ES2157307T3 - Composicion topica que contiene un antagonista de sustancia p. - Google Patents
Composicion topica que contiene un antagonista de sustancia p.Info
- Publication number
- ES2157307T3 ES2157307T3 ES95402502T ES95402502T ES2157307T3 ES 2157307 T3 ES2157307 T3 ES 2157307T3 ES 95402502 T ES95402502 T ES 95402502T ES 95402502 T ES95402502 T ES 95402502T ES 2157307 T3 ES2157307 T3 ES 2157307T3
- Authority
- ES
- Spain
- Prior art keywords
- irritant
- product
- composition containing
- antagonist
- substance antagonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/046—Tachykinins, e.g. eledoisins, substance P; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
LA INVENCION SE REFIERE A UNA COMPOSICION TERAPEUTICA DE APLICACION TOPICA QUE CONTIENE AL MENOS UN PRODUCTO DE EFECTO SECUNDARIO IRRITANTE Y UN ANTAGONISTA DE SUSTANCIA P PARA REDUCIR INCLUSO ELIMINAR EL EFECTO IRRITANTE DE ESTE PRODUCTO. SE REFIERE TAMBIEN A LA UTILIZACION DE UN ANTAGONISTA DE SUSTANCIA P PARA LA PREPARACION DE UNA COMPOSICION FARMACEUTICA EN LA APLICACION TOPICA QUE CONTIENE AL MENOS UN PRODUCTO DE EFECTO SECUNDARIO IRRITANTE PARA REDUCIR INCLUSO ELIMINAR EL EFECTO IRRITANTE DE ESTE PRODUCTO. EL ANTAGONISTA DE SUSTANCIA P PUEDE SER UN COMPUESTO PEPTIDICO O UN COMPUESTO NITROGENADO O UN COMPUESTO HETEROCICLICO NITROGENADO, AZUFRADO U OXIGENADO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9415253A FR2728166A1 (fr) | 1994-12-19 | 1994-12-19 | Composition topique contenant un antagoniste de substance p |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2157307T3 true ES2157307T3 (es) | 2001-08-16 |
Family
ID=9469931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95402502T Expired - Lifetime ES2157307T3 (es) | 1994-12-19 | 1995-11-09 | Composicion topica que contiene un antagonista de sustancia p. |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US5824650A (es) |
| EP (1) | EP0722736B1 (es) |
| JP (1) | JPH08208505A (es) |
| AR (1) | AR002007A1 (es) |
| AT (1) | ATE198986T1 (es) |
| BR (1) | BR9505408A (es) |
| CA (1) | CA2165521C (es) |
| DE (1) | DE69520032T2 (es) |
| DK (1) | DK0722736T3 (es) |
| ES (1) | ES2157307T3 (es) |
| FR (1) | FR2728166A1 (es) |
| GR (1) | GR3035652T3 (es) |
| HU (1) | HU218936B (es) |
| MX (1) | MX9505182A (es) |
| PL (1) | PL311918A1 (es) |
| PT (1) | PT722736E (es) |
| RU (1) | RU2124353C1 (es) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6203803B1 (en) | 1994-12-14 | 2001-03-20 | Societe L'oreal S.A. | Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained |
| US6139850A (en) * | 1994-12-21 | 2000-10-31 | Cosmederm Technologies | Formulations and methods for reducing skin irritation |
| US7404967B2 (en) * | 1994-12-21 | 2008-07-29 | Cosmederm, Inc. | Topical product formulations containing strontium for reducing skin irritation |
| FR2732221B1 (fr) * | 1995-03-28 | 1997-04-25 | Oreal | Utilisation d'un antagoniste de cgrp pour traiter les rougeurs cutanees d'origine neurogene et composition obtenue |
| US20040071762A1 (en) * | 1996-05-29 | 2004-04-15 | Scotia Holdings Plc | Diagnostic test for schizophrenia, using niacin |
| US7217714B1 (en) | 1998-12-23 | 2007-05-15 | Agouron Pharmaceuticals, Inc. | CCR5 modulators |
| PE20001420A1 (es) | 1998-12-23 | 2000-12-18 | Pfizer | Moduladores de ccr5 |
| DE19924277A1 (de) * | 1999-05-27 | 2000-11-30 | Beiersdorf Ag | Zubereitungen von Emulsionstyp W/O mit erhöhtem Wassergehalt mit einem Gehalt an mittelpolaren Lipiden und Siliconemulgatoren und gegebenenfalls kationischen Polymeren |
| US6861397B2 (en) * | 1999-06-23 | 2005-03-01 | The Dial Corporation | Compositions having enhanced deposition of a topically active compound on a surface |
| US6107261A (en) | 1999-06-23 | 2000-08-22 | The Dial Corporation | Compositions containing a high percent saturation concentration of antibacterial agent |
| RU2161974C1 (ru) * | 2000-01-20 | 2001-01-20 | Общество с ограниченной ответственностью "Клиника Института биорегуляции и геронтологии" | Лечебно-профилактическое средство для ухода за кожей (варианты) |
| KR100366439B1 (ko) * | 2000-02-21 | 2003-01-09 | 주식회사 대웅 | 상피세포 성장인자를 유효성분으로 하는 안정한 약제학적조성물 |
| US6689399B1 (en) | 2000-03-16 | 2004-02-10 | James R. Dickson | Transdermal delivery of an anti-inflammatory composition |
| US8512718B2 (en) | 2000-07-03 | 2013-08-20 | Foamix Ltd. | Pharmaceutical composition for topical application |
| GB0029018D0 (en) * | 2000-11-28 | 2001-01-10 | Strakan Group Plc | Dermatological formulations |
| ITPD20010187A1 (it) * | 2001-07-23 | 2003-01-23 | Cutech Srl | Trattamento del follicolo polifero, in particolare contro la caduta dei capelli |
| RU2190394C1 (ru) * | 2001-11-08 | 2002-10-10 | ОАО Нижегородский химико-фармацевтический завод | Фармацевтический состав, обладающий противогрибковой активностью, и способ его получения |
| US7820186B2 (en) | 2001-12-21 | 2010-10-26 | Galderma Research & Development | Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt |
| EP1380639B1 (en) * | 2002-01-15 | 2009-09-09 | OOO "Nauchno-Proizvodstvennoe Obiedinenie "Opytnaya Vodno-Analiticheskaya Laboratoria" | Method for producing a water-alcohol solution |
| RU2216582C2 (ru) * | 2002-01-15 | 2003-11-20 | Сорокин Валерий Николаевич | Способ получения водно-спиртового раствора и алкогольный, фармацевтический и косметический продукты, изготовленные с его использованием |
| RU2243992C2 (ru) * | 2002-03-28 | 2005-01-10 | Сорокин Валерий Николаевич | Способ получения водно-спиртового раствора и алкогольный, фармацевтический и косметический продукты, изготовленные с его использованием |
| JP4473491B2 (ja) * | 2002-05-28 | 2010-06-02 | 株式会社資生堂 | 毛穴縮小剤 |
| US6723755B2 (en) | 2002-06-12 | 2004-04-20 | Piotr Chomczynski | Method of treating rosacea |
| IL152486A0 (en) | 2002-10-25 | 2003-05-29 | Meir Eini | Alcohol-free cosmetic and pharmaceutical foam carrier |
| US8486376B2 (en) | 2002-10-25 | 2013-07-16 | Foamix Ltd. | Moisturizing foam containing lanolin |
| US8900554B2 (en) | 2002-10-25 | 2014-12-02 | Foamix Pharmaceuticals Ltd. | Foamable composition and uses thereof |
| US20080138296A1 (en) | 2002-10-25 | 2008-06-12 | Foamix Ltd. | Foam prepared from nanoemulsions and uses |
| US10117812B2 (en) | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
| US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
| US7700076B2 (en) | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
| AU2003279493B2 (en) | 2002-10-25 | 2009-08-20 | Foamix Pharmaceuticals Ltd. | Cosmetic and pharmaceutical foam |
| US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| US8119109B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Foamable compositions, kits and methods for hyperhidrosis |
| US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
| US8119150B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Non-flammable insecticide composition and uses thereof |
| US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
| US7704518B2 (en) | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
| US7575739B2 (en) | 2003-04-28 | 2009-08-18 | Foamix Ltd. | Foamable iodine composition |
| US8795693B2 (en) | 2003-08-04 | 2014-08-05 | Foamix Ltd. | Compositions with modulating agents |
| US8486374B2 (en) | 2003-08-04 | 2013-07-16 | Foamix Ltd. | Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses |
| RU2257204C2 (ru) * | 2003-08-12 | 2005-07-27 | Открытое Акционерное Общество "Фармакон" (ОАО "Фармакон") | Противогрибковая гелевая фармацевтическая композиция и способ ее получения |
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| US7872050B2 (en) * | 2005-03-14 | 2011-01-18 | Yaupon Therapeutics Inc. | Stabilized compositions of volatile alkylating agents and methods of using thereof |
| US8501818B2 (en) * | 2005-03-14 | 2013-08-06 | Ceptaris Therapeutics, Inc. | Stabilized compositions of alkylating agents and methods of using same |
| US20110039943A1 (en) * | 2005-03-14 | 2011-02-17 | Robert Alonso | Methods for treating skin disorders with topical nitrogen mustard compositions |
| MX2007014101A (es) | 2005-05-09 | 2009-02-13 | Foamix Ltd | Vehiculo espumable y composiciones farmaceuticas del mismo. |
| EP1888033B1 (en) * | 2005-06-09 | 2014-02-19 | Meda AB | Method and composition for treating inflammatory disorders |
| US20070154448A1 (en) * | 2005-11-22 | 2007-07-05 | Ted Reid | Methods and compositions using Substance P to promote wound healing |
| MY177591A (en) | 2006-10-16 | 2020-09-22 | Lion Corp | Nk1 receptor antagonist composition |
| US20080260655A1 (en) | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
| FR2910321B1 (fr) | 2006-12-21 | 2009-07-10 | Galderma Res & Dev S N C Snc | Gel creme comprenant au moins un retinoide et du peroxyde de benzole |
| CN101720226B (zh) * | 2007-05-11 | 2013-01-30 | 芦荟研究实验室公司 | 用于皮肤增强的芦荟制剂 |
| US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
| US9439857B2 (en) | 2007-11-30 | 2016-09-13 | Foamix Pharmaceuticals Ltd. | Foam containing benzoyl peroxide |
| US8518376B2 (en) | 2007-12-07 | 2013-08-27 | Foamix Ltd. | Oil-based foamable carriers and formulations |
| WO2009090495A2 (en) | 2007-12-07 | 2009-07-23 | Foamix Ltd. | Oil and liquid silicone foamable carriers and formulations |
| EP2242476A2 (en) | 2008-01-14 | 2010-10-27 | Foamix Ltd. | Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses |
| SI2273876T1 (sl) * | 2008-03-27 | 2019-09-30 | Helsinn Healthcare Sa | Stabilizirani sestavki alkilirajočih sredstev in metod za uporabo le-teh |
| EP2177208A1 (en) * | 2008-10-17 | 2010-04-21 | Ferrer Internacional, S.A. | Pharmaceutical topical compositions |
| US7833829B2 (en) * | 2008-10-28 | 2010-11-16 | Honeywell International Inc. | MEMS devices and methods of assembling micro electromechanical systems (MEMS) |
| JP5425229B2 (ja) * | 2009-02-24 | 2014-02-26 | ノバルティス アーゲー | Nk受容体アンタゴニストの使用 |
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| WO2011013009A2 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
| CA2769677A1 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
| US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
| MX359879B (es) | 2009-10-02 | 2018-10-12 | Foamix Pharmaceuticals Ltd | Composiciones tópicas de tetraciclina. |
| RU2485955C2 (ru) * | 2010-11-17 | 2013-06-27 | Леонид Леонидович Клопотенко | Фармацевтическая композиция, содержащая флуконазол, и/или кетоконазол, и/или тербинафин и липосомы для местного применения |
| KR101729096B1 (ko) | 2012-03-21 | 2017-04-21 | 코스메덤 바이오사이언스, 인코퍼레이티드 | 통증, 가려움증 및 염증을 치료하기 위한 국소 투여된 스트론튬-함유 복합체 |
| US11235002B2 (en) | 2015-08-21 | 2022-02-01 | Galleon Labs Llc | Strontium based compositions and formulations for pain, pruritus, and inflammation |
| CA2978573A1 (en) | 2016-09-08 | 2018-03-08 | Foamix Pharmaceuticals Ltd. | Compositions and methods for treating rosacea and acne |
| US11708135B2 (en) | 2018-05-30 | 2023-07-25 | Philip John Milanovich | Waste management system |
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| US5232929A (en) | 1990-11-28 | 1993-08-03 | Pfizer Inc. | 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use |
| ATE94399T1 (de) * | 1990-01-29 | 1993-10-15 | Wogepharm Gmbh | Verfahren zur herstellung von mitteln zur therapie von hauterkrankungen. |
| WO1991012266A1 (fr) | 1990-02-15 | 1991-08-22 | Fujisawa Pharmaceutical Co., Ltd. | Compose peptidique |
| US5344532A (en) | 1990-03-09 | 1994-09-06 | Joseph Adrian A | Ultrasonic energy producing device |
| FR2662607B1 (fr) * | 1990-05-30 | 1992-08-28 | Oreal | Composition destinee a etre utilisee pour freiner la chute des cheveux et pour induire et stimuler leur croissance, contenant des derives d'alkyl-2 amino-4 (ou dialkyl-2-4) pyrimidine oxyde-3 . |
| PL169187B1 (pl) | 1990-05-31 | 1996-06-28 | Pfizer | Sposób wytwarzania podstawionych piperydyn PL PL PL |
| EP0532527B1 (en) | 1990-06-01 | 1994-11-09 | Pfizer Inc. | 3-amino-2-aryl quinuclidines, process for their preparation and pharmaceutical compositions containing them |
| DE69114117T2 (de) | 1990-12-21 | 1996-03-21 | Fujisawa Pharmaceutical Co | Neue Verwendung von Peptidderivat. |
| WO1992012151A1 (en) | 1991-01-10 | 1992-07-23 | Pfizer Inc. | N-alkyl quinuclidinium salts as substance p antagonists |
| EP0499313B1 (en) | 1991-02-11 | 1997-06-11 | MERCK SHARP & DOHME LTD. | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy |
| EP0573522B1 (en) | 1991-03-01 | 1994-12-14 | Pfizer Inc. | 1-azabicyclo[3.2.2]nonan-3-amine derivatives |
| BR9205807A (pt) | 1991-03-26 | 1994-06-28 | Pfizer | Preparação estéreo-seletiva de piperidinas substituidas |
| FR2677361A1 (fr) | 1991-06-04 | 1992-12-11 | Adir | Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2676446B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2676447B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveaux derives du thiopyranopyrrole et leur preparation. |
| FR2676442B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2676443B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveaux derives de perhydroisoindole et leur preparation. |
| FI935134A7 (fi) | 1991-05-22 | 1993-11-19 | Pfizer | Substituoidut 3-aminokinuklidiinit |
| GB9113219D0 (en) | 1991-06-19 | 1991-08-07 | Fujisawa Pharmaceutical Co | Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same |
| BR9206161A (pt) | 1991-06-20 | 1995-10-31 | Pfizer | Derivados fluoroalcoxibenzilamino de heterociclos contendo nitrogénio |
| TW202432B (es) | 1991-06-21 | 1993-03-21 | Pfizer | |
| US5288730A (en) | 1991-06-24 | 1994-02-22 | Merck Sharp & Dohme Limited | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy |
| WO1993001169A2 (en) | 1991-07-05 | 1993-01-21 | Merck Sharp & Dohme Limited | Aromatic compounds, pharmaceutical compositions containing them and their use in therapy |
| ATE133657T1 (de) | 1991-07-05 | 1996-02-15 | Merck Sharp & Dohme | Aromatische verbindungen, diese enthaltende pharmazeutische zusammensetzungen und ihre therapeutische anwendung |
| WO1993001159A1 (en) | 1991-07-10 | 1993-01-21 | Merck Sharp & Dohme Limited | Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy |
| DE69208089T2 (de) | 1991-07-10 | 1996-08-22 | Merck Sharp & Dohme | Aromatische verbindungen diese enthaltende pharmazeutische zusammensetzungen und ihre therapeutische verwendung |
| MY110227A (en) | 1991-08-12 | 1998-03-31 | Ciba Geigy Ag | 1-acylpiperindine compounds. |
| CA2112397A1 (en) | 1991-08-20 | 1993-03-04 | Raymond Baker | Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them |
| FI941212L (fi) | 1991-09-26 | 1994-03-15 | Pfizer | Fuusioituneet trisykliset, typpeä sisältävät heterosykliset yhdisteet |
| JP2553020B2 (ja) | 1991-11-07 | 1996-11-13 | 吉富製薬株式会社 | キヌクリジン化合物およびその医薬用途 |
| FI942187L (fi) | 1991-11-12 | 1994-05-11 | Pfizer | Asyklisiä etyleenidiamiinijohdannaisia aine P-reseptoriantagonisteina |
| CA2083891A1 (en) | 1991-12-03 | 1993-06-04 | Angus Murray Macleod | Heterocyclic compounds, compositions containing them and their use in therapy |
| US5569662A (en) * | 1992-03-23 | 1996-10-29 | Pfizer Inc. | Quinuclidine derivatives as substance P antagonists |
| DE4227203C2 (de) * | 1992-08-17 | 1994-03-24 | Kao Corp Gmbh | Mittel und Verfahren zur Haarbehandlung |
| JP2656699B2 (ja) | 1992-10-21 | 1997-09-24 | ファイザー製薬株式会社 | 置換ベンジルアミノキヌクリジン |
| US5716625A (en) * | 1994-12-21 | 1998-02-10 | Cosmederm Technologies | Formulations and methods for reducing skin irritation |
-
1994
- 1994-12-19 FR FR9415253A patent/FR2728166A1/fr active Granted
-
1995
- 1995-11-09 AT AT95402502T patent/ATE198986T1/de not_active IP Right Cessation
- 1995-11-09 DE DE69520032T patent/DE69520032T2/de not_active Revoked
- 1995-11-09 PT PT95402502T patent/PT722736E/pt unknown
- 1995-11-09 DK DK95402502T patent/DK0722736T3/da active
- 1995-11-09 EP EP95402502A patent/EP0722736B1/fr not_active Revoked
- 1995-11-09 ES ES95402502T patent/ES2157307T3/es not_active Expired - Lifetime
- 1995-12-11 MX MX9505182A patent/MX9505182A/es unknown
- 1995-12-13 BR BR9505408A patent/BR9505408A/pt active Search and Examination
- 1995-12-15 AR ARP950100577A patent/AR002007A1/es unknown
- 1995-12-18 CA CA002165521A patent/CA2165521C/fr not_active Expired - Fee Related
- 1995-12-18 JP JP7329297A patent/JPH08208505A/ja active Pending
- 1995-12-18 HU HU9503623A patent/HU218936B/hu not_active IP Right Cessation
- 1995-12-18 PL PL95311918A patent/PL311918A1/xx unknown
- 1995-12-18 RU RU95121151A patent/RU2124353C1/ru active
- 1995-12-19 US US08/575,682 patent/US5824650A/en not_active Expired - Lifetime
-
1998
- 1998-06-15 US US09/094,558 patent/US5972892A/en not_active Expired - Lifetime
-
2001
- 2001-03-29 GR GR20010400502T patent/GR3035652T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2124353C1 (ru) | 1999-01-10 |
| HU9503623D0 (en) | 1996-02-28 |
| PT722736E (pt) | 2001-05-31 |
| DE69520032T2 (de) | 2001-05-23 |
| JPH08208505A (ja) | 1996-08-13 |
| CA2165521A1 (fr) | 1996-06-20 |
| AR002007A1 (es) | 1998-01-07 |
| US5972892A (en) | 1999-10-26 |
| HU218936B (hu) | 2001-01-29 |
| FR2728166A1 (fr) | 1996-06-21 |
| ATE198986T1 (de) | 2001-02-15 |
| HUT74830A (en) | 1997-02-28 |
| PL311918A1 (en) | 1996-06-24 |
| GR3035652T3 (en) | 2001-06-29 |
| FR2728166B1 (es) | 1997-02-07 |
| CA2165521C (fr) | 2002-07-16 |
| BR9505408A (pt) | 1997-10-28 |
| EP0722736A1 (fr) | 1996-07-24 |
| US5824650A (en) | 1998-10-20 |
| DK0722736T3 (da) | 2001-04-02 |
| EP0722736B1 (fr) | 2001-01-31 |
| MX9505182A (es) | 1997-02-28 |
| DE69520032D1 (de) | 2001-03-08 |
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