TW200518771A - Formulations for coated microprojections containing non-volatile counterions - Google Patents
Formulations for coated microprojections containing non-volatile counterionsInfo
- Publication number
- TW200518771A TW200518771A TW093119156A TW93119156A TW200518771A TW 200518771 A TW200518771 A TW 200518771A TW 093119156 A TW093119156 A TW 093119156A TW 93119156 A TW93119156 A TW 93119156A TW 200518771 A TW200518771 A TW 200518771A
- Authority
- TW
- Taiwan
- Prior art keywords
- formulations
- containing non
- coated microprojections
- counterions
- volatile counterions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Virology (AREA)
- Emergency Medicine (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48402003P | 2003-06-30 | 2003-06-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200518771A true TW200518771A (en) | 2005-06-16 |
Family
ID=34062010
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW093119156A TW200518771A (en) | 2003-06-30 | 2004-06-29 | Formulations for coated microprojections containing non-volatile counterions |
Country Status (13)
Country | Link |
---|---|
US (2) | US7579013B2 (zh) |
EP (1) | EP1638523B8 (zh) |
JP (1) | JP5456234B2 (zh) |
KR (1) | KR20060038407A (zh) |
CN (1) | CN1842320B (zh) |
AR (1) | AR044964A1 (zh) |
AU (1) | AU2004255218A1 (zh) |
BR (1) | BRPI0412029A (zh) |
CA (1) | CA2530531A1 (zh) |
ES (1) | ES2437565T3 (zh) |
MX (1) | MXPA06000281A (zh) |
TW (1) | TW200518771A (zh) |
WO (1) | WO2005004842A2 (zh) |
Families Citing this family (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6918901B1 (en) * | 1997-12-10 | 2005-07-19 | Felix Theeuwes | Device and method for enhancing transdermal agent flux |
US7419481B2 (en) * | 2000-10-13 | 2008-09-02 | Alza Corporation | Apparatus and method for piercing skin with microprotrusions |
RU2275871C2 (ru) * | 2000-10-13 | 2006-05-10 | Алза Корпорейшн | Устройство и способ для прокалывания кожи микровыступами |
MXPA03003303A (es) * | 2000-10-13 | 2004-12-13 | Johnson & Johnson | Retenedor del miembro de microprotrusion para aplicador de impacto. |
EP2085109A3 (en) * | 2000-10-26 | 2009-09-02 | Alza Corporation | Transdermal drug delivery devices having coated microprotrusions |
US6855372B2 (en) * | 2001-03-16 | 2005-02-15 | Alza Corporation | Method and apparatus for coating skin piercing microprojections |
US20020193729A1 (en) * | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
US20050123507A1 (en) | 2003-06-30 | 2005-06-09 | Mahmoud Ameri | Formulations for coated microprojections having controlled solubility |
AU2004255228A1 (en) * | 2003-06-30 | 2005-01-20 | Alza Corporation | Method for coating skin piercing microprojections |
EP1638523B8 (en) * | 2003-06-30 | 2013-12-25 | ALZA Corporation | Formulations for coated microprojections containing non-volatile counterions |
PE20050288A1 (es) * | 2003-07-02 | 2005-04-29 | Alza Corp | Metodo y parche de inmunizacion por disposicion de microproyeccion |
CA2534823A1 (en) * | 2003-08-04 | 2005-02-24 | Alza Corporation | Method and device for enhancing transdermal agent flux |
US8524272B2 (en) | 2003-08-15 | 2013-09-03 | Mylan Technologies, Inc. | Transdermal patch incorporating active agent migration barrier layer |
WO2005020912A2 (en) | 2003-08-25 | 2005-03-10 | 3M Innovative Properties Company | Delivery of immune response modifier compounds |
JP2007519613A (ja) * | 2003-10-23 | 2007-07-19 | アルザ・コーポレーシヨン | 微小突出部をコーティングするための安定化されたdnaの組成物 |
KR20060108682A (ko) * | 2003-10-24 | 2006-10-18 | 알자 코포레이션 | 경피 약물 전달을 증대시키기 위한 전처리 방법 및 장치 |
AU2004287412A1 (en) * | 2003-10-28 | 2005-05-19 | Alza Corporation | Method and apparatus for reducing the incidence of tobacco use |
CN100571643C (zh) | 2003-10-31 | 2009-12-23 | 阿尔扎公司 | 用于微凸起阵列的自驱动施加器 |
AU2004292954A1 (en) * | 2003-11-13 | 2005-06-09 | Alza Corporation | Composition and apparatus for transdermal delivery |
KR20070011481A (ko) * | 2004-04-13 | 2007-01-24 | 알자 코포레이션 | 다중 백신의 경피 전달용 기구 및 방법 |
AU2005244734A1 (en) * | 2004-05-13 | 2005-12-01 | Alza Corporation | Apparatus and method for transdermal delivery of parathyroid hormone agents |
US20060034903A1 (en) * | 2004-08-11 | 2006-02-16 | Yuh-Fun Maa | Apparatus and method for transdermal delivery of natriuretic peptides |
JP2008528509A (ja) * | 2005-01-21 | 2008-07-31 | アルザ コーポレイション | 少なくとも1つの対イオンを含む、向上した安定性でマイクロニードルをコーティングするための治療用ペプチド製剤 |
US7488316B2 (en) * | 2005-01-25 | 2009-02-10 | Microchips, Inc. | Control of drug release by transient modification of local microenvironments |
EP1853231A2 (en) * | 2005-02-16 | 2007-11-14 | Alza Corporation | Apparatus and method for transdermal delivery of erythropoetin-based agents |
JP5438872B2 (ja) * | 2005-06-02 | 2014-03-12 | アルザ コーポレイション | 経皮的送達デバイスの最終滅菌法 |
AU2006252377A1 (en) * | 2005-06-02 | 2006-12-07 | Alza Corporation | Method for terminal sterilization of transdermal delivery devices |
WO2007033015A1 (en) * | 2005-09-12 | 2007-03-22 | Alza Corporation | Coatable transdermal delivery microprojection assembly |
EP1948139A4 (en) * | 2005-11-18 | 2012-04-04 | 3M Innovative Properties Co | COATING COMPOSITIONS, COATINGS DERIVED THEREFROM, AND MICRO-NETWORKS COMPRISING SUCH COATINGS |
US8554317B2 (en) * | 2005-11-30 | 2013-10-08 | 3M Innovative Properties Company | Microneedle arrays and methods of use thereof |
JP2009522288A (ja) * | 2005-12-28 | 2009-06-11 | アルザ コーポレイション | 安定な治療剤形 |
CA2680690A1 (en) * | 2006-03-15 | 2007-09-20 | Alza Corporation | Apparatus and method for transdermal delivery of parathyroid hormone agents to prevent or treat osteopenia |
US20070293816A1 (en) * | 2006-04-25 | 2007-12-20 | Alza Corporation | Microprojection Array Application with Grouped Microprojections for High Drug Loading |
WO2007127815A2 (en) * | 2006-04-25 | 2007-11-08 | Alza Corporation | Microprojection array application with multilayered microprojection member for high drug loading |
US7771542B1 (en) | 2006-05-30 | 2010-08-10 | Stone Chemical Company | Compositions and methods for removing lead from metal surfaces |
KR20140001257A (ko) | 2008-05-13 | 2014-01-06 | 유니버시티 오브 캔사스 | 금속 추출 펩타이드(map) 태그 및 관련된 방법 |
LT2568806T (lt) | 2010-05-12 | 2016-09-26 | Radius Health, Inc. | Terapiniai režimai |
US9693950B2 (en) | 2010-05-28 | 2017-07-04 | 3M Innovative Properties Company | Aqueous formulations for coating microneedle arrays |
JP5965909B2 (ja) | 2010-09-28 | 2016-08-10 | ラジウス ヘルス,インコーポレイテッド | 選択的アンドロゲン受容体モジュレーター |
AU2011332815A1 (en) * | 2010-11-23 | 2013-05-30 | Presage Biosciences, Inc. | Therapeutic methods and compositions for solid delivery |
CN102090904B (zh) * | 2011-02-17 | 2013-04-03 | 中国中医科学院中医临床基础医学研究所 | 中药注射剂快速过敏皮试检测仪 |
US8512679B2 (en) | 2011-03-04 | 2013-08-20 | Elwha Llc | Glassy compositions |
NL2007382C2 (en) * | 2011-09-09 | 2013-03-12 | Univ Leiden | Method to coat an active agent to a surface. |
JP2014534864A (ja) | 2011-10-28 | 2014-12-25 | プレサージュ バイオサイエンシズ,インコーポレイテッド | 薬物デリバリー方法 |
CA2857502C (en) | 2011-11-30 | 2019-08-13 | 3M Innovative Properties Company | Microneedle device including a peptide therapeutic agent and an amino acid and methods of making and using the same |
WO2013181461A2 (en) | 2012-06-01 | 2013-12-05 | University Of Kansas | Metal abstraction peptide with superoxide dismutase activity |
US10980865B2 (en) | 2012-08-10 | 2021-04-20 | Aquavit Pharmaceuticals, Inc. | Direct application system and method for the delivery of bioactive compositions and formulations |
JP6175485B2 (ja) | 2013-02-13 | 2017-08-02 | 久光製薬株式会社 | マイクロニードルコーティング用組成物及びマイクロニードルデバイス |
JP6246784B2 (ja) | 2013-02-13 | 2017-12-13 | 久光製薬株式会社 | マイクロニードルコーティング用組成物及びマイクロニードルデバイス |
US9782344B2 (en) * | 2013-08-22 | 2017-10-10 | Zp Opco, Inc. | Stable glucagon peptide formulations |
ES2708996T3 (es) * | 2013-08-22 | 2019-04-12 | Zp Opco Inc | Formulaciones estables de péptido glucagón |
EP3250228A1 (en) | 2015-01-27 | 2017-12-06 | 3M Innovative Properties Company | Alum-containing coating formulations for microneedle vaccine patches |
US9744239B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9750785B2 (en) | 2015-01-30 | 2017-09-05 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9925233B2 (en) | 2015-01-30 | 2018-03-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9744209B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9937223B2 (en) | 2015-01-30 | 2018-04-10 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9687526B2 (en) | 2015-01-30 | 2017-06-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
IL310069A (en) | 2015-04-29 | 2024-03-01 | Radius Pharmaceuticals Inc | Cancer treatment methods |
CN108135837B (zh) * | 2015-10-09 | 2022-05-31 | 3M创新有限公司 | 用于涂布微针阵列的锌组合物 |
EP3416618A1 (en) | 2016-02-19 | 2018-12-26 | ZP Opco, Inc. | Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines |
EP3998061A1 (en) * | 2016-04-18 | 2022-05-18 | Radius Health, Inc. | Formulations of abaloparatide, transdermal patches thereof, and uses thereof |
KR102397890B1 (ko) | 2016-06-22 | 2022-05-12 | 일립시스 파마 리미티드 | Ar+ 유방암 치료 방법 |
AR109621A1 (es) * | 2016-10-24 | 2018-12-26 | Janssen Pharmaceuticals Inc | Formulaciones de vacunas contra glucoconjugados de expec |
WO2018129419A1 (en) | 2017-01-05 | 2018-07-12 | Radius Pharmaceuticals, Inc. | Polymorphic forms of rad1901-2hcl |
US11660264B2 (en) | 2017-08-23 | 2023-05-30 | Emergex USA Corporation | Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches |
SG10201800072YA (en) * | 2018-01-03 | 2019-08-27 | Micropoint Tech Pte Ltd | Microneedle Patches Comprising Corticosteroid |
US11660265B2 (en) | 2018-06-28 | 2023-05-30 | Emergex USA Corporation | Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches |
CN108721598B (zh) * | 2018-07-03 | 2020-06-05 | 北京市新里程医药科技有限公司 | 一种缩宫素原料的制备方法及其药物组合物和制剂 |
SG11202013177WA (en) | 2018-07-04 | 2021-01-28 | Radius Pharmaceuticals Inc | Polymorphic forms of rad 1901-2hcl |
Family Cites Families (100)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE25637E (en) | 1964-09-08 | Means for vaccinating | ||
US3123212A (en) | 1964-03-03 | Multiple disposable intracutaneous injector package | ||
GB179994A (en) | 1921-02-02 | 1922-05-02 | Achilee Macchioni | Throttling of the exhaust in a two-stroke cycle internal combustion motor applied to a locomotive for the purpose of increasing the power of the said motor |
US2619962A (en) | 1948-02-19 | 1952-12-02 | Res Foundation | Vaccination appliance |
US2893392A (en) | 1958-01-08 | 1959-07-07 | American Cyanamid Co | Article of manufacture for intracutaneous injections |
US3072122A (en) | 1959-01-15 | 1963-01-08 | Rosenthal Sol Roy | Package for transcutaneous injection |
US3136314A (en) | 1960-08-01 | 1964-06-09 | Kravitz Harvey | Vaccinating devices |
US3221739A (en) | 1962-03-26 | 1965-12-07 | Rosenthal Sol Roy | Injection device |
US3221740A (en) | 1962-08-31 | 1965-12-07 | Rosenthal Sol Roy | Injection device |
US3964482A (en) | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
US3678150A (en) | 1971-07-27 | 1972-07-18 | American Cyanamid Co | Process for improving the stability of ppd, qt and histoplasmin on tine applicators |
BE795384A (fr) | 1972-02-14 | 1973-08-13 | Ici Ltd | Pansements |
OA05448A (fr) | 1975-10-16 | 1981-03-31 | Manufrance Manufacture Francai | Dispositif vaccinateur multipénétrant. |
FR2474856A1 (fr) | 1980-01-31 | 1981-08-07 | Merieux Inst | Dispositif scarificateur |
SE8501990D0 (sv) | 1985-04-24 | 1985-04-24 | Pharmacia Ab | Beleggningsforfarande |
KR970008118B1 (ko) | 1987-07-09 | 1997-05-21 | 엘테에스 로오만 테라피-지스테메 게엠베하 운트 콤파니 카게 | 피부 침투성 치료 시스템 |
US5051132A (en) * | 1989-06-15 | 1991-09-24 | Nippon Kayaku Kabushiki Kaisha | Lyophilized preparation of 6-(3-dimethylaminopropionyl)forskolin |
CA2016900A1 (en) | 1989-07-06 | 1991-01-06 | Ronald J. Filipski | Tines structure in clinical applicator |
EP0429842B1 (en) | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
JPH04134033A (ja) * | 1990-01-19 | 1992-05-07 | Nippon Kayaku Co Ltd | エトポシド−2−ジメチルアミノ体の凍結乾燥製剤 |
US5279544A (en) | 1990-12-13 | 1994-01-18 | Sil Medics Ltd. | Transdermal or interdermal drug delivery devices |
DE4242919A1 (de) * | 1992-12-18 | 1994-06-23 | Boehringer Mannheim Gmbh | Verfahren zur Herstellung von lagerstabilen wässrigen pharmazeutischen Zubereitungen von G-CSF |
DE4341444C2 (de) | 1993-12-04 | 1996-03-14 | Lohmann Therapie Syst Lts | Wirkstoffhaltiges Pflaster und Verfahren zu seiner Herstellung |
US5496801A (en) * | 1993-12-23 | 1996-03-05 | Allelix Biopharmaceuticals Inc. | Parathyroid hormone formulation |
US5487726A (en) | 1994-06-16 | 1996-01-30 | Ryder International Corporation | Vaccine applicator system |
EP1138319A3 (en) | 1994-08-04 | 2003-03-19 | Elan Drug Delivery Limited | Solid delivery systems for controlled release of molecules incorporated therein and methods of making same |
US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
AU3758595A (en) | 1994-09-30 | 1996-04-26 | Rutgers, The State University | Direct introduction of foreign materials into cells |
CA2205444A1 (en) | 1994-12-09 | 1996-06-13 | Novartis Ag | Transdermal system |
US5866536A (en) * | 1995-03-31 | 1999-02-02 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
WO1996037256A1 (en) | 1995-05-22 | 1996-11-28 | Silicon Microdevices, Inc. | Micromechanical patch for enhancing the delivery of compounds through the skin |
AU5740496A (en) | 1995-05-22 | 1996-12-11 | General Hospital Corporation, The | Micromechanical device and method for enhancing delivery of compounds through the skin |
DE19525607A1 (de) | 1995-07-14 | 1997-01-16 | Boehringer Ingelheim Kg | Transcorneales Arzneimittelfreigabesystem |
AR008242A1 (es) | 1996-06-18 | 1999-12-29 | Alza Corp | Dispositivo para atravesar el estrato corneo de una superficie corporal |
US6183434B1 (en) | 1996-07-03 | 2001-02-06 | Spectrx, Inc. | Multiple mechanical microporation of skin or mucosa |
US5916524A (en) | 1997-07-23 | 1999-06-29 | Bio-Dot, Inc. | Dispensing apparatus having improved dynamic range |
US5741554A (en) | 1996-07-26 | 1998-04-21 | Bio Dot, Inc. | Method of dispensing a liquid reagent |
US5738728A (en) | 1996-07-26 | 1998-04-14 | Bio Dot, Inc. | Precision metered aerosol dispensing apparatus |
US5743960A (en) | 1996-07-26 | 1998-04-28 | Bio-Dot, Inc. | Precision metered solenoid valve dispenser |
DE69718495T2 (de) | 1996-09-17 | 2003-11-20 | Deka Products Lp | System zur medikamentenabgabe durch transport |
AU722574B2 (en) | 1996-12-20 | 2000-08-10 | Alza Corporation | Device and method for enhancing transdermal agent flux |
DE19654391A1 (de) | 1996-12-27 | 1998-07-02 | Basf Ag | Katalysator zur selektiven Herstellung von Propylen aus Propan |
ID21673A (id) | 1996-12-31 | 1999-07-08 | Shell Internationale Res Maatc | Anjungan tiang dengan alur vertikal |
US6918901B1 (en) | 1997-12-10 | 2005-07-19 | Felix Theeuwes | Device and method for enhancing transdermal agent flux |
KR100572539B1 (ko) | 1997-12-11 | 2006-04-24 | 알자 코포레이션 | 경피성 작용제 유동률을 증진시키기 위한 장치 |
CN1206004C (zh) | 1997-12-11 | 2005-06-15 | 阿尔扎有限公司 | 增强透皮物剂流量的装置 |
CN1170603C (zh) | 1997-12-11 | 2004-10-13 | 阿尔扎有限公司 | 增强透皮物剂流量的装置 |
EP1051155B1 (en) | 1998-01-30 | 2002-06-26 | Novartis Consumer Health S.A. | Nasal solutions |
US6091975A (en) | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
JP2002517300A (ja) | 1998-06-10 | 2002-06-18 | ジョージア テック リサーチ コーポレイション | 微小針デバイスおよび製造方法ならびにそれらの使用 |
DE69921489T2 (de) | 1998-08-31 | 2005-10-27 | Johnson & Johnson Consumer Companies, Inc. | Elektrotransportvorrichtung mit klingen |
JP3722268B2 (ja) | 1998-09-03 | 2005-11-30 | 栗田工業株式会社 | 抗菌性組成物 |
SE9803517D0 (sv) * | 1998-10-15 | 1998-10-15 | Astra Ab | Pharmaceutical preparation |
AR022119A1 (es) * | 1998-12-22 | 2002-09-04 | Bausch & Lomb | Composiciones que contienen feniramina y metodo para el tratamiento de las respuestas alergicas |
GB9901253D0 (en) * | 1999-01-20 | 1999-03-10 | Isis Innovation | Bis-terpyridine-platinum(II) complexes |
US6884427B1 (en) | 1999-02-08 | 2005-04-26 | Aderans Research Institute, Inc. | Filamentary means for introducing agents into tissue of a living host |
US6743211B1 (en) | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
US6256533B1 (en) | 1999-06-09 | 2001-07-03 | The Procter & Gamble Company | Apparatus and method for using an intracutaneous microneedle array |
US6379324B1 (en) | 1999-06-09 | 2002-04-30 | The Procter & Gamble Company | Intracutaneous microneedle array apparatus |
GB9916316D0 (en) * | 1999-07-12 | 1999-09-15 | Quadrant Holdings Cambridge | Dry powder compositions |
US6623457B1 (en) | 1999-09-22 | 2003-09-23 | Becton, Dickinson And Company | Method and apparatus for the transdermal administration of a substance |
US6835184B1 (en) | 1999-09-24 | 2004-12-28 | Becton, Dickinson And Company | Method and device for abrading skin |
US20020095134A1 (en) | 1999-10-14 | 2002-07-18 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
DK1239916T3 (da) * | 1999-12-10 | 2006-04-03 | Alza Corp | Indretning og fremgangsmåde til at forbedre perforering af hud med mikrofremspring |
CH694730A5 (de) * | 2000-02-09 | 2005-06-30 | Sumitomo Chemical Co | Verfahren zum Herstellen optisch aktiver Hemiester. |
CA2380423A1 (en) * | 2000-05-17 | 2001-11-22 | Bionebraska, Inc. | Peptide pharmaceutical formulations |
AU2001258755A1 (en) | 2000-05-17 | 2001-11-26 | Senju Pharmaceutical Co. Ltd. | Ophthalmic solution |
US6565532B1 (en) | 2000-07-12 | 2003-05-20 | The Procter & Gamble Company | Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup |
US6537242B1 (en) | 2000-06-06 | 2003-03-25 | Becton, Dickinson And Company | Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance |
US6589202B1 (en) | 2000-06-29 | 2003-07-08 | Becton Dickinson And Company | Method and apparatus for transdermally sampling or administering a substance to a patient |
GB0016002D0 (en) * | 2000-06-29 | 2000-08-23 | Glaxo Group Ltd | Novel process for preparing crystalline particles |
US20050008683A1 (en) | 2000-06-29 | 2005-01-13 | Becton Dickinson And Company | Method for delivering interferons to the intradermal compartment |
US6440096B1 (en) | 2000-07-14 | 2002-08-27 | Becton, Dickinson And Co. | Microdevice and method of manufacturing a microdevice |
GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
BR0113749A (pt) * | 2000-09-08 | 2004-06-22 | Alza Corp | Métodos para inibir a diminuição no fluxo de droga transdérmica por inibição do fechamento das vias |
DE60111771T2 (de) | 2000-10-13 | 2006-05-04 | Alza Corp., Mountain View | Mikroklingeanordungsaufprallapplikator |
MXPA03003303A (es) | 2000-10-13 | 2004-12-13 | Johnson & Johnson | Retenedor del miembro de microprotrusion para aplicador de impacto. |
RU2275871C2 (ru) | 2000-10-13 | 2006-05-10 | Алза Корпорейшн | Устройство и способ для прокалывания кожи микровыступами |
EP2085109A3 (en) * | 2000-10-26 | 2009-09-02 | Alza Corporation | Transdermal drug delivery devices having coated microprotrusions |
WO2002064193A2 (en) | 2000-12-14 | 2002-08-22 | Georgia Tech Research Corporation | Microneedle devices and production thereof |
US6855372B2 (en) | 2001-03-16 | 2005-02-15 | Alza Corporation | Method and apparatus for coating skin piercing microprojections |
US7963935B2 (en) | 2001-04-20 | 2011-06-21 | Alza Corporation | Microprojection array having a beneficial agent containing coating |
US20020193729A1 (en) | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
US6881203B2 (en) | 2001-09-05 | 2005-04-19 | 3M Innovative Properties Company | Microneedle arrays and methods of manufacturing the same |
EP1469903A2 (en) | 2001-09-28 | 2004-10-27 | BioValve Technologies, Inc. | Microneedle with membrane |
US6689100B2 (en) | 2001-10-05 | 2004-02-10 | Becton, Dickinson And Company | Microdevice and method of delivering or withdrawing a substance through the skin of an animal |
EP1439870B1 (en) * | 2001-10-29 | 2009-01-14 | Becton, Dickinson and Company | Device for the delivery of a substance |
US20030199810A1 (en) | 2001-11-30 | 2003-10-23 | Trautman Joseph Creagan | Methods and apparatuses for forming microprojection arrays |
WO2003053258A1 (en) | 2001-12-20 | 2003-07-03 | Alza Corporation | Skin-piercing microprojections having piercing depth control |
US7015262B2 (en) | 2002-05-01 | 2006-03-21 | Lifescan, Inc. | Hydrophilic coatings for medical implements |
JP2006500974A (ja) | 2002-06-28 | 2006-01-12 | アルザ・コーポレーシヨン | 被覆され微細突起物を有する経皮的薬物送達装置 |
AR042815A1 (es) * | 2002-12-26 | 2005-07-06 | Alza Corp | Dispositivo de suministro de agente activo que tiene miembros compuestos |
US20050123507A1 (en) | 2003-06-30 | 2005-06-09 | Mahmoud Ameri | Formulations for coated microprojections having controlled solubility |
EP1638523B8 (en) * | 2003-06-30 | 2013-12-25 | ALZA Corporation | Formulations for coated microprojections containing non-volatile counterions |
AU2004255228A1 (en) * | 2003-06-30 | 2005-01-20 | Alza Corporation | Method for coating skin piercing microprojections |
PE20050288A1 (es) * | 2003-07-02 | 2005-04-29 | Alza Corp | Metodo y parche de inmunizacion por disposicion de microproyeccion |
CN100571643C (zh) | 2003-10-31 | 2009-12-23 | 阿尔扎公司 | 用于微凸起阵列的自驱动施加器 |
AU2004292954A1 (en) | 2003-11-13 | 2005-06-09 | Alza Corporation | Composition and apparatus for transdermal delivery |
JP2008528509A (ja) * | 2005-01-21 | 2008-07-31 | アルザ コーポレイション | 少なくとも1つの対イオンを含む、向上した安定性でマイクロニードルをコーティングするための治療用ペプチド製剤 |
US9960402B2 (en) | 2016-09-07 | 2018-05-01 | Thunder Power New Energy Vehicle Development Company Limited | Process of manufacturing a battery system assembly using the battery system assembly press |
-
2004
- 2004-06-29 EP EP04756422.4A patent/EP1638523B8/en not_active Expired - Lifetime
- 2004-06-29 KR KR1020057025323A patent/KR20060038407A/ko not_active Application Discontinuation
- 2004-06-29 ES ES04756422.4T patent/ES2437565T3/es not_active Expired - Lifetime
- 2004-06-29 US US10/880,702 patent/US7579013B2/en not_active Expired - Lifetime
- 2004-06-29 JP JP2006518731A patent/JP5456234B2/ja not_active Expired - Fee Related
- 2004-06-29 CA CA002530531A patent/CA2530531A1/en not_active Abandoned
- 2004-06-29 CN CN2004800243347A patent/CN1842320B/zh not_active Expired - Fee Related
- 2004-06-29 WO PCT/US2004/021004 patent/WO2005004842A2/en active Application Filing
- 2004-06-29 MX MXPA06000281A patent/MXPA06000281A/es unknown
- 2004-06-29 BR BRPI0412029-9A patent/BRPI0412029A/pt not_active IP Right Cessation
- 2004-06-29 TW TW093119156A patent/TW200518771A/zh unknown
- 2004-06-29 AU AU2004255218A patent/AU2004255218A1/en not_active Abandoned
- 2004-06-30 AR ARP040102300A patent/AR044964A1/es not_active Application Discontinuation
-
2009
- 2009-08-24 US US12/583,761 patent/US8920817B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
KR20060038407A (ko) | 2006-05-03 |
US20040265354A1 (en) | 2004-12-30 |
US20100221305A1 (en) | 2010-09-02 |
WO2005004842A3 (en) | 2005-04-21 |
US8920817B2 (en) | 2014-12-30 |
EP1638523B1 (en) | 2013-10-30 |
CA2530531A1 (en) | 2005-01-20 |
JP5456234B2 (ja) | 2014-03-26 |
BRPI0412029A (pt) | 2006-09-05 |
WO2005004842A2 (en) | 2005-01-20 |
MXPA06000281A (es) | 2006-07-03 |
AU2004255218A1 (en) | 2005-01-20 |
EP1638523B8 (en) | 2013-12-25 |
ES2437565T3 (es) | 2014-01-13 |
EP1638523A2 (en) | 2006-03-29 |
AR044964A1 (es) | 2005-10-12 |
JP2007527392A (ja) | 2007-09-27 |
CN1842320B (zh) | 2013-06-19 |
CN1842320A (zh) | 2006-10-04 |
US7579013B2 (en) | 2009-08-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TW200518771A (en) | Formulations for coated microprojections containing non-volatile counterions | |
TW200635620A (en) | Formulations for coated microprojections having controlled solubility | |
MXPA03006774A (es) | Composiciones de recubrimiento para modificacion de superficies. | |
EP1601732A4 (en) | HARDENABLE COATING COMPOSITION | |
UA86413C2 (ru) | Сахарное покрытие и твердая дозированая форма, которая его содержит | |
DK1499667T3 (da) | Overtrækssammensætning til multiple hydrofile anvendelser | |
SG162804A1 (en) | Pyrazole based lxr modulators | |
PL1498461T3 (pl) | Kompozycje powlekające, zawierające rozpuszczalniki | |
WO2006058731A3 (de) | Strahlungshärtbare beschichtungsmassen | |
IS2799B (is) | Kladribínefnablöndur til inngjafar um munn | |
AU2003302035A1 (en) | Formulations used for the treatment of substrate surfaces | |
ITRM20040015A1 (it) | Procedimento per la composizione di un rivestimento nanocomposito. | |
GB0324355D0 (en) | Energy-curable coating compositions | |
AU2003221172A1 (en) | Water-based coating composition | |
MXPA04003755A (es) | Endoprotesis vasculares. | |
GB0215154D0 (en) | Coating compositions | |
GB0308895D0 (en) | Coating compositions | |
SG106113A1 (en) | Coating compositions | |
GB2384781B (en) | Coating compositions | |
GB2409861B (en) | Coating compositions | |
AU2003901311A0 (en) | Coating compositions | |
GB0319781D0 (en) | Coating compositions | |
WO2008058885A3 (de) | Strahlungshärtbare beschichtungsmassen | |
GB0321866D0 (en) | Coating compositions | |
AU2003291258A8 (en) | Coating compositions for use on substrates |