TR199801041T2 - Kanabinoid reseptör afinitesine sahip olan 3-pirazolkarboksamid türevleri. - Google Patents

Kanabinoid reseptör afinitesine sahip olan 3-pirazolkarboksamid türevleri.

Info

Publication number
TR199801041T2
TR199801041T2 TR1998/01041T TR9801041T TR199801041T2 TR 199801041 T2 TR199801041 T2 TR 199801041T2 TR 1998/01041 T TR1998/01041 T TR 1998/01041T TR 9801041 T TR9801041 T TR 9801041T TR 199801041 T2 TR199801041 T2 TR 199801041T2
Authority
TR
Turkey
Prior art keywords
cannabinoid receptor
receptor affinity
compounds
pyrazolecarboxamide derivatives
pyrazolecarboxamide
Prior art date
Application number
TR1998/01041T
Other languages
English (en)
Inventor
Barth Francis
Casellas Pierre
Millan Joseph
Oustric Didier
Rinaldi Murielle
Sarran Martine
Original Assignee
Sanofi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi filed Critical Sanofi
Publication of TR199801041T2 publication Critical patent/TR199801041T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Bu bulus (I) formülünün bilesiklerine, bu bilesiklerin hazirlanmasi için bir isleme ve bu bilesiklerin içinde mevcut olduklari farmasötik bilesimlere iliskindir. Bu bilesikler, periferal kanabinoid reseptörleri için iyi bir afiniteye (çekime) sahiptir.
TR1998/01041T 1995-12-08 1996-12-06 Kanabinoid reseptör afinitesine sahip olan 3-pirazolkarboksamid türevleri. TR199801041T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9514547A FR2742148B1 (fr) 1995-12-08 1995-12-08 Nouveaux derives du pyrazole-3-carboxamide, procede pour leur preparation et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
TR199801041T2 true TR199801041T2 (tr) 1998-08-21

Family

ID=9485291

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/01041T TR199801041T2 (tr) 1995-12-08 1996-12-06 Kanabinoid reseptör afinitesine sahip olan 3-pirazolkarboksamid türevleri.

Country Status (34)

Country Link
US (1) US5925768A (tr)
EP (2) EP0885889A3 (tr)
JP (1) JP3510270B2 (tr)
KR (1) KR100488610B1 (tr)
CN (1) CN1101813C (tr)
AR (1) AR004364A1 (tr)
AT (1) ATE191211T1 (tr)
AU (1) AU718763B2 (tr)
BR (1) BR9611986A (tr)
CA (1) CA2239489C (tr)
CZ (1) CZ294307B6 (tr)
DE (1) DE69607484T2 (tr)
DK (1) DK0868420T3 (tr)
EE (1) EE04674B1 (tr)
ES (1) ES2148820T3 (tr)
FR (1) FR2742148B1 (tr)
GR (1) GR3033626T3 (tr)
HU (1) HUP9901244A3 (tr)
IL (1) IL124801A (tr)
IS (1) IS4765A (tr)
MX (1) MX9804565A (tr)
MY (1) MY115228A (tr)
NO (1) NO310683B1 (tr)
NZ (1) NZ323962A (tr)
PL (1) PL186466B1 (tr)
PT (1) PT868420E (tr)
RU (1) RU2170230C2 (tr)
SI (1) SI0868420T1 (tr)
SK (1) SK283706B6 (tr)
TR (1) TR199801041T2 (tr)
TW (1) TW402594B (tr)
UA (1) UA44913C2 (tr)
WO (1) WO1997021682A1 (tr)
ZA (1) ZA9610299B (tr)

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US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
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Also Published As

Publication number Publication date
AU1101097A (en) 1997-07-03
ZA9610299B (en) 1997-06-18
PL327177A1 (en) 1998-11-23
SK283706B6 (sk) 2003-12-02
WO1997021682A1 (fr) 1997-06-19
BR9611986A (pt) 1999-02-17
HUP9901244A3 (en) 2000-12-28
EP0885889A2 (fr) 1998-12-23
ES2148820T3 (es) 2000-10-16
DE69607484D1 (de) 2000-05-04
EE9800171A (et) 1998-12-15
SI0868420T1 (en) 2000-10-31
EP0868420A1 (fr) 1998-10-07
AU718763B2 (en) 2000-04-20
DE69607484T2 (de) 2000-10-26
IS4765A (is) 1998-06-08
RU2170230C2 (ru) 2001-07-10
CZ177598A3 (cs) 1998-10-14
US5925768A (en) 1999-07-20
TW402594B (en) 2000-08-21
JP2000502080A (ja) 2000-02-22
NO310683B1 (no) 2001-08-13
SK75898A3 (en) 1999-01-11
PT868420E (pt) 2000-08-31
HUP9901244A2 (hu) 1999-08-30
MY115228A (en) 2003-04-30
MX9804565A (es) 1998-09-30
EE04674B1 (et) 2006-08-15
NO982589D0 (no) 1998-06-05
UA44913C2 (uk) 2002-03-15
KR100488610B1 (ko) 2005-09-26
IL124801A0 (en) 1999-01-26
CN1207731A (zh) 1999-02-10
ATE191211T1 (de) 2000-04-15
NO982589L (no) 1998-08-03
EP0868420B1 (fr) 2000-03-29
JP3510270B2 (ja) 2004-03-22
KR19990072004A (ko) 1999-09-27
NZ323962A (en) 1999-05-28
CA2239489C (en) 2006-05-09
CA2239489A1 (en) 1997-06-19
EP0885889A3 (fr) 1999-01-27
FR2742148A1 (fr) 1997-06-13
CN1101813C (zh) 2003-02-19
CZ294307B6 (cs) 2004-11-10
DK0868420T3 (da) 2000-08-21
GR3033626T3 (en) 2000-10-31
AR004364A1 (es) 1998-11-04
FR2742148B1 (fr) 1999-10-22
IL124801A (en) 2004-07-25
PL186466B1 (pl) 2004-01-30

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