SV1999000152A - Sistema de entrega controlado de droga administrado oralmente, que provee control temporal y espacial - Google Patents

Sistema de entrega controlado de droga administrado oralmente, que provee control temporal y espacial

Info

Publication number
SV1999000152A
SV1999000152A SV1999000152A SV1999000152A SV1999000152A SV 1999000152 A SV1999000152 A SV 1999000152A SV 1999000152 A SV1999000152 A SV 1999000152A SV 1999000152 A SV1999000152 A SV 1999000152A SV 1999000152 A SV1999000152 A SV 1999000152A
Authority
SV
El Salvador
Prior art keywords
guai
space control
drugs
drug
agent
Prior art date
Application number
SV1999000152A
Other languages
English (en)
Inventor
Naresh Talwar
Himadri Sen
John N Staniforth
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/152,932 external-priority patent/US6261601B1/en
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of SV1999000152A publication Critical patent/SV1999000152A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Cardiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Physiology (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UNA COMPOSICION FARMACEUTICA EN FORMA DE TABLETAS O CAPSULAS PROVEE UNA COMBINACION DE CONTROL TEMPORAL Y ESPACIAL DE LIBERACION DE UNA DROGA A UN PACIENTE PARA RESULTADOS TERAPEUTICOS EFECTIVOS. LA COMPOSICION FARMACEUTICA COMPRENDE UNA DROGA, UN COMPONENTE GENERADOR DE GAS, UN AGENTE DILATADOR, UN AGENTE VISCOSO, Y OPCIONALMENTE UN POLIMERO FORMADOR DE GEL. EL AGENTE DILATADOR PERTENECE A UN GRUPO DE COMPUESTOS CONOCIDOS COMO SUPERDESINTEGRADORES (POR EJEMPLO: LA POLIVINILPIRROLIDONA DE ENLACE CRUZADO O LA CARBOXIMETILCELULOSA DE SODIO) INICIALMENTE EL AGENTE VISCOSO Y LUEGO EL POLIMERO FORMADOR DE GEL, FORMAN UNA MATRIZ DE GEL HIDRATADA QUE OCLUYE EL GAS, CAUSANDO QUE LA TABLETA O CAPSULA FLOTEN PARA SER RETENIDAS EN EL ESTOMAGO O EN LA PARTE ALTA DEL INTESTINO DELGADO (CONTROL ESPACIAL). AL MISMO TIEMPO LA MATRIZ DEL GEL HIDRATADO CREA UN CAMINO DE DIFUSION TORTUOSO PARA LA DROGA, LO QUE RESULTA EN UNA LIBERACION SOSTENIDA DE LA DROGA(CONTROL TEMPORAL). UNA FORMULACION, PREFERIDA, DE CIPROFLOXACIN ADMINISTRADA UNA SOLA VEZ AL DIA COMPRENDE 69.9% DE BASE DE CIPROFLOXACIN , 0.34% DE ALGINATO DE SODIO, 1.03% DE GOMA JANTICA, 13.7% DE BICARBONATO DE SODIO, 12.1% DE POLIVINILPIRROLIDONA DE ENLAZE CRUZADO, Y OPCIONALMENTE OTROS EXCIPIENTES FARMACEUTICOS, LA FORMULACION ESTA EN FORMA DE TABLETAS RECUBIERTAS O NO, O EN CAPSULAS
SV1999000152A 1998-09-14 1999-09-13 Sistema de entrega controlado de droga administrado oralmente, que provee control temporal y espacial SV1999000152A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/152,932 US6261601B1 (en) 1997-09-19 1998-09-14 Orally administered controlled drug delivery system providing temporal and spatial control

Publications (1)

Publication Number Publication Date
SV1999000152A true SV1999000152A (es) 2000-07-03

Family

ID=22545063

Family Applications (1)

Application Number Title Priority Date Filing Date
SV1999000152A SV1999000152A (es) 1998-09-14 1999-09-13 Sistema de entrega controlado de droga administrado oralmente, que provee control temporal y espacial

Country Status (41)

Country Link
EP (2) EP1281397A1 (es)
JP (1) JP2002524494A (es)
CN (1) CN1186013C (es)
AP (1) AP1659A (es)
AR (1) AR022672A1 (es)
AT (1) ATE245414T1 (es)
AU (1) AU758324B2 (es)
BG (1) BG105339A (es)
BR (1) BR9913696A (es)
CA (1) CA2343760A1 (es)
CO (1) CO5130022A1 (es)
CU (1) CU23040A3 (es)
CZ (1) CZ2001901A3 (es)
DE (1) DE69909801T2 (es)
DK (1) DK1107741T3 (es)
EA (2) EA004443B1 (es)
EE (1) EE200100153A (es)
ES (1) ES2204098T3 (es)
GE (1) GEP20043216B (es)
HK (1) HK1037967A1 (es)
HR (1) HRP20010187B1 (es)
HU (1) HUP0103632A3 (es)
ID (1) ID29843A (es)
IL (1) IL141977A0 (es)
IS (1) IS5885A (es)
MX (1) MXPA01002634A (es)
MY (1) MY127952A (es)
NO (1) NO20011276L (es)
NZ (2) NZ510487A (es)
OA (1) OA11652A (es)
PE (1) PE20001058A1 (es)
PL (1) PL346798A1 (es)
PT (1) PT1107741E (es)
SI (1) SI1107741T1 (es)
SK (1) SK285478B6 (es)
SV (1) SV1999000152A (es)
TR (1) TR200100731T2 (es)
UA (1) UA73287C2 (es)
UY (1) UY25710A1 (es)
WO (1) WO2000015198A1 (es)
ZA (1) ZA995839B (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030009374A (ko) * 2000-03-03 2003-01-29 랜박시 래보러터리스 리미티드 시프로플록사신의 1일 1회 투여를 위한 경구 투여용제어된 전달 시스템
AU2006202275A1 (en) * 2000-06-26 2006-06-22 Bayer Healthcare Ag Sustained-release preparations of quinolone antibiotics and method for preparation thereof
DE10031043A1 (de) 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
US6861071B2 (en) * 2000-08-08 2005-03-01 Daiichi Pharmaceutical Co., Ltd. Highly absorptive solid preparation
IN192748B (es) * 2000-08-29 2004-05-15 Ranbaxy Lab Ltd
CA2431205C (en) 2000-12-05 2005-08-23 Alexander Macgregor Hydrostatic delivery system for controlled delivery of agent
MXPA03012041A (es) 2001-07-04 2004-03-26 Sun Pharmaceutical Ind Ltd Sistema de administracion controlada de farmacos de retencion gastrica.
PL368327A1 (en) * 2001-08-16 2005-03-21 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Expandable gastric retention device
US6673369B2 (en) * 2001-08-29 2004-01-06 Ranbaxy Laboratories Limited Controlled release formulation
AU2002351798A1 (en) * 2001-10-29 2003-05-12 Labopharm Inc. Methods and dosage forms for improving the bioavailability of therapeutic agents
RU2322263C2 (ru) * 2001-11-13 2008-04-20 Астеллас Фарма, Инк. Система продолжительного высвобождения растворимого лекарственного средства
PT1461017E (pt) 2001-11-19 2006-07-31 Lupin Ltd Composicao farmaceutica para a libertacao controlada de um antibiotico beta-lactamico
DE60219965T2 (de) * 2002-04-23 2008-01-17 Lupin Ltd., Mumbai Lang wirkende zusammensetzungen enthaltend zidovudine und/oder lamivudine
WO2005018613A1 (de) * 2003-08-26 2005-03-03 Mandapro Ag Pellets für die orale applikation von pharmazeutischen wirkstoffen
DE102004042139B4 (de) * 2004-08-31 2009-06-10 Aristocon Verwaltungs- Gmbh Perorale Darreichungsformen zur Erzielung eines Retardierungseffektes nach der Arzneimitteleinnahme mit einer Mahlzeit
GB0501810D0 (en) * 2005-01-28 2005-03-09 Pharmakodex Ltd Chemotherapeutic formulations
US20090099154A1 (en) * 2005-06-29 2009-04-16 Panacea Biotec Ltd. Pharmaceutical Sustained Release Compositions and Processes Thereof
ATE396710T1 (de) * 2005-07-19 2008-06-15 Ethypharm Sa Gastroretentive zusammensetzungen und verfahren zur herstellung
GB0515492D0 (en) * 2005-07-28 2005-08-31 Reckitt Benckiser Healthcare Improvements in or relating to compositions,articles and methods
KR20080076382A (ko) * 2007-02-15 2008-08-20 (주)아모레퍼시픽 실로스타졸의 제어방출 제제 및 그 제조방법
WO2010020098A1 (zh) 2008-08-18 2010-02-25 北京天衡药物研究院 胃滞留药物释出系统及其制备方法和用途
ZA200903854B (en) * 2008-06-19 2011-02-23 Univ Of The Witwatesrand Johannesburg A gastroretentive pharmaceutical dosage form
WO2011125075A2 (en) 2010-04-08 2011-10-13 Fdc Limited A novel gastroretentive delivery of macrolide
EP2415460A1 (de) * 2010-08-03 2012-02-08 ratiopharm GmbH Orale Darreichungsform von Pregabalin
TWI705814B (zh) * 2014-06-20 2020-10-01 美商梅琳塔有限責任公司 醫藥組成物及其用途
US11504324B2 (en) 2014-11-19 2022-11-22 DuPont Nutrition USA, Inc. Nanosuspension formulation
US10987311B2 (en) 2017-06-16 2021-04-27 Kashiv Specialty Pharmaceuticals, Llc Extended release compositions comprising pyridostigmine
CN110996922A (zh) 2017-06-16 2020-04-10 卡希夫生物科学有限责任公司 用于持续药物递送的胃滞留剂型
US10588863B2 (en) 2017-06-16 2020-03-17 Kashiv Biosciences, Llc Extended release compositions comprising pyridostigmine
EP4056172A1 (en) 2018-06-18 2022-09-14 Amneal Complex Products Research LLC Extended release compositions comprising pyridostigmine
WO2020006278A1 (en) 2018-06-27 2020-01-02 Kashiv Biosciences, Llc Self-regulating osmotic gastroretentive drug delivery systems
CN110448535A (zh) * 2019-09-04 2019-11-15 湖南宇山玉月农业科技有限公司 一种裂褶菌素胃漂浮片
CN111116794A (zh) * 2019-12-20 2020-05-08 蚌埠市鑫晟新材料科技有限公司 一种中性造纸用聚合材料的制备方法
CN115715765A (zh) * 2021-08-24 2023-02-28 江苏万邦生化医药集团有限责任公司 一种悬浮片剂
CN113768898A (zh) * 2021-09-14 2021-12-10 江苏万邦生化医药集团有限责任公司 悬浮的胶囊片

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0798742B2 (ja) * 1986-07-03 1995-10-25 ゼリア新薬工業株式会社 徐放性製剤組成物
US5096714A (en) * 1988-06-28 1992-03-17 Hauser-Kuhrts, Inc. Prolonged release drug tablet formulations
JPH0624959A (ja) * 1991-10-04 1994-02-01 Bayer Yakuhin Kk 胃内浮遊型薬物徐放性固形製剤

Also Published As

Publication number Publication date
MXPA01002634A (es) 2002-06-04
EE200100153A (et) 2002-06-17
EP1281397A1 (en) 2003-02-05
NZ510487A (en) 2003-04-29
HK1037967A1 (en) 2002-03-01
EA200300847A1 (ru) 2003-12-25
TR200100731T2 (tr) 2001-06-21
DE69909801D1 (de) 2003-08-28
AU758324B2 (en) 2003-03-20
PT1107741E (pt) 2003-12-31
ES2204098T3 (es) 2004-04-16
NZ523747A (en) 2004-04-30
PL346798A1 (en) 2002-02-25
CA2343760A1 (en) 2000-03-23
ZA995839B (en) 2000-03-28
CN1186013C (zh) 2005-01-26
HRP20010187B1 (en) 2004-04-30
PE20001058A1 (es) 2000-10-05
DE69909801T2 (de) 2004-06-03
CO5130022A1 (es) 2002-02-27
IL141977A0 (en) 2002-03-10
EA004443B1 (ru) 2004-04-29
CU23040A3 (es) 2005-04-14
UY25710A1 (es) 2000-03-31
AP2001002098A0 (en) 2001-03-31
EP1107741A1 (en) 2001-06-20
ATE245414T1 (de) 2003-08-15
EP1107741B1 (en) 2003-07-23
OA11652A (en) 2004-12-08
SI1107741T1 (en) 2004-02-29
HUP0103632A2 (hu) 2002-02-28
MY127952A (en) 2007-01-31
CN1325299A (zh) 2001-12-05
GEP20043216B (en) 2004-04-26
SK285478B6 (sk) 2007-02-01
AP1659A (en) 2006-09-06
WO2000015198A1 (en) 2000-03-23
EA200100346A1 (ru) 2001-10-22
SK3472001A3 (en) 2001-10-08
JP2002524494A (ja) 2002-08-06
UA73287C2 (en) 2005-07-15
NO20011276D0 (no) 2001-03-13
AU1779499A (en) 2000-04-03
HRP20010187A2 (en) 2002-04-30
BR9913696A (pt) 2001-10-09
DK1107741T3 (da) 2003-11-17
AR022672A1 (es) 2002-09-04
CZ2001901A3 (cs) 2001-08-15
NO20011276L (no) 2001-05-10
ID29843A (id) 2001-10-18
BG105339A (en) 2001-11-30
EA005767B1 (ru) 2005-06-30
IS5885A (is) 2001-03-12
HUP0103632A3 (en) 2005-06-28

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