ATE285177T1 - Thiole zur förderung des wachstumsvon hömatopoietischen vorläuferzellen - Google Patents
Thiole zur förderung des wachstumsvon hömatopoietischen vorläuferzellenInfo
- Publication number
- ATE285177T1 ATE285177T1 AT96906519T AT96906519T ATE285177T1 AT E285177 T1 ATE285177 T1 AT E285177T1 AT 96906519 T AT96906519 T AT 96906519T AT 96906519 T AT96906519 T AT 96906519T AT E285177 T1 ATE285177 T1 AT E285177T1
- Authority
- AT
- Austria
- Prior art keywords
- growth
- cells
- progenicial
- hometopoietic
- thiole
- Prior art date
Links
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title 1
- 230000001737 promoting effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 210000003958 hematopoietic stem cell Anatomy 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000004936 stimulating effect Effects 0.000 abstract 2
- 208000030507 AIDS Diseases 0.000 abstract 1
- 201000003793 Myelodysplastic syndrome Diseases 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 150000003573 thiols Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/390,713 US5846958A (en) | 1995-02-17 | 1995-02-17 | Methods of using aminothiols to promote hematopoietic progenitor cell growth |
| PCT/US1996/002188 WO1996025045A1 (en) | 1995-02-17 | 1996-02-16 | Thiols to promote hematopoietic progenitor cell growth |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE285177T1 true ATE285177T1 (de) | 2005-01-15 |
Family
ID=23543611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96906519T ATE285177T1 (de) | 1995-02-17 | 1996-02-16 | Thiole zur förderung des wachstumsvon hömatopoietischen vorläuferzellen |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5846958A (de) |
| EP (1) | EP0809437B1 (de) |
| JP (1) | JP4057648B2 (de) |
| AT (1) | ATE285177T1 (de) |
| AU (1) | AU694847B2 (de) |
| CA (1) | CA2213322C (de) |
| DE (1) | DE69634074T2 (de) |
| ES (1) | ES2235183T3 (de) |
| PT (1) | PT809437E (de) |
| WO (1) | WO1996025045A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6573253B2 (en) | 1997-02-12 | 2003-06-03 | Medimmune Oncology Inc. | Methods for the administration of amifostine and related compounds |
| US6051563A (en) * | 1997-02-12 | 2000-04-18 | U.S. Bioscience, Inc. | Methods for the administration of amifostine and related compounds |
| US5994409A (en) * | 1997-12-09 | 1999-11-30 | U.S. Bioscience, Inc. | Methods for treatment of neuro--and nephro--disorders and therapeutic toxicities using aminothiol compounds |
| US6953777B2 (en) * | 1999-03-11 | 2005-10-11 | Genetics Indtitute LLC | Use of interleukin-11 to prevent immune-mediated cytotoxicity |
| US6489312B1 (en) * | 1999-06-15 | 2002-12-03 | Medimmune Oncology, Inc. | Pharmaceutical formulations comprising aminoalkyl phosphorothioates |
| JP5242877B2 (ja) | 2000-04-26 | 2013-07-24 | オレゴン ヘルス アンド サイエンス ユニバーシティー | チオールをベースとする化学保護剤の投与 |
| US7053072B2 (en) | 2001-05-11 | 2006-05-30 | Medimmune Oncology, Inc. | Methods for the administration of amifostine and related compounds |
| WO2003049693A2 (en) * | 2001-12-06 | 2003-06-19 | Wyeth | Method and composition for inducing weight loss |
| US6982080B2 (en) * | 2002-03-15 | 2006-01-03 | Wyeth | Hydroxyethyl starch—containing polypeptide compositions |
| AU2003296413A1 (en) * | 2002-09-16 | 2004-04-30 | Wyeth | Delayed release formulations for oral administration of a polypeptide therapeutic agent and methods of using same |
| WO2004039336A2 (en) * | 2002-10-31 | 2004-05-13 | Oregon Health & Science University | Use of thiol-based compositions in treating chemotherapeutic agent-induced thrombocytopenia |
| US20070148154A1 (en) * | 2004-12-17 | 2007-06-28 | Universite Rene Descartes (Paris V) | Use of superoxide dismutase mimetics and reductase gultatione in the form of anticancer drugs |
| WO2007096901A1 (en) * | 2006-02-24 | 2007-08-30 | Natco Pharma Limited | Novel dihydrate form of amifostine and process for its preparation |
| US20130230580A1 (en) * | 2010-09-14 | 2013-09-05 | Paul S. Frenette | Administration of SNS Neuroprotective Agents to Promote Hematopoietic Regeneration |
| JP6892132B2 (ja) | 2015-11-17 | 2021-06-18 | ザ バーリントン エイチシー リサーチ グループ インコーポレイテッド | アミノチオール及びその類似体の改善された保護及び送達のための方法 |
| GB201706544D0 (en) * | 2017-04-25 | 2017-06-07 | Plasticell Ltd | Method |
| RU2020108470A (ru) | 2017-07-28 | 2021-08-30 | Ниссан Кемикал Корпорейшн | Аддитивная композиция для культуральной среды, аддитивное соединение для культуральной среды и способ культивирования клеток или тканей с использованием этой композиции и соединения |
| GB201817385D0 (en) | 2018-10-25 | 2018-12-12 | Plasticell Ltd | Therapy |
| US20220144775A1 (en) | 2019-01-30 | 2022-05-12 | Nissan Chemical Corporation | Hydrazide compound and kinase inhibitor |
| GB202303026D0 (en) | 2023-03-01 | 2023-04-12 | Plasticell Ltd | Therapy |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3892824A (en) * | 1968-12-16 | 1975-07-01 | Southern Res Inst | S-{107 -({107 -aminoalkylamino)alkyl dihydrogen phosphorothioates |
| US4656034A (en) * | 1985-05-20 | 1987-04-07 | Survival Technology, Inc. | Absorption enhancing agents |
| EP0394542A1 (de) * | 1989-04-25 | 1990-10-31 | American Cyanamid Company | Wiederherstellung der Knochenmarkszellen mit synthetischen CSF-Induktoren |
| WO1991005571A1 (en) * | 1989-10-10 | 1991-05-02 | University Of Rochester | Method for producing bone marrow growth cell factors |
| MX9205549A (es) * | 1991-09-30 | 1993-05-01 | Jess G Thoene | Metodo para el tratamiento de vih. |
| US5824664A (en) * | 1993-03-26 | 1998-10-20 | U.S. Bioscience, Inc. | Suppression of HIV expression by organic thiophosphate |
-
1995
- 1995-02-17 US US08/390,713 patent/US5846958A/en not_active Expired - Lifetime
-
1996
- 1996-02-16 DE DE69634074T patent/DE69634074T2/de not_active Expired - Fee Related
- 1996-02-16 CA CA002213322A patent/CA2213322C/en not_active Expired - Fee Related
- 1996-02-16 PT PT96906519T patent/PT809437E/pt unknown
- 1996-02-16 WO PCT/US1996/002188 patent/WO1996025045A1/en not_active Ceased
- 1996-02-16 AT AT96906519T patent/ATE285177T1/de not_active IP Right Cessation
- 1996-02-16 JP JP52518996A patent/JP4057648B2/ja not_active Expired - Fee Related
- 1996-02-16 EP EP96906519A patent/EP0809437B1/de not_active Expired - Lifetime
- 1996-02-16 AU AU49869/96A patent/AU694847B2/en not_active Expired
- 1996-02-16 ES ES96906519T patent/ES2235183T3/es not_active Expired - Lifetime
-
1998
- 1998-03-24 US US09/046,870 patent/US5906984A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT809437E (pt) | 2005-05-31 |
| DE69634074T2 (de) | 2006-01-19 |
| EP0809437A1 (de) | 1997-12-03 |
| ES2235183T3 (es) | 2005-07-01 |
| AU4986996A (en) | 1996-09-04 |
| US5906984A (en) | 1999-05-25 |
| DE69634074D1 (de) | 2005-01-27 |
| WO1996025045A1 (en) | 1996-08-22 |
| CA2213322C (en) | 2008-05-13 |
| CA2213322A1 (en) | 1996-08-22 |
| EP0809437A4 (de) | 2001-05-09 |
| EP0809437B1 (de) | 2004-12-22 |
| JPH11504000A (ja) | 1999-04-06 |
| AU694847B2 (en) | 1998-07-30 |
| US5846958A (en) | 1998-12-08 |
| MX9706255A (es) | 1998-08-30 |
| JP4057648B2 (ja) | 2008-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0809437 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |