ATE213410T1 - Diclofenac/gamma-cyclodextrin klathrat komponente - Google Patents
Diclofenac/gamma-cyclodextrin klathrat komponenteInfo
- Publication number
- ATE213410T1 ATE213410T1 AT97919309T AT97919309T ATE213410T1 AT E213410 T1 ATE213410 T1 AT E213410T1 AT 97919309 T AT97919309 T AT 97919309T AT 97919309 T AT97919309 T AT 97919309T AT E213410 T1 ATE213410 T1 AT E213410T1
- Authority
- AT
- Austria
- Prior art keywords
- diclofenac
- pct
- gamma
- date
- cyclodextrin
- Prior art date
Links
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 title abstract 3
- 229960001259 diclofenac Drugs 0.000 title abstract 3
- 229920000858 Cyclodextrin Polymers 0.000 title abstract 2
- GDSRMADSINPKSL-HSEONFRVSA-N gamma-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO GDSRMADSINPKSL-HSEONFRVSA-N 0.000 title abstract 2
- 229940080345 gamma-cyclodextrin Drugs 0.000 title abstract 2
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 229940126701 oral medication Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9600758A HUP9600758A2 (en) | 1996-03-27 | 1996-03-27 | Diclofenac composition of diminished gastrointestinal irritation and enhanced biological resorption |
| PCT/EP1997/001595 WO1997035568A2 (en) | 1996-03-27 | 1997-03-27 | Diclofenac/gamma-cyclodextrin inclusion compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE213410T1 true ATE213410T1 (de) | 2002-03-15 |
Family
ID=89993834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97919309T ATE213410T1 (de) | 1996-03-27 | 1997-03-27 | Diclofenac/gamma-cyclodextrin klathrat komponente |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6071964A (de) |
| EP (1) | EP0893994B1 (de) |
| JP (1) | JP2000507258A (de) |
| CN (1) | CN1217658A (de) |
| AT (1) | ATE213410T1 (de) |
| AU (1) | AU713902B2 (de) |
| BR (1) | BR9708280A (de) |
| CA (1) | CA2250009A1 (de) |
| DE (1) | DE69710574D1 (de) |
| HU (1) | HUP9600758A2 (de) |
| PL (1) | PL329036A1 (de) |
| WO (1) | WO1997035568A2 (de) |
| ZA (1) | ZA972707B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2379854B (en) * | 2001-09-19 | 2006-04-19 | Walcom Animal Science | Dairy cow feed and the use thereof |
| AU2002366588A1 (en) * | 2001-12-13 | 2003-06-23 | Council Of Scientific And Industrial Research | Bioavailability enhancing activity of zingiber officinale linn and its extracts/fractions thereof |
| US20090215735A1 (en) * | 2002-02-25 | 2009-08-27 | Alcon, Inc. | Topical solution formulations containing a corticosteroid and a cyclodextrin |
| CN1232539C (zh) * | 2002-05-10 | 2005-12-21 | 刘云清 | 有机药物与倍他环糊精衍生物的配合物及其制备方法 |
| BRPI0709410A2 (pt) * | 2006-03-20 | 2011-07-12 | Javelin Pharmaceuticals Inc | composição farmacêutica e método para tratar um mamìfero necessitando de um agente analgésico, anti-inflamatório ou um antipirético |
| JP5823093B2 (ja) * | 2006-03-28 | 2015-11-25 | ジャヴェリン ファーマシューティカルズ インコーポレイテッド | 低投与量のジクロフェナク及びβ−シクロデキストリンの配合物 |
| JP2009196922A (ja) * | 2008-02-21 | 2009-09-03 | Glovia:Kk | 徐放性フェルラ酸製剤 |
| US20110009362A1 (en) * | 2008-02-27 | 2011-01-13 | Dr. Reddy's Laboratories Ltd. | Solubility-enhanced forms of aprepitant and pharmaceutical compositions thereof |
| EP2422818A3 (de) * | 2010-08-27 | 2013-01-16 | Tecnimede-Sociedade Tecnico-Medicinal, S.A. | Verfahren zur Herstellung eines Diclofenac-Cyclodextrin Konjugates |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5984821A (ja) * | 1982-11-04 | 1984-05-16 | Teikoku Chem Ind Corp Ltd | 徐溶化組成物 |
| IT1227626B (it) * | 1988-11-28 | 1991-04-23 | Vectorpharma Int | Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione |
| IT1241417B (it) * | 1990-03-06 | 1994-01-14 | Vectorpharma Int | Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione |
| IT1243342B (it) * | 1990-07-13 | 1994-06-10 | Farcon Ag | Composizioni farmaceutiche orali liquide ad attivita' antiinfiammatoria |
| IT1247529B (it) * | 1991-04-24 | 1994-12-17 | Poli Ind Chimica Spa | Composizioni farmaceutiche in forma di schiuma per somministrazione intravaginale, cutanea e orale |
| EP1004318A3 (de) * | 1991-06-21 | 2002-08-07 | Takeda Chemical Industries, Ltd. | Zyklodextrin-zusammensetzung |
| DE4207922A1 (de) * | 1992-03-13 | 1993-09-23 | Pharmatech Gmbh | Wasserloesliche einschlussverbindungen und verfahren zu deren herstellung |
| NZ267417A (en) * | 1993-06-08 | 1997-02-24 | Ciba Geigy Ag | An inclusion compound of diclofenac and gamma-cyclodextrin and compressed dosage forms thereof |
| IT1264696B1 (it) * | 1993-07-09 | 1996-10-04 | Applied Pharma Res | Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata |
| IL111184A (en) * | 1993-10-08 | 2000-08-13 | Farmarc Nederland B V Of Cito | Crystalline inclusion complex of diclofenac with unsubstituted beta-cyclodextrin |
| ZA949182B (en) * | 1993-12-02 | 1995-07-26 | South African Druggists Ltd | Pharmaceutical composition |
-
1996
- 1996-03-27 HU HU9600758A patent/HUP9600758A2/hu unknown
-
1997
- 1997-03-27 AT AT97919309T patent/ATE213410T1/de not_active IP Right Cessation
- 1997-03-27 US US09/155,298 patent/US6071964A/en not_active Expired - Fee Related
- 1997-03-27 DE DE69710574T patent/DE69710574D1/de not_active Expired - Lifetime
- 1997-03-27 BR BR9708280A patent/BR9708280A/pt unknown
- 1997-03-27 PL PL97329036A patent/PL329036A1/xx unknown
- 1997-03-27 CN CN97194134A patent/CN1217658A/zh active Pending
- 1997-03-27 WO PCT/EP1997/001595 patent/WO1997035568A2/en active IP Right Grant
- 1997-03-27 ZA ZA9702707A patent/ZA972707B/xx unknown
- 1997-03-27 CA CA002250009A patent/CA2250009A1/en not_active Abandoned
- 1997-03-27 AU AU23829/97A patent/AU713902B2/en not_active Ceased
- 1997-03-27 JP JP9534053A patent/JP2000507258A/ja active Pending
- 1997-03-27 EP EP97919309A patent/EP0893994B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997035568A3 (en) | 1997-12-04 |
| EP0893994A2 (de) | 1999-02-03 |
| WO1997035568A2 (en) | 1997-10-02 |
| CA2250009A1 (en) | 1997-10-02 |
| HU9600758D0 (en) | 1996-05-28 |
| DE69710574D1 (de) | 2002-03-28 |
| JP2000507258A (ja) | 2000-06-13 |
| AU2382997A (en) | 1997-10-17 |
| PL329036A1 (en) | 1999-03-01 |
| BR9708280A (pt) | 1999-08-03 |
| US6071964A (en) | 2000-06-06 |
| HUP9600758A2 (en) | 1998-03-02 |
| EP0893994B1 (de) | 2002-02-20 |
| AU713902B2 (en) | 1999-12-16 |
| CN1217658A (zh) | 1999-05-26 |
| ZA972707B (en) | 1997-10-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TR200200579T2 (tr) | Amino-tirazolpiridin türevleri. | |
| ATE260646T1 (de) | Schnell zerfallende orale dosierungsform | |
| ATE202337T1 (de) | Cyclopropylalkansäurederivate | |
| BG105459A (en) | Pharmaceutical moxifloxacin preparation | |
| SE9401728D0 (sv) | New compounds II | |
| BG106293A (en) | Method of inhibiting amyloid protein aggregation and imaging amyloid deposits | |
| NZ296573A (en) | A free flowing powder comprises lamotrigine (or salt thereof), lactose, starch, crystalline cellulose, and polyvinylpyrrolidone | |
| DE69710574D1 (de) | Diclofenac/gamma-cyclodextrin klathrat komponente | |
| HUP0500842A2 (hu) | Dronedaront tartalmazó gyógyászati készítmény parenterális adagolásra | |
| DK0866711T3 (da) | Anvendelse af 6-methyl-5-oxo-3-thiomorpholinylcarbonyl-L-histidyl-L-prolinamid til fremstilling af et farmaceutisk præparat til modvirkning af sövnapnö | |
| NO20031410L (no) | Anvendelse av distamycinderivater for fremstilling av medikamenter | |
| DE69330601T2 (de) | Serotoninergische ergolin derivate | |
| AR002191A1 (es) | Composicion farmaceutica oral de compuestos de piperidinoalcanol en forma de solucion, procedimiento para su preparacion | |
| TR200103561T2 (tr) | Rodanin türevleri ve amiloidlerin önlenmesi ve görüntülenmesinde kullanımları | |
| NO20004545L (no) | FremgangsmÕte for fremstilling av (R)-<alfa>-(2,3- dimetoksyfenyl)-1-[2-(4-fluorofenyl)etyl]-4-piperidinmetanol | |
| BG106151A (en) | Pharmaceutical complex | |
| HUP9702448A2 (hu) | Indolkarbonsavat tartalmazó, parenterálisan adható gyógyászati készítmény | |
| NO941084D0 (no) | Neuroleptiske 2-substituerte perhydro-1-H-pyrido[1,2-aÅpyraziner | |
| PT855398E (pt) | Derivados sasquiterpeno tendo actividade antiviral | |
| DE69910787D1 (de) | Neuartige, pharmazeutisch aktive verbindung | |
| DE69318715D1 (de) | Pharmakologisch aktive alpha-(tertiär-aminoethyl)-phenylmethanol-derivate | |
| SE9404438D0 (sv) | New process | |
| SE9602262D0 (sv) | New use of derivatives of cystine | |
| EA200401617A1 (ru) | Комбинация nmda-антагониста и ингибиторов ацетилхолинэстеразы для лечения болезни альцгеймера | |
| BR9712628A (pt) | Derivados de 8(9)-deidroestradiol |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |