TR199801915T2 - Benzotiofenler, bunlari ihtiva eden formülasyonlar ve yöntemler. - Google Patents
Benzotiofenler, bunlari ihtiva eden formülasyonlar ve yöntemler.Info
- Publication number
- TR199801915T2 TR199801915T2 TR1998/01915T TR9801915T TR199801915T2 TR 199801915 T2 TR199801915 T2 TR 199801915T2 TR 1998/01915 T TR1998/01915 T TR 1998/01915T TR 9801915 T TR9801915 T TR 9801915T TR 199801915 T2 TR199801915 T2 TR 199801915T2
- Authority
- TR
- Turkey
- Prior art keywords
- benzothiophenes
- methods
- formulations containing
- formula
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Thin Film Transistor (AREA)
Abstract
Bu bulus formül (I)e sahip bilesikler ve bunlarn farmasötik açidan kabuledilebilir tuzlarini ve solvatlarini saglar; bu bilesik tanecikli bir yapida olmasi ve spesifik bir boy araligina sahip olmasi ile karakterize edilir. Bu bulus ayrica formül (I)e sahip bilesikler ihtiva eden veya bunlar kullanilarak formüle edilmis farmasötik terkipler ve bu gibi bilesiklerin, osteoporoz, serum lipidi düsürülmesi ve meme kanseri dahil insan hastaliklarini hafifletmek için kullanimini saglar.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1416796P | 1996-03-26 | 1996-03-26 | |
GBGB9607110.5A GB9607110D0 (en) | 1996-04-04 | 1996-04-04 | Benzothiopenes formulations containing same and methods |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199801915T2 true TR199801915T2 (tr) | 1998-12-21 |
Family
ID=26309061
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR1998/01915T TR199801915T2 (tr) | 1996-03-26 | 1997-03-20 | Benzotiofenler, bunlari ihtiva eden formülasyonlar ve yöntemler. |
Country Status (30)
Country | Link |
---|---|
EP (2) | EP0910369B1 (tr) |
JP (5) | JP2000507268A (tr) |
CN (1) | CN1162153C (tr) |
AR (1) | AR006387A1 (tr) |
AT (1) | ATE464897T1 (tr) |
AU (1) | AU723797B2 (tr) |
BR (1) | BR9708248A (tr) |
CA (1) | CA2250191C (tr) |
CO (1) | CO4780022A1 (tr) |
CZ (1) | CZ300341B6 (tr) |
DE (1) | DE69739855D1 (tr) |
DK (1) | DK0910369T3 (tr) |
EA (1) | EA001257B1 (tr) |
ES (1) | ES2341399T3 (tr) |
HK (1) | HK1020671A1 (tr) |
ID (1) | ID19813A (tr) |
IL (2) | IL126320A (tr) |
ME (2) | ME00074B (tr) |
MY (1) | MY115533A (tr) |
NO (1) | NO320894B1 (tr) |
NZ (1) | NZ332036A (tr) |
PL (1) | PL191148B1 (tr) |
PT (1) | PT910369E (tr) |
RO (1) | RO121117B1 (tr) |
SI (1) | SI0910369T1 (tr) |
TR (1) | TR199801915T2 (tr) |
TW (1) | TW513421B (tr) |
UA (1) | UA57596C2 (tr) |
WO (1) | WO1997035571A1 (tr) |
YU (1) | YU41898A (tr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ300341B6 (cs) * | 1996-03-26 | 2009-04-22 | Eli Lilly And Company | Farmaceutická kompozice obsahující raloxifen |
ZA992858B (en) | 1996-10-30 | 1999-07-29 | Lilly Co Eli | Methods of preventing breast cancer. |
IL122026A0 (en) * | 1996-10-30 | 1998-03-10 | Lilly Co Eli | Improvements in or relating to the prophylaxis of breast cancer |
AU2003266940B2 (en) | 2002-09-30 | 2007-02-08 | A/S Gea Farmaceutisk Fabrik | Novel raloxifene acid addition salts and/or solvates thereof, improved method for purification of said raloxifene acid addition salts and/or solvates thereof and pharmaceutical compositions comprising these |
KR20090082399A (ko) | 2006-10-17 | 2009-07-30 | 씨아이피엘에이 엘티디. | 벤조티오펜 화합물의 결정형 및 그의 제조방법 |
WO2009080364A1 (en) * | 2007-12-21 | 2009-07-02 | Synthon B.V. | Raloxifene composition |
SI2373305T1 (sl) * | 2008-12-11 | 2017-09-29 | Besins Healthcare Luxembourg Sarl | Transdermalni farmacevtski sestavki, ki obsegajo serm |
ES2437916T3 (es) | 2009-07-02 | 2014-01-15 | Synthon B.V. | Composición de raloxifeno |
WO2011099942A1 (en) | 2010-02-09 | 2011-08-18 | Silverstone Pharma | New addition salts of raloxifene, process for the preparation thereof and use thereof in therapy |
GB201515391D0 (en) * | 2015-08-28 | 2015-10-14 | Amazentis Sa | Compositions |
GB201515387D0 (en) * | 2015-08-28 | 2015-10-14 | Amazentis Sa | Compositions |
EP3251661B1 (en) * | 2016-05-30 | 2020-12-23 | Sun Pharmaceutical Industries Limited | Raloxifene sprinkle composition |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
US4380635A (en) | 1981-04-03 | 1983-04-19 | Eli Lilly And Company | Synthesis of acylated benzothiophenes |
US4418068A (en) * | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
JPS63112519A (ja) * | 1986-10-28 | 1988-05-17 | Shin Etsu Chem Co Ltd | ニフエジピン製剤の製造方法 |
NL9000634A (nl) * | 1990-03-20 | 1991-10-16 | Catharina Ziekenhuis Stichting | Suspensie-injectiepreparaat op waterbasis, werkwijze voor de bereiding daarvan en toepassing van dit preparaat voor pijnbestrijding. |
TW366342B (en) * | 1992-07-28 | 1999-08-11 | Lilly Co Eli | The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss |
JP3492688B2 (ja) * | 1992-10-09 | 2004-02-03 | 鐘淵化学工業株式会社 | 微細な造粒体の製造方法 |
US5482949A (en) * | 1993-03-19 | 1996-01-09 | Eli Lilly And Company | Sulfonate derivatives of 3-aroylbenzo[b]thiophenes |
US5482950A (en) * | 1993-10-15 | 1996-01-09 | Eli Lilly And Company | Methods for lowering serum cholesterol |
JPH09506898A (ja) * | 1993-12-21 | 1997-07-08 | イーライ・リリー・アンド・カンパニー | 非ペプチドタキキニン受容体アンタゴニスト |
US5478847A (en) * | 1994-03-02 | 1995-12-26 | Eli Lilly And Company | Methods of use for inhibiting bone loss and lowering serum cholesterol |
ZA951497B (en) * | 1994-03-02 | 1996-08-23 | Lilly Co Eli | Orally administerable pharmaceutical formulations |
US6723739B1 (en) * | 1994-05-20 | 2004-04-20 | Eli Lilly And Company | Glucopyranoside benzothiophenes |
US5494920A (en) * | 1994-08-22 | 1996-02-27 | Eli Lilly And Company | Methods of inhibiting viral replication |
CO4410190A1 (es) * | 1994-09-19 | 1997-01-09 | Lilly Co Eli | 3-[4-(2-AMINOETOXI)-BENZOIL]-2-ARIL-6-HIDROXIBENZO [b] TIOFENO CRISTALINO |
US5494929A (en) * | 1995-01-12 | 1996-02-27 | Eli Lilly And Company | Methods of inhibiting growth hormone effects |
US5532254A (en) | 1995-06-07 | 1996-07-02 | Eli Lilly And Company | Modulation of calcium channels using benzothiophenes |
CZ300341B6 (cs) * | 1996-03-26 | 2009-04-22 | Eli Lilly And Company | Farmaceutická kompozice obsahující raloxifen |
-
1997
- 1997-03-20 CZ CZ0305398A patent/CZ300341B6/cs not_active IP Right Cessation
- 1997-03-20 SI SI9730794T patent/SI0910369T1/sl unknown
- 1997-03-20 AT AT97915139T patent/ATE464897T1/de active
- 1997-03-20 IL IL12632097A patent/IL126320A/en not_active IP Right Cessation
- 1997-03-20 CA CA002250191A patent/CA2250191C/en not_active Expired - Fee Related
- 1997-03-20 IL IL140742A patent/IL140742A/en not_active IP Right Cessation
- 1997-03-20 EP EP97915139A patent/EP0910369B1/en not_active Revoked
- 1997-03-20 EA EA199800865A patent/EA001257B1/ru not_active IP Right Cessation
- 1997-03-20 AU AU22154/97A patent/AU723797B2/en not_active Expired
- 1997-03-20 WO PCT/US1997/004259 patent/WO1997035571A1/en not_active Application Discontinuation
- 1997-03-20 ME MEP-2008-183A patent/ME00074B/me unknown
- 1997-03-20 DK DK97915139.6T patent/DK0910369T3/da active
- 1997-03-20 TR TR1998/01915T patent/TR199801915T2/tr unknown
- 1997-03-20 CN CNB971932492A patent/CN1162153C/zh not_active Expired - Lifetime
- 1997-03-20 ME MEP-183/08A patent/MEP18308A/xx unknown
- 1997-03-20 PT PT97915139T patent/PT910369E/pt unknown
- 1997-03-20 PL PL329051A patent/PL191148B1/pl unknown
- 1997-03-20 BR BR9708248A patent/BR9708248A/pt active IP Right Grant
- 1997-03-20 ES ES97915139T patent/ES2341399T3/es not_active Expired - Lifetime
- 1997-03-20 DE DE69739855T patent/DE69739855D1/de not_active Expired - Lifetime
- 1997-03-20 NZ NZ332036A patent/NZ332036A/en not_active IP Right Cessation
- 1997-03-20 EP EP09165873A patent/EP2266560A1/en not_active Withdrawn
- 1997-03-20 RO RO98-01419A patent/RO121117B1/ro unknown
- 1997-03-20 UA UA98095028A patent/UA57596C2/uk unknown
- 1997-03-20 JP JP9534467A patent/JP2000507268A/ja not_active Withdrawn
- 1997-03-21 CO CO97015459A patent/CO4780022A1/es unknown
- 1997-03-24 MY MYPI97001237A patent/MY115533A/en unknown
- 1997-03-24 ID IDP970956A patent/ID19813A/id unknown
- 1997-03-25 AR ARP970101196A patent/AR006387A1/es not_active Application Discontinuation
- 1997-03-26 TW TW086103861A patent/TW513421B/zh not_active IP Right Cessation
-
1998
- 1998-09-24 NO NO19984444A patent/NO320894B1/no not_active IP Right Cessation
- 1998-09-25 YU YU41898A patent/YU41898A/sh unknown
-
1999
- 1999-10-27 HK HK99104833.5A patent/HK1020671A1/xx not_active IP Right Cessation
-
2008
- 2008-09-04 JP JP2008227311A patent/JP2009019057A/ja not_active Withdrawn
-
2013
- 2013-06-04 JP JP2013118034A patent/JP2013166797A/ja not_active Withdrawn
-
2015
- 2015-06-09 JP JP2015116526A patent/JP6095725B2/ja not_active Expired - Lifetime
-
2016
- 2016-03-23 JP JP2016059108A patent/JP6095821B2/ja not_active Expired - Lifetime
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