IL147088A0 - Optically active pyrrolpyridazine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof - Google Patents
Optically active pyrrolpyridazine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereofInfo
- Publication number
- IL147088A0 IL147088A0 IL14708800A IL14708800A IL147088A0 IL 147088 A0 IL147088 A0 IL 147088A0 IL 14708800 A IL14708800 A IL 14708800A IL 14708800 A IL14708800 A IL 14708800A IL 147088 A0 IL147088 A0 IL 147088A0
- Authority
- IL
- Israel
- Prior art keywords
- optically active
- derivatives
- pyrrolpyridazine
- processes
- preparation
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- YTJAMOLQXDNLJC-UHFFFAOYSA-N N1N=CC=C2N=CC=C21 Chemical class N1N=CC=C2N=CC=C21 YTJAMOLQXDNLJC-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 241000590002 Helicobacter pylori Species 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 210000004211 gastric acid Anatomy 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 229940037467 helicobacter pylori Drugs 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 210000004400 mucous membrane Anatomy 0.000 abstract 1
- ODUCDPQEXGNKDN-UHFFFAOYSA-N nitroxyl Chemical compound O=N ODUCDPQEXGNKDN-UHFFFAOYSA-N 0.000 abstract 1
- 230000003248 secreting effect Effects 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16767999 | 1999-06-15 | ||
| PCT/JP2000/003895 WO2000077003A1 (fr) | 1999-06-15 | 2000-06-15 | Composes de pyrrolopyridazine optiquement actifs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL147088A0 true IL147088A0 (en) | 2002-08-14 |
Family
ID=15854223
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14708800A IL147088A0 (en) | 1999-06-15 | 2000-06-15 | Optically active pyrrolpyridazine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof |
| IL147088A IL147088A (en) | 1999-06-15 | 2001-12-13 | History 1 - (S1,2S) - 2, 3 - Dialkil - 7 - Transformed - 1H - Pyrrole - 2, 3 - d] Pyridicine with optical activity, pharmaceutical preparations containing them and methods for their preparation |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL147088A IL147088A (en) | 1999-06-15 | 2001-12-13 | History 1 - (S1,2S) - 2, 3 - Dialkil - 7 - Transformed - 1H - Pyrrole - 2, 3 - d] Pyridicine with optical activity, pharmaceutical preparations containing them and methods for their preparation |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6670360B2 (xx) |
| EP (1) | EP1186607B1 (xx) |
| KR (1) | KR100583663B1 (xx) |
| CN (1) | CN1170829C (xx) |
| AT (1) | ATE240957T1 (xx) |
| AU (1) | AU757611B2 (xx) |
| BR (1) | BR0011666A (xx) |
| CA (1) | CA2375848A1 (xx) |
| CZ (1) | CZ290935B6 (xx) |
| DE (1) | DE60002860T2 (xx) |
| DK (1) | DK1186607T3 (xx) |
| ES (1) | ES2198319T3 (xx) |
| HK (1) | HK1044341B (xx) |
| HU (1) | HUP0201434A3 (xx) |
| IL (2) | IL147088A0 (xx) |
| MX (1) | MXPA01013011A (xx) |
| NO (1) | NO20016099L (xx) |
| NZ (1) | NZ516194A (xx) |
| PL (1) | PL356479A1 (xx) |
| PT (1) | PT1186607E (xx) |
| RU (1) | RU2222541C2 (xx) |
| TR (1) | TR200103685T2 (xx) |
| TW (1) | TWI287014B (xx) |
| WO (1) | WO2000077003A1 (xx) |
| ZA (1) | ZA200110279B (xx) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0204579A3 (en) * | 2000-02-10 | 2006-01-30 | Ube Industries | Pyrrolopyridazine derivatives, pharmaceutical compositions containing them and their use |
| WO2004029057A1 (ja) * | 2002-09-25 | 2004-04-08 | Sankyo Company, Limited | 内臓痛の治療または予防のための医薬組成物 |
| WO2004029058A1 (ja) * | 2002-09-25 | 2004-04-08 | Sankyo Company, Limited | 血中ガストリン濃度上昇の抑制のための医薬組成物 |
| EP1974730A1 (en) | 2003-11-03 | 2008-10-01 | AstraZeneca AB | Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux |
| CN101010321B (zh) | 2004-09-03 | 2011-10-26 | 株式会社柳韩洋行 | 吡咯并[3,2-b]吡啶衍生物及其制备方法 |
| CN101003537A (zh) * | 2006-01-17 | 2007-07-25 | 上海恒瑞医药有限公司 | 吡咯并哒嗪类衍生物及其制备方法和用途 |
| CN105919998B (zh) | 2009-07-09 | 2021-08-24 | 拉夸里亚创药株式会社 | 用于治疗与异常肠胃运动有关的疾病的酸泵拮抗剂 |
| CN105367550A (zh) * | 2014-08-11 | 2016-03-02 | 江苏柯菲平医药股份有限公司 | 四氢环戊二烯并[c]吡咯类衍生物、其制备方法及其在医药上的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991017164A1 (de) | 1990-04-27 | 1991-11-14 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Neue pyridazine |
| AU8712191A (en) | 1990-10-15 | 1992-05-20 | Byk Gulden Lomberg Chemische Fabrik Gmbh | New diazines |
| JPH07500329A (ja) | 1991-10-25 | 1995-01-12 | ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | ピロロ−ピリダジン |
| ES2185693T3 (es) | 1994-01-19 | 2003-05-01 | Sankyo Co | Derivado de pirrolopiridacina. |
-
2000
- 2000-06-13 TW TW089111505A patent/TWI287014B/zh not_active IP Right Cessation
- 2000-06-15 PT PT00939072T patent/PT1186607E/pt unknown
- 2000-06-15 IL IL14708800A patent/IL147088A0/xx not_active IP Right Cessation
- 2000-06-15 CN CNB008115990A patent/CN1170829C/zh not_active Expired - Fee Related
- 2000-06-15 PL PL00356479A patent/PL356479A1/xx not_active Application Discontinuation
- 2000-06-15 TR TR2001/03685T patent/TR200103685T2/xx unknown
- 2000-06-15 KR KR1020017016061A patent/KR100583663B1/ko not_active IP Right Cessation
- 2000-06-15 HU HU0201434A patent/HUP0201434A3/hu unknown
- 2000-06-15 EP EP00939072A patent/EP1186607B1/en not_active Expired - Lifetime
- 2000-06-15 DE DE60002860T patent/DE60002860T2/de not_active Expired - Fee Related
- 2000-06-15 ES ES00939072T patent/ES2198319T3/es not_active Expired - Lifetime
- 2000-06-15 DK DK00939072T patent/DK1186607T3/da active
- 2000-06-15 CA CA002375848A patent/CA2375848A1/en not_active Abandoned
- 2000-06-15 RU RU2001134010/04A patent/RU2222541C2/ru not_active IP Right Cessation
- 2000-06-15 BR BR0011666-1A patent/BR0011666A/pt not_active IP Right Cessation
- 2000-06-15 AT AT00939072T patent/ATE240957T1/de not_active IP Right Cessation
- 2000-06-15 MX MXPA01013011A patent/MXPA01013011A/es active IP Right Grant
- 2000-06-15 CZ CZ20014505A patent/CZ290935B6/cs not_active IP Right Cessation
- 2000-06-15 AU AU54269/00A patent/AU757611B2/en not_active Ceased
- 2000-06-15 WO PCT/JP2000/003895 patent/WO2000077003A1/ja active IP Right Grant
- 2000-06-15 NZ NZ516194A patent/NZ516194A/xx unknown
-
2001
- 2001-12-12 US US10/021,214 patent/US6670360B2/en not_active Expired - Fee Related
- 2001-12-13 IL IL147088A patent/IL147088A/en unknown
- 2001-12-13 ZA ZA200110279A patent/ZA200110279B/xx unknown
- 2001-12-14 NO NO20016099A patent/NO20016099L/no not_active Application Discontinuation
-
2002
- 2002-08-14 HK HK02105957.8A patent/HK1044341B/zh not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL205420A (en) | Immunogoldular and Derivative Compounds, Pharmaceutical Compounds in the Treatment of Inflammatory Stomach and Gastrointestinal Disorders | |
| ATE260255T1 (de) | 5-oxo-pyrrolidine-2-carbonsäure- hydroxamidderivate | |
| AU1282495A (en) | Anthranilic acid derivative | |
| PL359415A1 (en) | Oxadiazole derivatives having anticancer effects | |
| IL147088A0 (en) | Optically active pyrrolpyridazine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof | |
| ATE240949T1 (de) | Epoxysuccinamid-derivate oder ihre salze | |
| DE60123827D1 (en) | 1-methylcarbapenemderivate | |
| NO323556B1 (no) | Forbindelser, farmasoytiske preparater som omfatter forbindelsene, og anvendelse av forbindelsene ved fremstilling av antibakterielle medikamenter. | |
| MXPA04000485A (es) | Uso de acidos aril o heteroaril hidroxamicos de sulfonilo y derivados de los mismos como inhibidores de agrecanasa. | |
| AU8003594A (en) | Quinolinecarboxylic acid derivative and salt thereof | |
| IL151167A0 (en) | Pyrrolopyridazine derivatives and pharmaceutical compositions containing the same | |
| EP0450232A3 (en) | P-guanidino benzoic acid derivatives for treatment of cerebrovascular contraction | |
| PL304334A1 (en) | Pharmaceutical composition of gastric protective action, including antiulceric one and method of treating diseases of gastrointestinal tract |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| MM9K | Patent not in force due to non-payment of renewal fees |