TR200002037T2 - E-2-[4-(4-Kloro-1,2-difenil-but-1-enil) fenoksi]etanol ve onun farmasötik kompozisyonları. - Google Patents

E-2-[4-(4-Kloro-1,2-difenil-but-1-enil) fenoksi]etanol ve onun farmasötik kompozisyonları.

Info

Publication number
TR200002037T2
TR200002037T2 TR2000/02037T TR200002037T TR200002037T2 TR 200002037 T2 TR200002037 T2 TR 200002037T2 TR 2000/02037 T TR2000/02037 T TR 2000/02037T TR 200002037 T TR200002037 T TR 200002037T TR 200002037 T2 TR200002037 T2 TR 200002037T2
Authority
TR
Turkey
Prior art keywords
enyl
phenoxy
diphenyl
chloro
ethanol
Prior art date
Application number
TR2000/02037T
Other languages
English (en)
Inventor
S�dervall Marja-Liisa
Kalapudas Arja
Viitanen Antti
M�ntyl� Eero
Original Assignee
Orion Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corporation filed Critical Orion Corporation
Publication of TR200002037T2 publication Critical patent/TR200002037T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Mevcut bulus, serum kolesterolünü düsürücü özelliklere sahip olan E-2-[4-(4-kloro-1,2-difenil-but-1-enil)fenoksi]etanol ve onun farmasötik kompozisyonlari ile ilgilidir. Ayrica serum kolesterolünü düsürücü bir yöntem ve atherosklerozun önlenmesi veya tedavisi ile ilgili bir yöntem de açiklanmistir.
TR2000/02037T 1998-02-19 1999-02-19 E-2-[4-(4-Kloro-1,2-difenil-but-1-enil) fenoksi]etanol ve onun farmasötik kompozisyonları. TR200002037T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9803521.5A GB9803521D0 (en) 1998-02-19 1998-02-19 New compounds and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
TR200002037T2 true TR200002037T2 (tr) 2001-02-21

Family

ID=10827263

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02037T TR200002037T2 (tr) 1998-02-19 1999-02-19 E-2-[4-(4-Kloro-1,2-difenil-but-1-enil) fenoksi]etanol ve onun farmasötik kompozisyonları.

Country Status (33)

Country Link
US (1) US6395785B1 (tr)
EP (1) EP1056701B1 (tr)
JP (1) JP2002503713A (tr)
KR (1) KR100755918B1 (tr)
CN (1) CN1161314C (tr)
AR (1) AR014961A1 (tr)
AT (1) ATE252531T1 (tr)
AU (1) AU755798B2 (tr)
BG (1) BG64471B1 (tr)
BR (1) BR9907688A (tr)
CA (1) CA2321122C (tr)
CZ (1) CZ294315B6 (tr)
DE (1) DE69912247T2 (tr)
DK (1) DK1056701T3 (tr)
EA (1) EA002919B1 (tr)
EE (1) EE04233B1 (tr)
ES (1) ES2211038T3 (tr)
GB (1) GB9803521D0 (tr)
GE (1) GEP20022794B (tr)
HR (1) HRP20000545A2 (tr)
HU (1) HUP0101354A3 (tr)
ID (1) ID26857A (tr)
IL (1) IL137214A (tr)
NO (1) NO325595B1 (tr)
NZ (1) NZ505637A (tr)
PL (1) PL193315B1 (tr)
PT (1) PT1056701E (tr)
RS (1) RS49660B (tr)
SK (1) SK285940B6 (tr)
TR (1) TR200002037T2 (tr)
UA (1) UA57132C2 (tr)
WO (1) WO1999042427A1 (tr)
ZA (1) ZA991232B (tr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1705169A3 (en) * 1999-11-16 2006-11-15 Hormos Medical Ltd. Triphenylalkene derivatives and their use as selective estrogen receptor modulators
TW593256B (en) * 1999-11-16 2004-06-21 Hormos Medical Oy Ltd Triphenylalkene derivatives and their use as selective estrogen receptor modulators
US20040248989A1 (en) 2003-06-05 2004-12-09 Risto Santti Method for the treatment or prevention of lower urinary tract symptoms
KR101505884B1 (ko) 2006-05-22 2015-03-25 호르모스 메디칼 리미티드 만성 비세균성 전립선염 치료용 선택적 에스트로겐 수용체 조절제 또는 아로마타아제 저해제
CN101636372B (zh) 2007-02-14 2013-03-27 霍尔莫斯医疗有限公司 有治疗价值的三苯基丁烯衍生物的制备方法
WO2008099060A2 (en) 2007-02-14 2008-08-21 Hormos Medical Ltd Methods for the preparation of fispemifene from ospemifene
DK2526080T3 (da) 2010-01-19 2014-04-28 Cambrex Karlskoga Ab Nye fremgangsmåder til fremstilling af benzophenonderivater
US20150321983A1 (en) * 2012-10-19 2015-11-12 Fermion Oy A process for the preparation of ospemifene
WO2014060639A1 (en) 2012-10-19 2014-04-24 Fermion Oy A process for the preparation of ospemifene
CN104030896A (zh) * 2013-03-07 2014-09-10 天津药物研究院 一种简易去除欧司哌米芬特异杂质的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2126576B (en) 1982-06-25 1985-06-19 Farmos Group Limited Alkane and alkene derivatives
GB9418067D0 (en) 1994-09-07 1994-10-26 Orion Yhtymae Oy Triphenylethylenes for the prevention and treatment of osteoporosis
GB9604577D0 (en) * 1996-03-04 1996-05-01 Orion Yhtymae Oy Serum cholesterol lowering agent

Also Published As

Publication number Publication date
GEP20022794B (en) 2002-09-25
US6395785B1 (en) 2002-05-28
EP1056701B1 (en) 2003-10-22
CN1161314C (zh) 2004-08-11
KR20010040985A (ko) 2001-05-15
ATE252531T1 (de) 2003-11-15
CZ294315B6 (cs) 2004-11-10
SK285940B6 (sk) 2007-11-02
HRP20000545A2 (en) 2001-02-28
DE69912247D1 (de) 2003-11-27
ES2211038T3 (es) 2004-07-01
NZ505637A (en) 2002-10-25
DE69912247T2 (de) 2004-07-29
RS49660B (sr) 2007-09-21
NO325595B1 (no) 2008-06-23
IL137214A (en) 2005-05-17
EE04233B1 (et) 2004-02-16
PT1056701E (pt) 2004-03-31
CA2321122C (en) 2008-02-12
BG64471B1 (bg) 2005-04-30
PL342445A1 (en) 2001-06-04
AU755798B2 (en) 2002-12-19
NO20003987D0 (no) 2000-08-07
BR9907688A (pt) 2000-11-14
WO1999042427A1 (en) 1999-08-26
YU51000A (sh) 2002-11-15
GB9803521D0 (en) 1998-04-15
CA2321122A1 (en) 1999-08-26
DK1056701T3 (da) 2004-02-02
SK12052000A3 (sk) 2001-01-18
CZ20002927A3 (cs) 2000-12-13
JP2002503713A (ja) 2002-02-05
ID26857A (id) 2001-02-15
PL193315B1 (pl) 2007-01-31
EA002919B1 (ru) 2002-10-31
IL137214A0 (en) 2001-07-24
HUP0101354A2 (hu) 2002-03-28
BG104713A (en) 2001-03-30
ZA991232B (en) 1999-09-17
AR014961A1 (es) 2001-04-11
NO20003987L (no) 2000-08-07
EE200000473A (et) 2001-12-17
AU2524499A (en) 1999-09-06
EA200000851A1 (ru) 2001-02-26
UA57132C2 (uk) 2003-06-16
KR100755918B1 (ko) 2007-09-06
HUP0101354A3 (en) 2002-05-28
EP1056701A1 (en) 2000-12-06
CN1291178A (zh) 2001-04-11

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