TR200103562T2 - Amiloid proteini toplanmasını önleme ve amiloid birikintilerini görüntüleme yönteminde kullanım için rodanin türevleri - Google Patents

Amiloid proteini toplanmasını önleme ve amiloid birikintilerini görüntüleme yönteminde kullanım için rodanin türevleri

Info

Publication number
TR200103562T2
TR200103562T2 TR2001/03562T TR200103562T TR200103562T2 TR 200103562 T2 TR200103562 T2 TR 200103562T2 TR 2001/03562 T TR2001/03562 T TR 2001/03562T TR 200103562 T TR200103562 T TR 200103562T TR 200103562 T2 TR200103562 T2 TR 200103562T2
Authority
TR
Turkey
Prior art keywords
protein aggregation
amyloid
preventing
imaging
rhodanine derivatives
Prior art date
Application number
TR2001/03562T
Other languages
English (en)
Turkish (tr)
Inventor
Elizabeth Augelli-Szafran Corinne
Ann Glase Shelly
Craswell Walker Lary
Yasunaga Tomoyuki
Original Assignee
Warner-Lambert Company
Yamanouchi Pharmaceutical Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company, Yamanouchi Pharmaceutical Company filed Critical Warner-Lambert Company
Publication of TR200103562T2 publication Critical patent/TR200103562T2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
TR2001/03562T 1999-06-10 2000-05-31 Amiloid proteini toplanmasını önleme ve amiloid birikintilerini görüntüleme yönteminde kullanım için rodanin türevleri TR200103562T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13854499P 1999-06-10 1999-06-10

Publications (1)

Publication Number Publication Date
TR200103562T2 true TR200103562T2 (tr) 2002-04-22

Family

ID=22482512

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03562T TR200103562T2 (tr) 1999-06-10 2000-05-31 Amiloid proteini toplanmasını önleme ve amiloid birikintilerini görüntüleme yönteminde kullanım için rodanin türevleri

Country Status (8)

Country Link
EP (1) EP1192143A1 (pt)
JP (1) JP2003502320A (pt)
AU (1) AU5311800A (pt)
BR (1) BR0011441A (pt)
CA (1) CA2374616A1 (pt)
MX (1) MXPA01010490A (pt)
TR (1) TR200103562T2 (pt)
WO (1) WO2000076987A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20020394A1 (es) 2000-08-18 2002-06-21 Agouron Pharma Compuestos de pirazol y composiciones farmaceuticas que los contienen, que modulan y/o inhiben la actividad de erab/hadh2
JP2006510661A (ja) 2002-12-06 2006-03-30 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー Ｐｉ３ｋの阻害剤としてのベンズオキサジン−３−オン類及びその誘導体
WO2005007123A2 (en) * 2003-07-18 2005-01-27 Pintex Pharmaceuticals, Inc. Pin1-modulating compounds and methods of use thereof
EP2121633A2 (en) 2007-02-12 2009-11-25 Merck & Co., Inc. Piperazine derivatives for treatment of ad and related conditions
CN103402516B (zh) 2010-06-17 2018-01-30 富津世生物技术有限公司 用作抗病毒药物的化合物、组合物及使用方法
CN106045986B (zh) * 2016-05-31 2019-12-06 广东工业大学 一种新型吩噻嗪衍生物及其制备方法与应用
CN106045987B (zh) * 2016-06-21 2019-04-23 广东工业大学 一种具有多功能近红外荧光磁性纳米微粒及其制备和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5740478A (en) * 1980-08-22 1982-03-06 Ono Pharmaceut Co Ltd Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative
JPH01147476A (ja) * 1987-12-03 1989-06-09 Mita Ind Co Ltd 光導電性トナー
JPH01147462A (ja) * 1987-12-03 1989-06-09 Mita Ind Co Ltd 電荷発生材料およびその製法
US5143929A (en) * 1991-05-09 1992-09-01 Warner-Lambert Company 2-substituted thiazolidinone, oxazolidinone, and imidazolidinone derivatives of fenamates as antiinflammatory agents
CZ181493A3 (en) * 1992-09-10 1994-03-16 Lilly Co Eli The use of rhodanine derivative for the preparation of a pharmaceutical composition reducing level of sugar in blood and for treating alzheimer's disease
DE4318550A1 (de) * 1993-06-04 1994-12-08 Boehringer Mannheim Gmbh Aryliden-4-oxo-2-thioxo-3- thiazolidincarbonsäuren, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US6251928B1 (en) * 1994-03-16 2001-06-26 Eli Lilly And Company Treatment of alzheimer's disease employing inhibitors of cathepsin D
WO1997026919A2 (en) * 1996-01-24 1997-07-31 Warner-Lambert Company Method of imaging amyloid deposits
CN1325309A (zh) * 1998-08-21 2001-12-05 维洛药品公司 用于治疗或预防病毒感染和相关疾病的化合物、组合物和方法
AU6330799A (en) * 1998-09-30 2000-04-17 Roche Diagnostics Gmbh Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders

Also Published As

Publication number Publication date
BR0011441A (pt) 2002-07-16
AU5311800A (en) 2001-01-02
EP1192143A1 (en) 2002-04-03
WO2000076987A1 (en) 2000-12-21
MXPA01010490A (es) 2005-05-27
JP2003502320A (ja) 2003-01-21
CA2374616A1 (en) 2000-12-21

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