HRP20000545A2 - E-2-/4-(4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy/ethanol and pharmaceutical compositions thereof - Google Patents

E-2-/4-(4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy/ethanol and pharmaceutical compositions thereof

Info

Publication number
HRP20000545A2
HRP20000545A2 HR20000545A HRP20000545A HRP20000545A2 HR P20000545 A2 HRP20000545 A2 HR P20000545A2 HR 20000545 A HR20000545 A HR 20000545A HR P20000545 A HRP20000545 A HR P20000545A HR P20000545 A2 HRP20000545 A2 HR P20000545A2
Authority
HR
Croatia
Prior art keywords
enyl
phenoxy
diphenyl
chloro
ethanol
Prior art date
Application number
HR20000545A
Other languages
English (en)
Inventor
Marja-Liisa Soedervall
Arja Kalapudas
Antti Viitanen
Eero Mantylae
Original Assignee
Orion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corp filed Critical Orion Corp
Publication of HRP20000545A2 publication Critical patent/HRP20000545A2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HR20000545A 1998-02-19 2000-08-18 E-2-/4-(4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy/ethanol and pharmaceutical compositions thereof HRP20000545A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9803521.5A GB9803521D0 (en) 1998-02-19 1998-02-19 New compounds and pharmaceutical compositions thereof
PCT/FI1999/000137 WO1999042427A1 (en) 1998-02-19 1999-02-19 E-2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]ethanol and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
HRP20000545A2 true HRP20000545A2 (en) 2001-02-28

Family

ID=10827263

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20000545A HRP20000545A2 (en) 1998-02-19 2000-08-18 E-2-/4-(4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy/ethanol and pharmaceutical compositions thereof

Country Status (33)

Country Link
US (1) US6395785B1 (tr)
EP (1) EP1056701B1 (tr)
JP (1) JP2002503713A (tr)
KR (1) KR100755918B1 (tr)
CN (1) CN1161314C (tr)
AR (1) AR014961A1 (tr)
AT (1) ATE252531T1 (tr)
AU (1) AU755798B2 (tr)
BG (1) BG64471B1 (tr)
BR (1) BR9907688A (tr)
CA (1) CA2321122C (tr)
CZ (1) CZ294315B6 (tr)
DE (1) DE69912247T2 (tr)
DK (1) DK1056701T3 (tr)
EA (1) EA002919B1 (tr)
EE (1) EE04233B1 (tr)
ES (1) ES2211038T3 (tr)
GB (1) GB9803521D0 (tr)
GE (1) GEP20022794B (tr)
HR (1) HRP20000545A2 (tr)
HU (1) HUP0101354A3 (tr)
ID (1) ID26857A (tr)
IL (1) IL137214A (tr)
NO (1) NO325595B1 (tr)
NZ (1) NZ505637A (tr)
PL (1) PL193315B1 (tr)
PT (1) PT1056701E (tr)
RS (1) RS49660B (tr)
SK (1) SK285940B6 (tr)
TR (1) TR200002037T2 (tr)
UA (1) UA57132C2 (tr)
WO (1) WO1999042427A1 (tr)
ZA (1) ZA991232B (tr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW593256B (en) * 1999-11-16 2004-06-21 Hormos Medical Oy Ltd Triphenylalkene derivatives and their use as selective estrogen receptor modulators
EP1705169A3 (en) * 1999-11-16 2006-11-15 Hormos Medical Ltd. Triphenylalkene derivatives and their use as selective estrogen receptor modulators
US20040248989A1 (en) 2003-06-05 2004-12-09 Risto Santti Method for the treatment or prevention of lower urinary tract symptoms
RU2480207C2 (ru) 2006-05-22 2013-04-27 Хормос Медикал Лтд. Способ лечения хронического абактериального простатита селективными модуляторами рецепторов эстрогена или ингибиторами ароматазы
US7504530B2 (en) 2007-02-14 2009-03-17 Hormos Medical Ltd. Methods for the preparation of fispemifene from ospemifene
JP5363344B2 (ja) 2007-02-14 2013-12-11 ホルモス メディカル リミテッド 治療に有用なトリフェニルブテン誘導体の調製方法
RS53353B (en) 2010-01-19 2014-10-31 Cambrex Karlskoga Ab NEW PROCEDURES FOR THE PRODUCTION OF BENZOPHENONE DERIVATIVES
WO2014060639A1 (en) 2012-10-19 2014-04-24 Fermion Oy A process for the preparation of ospemifene
EP2909163A1 (en) * 2012-10-19 2015-08-26 Fermion Oy A process for the preparation of ospemifene
CN104030896A (zh) * 2013-03-07 2014-09-10 天津药物研究院 一种简易去除欧司哌米芬特异杂质的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2126576B (en) 1982-06-25 1985-06-19 Farmos Group Limited Alkane and alkene derivatives
GB9418067D0 (en) 1994-09-07 1994-10-26 Orion Yhtymae Oy Triphenylethylenes for the prevention and treatment of osteoporosis
GB9604577D0 (en) * 1996-03-04 1996-05-01 Orion Yhtymae Oy Serum cholesterol lowering agent

Also Published As

Publication number Publication date
BG104713A (en) 2001-03-30
ZA991232B (en) 1999-09-17
HUP0101354A3 (en) 2002-05-28
AU2524499A (en) 1999-09-06
YU51000A (sh) 2002-11-15
EA200000851A1 (ru) 2001-02-26
RS49660B (sr) 2007-09-21
CZ294315B6 (cs) 2004-11-10
GEP20022794B (en) 2002-09-25
NO325595B1 (no) 2008-06-23
TR200002037T2 (tr) 2001-02-21
PT1056701E (pt) 2004-03-31
EP1056701A1 (en) 2000-12-06
WO1999042427A1 (en) 1999-08-26
BG64471B1 (bg) 2005-04-30
JP2002503713A (ja) 2002-02-05
IL137214A0 (en) 2001-07-24
KR20010040985A (ko) 2001-05-15
UA57132C2 (uk) 2003-06-16
BR9907688A (pt) 2000-11-14
NO20003987D0 (no) 2000-08-07
PL342445A1 (en) 2001-06-04
ID26857A (id) 2001-02-15
AR014961A1 (es) 2001-04-11
CN1161314C (zh) 2004-08-11
NZ505637A (en) 2002-10-25
DE69912247T2 (de) 2004-07-29
DE69912247D1 (de) 2003-11-27
EE200000473A (et) 2001-12-17
AU755798B2 (en) 2002-12-19
PL193315B1 (pl) 2007-01-31
KR100755918B1 (ko) 2007-09-06
US6395785B1 (en) 2002-05-28
GB9803521D0 (en) 1998-04-15
NO20003987L (no) 2000-08-07
HUP0101354A2 (hu) 2002-03-28
ATE252531T1 (de) 2003-11-15
EP1056701B1 (en) 2003-10-22
ES2211038T3 (es) 2004-07-01
CN1291178A (zh) 2001-04-11
DK1056701T3 (da) 2004-02-02
SK285940B6 (sk) 2007-11-02
CZ20002927A3 (cs) 2000-12-13
IL137214A (en) 2005-05-17
SK12052000A3 (sk) 2001-01-18
EE04233B1 (et) 2004-02-16
CA2321122A1 (en) 1999-08-26
CA2321122C (en) 2008-02-12
EA002919B1 (ru) 2002-10-31

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
ODBC Application rejected