TW198710B - - Google Patents

Info

Publication number
TW198710B
TW198710B TW080106352A TW80106352A TW198710B TW 198710 B TW198710 B TW 198710B TW 080106352 A TW080106352 A TW 080106352A TW 80106352 A TW80106352 A TW 80106352A TW 198710 B TW198710 B TW 198710B
Authority
TW
Taiwan
Prior art keywords
novel
certain
defined hereinafter
formula
biphenylcarbonitriles
Prior art date
Application number
TW080106352A
Other languages
English (en)
Chinese (zh)
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10680408&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW198710(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ici Plc filed Critical Ici Plc
Application granted granted Critical
Publication of TW198710B publication Critical patent/TW198710B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/50—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Glass Compositions (AREA)
  • Turning (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Air Bags (AREA)
  • Electrotherapy Devices (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
TW080106352A 1990-08-09 1991-08-12 TW198710B (show.php)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909017482A GB9017482D0 (en) 1990-08-09 1990-08-09 Manufacturing process
GB919115244A GB9115244D0 (en) 1990-08-09 1991-07-16 Manufacturing process

Publications (1)

Publication Number Publication Date
TW198710B true TW198710B (show.php) 1993-01-21

Family

ID=10680408

Family Applications (1)

Application Number Title Priority Date Filing Date
TW080106352A TW198710B (show.php) 1990-08-09 1991-08-12

Country Status (23)

Country Link
EP (1) EP0470795B2 (show.php)
JP (1) JP3001298B2 (show.php)
KR (1) KR920004337A (show.php)
CN (1) CN1059516A (show.php)
AT (1) ATE117672T1 (show.php)
AU (1) AU646473B2 (show.php)
CA (1) CA2047369A1 (show.php)
CS (1) CS241391A3 (show.php)
DE (1) DE69106977T3 (show.php)
ES (1) ES2067159T3 (show.php)
FI (1) FI913640A7 (show.php)
GB (2) GB9017482D0 (show.php)
HU (1) HU207841B (show.php)
IL (1) IL98862A0 (show.php)
NO (1) NO174502B (show.php)
NZ (1) NZ239026A (show.php)
PL (1) PL291370A1 (show.php)
PT (1) PT98608A (show.php)
RU (1) RU2026285C1 (show.php)
TW (1) TW198710B (show.php)
YU (1) YU137891A (show.php)
ZA (1) ZA915566B (show.php)
ZW (1) ZW9591A1 (show.php)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP161A (en) * 1989-08-11 1991-12-20 Ici Plc Novel Quinoline derivatives.
DE4132632A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Substituierte imidazolyl-propensaeurederivate
DE4132633A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Cyclisch substituierte imidazolyl-propensaeurederivate
DE4132631A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Imidazolyl-propensaeurederivate
US5206374A (en) * 1991-11-18 1993-04-27 E. I. Du Pont De Nemours And Company Process for preparing tetrazolylphenylboronic acid intermediates
US5310928A (en) * 1991-11-18 1994-05-10 E. I. Du Pont De Nemours And Company Process for preparing biphenyltetrazole compounds
FR2688507B1 (fr) * 1992-03-16 1994-05-06 Synthelabo Derives de l'acide tetrazolylbenzeneboronique, leur preparation et leur utilisation comme intermediaires de synthese.
FR2689887B1 (fr) * 1992-04-13 1995-06-23 Sanofi Elf Procede de preparation d'un derive de biphenyle.
FR2696746B1 (fr) * 1992-10-12 1994-11-18 Synthelabo Dérivés de l'acide benzèneborinique, leur préparation et leur utilisation comme intermédiaires de synthèse.
DE4423061C1 (de) * 1994-07-01 1996-01-18 Hoechst Ag Verfahren zur Herstellung von Biphenylen mit Palladacyclen als Katalysatoren
DE4426671A1 (de) * 1994-07-28 1996-02-01 Hoechst Ag Verfahren zur Kreuzkupplung von aromatischen Borverbindungen mit aromatischen Halogenverbindungen oder Perfluoralkylsulfonaten
KR100354802B1 (ko) * 1994-10-20 2002-12-26 한국화학연구원 테트라졸유도체의제조방법
JP2928982B2 (ja) 1994-10-27 1999-08-03 住化ファインケム株式会社 ４’−ブロモメチル−２−シアノビフェニルの製造法
DE19620023C2 (de) * 1996-05-17 2001-03-08 Celanese Chem Europe Gmbh Verfahren zur Herstellung von Phosphinat- oder Phosphonatgruppen enthaltenden tertiären Phosphanen und neue Phosphinatgruppen enthaltende tertiäre Phosphane
US5922898A (en) * 1997-04-08 1999-07-13 Catalytica Pharmaceuticals, Inc. Process for preparing biaryl compounds
US6194599B1 (en) 1997-04-08 2001-02-27 Catalytica, Inc. Process for preparing biaryl compounds
WO1999047474A1 (en) 1998-03-18 1999-09-23 Ciba Specialty Chemicals Holding Inc. Coupling reactions with palladium catalysts
US6962999B2 (en) 2001-07-25 2005-11-08 Pharmacore, Inc. Process for preparing unsymmetrical biaryls and alkylated aromatic compounds from arylnitriles
DE10211597A1 (de) 2002-03-15 2003-10-02 Merck Patent Gmbh Verfahren zur Herstellung von Ringverbindungen
CA2482857A1 (en) 2002-04-29 2003-11-13 Teva Pharmaceutical Industries Ltd. Processes for preparing losartan and losartan potassium
KR100885148B1 (ko) 2002-06-12 2009-02-23 스미또모 가가꾸 가부시끼가이샤 4'-브로모메틸-2-시아노비페닐의 제조방법
US7105467B2 (en) 2003-07-08 2006-09-12 Pharmacore, Inc. Nickel catalyzed cross-coupling reactions between organomagnesium compounds and anisole derivatives
US7105707B2 (en) 2003-12-17 2006-09-12 Pharmacore, Inc. Process for preparing alkynyl-substituted aromatic and heterocyclic compounds
JP2006151946A (ja) * 2004-04-30 2006-06-15 Konishi Kagaku Ind Co Ltd ジアリール誘導体の製造方法
EP2170930B3 (en) 2007-06-04 2013-10-02 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2627848T3 (es) 2008-06-04 2017-07-31 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
KR101751249B1 (ko) * 2009-08-31 2017-06-27 바이엘 인텔렉쳐 프로퍼티 게엠베하 테트라아릴보레이트를 사용한 치환된 비페닐의 제조 방법
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
AU2014235215A1 (en) 2013-03-15 2015-10-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
US9486494B2 (en) 2013-03-15 2016-11-08 Synergy Pharmaceuticals, Inc. Compositions useful for the treatment of gastrointestinal disorders
CN105764916B (zh) 2013-06-05 2021-05-18 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
JP5975081B2 (ja) * 2013-09-30 2016-08-23 ダイキン工業株式会社 含フッ素ビアリール化合物の製造方法
DK4426434T3 (da) 2021-11-02 2025-11-10 Flare Therapeutics Inc Pparg inverse agonists and uses thereof
CN117623932A (zh) * 2023-11-30 2024-03-01 江苏康恒化工有限公司 中间体2，2’-二硝基联苯的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
DE3889461T2 (de) * 1987-10-19 1994-09-01 Secr Defence Brit Lateral cyano- und fluorosubstituierte terphenyle.
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
AP161A (en) * 1989-08-11 1991-12-20 Ici Plc Novel Quinoline derivatives.

Also Published As

Publication number Publication date
AU646473B2 (en) 1994-02-24
PL291370A1 (en) 1992-11-16
GB9115244D0 (en) 1991-08-28
YU137891A (sh) 1994-06-10
NZ239026A (en) 1993-12-23
GB9017482D0 (en) 1990-09-26
JPH04253949A (ja) 1992-09-09
HU912481D0 (en) 1991-12-30
NO174502C (show.php) 1994-05-18
RU2026285C1 (ru) 1995-01-09
EP0470795A1 (en) 1992-02-12
FI913640A0 (fi) 1991-07-30
CN1059516A (zh) 1992-03-18
FI913640A7 (fi) 1992-02-10
EP0470795B1 (en) 1995-01-25
EP0470795B2 (en) 2001-02-21
DE69106977T2 (de) 1995-05-24
DE69106977T3 (de) 2001-07-19
IL98862A0 (en) 1992-07-15
PT98608A (pt) 1992-06-30
ZW9591A1 (en) 1992-06-10
AU8043691A (en) 1992-02-13
NO913086D0 (no) 1991-08-08
JP3001298B2 (ja) 2000-01-24
NO174502B (no) 1994-02-07
CA2047369A1 (en) 1992-02-10
ATE117672T1 (de) 1995-02-15
HU207841B (en) 1993-06-28
CS241391A3 (en) 1992-03-18
KR920004337A (ko) 1992-03-27
HUT59662A (en) 1992-06-29
ZA915566B (en) 1992-04-29
NO913086L (no) 1992-02-10
DE69106977D1 (de) 1995-03-09
ES2067159T3 (es) 1995-03-16

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