TR200201072T2 - 4-Triflorometilsulfinilpirazol türevi hazırlama süreci - Google Patents
4-Triflorometilsulfinilpirazol türevi hazırlama süreciInfo
- Publication number
- TR200201072T2 TR200201072T2 TR2002/01072T TR200201072T TR200201072T2 TR 200201072 T2 TR200201072 T2 TR 200201072T2 TR 2002/01072 T TR2002/01072 T TR 2002/01072T TR 200201072 T TR200201072 T TR 200201072T TR 200201072 T2 TR200201072 T2 TR 200201072T2
- Authority
- TR
- Turkey
- Prior art keywords
- trifluoromethylsulfinylpyrazole
- preparation process
- derivative preparation
- halogen
- haloalkyl
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- GMMUNQTZKMOWNL-UHFFFAOYSA-N 4-(trifluoromethylsulfinyl)-1h-pyrazole Chemical class FC(F)(F)S(=O)C=1C=NNC=1 GMMUNQTZKMOWNL-UHFFFAOYSA-N 0.000 title 1
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- XYPISWUKQGWYGX-UHFFFAOYSA-N 2,2,2-trifluoroethaneperoxoic acid Chemical compound OOC(=O)C(F)(F)F XYPISWUKQGWYGX-UHFFFAOYSA-N 0.000 abstract 1
- GYRPAYDYHMZXQT-KZULUSFZSA-N N-[(1S,5R)-3-[5-fluoro-2-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]-3-azabicyclo[3.1.0]hexan-1-yl]cyclopropanecarboxamide Chemical compound C1CC1C(=O)N[C@@]23C[C@@H]2CN(C3)C4=NC(=NC=C4F)NC5=CN(N=C5)CCO GYRPAYDYHMZXQT-KZULUSFZSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Formül (I) bilesiginin hazirlanisi için bir bulus, R halojeni, haloalkili, haloalkoksiyi, R4S(O)n- veya -SF5'i;, R hidrojen veya halojeni; R halojeni; R4 alkil veya haloalkili; ve n 0,1 veya 2'yi temsil eder; bu bulus formül (II) bilesiginin okside edilmesini içerir; burada asinma önleyici önündeki trifloroperasetik asitle bereaber R ,R ve W yukarida tanimlandigi gibidir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP1999/008687 WO2001030760A1 (en) | 1999-10-22 | 1999-10-22 | Process for preparing 4-trifluoromethylsulphinylpyrazole derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200201072T2 true TR200201072T2 (tr) | 2002-07-22 |
Family
ID=8167491
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2002/01072T TR200201072T2 (tr) | 1999-10-22 | 1999-10-22 | 4-Triflorometilsulfinilpirazol türevi hazırlama süreci |
TR2002/02806T TR200202806T2 (tr) | 1999-10-22 | 1999-10-22 | 4-Triflorometilsulfinilpirazol türevi hazırlama süreci |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2002/02806T TR200202806T2 (tr) | 1999-10-22 | 1999-10-22 | 4-Triflorometilsulfinilpirazol türevi hazırlama süreci |
Country Status (30)
Country | Link |
---|---|
US (2) | US6620943B1 (tr) |
EP (1) | EP1222173B1 (tr) |
JP (1) | JP4666863B2 (tr) |
KR (2) | KR100665598B1 (tr) |
CN (3) | CN101445483B (tr) |
AT (1) | ATE273961T1 (tr) |
AU (1) | AU783139B2 (tr) |
BG (1) | BG65483B1 (tr) |
BR (1) | BR9917518B1 (tr) |
CA (1) | CA2384283C (tr) |
CZ (1) | CZ299822B6 (tr) |
DE (1) | DE69919599T2 (tr) |
DK (1) | DK1222173T3 (tr) |
EA (1) | EA005077B1 (tr) |
ES (1) | ES2222743T3 (tr) |
HR (1) | HRP20020438B1 (tr) |
HU (1) | HU229393B1 (tr) |
IL (2) | IL149152A0 (tr) |
IN (2) | IN2005MU00818A (tr) |
ME (1) | MEP7808A (tr) |
MX (1) | MX229662B (tr) |
NZ (2) | NZ517770A (tr) |
PL (1) | PL206482B1 (tr) |
PT (1) | PT1222173E (tr) |
RO (1) | RO121209B1 (tr) |
TR (2) | TR200201072T2 (tr) |
TW (1) | TW553936B (tr) |
UA (1) | UA73752C2 (tr) |
WO (1) | WO2001030760A1 (tr) |
ZA (1) | ZA200201961B (tr) |
Families Citing this family (35)
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IL147272A0 (en) | 1999-06-29 | 2002-08-14 | Mitsubishi Chem Corp | Pyrazole derivatives and process for producing the same, and pesticides containing the same as the active ingredient |
WO2005023774A1 (en) * | 2003-09-11 | 2005-03-17 | Cheminova A/S | Process for the preparation of a trifluoromethylthioether |
CN100586934C (zh) * | 2003-11-07 | 2010-02-03 | 凯米诺瓦有限公司 | 制备三氟甲基硫醚的方法 |
DE102004020069C5 (de) | 2004-04-24 | 2013-12-05 | Voith Patent Gmbh | Verfahren zum Satinieren einer Papierbahn |
AU2013203228B2 (en) * | 2005-12-14 | 2015-08-27 | Makhteshim Chemical Works Ltd | Polymorphs and amorphous forms of 5-amino-1-[2,6- dichloro-4-(trifluoromethyl)phenyl]-4- [(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile |
CA2630849C (en) | 2005-12-14 | 2013-05-14 | Makhteshim Chemical Works Ltd. | Polymorphs and amorphous forms of 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1h-pyrazole-3-carbonitrile |
BRPI0621611B1 (pt) | 2006-04-25 | 2015-08-18 | Gharda Chemicals Ltd | Processo para a preparação de fipronila, inseticida e pirazóis relacionados |
CN101168529B (zh) * | 2006-10-24 | 2011-03-23 | 温州大学 | 氟虫腈、乙虫腈及其衍生物的合成方法 |
CA2667562A1 (en) | 2006-11-10 | 2008-05-15 | Basf Se | Process for the sulfinylation of a pyrazole derivative |
JP5931322B2 (ja) | 2006-11-10 | 2016-06-08 | ビーエーエスエフ ソシエタス・ヨーロピアBasf Se | フィプロニルの結晶変態 |
CA2667559A1 (en) | 2006-11-10 | 2008-05-15 | Basf Se | Process for the sulfinylation of a pyrazole derivative |
MX2009004323A (es) * | 2006-11-10 | 2009-05-05 | Basf Se | Nueva modificacion cristalina. |
BRPI0718715B8 (pt) | 2006-11-10 | 2021-03-23 | Basf Se | modificação cristalina iv de fipronil contendo acetona co-cristalizada, fipronil sólido, processos para preparar as modificações cristalinas iv, v e i, mistura pesticida ou parasiticida e composição pesticida ou parasiticida |
UA110598C2 (uk) | 2006-11-10 | 2016-01-25 | Басф Се | Спосіб одержання кристалічної модифікації фіпронілу |
CN101250158B (zh) * | 2008-04-02 | 2011-12-07 | 湖南化工研究院 | 一种氟虫腈的制备方法 |
EP2349987B1 (de) | 2008-10-02 | 2012-11-14 | Basf Se | Verfahren zur herstellung und aufreinigung von trifluormethansulfinsäure |
WO2010049746A1 (en) * | 2008-10-27 | 2010-05-06 | Dynamit Nobel Gmbh Explosivstoff-Und Systemtechnic | Process for the synthesis of fipronil |
EP2493860B1 (en) | 2009-10-30 | 2014-01-15 | Basf Se | Process for the preparation of 4-sulfinyl-pyrazole derivatives |
AU2010100462A4 (en) | 2010-03-03 | 2010-06-17 | Keki Hormusji Gharda | A process for the synthesis of Fipronil |
IT1400666B1 (it) | 2010-07-07 | 2013-06-28 | Finchimica Srl | Procedimento per la sintesi di 5-amino, 1-fenil, 3-ciano, 4-trifluorometil sulfinil pirazoli. |
CA2805227A1 (en) | 2010-07-12 | 2012-01-19 | Irvita Plant Protection, A Branch Of Celsius Property B.V. | Fipronil production process |
CN103313604B (zh) * | 2011-01-14 | 2016-03-02 | K·H·伽达 | [5-氨基-1-(2,6-二氯-4-三氟甲苯基)-3-腈-4-三氟甲基亚磺酰基吡唑]中的多晶体 |
EP2714664B1 (en) | 2011-05-30 | 2016-10-19 | Keki Hormusji Gharda | Process for synthesis of fipronil |
CN102633722B (zh) * | 2012-03-20 | 2015-05-06 | 金坛市凌云动物保健品有限公司 | 一种非泼罗尼的制备方法 |
TWI579274B (zh) * | 2012-04-20 | 2017-04-21 | 龍馬躍公司 | 製備1-芳基-5-烷基吡唑化合物的改良方法 |
CN102690232A (zh) * | 2012-05-30 | 2012-09-26 | 河南中医学院 | 一种氟虫腈中间体的合成方法 |
US9049860B2 (en) | 2013-04-17 | 2015-06-09 | The Hartz Mountain Corporation | Ectoparasiticidal methods |
CN105254565A (zh) * | 2015-09-30 | 2016-01-20 | 乐平市康鑫医药化工有限公司 | 由氰基吡唑一锅法合成硫醚的工艺方法 |
CN106977460A (zh) * | 2017-04-19 | 2017-07-25 | 江苏托球农化股份有限公司 | 1‑(2,6‑二氯‑4‑三氟甲基)苯基‑3‑氰基‑4‑乙巯基‑5‑氨基吡唑的合成 |
EP3412659A1 (en) | 2017-06-09 | 2018-12-12 | Solvay Sa | Processes for the manufacture of sulfur-substituted pyrazole derivatives |
EP3412658A1 (en) | 2017-06-09 | 2018-12-12 | Solvay Sa | Processes for the manufacture of sulfur-substitued pyrazole derivatives |
CN112430213A (zh) * | 2020-12-03 | 2021-03-02 | 江苏优普生物化学科技股份有限公司 | 一种三氟甲硫基吡唑合成工艺 |
CN113149909B (zh) * | 2021-03-24 | 2022-04-19 | 台州达辰药业有限公司 | 5-氨基-3-氰基-1-(2,6-二氯-4-三氟甲基-苯基)吡唑二硫化物制备方法 |
CN113480482B (zh) * | 2021-07-05 | 2022-11-18 | 海正药业南通有限公司 | 一种非泼罗尼中间体的合成方法 |
CN114213330A (zh) * | 2021-12-29 | 2022-03-22 | 天和药业股份有限公司 | 一种氟虫腈精制母液的处理方法 |
Family Cites Families (6)
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FR2716453B1 (fr) * | 1994-02-22 | 1996-03-29 | Rhone Poulenc Agrochimie | Procédé de sulfinylation de composés hétérocycliques. |
DE3602728A1 (de) * | 1985-05-17 | 1986-11-20 | Bayer Ag, 51373 Leverkusen | Schaedlingsbekaempfungsmittel auf basis von pyrazolderivaten |
US5232940A (en) | 1985-12-20 | 1993-08-03 | Hatton Leslie R | Derivatives of N-phenylpyrazoles |
US5547974A (en) * | 1985-12-20 | 1996-08-20 | Rhone-Poulenc Agriculture Ltd. | Derivatives of N-phenylpyrazoles |
GB8713768D0 (en) * | 1987-06-12 | 1987-07-15 | May & Baker Ltd | Compositions of matter |
CA2004776C (fr) * | 1988-12-13 | 2000-04-25 | Claude Wakselman | Procede de preparation de perfluoroalkylthioethers |
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1999
- 1999-10-22 US US10/111,000 patent/US6620943B1/en not_active Expired - Lifetime
- 1999-10-22 PL PL354611A patent/PL206482B1/pl not_active IP Right Cessation
- 1999-10-22 CN CN2008101863366A patent/CN101445483B/zh not_active Expired - Lifetime
- 1999-10-22 AT AT99955978T patent/ATE273961T1/de active
- 1999-10-22 BR BRPI9917518-5A patent/BR9917518B1/pt not_active IP Right Cessation
- 1999-10-22 TR TR2002/01072T patent/TR200201072T2/tr unknown
- 1999-10-22 AU AU12707/00A patent/AU783139B2/en not_active Expired
- 1999-10-22 ES ES99955978T patent/ES2222743T3/es not_active Expired - Lifetime
- 1999-10-22 KR KR1020027005011A patent/KR100665598B1/ko not_active IP Right Cessation
- 1999-10-22 RO ROA200200317A patent/RO121209B1/ro unknown
- 1999-10-22 HU HU0203206A patent/HU229393B1/hu unknown
- 1999-10-22 CA CA002384283A patent/CA2384283C/en not_active Expired - Fee Related
- 1999-10-22 ME MEP-78/08A patent/MEP7808A/xx unknown
- 1999-10-22 TR TR2002/02806T patent/TR200202806T2/tr unknown
- 1999-10-22 EA EA200200481A patent/EA005077B1/ru not_active IP Right Cessation
- 1999-10-22 WO PCT/EP1999/008687 patent/WO2001030760A1/en active Application Filing
- 1999-10-22 CN CNB998060828A patent/CN1163488C/zh not_active Expired - Lifetime
- 1999-10-22 MX MXPA02003944 patent/MX229662B/es active IP Right Grant
- 1999-10-22 DE DE69919599T patent/DE69919599T2/de not_active Expired - Lifetime
- 1999-10-22 UA UA2002054165A patent/UA73752C2/uk unknown
- 1999-10-22 NZ NZ517770A patent/NZ517770A/en not_active IP Right Cessation
- 1999-10-22 IL IL14915299A patent/IL149152A0/xx active IP Right Grant
- 1999-10-22 JP JP2001533114A patent/JP4666863B2/ja not_active Expired - Fee Related
- 1999-10-22 KR KR1020067017067A patent/KR100665599B1/ko not_active IP Right Cessation
- 1999-10-22 CZ CZ20021384A patent/CZ299822B6/cs not_active IP Right Cessation
- 1999-10-22 NZ NZ527896A patent/NZ527896A/en not_active IP Right Cessation
- 1999-10-22 DK DK99955978T patent/DK1222173T3/da active
- 1999-10-22 EP EP99955978A patent/EP1222173B1/en not_active Expired - Lifetime
- 1999-10-22 CN CN2004101300014A patent/CN1896066B/zh not_active Expired - Lifetime
- 1999-10-22 IN IN818MU2005 patent/IN2005MU00818A/en unknown
- 1999-10-22 PT PT99955978T patent/PT1222173E/pt unknown
-
2000
- 2000-10-11 TW TW089121214A patent/TW553936B/zh not_active IP Right Cessation
-
2002
- 2002-03-08 ZA ZA200201961A patent/ZA200201961B/en unknown
- 2002-04-01 IN IN312MU2002 patent/IN2002MU00312A/en unknown
- 2002-04-15 IL IL149152A patent/IL149152A/en not_active IP Right Cessation
- 2002-04-17 BG BG106622A patent/BG65483B1/bg unknown
- 2002-05-20 HR HR20020438A patent/HRP20020438B1/xx not_active IP Right Cessation
-
2003
- 2003-07-03 US US10/611,979 patent/US6881848B2/en not_active Expired - Fee Related
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