844110A (enExample)
WO (1) WO2008084402A2 (enExample)

Cited By (3)

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JP2013083644A (ja) * 2011-10-07 2013-05-09 Korea Center For Disease Control And Prevention 血液内アミロイドβ抗体に特異的に結合する新規なＡβ２２（ｐＥ）−４２ペプチドを有効成分として含む痴呆症診断用キット
JP2014529087A (ja) * 2011-10-04 2014-10-30 アフィリス・アクチェンゲゼルシャフトＡｆｆｉｒｉｓ Ａｇ アルツハイマー病の診断方法
WO2015111430A1 (ja) * 2014-01-21 2015-07-30 株式会社 島津製作所 Ａｐｐ切断型ペプチドの測定方法

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JP7368856B2 (ja) 2017-07-25 2023-10-25 トゥルーバインディング，インコーポレイテッド Ｔｉｍ－３とそのリガンドとの相互作用の遮断によるがん治療
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JP2023528797A (ja) 2020-05-26 2023-07-06 トゥルーバインディング，インコーポレイテッド ガレクチン－３を遮断することにより炎症性疾患を処置する方法
JP2023549854A (ja) 2020-11-16 2023-11-29 スロゼン オペレーティング， インコーポレイテッド 肝臓特異的Ｗｎｔシグナル増強分子およびその使用
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JP2014529087A (ja) * 2011-10-04 2014-10-30 アフィリス・アクチェンゲゼルシャフトＡｆｆｉｒｉｓ Ａｇ アルツハイマー病の診断方法
JP2013083644A (ja) * 2011-10-07 2013-05-09 Korea Center For Disease Control And Prevention 血液内アミロイドβ抗体に特異的に結合する新規なＡβ２２（ｐＥ）−４２ペプチドを有効成分として含む痴呆症診断用キット
WO2015111430A1 (ja) * 2014-01-21 2015-07-30 株式会社 島津製作所 Ａｐｐ切断型ペプチドの測定方法
US10942190B2 (en) 2014-01-21 2021-03-09 Shimadzu Corporation Measurement method for amyloid precursor protein cleavage peptides

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AU2008204335B2 (en) 2013-06-13
TW200844110A (en) 2008-11-16
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EP2104682B1 (en) 2016-09-21
AU2008204335A1 (en) 2008-07-17
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CA2675340C (en) 2018-07-31
ES2610474T3 (es) 2017-04-27
US20090028869A1 (en) 2009-01-29
DK2104682T3 (en) 2017-01-16
US20120040382A1 (en) 2012-02-16
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US8491903B2 (en) 2013-07-23
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