AR014961A1 - Compuesto de fenoxietanol y su uso para preparar un medicamento - Google Patents
Compuesto de fenoxietanol y su uso para preparar un medicamentoInfo
- Publication number
- AR014961A1 AR014961A1 ARP990100642A ARP990100642A AR014961A1 AR 014961 A1 AR014961 A1 AR 014961A1 AR P990100642 A ARP990100642 A AR P990100642A AR P990100642 A ARP990100642 A AR P990100642A AR 014961 A1 AR014961 A1 AR 014961A1
- Authority
- AR
- Argentina
- Prior art keywords
- compound
- phenoxyethanol
- prepare
- medicinal product
- serum cholesterol
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 229960005323 phenoxyethanol Drugs 0.000 title 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- LUMKNAVTFCDUIE-WCWDXBQESA-N 2-[4-[(e)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]ethanol Chemical compound C1=CC(OCCO)=CC=C1C(\C=1C=CC=CC=1)=C(/CCCl)C1=CC=CC=C1 LUMKNAVTFCDUIE-WCWDXBQESA-N 0.000 abstract 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Se describe un compuesto, el E-2-[4-(4-cloro-1,2-difenil-but-1-enil)fenoxi] etanol (I), util en la reduccion de colesterol sérico y a composicionesfarmacéuticas del mismo. También se propone un método para reducir el colesterol sérico y unmétodo para la prevencion o tratamiento deateroesclerosis.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9803521.5A GB9803521D0 (en) | 1998-02-19 | 1998-02-19 | New compounds and pharmaceutical compositions thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
AR014961A1 true AR014961A1 (es) | 2001-04-11 |
Family
ID=10827263
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990100642A AR014961A1 (es) | 1998-02-19 | 1999-02-16 | Compuesto de fenoxietanol y su uso para preparar un medicamento |
Country Status (33)
Country | Link |
---|---|
US (1) | US6395785B1 (es) |
EP (1) | EP1056701B1 (es) |
JP (1) | JP2002503713A (es) |
KR (1) | KR100755918B1 (es) |
CN (1) | CN1161314C (es) |
AR (1) | AR014961A1 (es) |
AT (1) | ATE252531T1 (es) |
AU (1) | AU755798B2 (es) |
BG (1) | BG64471B1 (es) |
BR (1) | BR9907688A (es) |
CA (1) | CA2321122C (es) |
CZ (1) | CZ294315B6 (es) |
DE (1) | DE69912247T2 (es) |
DK (1) | DK1056701T3 (es) |
EA (1) | EA002919B1 (es) |
EE (1) | EE04233B1 (es) |
ES (1) | ES2211038T3 (es) |
GB (1) | GB9803521D0 (es) |
GE (1) | GEP20022794B (es) |
HR (1) | HRP20000545A2 (es) |
HU (1) | HUP0101354A3 (es) |
ID (1) | ID26857A (es) |
IL (1) | IL137214A (es) |
NO (1) | NO325595B1 (es) |
NZ (1) | NZ505637A (es) |
PL (1) | PL193315B1 (es) |
PT (1) | PT1056701E (es) |
RS (1) | RS49660B (es) |
SK (1) | SK285940B6 (es) |
TR (1) | TR200002037T2 (es) |
UA (1) | UA57132C2 (es) |
WO (1) | WO1999042427A1 (es) |
ZA (1) | ZA991232B (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1705169A3 (en) * | 1999-11-16 | 2006-11-15 | Hormos Medical Ltd. | Triphenylalkene derivatives and their use as selective estrogen receptor modulators |
TW593256B (en) * | 1999-11-16 | 2004-06-21 | Hormos Medical Oy Ltd | Triphenylalkene derivatives and their use as selective estrogen receptor modulators |
US20040248989A1 (en) | 2003-06-05 | 2004-12-09 | Risto Santti | Method for the treatment or prevention of lower urinary tract symptoms |
KR101505884B1 (ko) | 2006-05-22 | 2015-03-25 | 호르모스 메디칼 리미티드 | 만성 비세균성 전립선염 치료용 선택적 에스트로겐 수용체 조절제 또는 아로마타아제 저해제 |
CN101636372B (zh) | 2007-02-14 | 2013-03-27 | 霍尔莫斯医疗有限公司 | 有治疗价值的三苯基丁烯衍生物的制备方法 |
WO2008099060A2 (en) | 2007-02-14 | 2008-08-21 | Hormos Medical Ltd | Methods for the preparation of fispemifene from ospemifene |
DK2526080T3 (da) | 2010-01-19 | 2014-04-28 | Cambrex Karlskoga Ab | Nye fremgangsmåder til fremstilling af benzophenonderivater |
US20150321983A1 (en) * | 2012-10-19 | 2015-11-12 | Fermion Oy | A process for the preparation of ospemifene |
WO2014060639A1 (en) | 2012-10-19 | 2014-04-24 | Fermion Oy | A process for the preparation of ospemifene |
CN104030896A (zh) * | 2013-03-07 | 2014-09-10 | 天津药物研究院 | 一种简易去除欧司哌米芬特异杂质的方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2126576B (en) | 1982-06-25 | 1985-06-19 | Farmos Group Limited | Alkane and alkene derivatives |
GB9418067D0 (en) | 1994-09-07 | 1994-10-26 | Orion Yhtymae Oy | Triphenylethylenes for the prevention and treatment of osteoporosis |
GB9604577D0 (en) * | 1996-03-04 | 1996-05-01 | Orion Yhtymae Oy | Serum cholesterol lowering agent |
-
1998
- 1998-02-19 GB GBGB9803521.5A patent/GB9803521D0/en not_active Ceased
-
1999
- 1999-02-16 AR ARP990100642A patent/AR014961A1/es active IP Right Grant
- 1999-02-16 ZA ZA9901232A patent/ZA991232B/xx unknown
- 1999-02-19 CA CA002321122A patent/CA2321122C/en not_active Expired - Fee Related
- 1999-02-19 RS YUP-510/00A patent/RS49660B/sr unknown
- 1999-02-19 WO PCT/FI1999/000137 patent/WO1999042427A1/en active IP Right Grant
- 1999-02-19 EP EP99904899A patent/EP1056701B1/en not_active Expired - Lifetime
- 1999-02-19 NZ NZ505637A patent/NZ505637A/xx unknown
- 1999-02-19 UA UA2000095331A patent/UA57132C2/uk unknown
- 1999-02-19 BR BR9907688-8A patent/BR9907688A/pt not_active Application Discontinuation
- 1999-02-19 GE GEAP19995553A patent/GEP20022794B/en unknown
- 1999-02-19 KR KR1020007008982A patent/KR100755918B1/ko not_active IP Right Cessation
- 1999-02-19 DK DK99904899T patent/DK1056701T3/da active
- 1999-02-19 CZ CZ20002927A patent/CZ294315B6/cs not_active IP Right Cessation
- 1999-02-19 AU AU25244/99A patent/AU755798B2/en not_active Ceased
- 1999-02-19 EA EA200000851A patent/EA002919B1/ru not_active IP Right Cessation
- 1999-02-19 ID IDW20001841A patent/ID26857A/id unknown
- 1999-02-19 JP JP2000532381A patent/JP2002503713A/ja active Pending
- 1999-02-19 PL PL342445A patent/PL193315B1/pl unknown
- 1999-02-19 ES ES99904899T patent/ES2211038T3/es not_active Expired - Lifetime
- 1999-02-19 DE DE69912247T patent/DE69912247T2/de not_active Expired - Fee Related
- 1999-02-19 CN CNB998030139A patent/CN1161314C/zh not_active Expired - Fee Related
- 1999-02-19 US US09/601,612 patent/US6395785B1/en not_active Expired - Fee Related
- 1999-02-19 TR TR2000/02037T patent/TR200002037T2/xx unknown
- 1999-02-19 AT AT99904899T patent/ATE252531T1/de not_active IP Right Cessation
- 1999-02-19 IL IL13721499A patent/IL137214A/xx unknown
- 1999-02-19 EE EEP200000473A patent/EE04233B1/xx not_active IP Right Cessation
- 1999-02-19 PT PT99904899T patent/PT1056701E/pt unknown
- 1999-02-19 SK SK1205-2000A patent/SK285940B6/sk unknown
- 1999-02-19 HU HU0101354A patent/HUP0101354A3/hu unknown
-
2000
- 2000-08-07 NO NO20003987A patent/NO325595B1/no unknown
- 2000-08-18 HR HR20000545A patent/HRP20000545A2/xx not_active Application Discontinuation
- 2000-08-28 BG BG104713A patent/BG64471B1/bg unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU3274399A (en) | Activated vitamin D3 emulsion-type lotions | |
AR014961A1 (es) | Compuesto de fenoxietanol y su uso para preparar un medicamento | |
BR0114576A (pt) | Composto, composição farmacêutica, uso de um composto, método de tratar um estado doentio e processo para preparar um composto | |
ES2157307T3 (es) | Composicion topica que contiene un antagonista de sustancia p. | |
CA2248032A1 (en) | Serum cholesterol lowering agent | |
EE04356B1 (et) | aP2 inhibiitor kasutamiseks suhkurtõve ravis ja seda sisaldav ravimkoostis | |
GB2334446B (en) | Aqueous compositions compromising a lipid and a lanolin-derived surfactant,and their use | |
DE60017878D1 (de) | Kombinationspräparate zur behandlung von erkrankungen, die mit angiogenese verbunden sind | |
FR2811561B1 (fr) | Composition, notamment cosmetique, renfermant la dhea et/ou un precurseur ou derive chimique ou biologique de celle-ci, et un inhibiteur de metalloproteinase | |
BR0009421A (pt) | Inibidores de ligação lfa-1 aos icams e uso dos mesmos | |
AU6997200A (en) | No-liberating topically applicable composition as biological agent, production and utilization thereof as dermatological and/or cosmetic product | |
DK1185267T3 (da) | Dermale bedövelsesmidler | |
SE9801647D0 (sv) | Therapeutic composition | |
DE69923332D1 (de) | Rückfettende ester auf basis von capryl-alkohol und isostearinsäure | |
ATE284215T1 (de) | Transdermale systeme enthaltend zwei wirkstoffe in getrennten abteilungen, ihre herstellungsverfahren und verwendung als arzneimittel | |
AU5422899A (en) | Dry extract of henna, method for producing said extract and use of the same | |
NO992006D0 (no) | Nye cis-3,4-kromanderivater som kan anvendes ved forhindring eller behandling av °strogenrelaterte sykdommer eller syndromer | |
TR199901546A2 (xx) | Pirolidinil hidroksamik asid bile�imleri i�in y�ntem. | |
IL113074A (en) | Hypocholesterolemic antiatherosclerotic and hypotriglyceridemic pharmaceutical compositions comprising derivatives of mercaptoacetamido-oxopyrrolo (and pyrido) benzazepinecarboxylic acids | |
BR9902346A (pt) | Processo para preparação de derivados de ácido propiÈnico | |
ES2122184T3 (es) | Utilizacion de derivados de la benzomorfolina en composiciones cosmeticas o dermofarmaceuticas con accion despigmentante. | |
PT1165596E (pt) | Derivados de 14,15-alfa-metileno equilenina processos para producao dos mesmos e medicamentos que os contem | |
MX9704608A (es) | Acidos fluoroalquilglicosiduronicos y 6(3)-lactonas correspondientes, preparacion y usos. | |
MX9706435A (es) | Estabilizacion de un retinoide no estable en emulsiones de aceite en agua para composiciones para el cuidado de la piel. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration |