TR200100731T2 - Geçici ve aralıklı kontrol sağlayan, oral yoldan kontrollü ilaç verme sistemi - Google Patents

Geçici ve aralıklı kontrol sağlayan, oral yoldan kontrollü ilaç verme sistemi

Info

Publication number
TR200100731T2
TR200100731T2 TR2001/00731T TR200100731T TR200100731T2 TR 200100731 T2 TR200100731 T2 TR 200100731T2 TR 2001/00731 T TR2001/00731 T TR 2001/00731T TR 200100731 T TR200100731 T TR 200100731T TR 200100731 T2 TR200100731 T2 TR 200100731T2
Authority
TR
Turkey
Prior art keywords
drug
agent
intermittent control
temporary
pharmaceutical composition
Prior art date
Application number
TR2001/00731T
Other languages
English (en)
Inventor
Talwar Naresh
Sen Himadri
H. Staniforth John
Original Assignee
Ranbaxy Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/152,932 external-priority patent/US6261601B1/en
Application filed by Ranbaxy Laboratories Limited filed Critical Ranbaxy Laboratories Limited
Publication of TR200100731T2 publication Critical patent/TR200100731T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Cardiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Physiology (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Tabletler veya kapsüller halinde bir farmasötik kompozisyon, etkili terapötik sonuçlar için bir hastaya verilen ilacin geçici ve aralikli kontrolünün bir kombinasyonunu saglar. Farmasötik kompozisyon,bir ilaç, bir gaz üretici bilesen, bir kabartma maddesi, bir viskolize edici madde ve istege bagli olarak bir jel olusturma polimeri içerir. Kabartma maddesi, süper ayristiricilar olarak bilinen bir bilesik sinifina aittir. (örn. çapraz bagli polivinilpirolidon veya sodyum karboksimetilselüloz). Viskolize edici madde baslangiçta ve jel olusturucu polimer daha sonra, gazi hapseden hidre edilmis bir jel matris olusturur ve tabletin veya kapsülün yüzmesine neden olur, böylece midede veya ince bagirsagi üst kisminda tutulur (aralikli kontrol). Ayni zamanda hidre edilen jel matris, ilaç için ivicaçli bir yayilma yolu yaratir ve ilacin sürekli birakilmasini saglar (geçici kontrol). Tercih edilen günde bir kerelik siprofloksasin formülasyonu, %69.9 siprofloksasin baz, %0.34 sodyum alginat,
TR2001/00731T 1998-09-14 1999-01-19 Geçici ve aralıklı kontrol sağlayan, oral yoldan kontrollü ilaç verme sistemi TR200100731T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/152,932 US6261601B1 (en) 1997-09-19 1998-09-14 Orally administered controlled drug delivery system providing temporal and spatial control

Publications (1)

Publication Number Publication Date
TR200100731T2 true TR200100731T2 (tr) 2001-06-21

Family

ID=22545063

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/00731T TR200100731T2 (tr) 1998-09-14 1999-01-19 Geçici ve aralıklı kontrol sağlayan, oral yoldan kontrollü ilaç verme sistemi

Country Status (41)

Country Link
EP (2) EP1281397A1 (tr)
JP (1) JP2002524494A (tr)
CN (1) CN1186013C (tr)
AP (1) AP1659A (tr)
AR (1) AR022672A1 (tr)
AT (1) ATE245414T1 (tr)
AU (1) AU758324B2 (tr)
BG (1) BG105339A (tr)
BR (1) BR9913696A (tr)
CA (1) CA2343760A1 (tr)
CO (1) CO5130022A1 (tr)
CU (1) CU23040A3 (tr)
CZ (1) CZ2001901A3 (tr)
DE (1) DE69909801T2 (tr)
DK (1) DK1107741T3 (tr)
EA (2) EA004443B1 (tr)
EE (1) EE200100153A (tr)
ES (1) ES2204098T3 (tr)
GE (1) GEP20043216B (tr)
HK (1) HK1037967A1 (tr)
HR (1) HRP20010187B1 (tr)
HU (1) HUP0103632A3 (tr)
ID (1) ID29843A (tr)
IL (1) IL141977A0 (tr)
IS (1) IS5885A (tr)
MX (1) MXPA01002634A (tr)
MY (1) MY127952A (tr)
NO (1) NO20011276L (tr)
NZ (2) NZ510487A (tr)
OA (1) OA11652A (tr)
PE (1) PE20001058A1 (tr)
PL (1) PL346798A1 (tr)
PT (1) PT1107741E (tr)
SI (1) SI1107741T1 (tr)
SK (1) SK285478B6 (tr)
SV (1) SV1999000152A (tr)
TR (1) TR200100731T2 (tr)
UA (1) UA73287C2 (tr)
UY (1) UY25710A1 (tr)
WO (1) WO2000015198A1 (tr)
ZA (1) ZA995839B (tr)

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AU2006202275A1 (en) * 2000-06-26 2006-06-22 Bayer Healthcare Ag Sustained-release preparations of quinolone antibiotics and method for preparation thereof
DE10031043A1 (de) 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
US6861071B2 (en) * 2000-08-08 2005-03-01 Daiichi Pharmaceutical Co., Ltd. Highly absorptive solid preparation
IN192748B (tr) * 2000-08-29 2004-05-15 Ranbaxy Lab Ltd
CA2431205C (en) 2000-12-05 2005-08-23 Alexander Macgregor Hydrostatic delivery system for controlled delivery of agent
MXPA03012041A (es) 2001-07-04 2004-03-26 Sun Pharmaceutical Ind Ltd Sistema de administracion controlada de farmacos de retencion gastrica.
PL368327A1 (en) * 2001-08-16 2005-03-21 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Expandable gastric retention device
US6673369B2 (en) * 2001-08-29 2004-01-06 Ranbaxy Laboratories Limited Controlled release formulation
AU2002351798A1 (en) * 2001-10-29 2003-05-12 Labopharm Inc. Methods and dosage forms for improving the bioavailability of therapeutic agents
RU2322263C2 (ru) * 2001-11-13 2008-04-20 Астеллас Фарма, Инк. Система продолжительного высвобождения растворимого лекарственного средства
PT1461017E (pt) 2001-11-19 2006-07-31 Lupin Ltd Composicao farmaceutica para a libertacao controlada de um antibiotico beta-lactamico
DE60219965T2 (de) * 2002-04-23 2008-01-17 Lupin Ltd., Mumbai Lang wirkende zusammensetzungen enthaltend zidovudine und/oder lamivudine
WO2005018613A1 (de) * 2003-08-26 2005-03-03 Mandapro Ag Pellets für die orale applikation von pharmazeutischen wirkstoffen
DE102004042139B4 (de) * 2004-08-31 2009-06-10 Aristocon Verwaltungs- Gmbh Perorale Darreichungsformen zur Erzielung eines Retardierungseffektes nach der Arzneimitteleinnahme mit einer Mahlzeit
GB0501810D0 (en) * 2005-01-28 2005-03-09 Pharmakodex Ltd Chemotherapeutic formulations
US20090099154A1 (en) * 2005-06-29 2009-04-16 Panacea Biotec Ltd. Pharmaceutical Sustained Release Compositions and Processes Thereof
ATE396710T1 (de) * 2005-07-19 2008-06-15 Ethypharm Sa Gastroretentive zusammensetzungen und verfahren zur herstellung
GB0515492D0 (en) * 2005-07-28 2005-08-31 Reckitt Benckiser Healthcare Improvements in or relating to compositions,articles and methods
KR20080076382A (ko) * 2007-02-15 2008-08-20 (주)아모레퍼시픽 실로스타졸의 제어방출 제제 및 그 제조방법
WO2010020098A1 (zh) 2008-08-18 2010-02-25 北京天衡药物研究院 胃滞留药物释出系统及其制备方法和用途
ZA200903854B (en) * 2008-06-19 2011-02-23 Univ Of The Witwatesrand Johannesburg A gastroretentive pharmaceutical dosage form
WO2011125075A2 (en) 2010-04-08 2011-10-13 Fdc Limited A novel gastroretentive delivery of macrolide
EP2415460A1 (de) * 2010-08-03 2012-02-08 ratiopharm GmbH Orale Darreichungsform von Pregabalin
TWI705814B (zh) * 2014-06-20 2020-10-01 美商梅琳塔有限責任公司 醫藥組成物及其用途
US11504324B2 (en) 2014-11-19 2022-11-22 DuPont Nutrition USA, Inc. Nanosuspension formulation
US10987311B2 (en) 2017-06-16 2021-04-27 Kashiv Specialty Pharmaceuticals, Llc Extended release compositions comprising pyridostigmine
CN110996922A (zh) 2017-06-16 2020-04-10 卡希夫生物科学有限责任公司 用于持续药物递送的胃滞留剂型
US10588863B2 (en) 2017-06-16 2020-03-17 Kashiv Biosciences, Llc Extended release compositions comprising pyridostigmine
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WO2020006278A1 (en) 2018-06-27 2020-01-02 Kashiv Biosciences, Llc Self-regulating osmotic gastroretentive drug delivery systems
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CN111116794A (zh) * 2019-12-20 2020-05-08 蚌埠市鑫晟新材料科技有限公司 一种中性造纸用聚合材料的制备方法
CN115715765A (zh) * 2021-08-24 2023-02-28 江苏万邦生化医药集团有限责任公司 一种悬浮片剂
CN113768898A (zh) * 2021-09-14 2021-12-10 江苏万邦生化医药集团有限责任公司 悬浮的胶囊片

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Also Published As

Publication number Publication date
MXPA01002634A (es) 2002-06-04
EE200100153A (et) 2002-06-17
EP1281397A1 (en) 2003-02-05
NZ510487A (en) 2003-04-29
HK1037967A1 (en) 2002-03-01
EA200300847A1 (ru) 2003-12-25
DE69909801D1 (de) 2003-08-28
AU758324B2 (en) 2003-03-20
PT1107741E (pt) 2003-12-31
ES2204098T3 (es) 2004-04-16
NZ523747A (en) 2004-04-30
PL346798A1 (en) 2002-02-25
CA2343760A1 (en) 2000-03-23
ZA995839B (en) 2000-03-28
CN1186013C (zh) 2005-01-26
HRP20010187B1 (en) 2004-04-30
PE20001058A1 (es) 2000-10-05
DE69909801T2 (de) 2004-06-03
CO5130022A1 (es) 2002-02-27
IL141977A0 (en) 2002-03-10
EA004443B1 (ru) 2004-04-29
CU23040A3 (es) 2005-04-14
UY25710A1 (es) 2000-03-31
AP2001002098A0 (en) 2001-03-31
EP1107741A1 (en) 2001-06-20
ATE245414T1 (de) 2003-08-15
EP1107741B1 (en) 2003-07-23
OA11652A (en) 2004-12-08
SI1107741T1 (en) 2004-02-29
HUP0103632A2 (hu) 2002-02-28
MY127952A (en) 2007-01-31
CN1325299A (zh) 2001-12-05
GEP20043216B (en) 2004-04-26
SK285478B6 (sk) 2007-02-01
AP1659A (en) 2006-09-06
WO2000015198A1 (en) 2000-03-23
EA200100346A1 (ru) 2001-10-22
SK3472001A3 (en) 2001-10-08
JP2002524494A (ja) 2002-08-06
UA73287C2 (en) 2005-07-15
NO20011276D0 (no) 2001-03-13
AU1779499A (en) 2000-04-03
HRP20010187A2 (en) 2002-04-30
BR9913696A (pt) 2001-10-09
DK1107741T3 (da) 2003-11-17
AR022672A1 (es) 2002-09-04
CZ2001901A3 (cs) 2001-08-15
NO20011276L (no) 2001-05-10
ID29843A (id) 2001-10-18
BG105339A (en) 2001-11-30
EA005767B1 (ru) 2005-06-30
SV1999000152A (es) 2000-07-03
IS5885A (is) 2001-03-12
HUP0103632A3 (en) 2005-06-28

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