BR0011441A - Derivados de rodanina para uso em um método de inibição da agregação da proteìna amilóide e formação de imagens de depósitos amilóides - Google Patents
Derivados de rodanina para uso em um método de inibição da agregação da proteìna amilóide e formação de imagens de depósitos amilóidesInfo
- Publication number
- BR0011441A BR0011441A BR0011441-3A BR0011441A BR0011441A BR 0011441 A BR0011441 A BR 0011441A BR 0011441 A BR0011441 A BR 0011441A BR 0011441 A BR0011441 A BR 0011441A
- Authority
- BR
- Brazil
- Prior art keywords
- imaging
- amyloid
- inhibiting
- protein aggregation
- deposits
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Abstract
"DERIVADOS DE RODANINA PARA USO EM UM MéTODO DE INIBIçãO DA AGREGAçãO DA PROTEìNA AMILóIDE E FORMAçãO DE IMAGENS DE DEPóSITOS AMILóIDES". A presente invenção proporcionar um método de tratamento de mal de Alzheimer usando-se um composto da Fórmula (I). Também proporcionado é um método de inibição da agregação de proteínas amilóides usando-se um composto da Fórmula (I) e um método de formação de imagens de depósitos amilóides usando-se os compostos da Fórmula (I).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13854499P | 1999-06-10 | 1999-06-10 | |
PCT/US2000/015069 WO2000076987A1 (en) | 1999-06-10 | 2000-05-31 | Rhodanine derivatives for use in a method of inhibiting amyloid protein aggregation and imaging amyloid deposits |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0011441A true BR0011441A (pt) | 2002-07-16 |
Family
ID=22482512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0011441-3A BR0011441A (pt) | 1999-06-10 | 2000-05-31 | Derivados de rodanina para uso em um método de inibição da agregação da proteìna amilóide e formação de imagens de depósitos amilóides |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1192143A1 (pt) |
JP (1) | JP2003502320A (pt) |
AU (1) | AU5311800A (pt) |
BR (1) | BR0011441A (pt) |
CA (1) | CA2374616A1 (pt) |
MX (1) | MXPA01010490A (pt) |
TR (1) | TR200103562T2 (pt) |
WO (1) | WO2000076987A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20020394A1 (es) | 2000-08-18 | 2002-06-21 | Agouron Pharma | Compuestos de pirazol y composiciones farmaceuticas que los contienen, que modulan y/o inhiben la actividad de erab/hadh2 |
WO2004052373A1 (en) | 2002-12-06 | 2004-06-24 | Warner-Lambert Company Llc | Benzoxazin-3-ones and derivatives thereof as inhibitors of pi3k |
WO2005007123A2 (en) * | 2003-07-18 | 2005-01-27 | Pintex Pharmaceuticals, Inc. | Pin1-modulating compounds and methods of use thereof |
EP2121633A2 (en) | 2007-02-12 | 2009-11-25 | Merck & Co., Inc. | Piperazine derivatives for treatment of ad and related conditions |
CN103402516B (zh) | 2010-06-17 | 2018-01-30 | 富津世生物技术有限公司 | 用作抗病毒药物的化合物、组合物及使用方法 |
CN106045986B (zh) * | 2016-05-31 | 2019-12-06 | 广东工业大学 | 一种新型吩噻嗪衍生物及其制备方法与应用 |
CN106045987B (zh) * | 2016-06-21 | 2019-04-23 | 广东工业大学 | 一种具有多功能近红外荧光磁性纳米微粒及其制备和应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5740478A (en) * | 1980-08-22 | 1982-03-06 | Ono Pharmaceut Co Ltd | Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative |
JPH01147462A (ja) * | 1987-12-03 | 1989-06-09 | Mita Ind Co Ltd | 電荷発生材料およびその製法 |
JPH01147476A (ja) * | 1987-12-03 | 1989-06-09 | Mita Ind Co Ltd | 光導電性トナー |
US5143929A (en) * | 1991-05-09 | 1992-09-01 | Warner-Lambert Company | 2-substituted thiazolidinone, oxazolidinone, and imidazolidinone derivatives of fenamates as antiinflammatory agents |
ZA936492B (en) * | 1992-09-10 | 1995-03-02 | Lilly Co Eli | Compounds useful as hypoglycemic agents and for treating Alzheimer's disease. |
DE4318550A1 (de) * | 1993-06-04 | 1994-12-08 | Boehringer Mannheim Gmbh | Aryliden-4-oxo-2-thioxo-3- thiazolidincarbonsäuren, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
US6251928B1 (en) * | 1994-03-16 | 2001-06-26 | Eli Lilly And Company | Treatment of alzheimer's disease employing inhibitors of cathepsin D |
WO1997026919A2 (en) * | 1996-01-24 | 1997-07-31 | Warner-Lambert Company | Method of imaging amyloid deposits |
KR20010099623A (ko) * | 1998-08-21 | 2001-11-09 | 비로파마 인코포레이티드 | 바이러스 감염 및 관련 질병을 치료 또는 예방하는화합물, 조성물 및 방법 |
WO2000018747A1 (en) * | 1998-09-30 | 2000-04-06 | Roche Diagnostics Gmbh | Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders |
-
2000
- 2000-05-31 TR TR2001/03562T patent/TR200103562T2/xx unknown
- 2000-05-31 EP EP00938021A patent/EP1192143A1/en not_active Withdrawn
- 2000-05-31 JP JP2001503845A patent/JP2003502320A/ja active Pending
- 2000-05-31 BR BR0011441-3A patent/BR0011441A/pt not_active IP Right Cessation
- 2000-05-31 CA CA002374616A patent/CA2374616A1/en not_active Abandoned
- 2000-05-31 WO PCT/US2000/015069 patent/WO2000076987A1/en not_active Application Discontinuation
- 2000-05-31 MX MXPA01010490A patent/MXPA01010490A/es unknown
- 2000-05-31 AU AU53118/00A patent/AU5311800A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2374616A1 (en) | 2000-12-21 |
JP2003502320A (ja) | 2003-01-21 |
AU5311800A (en) | 2001-01-02 |
WO2000076987A1 (en) | 2000-12-21 |
MXPA01010490A (es) | 2005-05-27 |
TR200103562T2 (tr) | 2002-04-22 |
EP1192143A1 (en) | 2002-04-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: dismissal - article 86 of industrial property law |
Free format text: REFERENTE A 8O E 9O ANUIDADES. |
|
B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009. |