TR200103685T2 - Optik olarak aktif pirrolopiridazin türevleri - Google Patents

Optik olarak aktif pirrolopiridazin türevleri

Info

Publication number
TR200103685T2
TR200103685T2 TR2001/03685T TR200103685T TR200103685T2 TR 200103685 T2 TR200103685 T2 TR 200103685T2 TR 2001/03685 T TR2001/03685 T TR 2001/03685T TR 200103685 T TR200103685 T TR 200103685T TR 200103685 T2 TR200103685 T2 TR 200103685T2
Authority
TR
Turkey
Prior art keywords
optically active
pyrolopyridazine
derivatives
formula
alkyl
Prior art date
Application number
TR2001/03685T
Other languages
English (en)
Inventor
Hagihara Masahiko
Shibakawa Nobuhiko
Matsunobu Keiji
Fujiwara Hiroshi
Ito Keiichi
Original Assignee
Sankyo Company Limited
Ube Industries, Ltd.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Company Limited, Ube Industries, Ltd., filed Critical Sankyo Company Limited
Publication of TR200103685T2 publication Critical patent/TR200103685T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

R' in alkil; R2 ve R3'ün ayri ayri alkil, R4' ün tercihe göre ikameli aril ve A' nin imino, oksijen veya sülfür oldugu bir formül (I): optik aktif pirrolopiridazin türevi veya farmasötik olarak kabul edilebilir bir tuzu.(FORMÜL VAR)
TR2001/03685T 1999-06-15 2000-06-15 Optik olarak aktif pirrolopiridazin türevleri TR200103685T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16767999 1999-06-15

Publications (1)

Publication Number Publication Date
TR200103685T2 true TR200103685T2 (tr) 2002-05-21

Family

ID=15854223

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03685T TR200103685T2 (tr) 1999-06-15 2000-06-15 Optik olarak aktif pirrolopiridazin türevleri

Country Status (25)

Country Link
US (1) US6670360B2 (tr)
EP (1) EP1186607B1 (tr)
KR (1) KR100583663B1 (tr)
CN (1) CN1170829C (tr)
AT (1) ATE240957T1 (tr)
AU (1) AU757611B2 (tr)
BR (1) BR0011666A (tr)
CA (1) CA2375848A1 (tr)
CZ (1) CZ290935B6 (tr)
DE (1) DE60002860T2 (tr)
DK (1) DK1186607T3 (tr)
ES (1) ES2198319T3 (tr)
HK (1) HK1044341B (tr)
HU (1) HUP0201434A3 (tr)
IL (2) IL147088A0 (tr)
MX (1) MXPA01013011A (tr)
NO (1) NO20016099L (tr)
NZ (1) NZ516194A (tr)
PL (1) PL356479A1 (tr)
PT (1) PT1186607E (tr)
RU (1) RU2222541C2 (tr)
TR (1) TR200103685T2 (tr)
TW (1) TWI287014B (tr)
WO (1) WO2000077003A1 (tr)
ZA (1) ZA200110279B (tr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1254907B1 (en) * 2000-02-10 2007-05-09 Sankyo Company, Limited Pyrrolopyridazine compound
TW200420293A (en) * 2002-09-25 2004-10-16 Sankyo Co Pharmaceutical compositions for the reduction of gastric acid concentration in blood
AU2003266621A1 (en) * 2002-09-25 2004-04-19 Sankyo Company, Limited Medicinal composition for treatment for or prevention of visceral pain
EP1682133A1 (en) 2003-11-03 2006-07-26 AstraZeneca AB Imidazo 1,2-a pyridine derivatives for the treatment of silent gastro-esophageal reflux
JP4989478B2 (ja) * 2004-09-03 2012-08-01 ユーハン・コーポレイション ピロロ［３，２−ｂ］ピリジン誘導体及びその製造方法
CN101003537A (zh) * 2006-01-17 2007-07-25 上海恒瑞医药有限公司 吡咯并哒嗪类衍生物及其制备方法和用途
US8648080B2 (en) 2009-07-09 2014-02-11 Raqualia Pharma Inc. Acid pump antagonist for the treatment of diseases involved in abnormal gastrointestinal motility
CN105367550A (zh) * 2014-08-11 2016-03-02 江苏柯菲平医药股份有限公司 四氢环戊二烯并[c]吡咯类衍生物、其制备方法及其在医药上的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991017164A1 (de) 1990-04-27 1991-11-14 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue pyridazine
WO1992006979A1 (de) 1990-10-15 1992-04-30 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue diazine
DK0609328T3 (da) 1991-10-25 1999-10-25 Byk Gulden Lomberg Chem Fab Pyrrolo-pyridaziner med gastro-intestinal beskyttelsesvirkning
DE69529056T2 (de) * 1994-01-19 2003-11-13 Sankyo Co Pyrrolopyridazin-derivate

Also Published As

Publication number Publication date
CA2375848A1 (en) 2000-12-21
HK1044341A1 (en) 2002-10-18
CN1370172A (zh) 2002-09-18
ATE240957T1 (de) 2003-06-15
US6670360B2 (en) 2003-12-30
US20020156079A1 (en) 2002-10-24
CN1170829C (zh) 2004-10-13
WO2000077003A1 (fr) 2000-12-21
TWI287014B (en) 2007-09-21
ES2198319T3 (es) 2004-02-01
EP1186607A4 (en) 2002-07-03
CZ290935B6 (cs) 2002-11-13
NO20016099L (no) 2002-02-07
PL356479A1 (en) 2004-06-28
PT1186607E (pt) 2003-08-29
AU5426900A (en) 2001-01-02
DE60002860D1 (de) 2003-06-26
EP1186607A1 (en) 2002-03-13
AU757611B2 (en) 2003-02-27
MXPA01013011A (es) 2002-11-07
NO20016099D0 (no) 2001-12-14
HUP0201434A2 (en) 2002-08-28
IL147088A0 (en) 2002-08-14
KR100583663B1 (ko) 2006-05-26
BR0011666A (pt) 2002-03-19
ZA200110279B (en) 2003-05-28
DE60002860T2 (de) 2004-05-06
EP1186607B1 (en) 2003-05-21
NZ516194A (en) 2003-03-28
KR20020022703A (ko) 2002-03-27
DK1186607T3 (da) 2003-09-01
IL147088A (en) 2006-12-31
RU2222541C2 (ru) 2004-01-27
CZ20014505A3 (cs) 2002-05-15
HK1044341B (zh) 2003-10-03
HUP0201434A3 (en) 2003-09-29

Similar Documents

Publication Publication Date Title
TR200100693T2 (tr) Azetidin türevleri, hazırlanmaları ve bunları içeren ilaçlar
TR199901847T2 (tr) Fosfolipaz az inhibitör aktivitesi olan pirrolidin türevleri.
FI953968A0 (fi) Antraniiliset happojohdannaiset
ATE342256T1 (de) Chinazolinderivate als medikamente
TR200200579T2 (tr) Amino-tirazolpiridin türevleri.
DE69720773T2 (de) SAUERSTOFF ODER SCHWEFEL ENTHALTENDE 5-GLIEDRIGE HETEROAROMATISHE DERIVATIVE ALS FACTOR Xa HEMMER
DE60140456D1 (de) Aza heterocyclische derivate und ihre therapeutische verwendung
NO20014317D0 (no) Pyrimidinforbindelser
CO5280078A1 (es) Compuestos
CO5031285A1 (es) Triarilimidazoles
BR0001569A (pt) Inibidores da uroquinase do tipo 2-piridinilguanidina
PT1086178E (pt) Antraquinona e seus derivados
TR200002605T2 (tr) Nitrik oksit sentaz inhibitörleri olarak faydalı halojene amidino amino asit türevleri
MXPA02006329A (es) 8-arilquinolinas sustituidas que son inhibidores de fosfodiesterasa-4.
TR200103685T2 (tr) Optik olarak aktif pirrolopiridazin türevleri
DE69505470T2 (de) Pyrrolocarbazol
DE69821530D1 (de) Dihydrobenzifurane
ATE302772T1 (de) 2-(1h-indol-3-yl)-2-oxo-acetamide mit antitumoraler wirkung
DE69903053T2 (de) Diaminocyclobuten-3,4-dionderivate, deren herstellung und deren verwendung
DE60036558D1 (de) Phthalazinon-derivate als pde 4 hemmer
DE60014932D1 (de) Diazocindionderivate und ihre verwendung als tryptase inhibitoren
PT1280779E (pt) Novos indanilimidazois policiclicos com actividade adrenergica alfa2
ES2159489A1 (es) Nuevos derivados de imidazol con actividad antiinflamatoria.
ATE552003T1 (de) Chinoxalinderivate
BR0110328A (pt) Compostos heterocìclicos com atividade antiinflamatória