TR200200403T2 - Adrenalin üretimi için usul - Google Patents
Adrenalin üretimi için usulInfo
- Publication number
- TR200200403T2 TR200200403T2 TR2002/00403T TR200200403T TR200200403T2 TR 200200403 T2 TR200200403 T2 TR 200200403T2 TR 2002/00403 T TR2002/00403 T TR 2002/00403T TR 200200403 T TR200200403 T TR 200200403T TR 200200403 T2 TR200200403 T2 TR 200200403T2
- Authority
- TR
- Turkey
- Prior art keywords
- adrenaline
- procedure
- production
- methyl
- catalyst
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Abstract
Mevcut bulus adrenalin veya bunun bir ilave tuzunun endüstriyel boyutta bir asimetrik hidritleme isleminin anahtar islem olarak kullanilmasi ve sonraki islem asamalarinin özel sirasinin uygulanmasi altinda iyilestirilmis bir üretim usulü ile ilgili olup, bu usulde katalizör olarak [Rh(COD)Cl]2 ve bir siral, iki onluk fosfinligand örnegin (2R,4R)-4-(disikloheksilfosfino)-2- (difenilfosfino-metil) -N-metil-amino-karbonil-pirolidin katalizör sistemi olarak kullanilmaktadir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19938709A DE19938709C1 (de) | 1999-08-14 | 1999-08-14 | Verfahren zur Herstellung von Adrenalin |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200200403T2 true TR200200403T2 (tr) | 2002-05-21 |
Family
ID=7918496
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2002/00403T TR200200403T2 (tr) | 1999-08-14 | 2000-08-04 | Adrenalin üretimi için usul |
Country Status (29)
Country | Link |
---|---|
US (1) | US6218575B1 (tr) |
EP (1) | EP1210318B1 (tr) |
JP (1) | JP4594576B2 (tr) |
KR (1) | KR100666841B1 (tr) |
CN (1) | CN1179939C (tr) |
AR (1) | AR025105A1 (tr) |
AT (1) | ATE253549T1 (tr) |
AU (1) | AU766721B2 (tr) |
BR (1) | BR0013146B1 (tr) |
CA (1) | CA2381246C (tr) |
CO (1) | CO5190670A1 (tr) |
CZ (1) | CZ300938B6 (tr) |
DE (2) | DE19938709C1 (tr) |
DK (1) | DK1210318T3 (tr) |
EA (1) | EA004052B1 (tr) |
ES (1) | ES2209975T3 (tr) |
HK (1) | HK1048627B (tr) |
HU (1) | HU224529B1 (tr) |
IL (2) | IL147703A0 (tr) |
MX (1) | MXPA02001140A (tr) |
NZ (1) | NZ517369A (tr) |
PE (1) | PE20010492A1 (tr) |
PL (1) | PL200340B1 (tr) |
PT (1) | PT1210318E (tr) |
TR (1) | TR200200403T2 (tr) |
TW (1) | TWI256948B (tr) |
UY (1) | UY26283A1 (tr) |
WO (1) | WO2001012583A1 (tr) |
ZA (1) | ZA200201220B (tr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1579627A (zh) * | 2003-08-05 | 2005-02-16 | 中国科学院大连化学物理研究所 | 一种手性配体金属络合物催化体系及制法和应用 |
US20050197503A1 (en) * | 2004-03-05 | 2005-09-08 | Boehringer Ingelheim International Gmbh | Process for the preparation of N-alkyl-N-methyl-3-hydroxy-3-(2-thienyl)-propylamines |
DE102004033313A1 (de) * | 2004-07-08 | 2006-01-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung von Enantiomeren 3-hydroxy-3-phenyl-propylaminen |
JP4834333B2 (ja) * | 2005-06-27 | 2011-12-14 | アルプス薬品工業株式会社 | 光学活性ベンジルアミン誘導体の製造方法 |
WO2007145203A1 (ja) * | 2006-06-13 | 2007-12-21 | Daiichi Fine Chemical Co., Ltd. | 光学活性2-アミノ-1-(4-フルオロフェニル)エタノール |
WO2009004593A2 (en) * | 2007-07-03 | 2009-01-08 | Wockhardt Research Centre | Processes for the preparation of epinephrine |
US8436181B2 (en) | 2007-09-06 | 2013-05-07 | Nippon Soda Co., Ltd. | Production process of optically active 3-quinuclidinol derivative |
CN101983186B (zh) * | 2008-04-07 | 2013-12-11 | 日本曹达株式会社 | 钌化合物和光学活性氨基醇化合物的制造方法 |
CN101906457B (zh) * | 2010-08-05 | 2013-03-20 | 福州大学 | 一种生物不对称转化制备r-肾上腺素的方法 |
CN106397229B (zh) * | 2016-08-30 | 2018-06-29 | 蚌埠丰原医药科技发展有限公司 | 一种制备(r)-4-(2-(苄基(甲基)氨基)-羟乙基)苯-1,2-二醇的方法 |
IT201800004492A1 (it) * | 2018-04-13 | 2019-10-13 | Procedimento per la sintesi di beta-amminoalcoli otticamente attivi | |
EP3725765A1 (en) * | 2019-04-18 | 2020-10-21 | Edmond Pharma S.R.L. | A process for the preparation of enantiomerically pure norepinephrine |
CN117003651B (zh) * | 2023-09-28 | 2024-01-02 | 广东嘉博制药有限公司 | 一种l-肾上腺素的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE524717C (de) * | 1927-10-30 | 1931-05-11 | I G Farbenindustrie Akt Ges | Verfahren zur Darstellung von Aminoalkoholen der aromatischen Reihe |
EP0251164B1 (en) * | 1986-06-25 | 1992-12-16 | Kazuo Achiwa | New chiral phosphinopyrrolidine compounds and their use for asymetric synthesis of optically active compounds |
JP2617329B2 (ja) * | 1988-02-24 | 1997-06-04 | 富士薬品工業株式会社 | 光学活性なアミノアルコールの製造法 |
JP2816555B2 (ja) * | 1988-03-07 | 1998-10-27 | 富士薬品工業株式会社 | 新規なホスフイノピロリジン化合物およびそれを用いる不斉合成法 |
DE19902229C2 (de) * | 1999-01-21 | 2000-11-02 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von L-Phenylephrinhydrochlorid |
-
1999
- 1999-08-14 DE DE19938709A patent/DE19938709C1/de not_active Expired - Fee Related
-
2000
- 2000-07-26 US US09/625,881 patent/US6218575B1/en not_active Expired - Lifetime
- 2000-08-04 BR BRPI0013146-6A patent/BR0013146B1/pt not_active IP Right Cessation
- 2000-08-04 WO PCT/EP2000/007573 patent/WO2001012583A1/de active IP Right Grant
- 2000-08-04 HU HU0203201A patent/HU224529B1/hu not_active IP Right Cessation
- 2000-08-04 AU AU72722/00A patent/AU766721B2/en not_active Ceased
- 2000-08-04 JP JP2001516884A patent/JP4594576B2/ja not_active Expired - Fee Related
- 2000-08-04 IL IL14770300A patent/IL147703A0/xx active IP Right Grant
- 2000-08-04 DE DE50004356T patent/DE50004356D1/de not_active Expired - Lifetime
- 2000-08-04 AT AT00960392T patent/ATE253549T1/de active
- 2000-08-04 EP EP00960392A patent/EP1210318B1/de not_active Expired - Lifetime
- 2000-08-04 CZ CZ20020514A patent/CZ300938B6/cs not_active IP Right Cessation
- 2000-08-04 TR TR2002/00403T patent/TR200200403T2/tr unknown
- 2000-08-04 EA EA200200205A patent/EA004052B1/ru not_active IP Right Cessation
- 2000-08-04 KR KR1020027001801A patent/KR100666841B1/ko active IP Right Grant
- 2000-08-04 CA CA002381246A patent/CA2381246C/en not_active Expired - Lifetime
- 2000-08-04 PL PL353394A patent/PL200340B1/pl unknown
- 2000-08-04 PT PT00960392T patent/PT1210318E/pt unknown
- 2000-08-04 DK DK00960392T patent/DK1210318T3/da active
- 2000-08-04 MX MXPA02001140A patent/MXPA02001140A/es active IP Right Grant
- 2000-08-04 CN CNB008115753A patent/CN1179939C/zh not_active Expired - Fee Related
- 2000-08-04 NZ NZ517369A patent/NZ517369A/en unknown
- 2000-08-04 ES ES00960392T patent/ES2209975T3/es not_active Expired - Lifetime
- 2000-08-08 UY UY26283A patent/UY26283A1/es not_active Application Discontinuation
- 2000-08-11 CO CO00060337A patent/CO5190670A1/es not_active Application Discontinuation
- 2000-08-11 TW TW089116158A patent/TWI256948B/zh not_active IP Right Cessation
- 2000-08-11 PE PE2000000817A patent/PE20010492A1/es not_active Application Discontinuation
- 2000-08-11 AR ARP000104153A patent/AR025105A1/es active Pending
-
2002
- 2002-01-17 IL IL147703A patent/IL147703A/en not_active IP Right Cessation
- 2002-02-13 ZA ZA200201220A patent/ZA200201220B/en unknown
-
2003
- 2003-02-06 HK HK03100838.3A patent/HK1048627B/zh not_active IP Right Cessation
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