TR200201216T2 - Interlökin-1 beta dönüştürücü enzim inhibitörleri. - Google Patents
Interlökin-1 beta dönüştürücü enzim inhibitörleri.Info
- Publication number
- TR200201216T2 TR200201216T2 TR2002/01216T TR200201216T TR200201216T2 TR 200201216 T2 TR200201216 T2 TR 200201216T2 TR 2002/01216 T TR2002/01216 T TR 2002/01216T TR 200201216 T TR200201216 T TR 200201216T TR 200201216 T2 TR200201216 T2 TR 200201216T2
- Authority
- TR
- Turkey
- Prior art keywords
- compounds
- diseases
- interleukin
- relates
- converting enzyme
- Prior art date
Links
- 239000005541 ACE inhibitor Substances 0.000 title 1
- 108090000426 Caspase-1 Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 6
- 230000000694 effects Effects 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- LOGFVTREOLYCPF-KXNHARMFSA-N (2s,3r)-2-[[(2r)-1-[(2s)-2,6-diaminohexanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoic acid Chemical compound C[C@@H](O)[C@@H](C(O)=O)NC(=O)[C@H]1CCCN1C(=O)[C@@H](N)CCCCN LOGFVTREOLYCPF-KXNHARMFSA-N 0.000 abstract 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 201000009030 Carcinoma Diseases 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 101000960954 Homo sapiens Interleukin-18 Proteins 0.000 abstract 1
- 102100037850 Interferon gamma Human genes 0.000 abstract 1
- 108010074328 Interferon-gamma Proteins 0.000 abstract 1
- 102000000589 Interleukin-1 Human genes 0.000 abstract 1
- 108010002352 Interleukin-1 Proteins 0.000 abstract 1
- 102000003777 Interleukin-1 beta Human genes 0.000 abstract 1
- 108090000193 Interleukin-1 beta Proteins 0.000 abstract 1
- 102100039898 Interleukin-18 Human genes 0.000 abstract 1
- 206010061363 Skeletal injury Diseases 0.000 abstract 1
- -1 apoptosis Proteins 0.000 abstract 1
- 230000006907 apoptotic process Effects 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 208000017443 reproductive system disease Diseases 0.000 abstract 1
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- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/575,641 US6008217A (en) | 1995-12-20 | 1995-12-20 | Inhibitors of interleukin-1β converting enzyme |
US08/598,332 US5874424A (en) | 1995-12-20 | 1996-02-08 | Inhibitors of interleukin-1β converting enzyme |
US08/712,878 US5985863A (en) | 1996-09-12 | 1996-09-12 | Compositions and methods for decreasing IGIF and IFN-γ production by administering an ICE inhibitor |
US3149596P | 1996-11-26 | 1996-11-26 | |
US08/761,483 US6204261B1 (en) | 1995-12-20 | 1996-12-06 | Inhibitors of interleukin-1β Converting enzyme inhibitors |
Publications (1)
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TR200201216T2 true TR200201216T2 (tr) | 2002-09-23 |
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Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2002/01216T TR200201216T2 (tr) | 1995-12-20 | 1996-12-20 | Interlökin-1 beta dönüştürücü enzim inhibitörleri. |
TR2002/01218T TR200201218T2 (tr) | 1995-12-20 | 1996-12-20 | Interlökin-1 beta dönüştürücü enzim inhibitörleri |
TR2002/01217T TR200201217T2 (tr) | 1995-12-20 | 1996-12-20 | İnterlökin-1 beta dönüştüren enzim inhibitörleri |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
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TR2002/01218T TR200201218T2 (tr) | 1995-12-20 | 1996-12-20 | Interlökin-1 beta dönüştürücü enzim inhibitörleri |
TR2002/01217T TR200201217T2 (tr) | 1995-12-20 | 1996-12-20 | İnterlökin-1 beta dönüştüren enzim inhibitörleri |
Country Status (23)
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US (7) | US6204261B1 (forum.php) |
EP (3) | EP0869967A2 (forum.php) |
JP (3) | JP4205762B2 (forum.php) |
KR (1) | KR100561504B1 (forum.php) |
CN (1) | CN1229412A (forum.php) |
AP (4) | AP0202540A0 (forum.php) |
AU (1) | AU735075B2 (forum.php) |
BG (2) | BG64465B1 (forum.php) |
BR (2) | BR9612258B1 (forum.php) |
CA (1) | CA2239904C (forum.php) |
CZ (2) | CZ298171B6 (forum.php) |
GE (1) | GEP20022638B (forum.php) |
IL (2) | IL124850A0 (forum.php) |
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IS (1) | IS4771A (forum.php) |
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NZ (2) | NZ326610A (forum.php) |
PL (1) | PL190736B1 (forum.php) |
SK (1) | SK287195B6 (forum.php) |
TR (3) | TR200201216T2 (forum.php) |
UA (1) | UA66337C2 (forum.php) |
WO (1) | WO1997022619A2 (forum.php) |
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-
1996
- 1996-12-06 US US08/761,483 patent/US6204261B1/en not_active Expired - Lifetime
- 1996-12-18 IN IN2188CA1996 patent/IN182290B/en unknown
- 1996-12-20 EP EP96945318A patent/EP0869967A2/en not_active Withdrawn
- 1996-12-20 CZ CZ0190698A patent/CZ298171B6/cs not_active IP Right Cessation
- 1996-12-20 EP EP10010860A patent/EP2295442A3/en not_active Withdrawn
- 1996-12-20 TR TR2002/01216T patent/TR200201216T2/xx unknown
- 1996-12-20 BR BRPI9612258-7A patent/BR9612258B1/pt not_active IP Right Cessation
- 1996-12-20 UA UA98073924A patent/UA66337C2/uk unknown
- 1996-12-20 IL IL12485096A patent/IL124850A0/xx unknown
- 1996-12-20 AP APAP/P/2002/002540A patent/AP0202540A0/en unknown
- 1996-12-20 WO PCT/US1996/020843 patent/WO1997022619A2/en active Search and Examination
- 1996-12-20 BR BRPI9612258A patent/BRPI9612258B8/pt unknown
- 1996-12-20 NZ NZ326610A patent/NZ326610A/xx not_active IP Right Cessation
- 1996-12-20 PL PL96328527A patent/PL190736B1/pl not_active IP Right Cessation
- 1996-12-20 CZ CZ20030411A patent/CZ300171B6/cs not_active IP Right Cessation
- 1996-12-20 AP AP2002002540A patent/AP2002002540A0/xx unknown
- 1996-12-20 GE GEAP19964412A patent/GEP20022638B/en unknown
- 1996-12-20 CN CN96199828A patent/CN1229412A/zh active Pending
- 1996-12-20 TR TR2002/01218T patent/TR200201218T2/xx unknown
- 1996-12-20 AU AU15222/97A patent/AU735075B2/en not_active Ceased
- 1996-12-20 SK SK842-98A patent/SK287195B6/sk not_active IP Right Cessation
- 1996-12-20 EP EP09004786A patent/EP2083014A3/en not_active Withdrawn
- 1996-12-20 AP APAP/P/2002/002538A patent/AP0202538A0/en unknown
- 1996-12-20 KR KR1020047011964A patent/KR100561504B1/ko not_active Expired - Fee Related
- 1996-12-20 CA CA002239904A patent/CA2239904C/en not_active Expired - Fee Related
- 1996-12-20 TR TR2002/01217T patent/TR200201217T2/xx unknown
- 1996-12-20 JP JP52309897A patent/JP4205762B2/ja not_active Expired - Fee Related
- 1996-12-20 NZ NZ518094A patent/NZ518094A/en not_active IP Right Cessation
- 1996-12-20 AP APAP/P/2002/002539A patent/AP0202539A0/en unknown
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1998
- 1998-06-05 NO NO19982597A patent/NO326882B1/no not_active IP Right Cessation
- 1998-06-11 IL IL124850A patent/IL124850A/en not_active IP Right Cessation
- 1998-06-12 IS IS4771A patent/IS4771A/is unknown
- 1998-06-19 MX MX9805016A patent/MX9805016A/es unknown
- 1998-07-13 BG BG102624A patent/BG64465B1/bg unknown
- 1998-07-13 BG BG108927A patent/BG108927A/en unknown
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1999
- 1999-09-21 US US09/400,639 patent/US6258948B1/en not_active Expired - Fee Related
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2001
- 2001-01-31 US US09/773,477 patent/US6423840B1/en not_active Expired - Fee Related
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2002
- 2002-01-28 US US10/058,522 patent/US20030225269A1/en not_active Abandoned
- 2002-10-21 JP JP2002306094A patent/JP2003137896A/ja not_active Withdrawn
-
2004
- 2004-11-29 US US10/999,865 patent/US20050143436A1/en not_active Abandoned
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2007
- 2007-01-18 US US11/655,938 patent/US7790713B2/en not_active Expired - Fee Related
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2008
- 2008-06-18 JP JP2008159803A patent/JP2008285493A/ja not_active Withdrawn
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2010
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