NO982589D0 - 3-pyrazolkarboksamid-derivater med cannabinoid reseptor-affinitet - Google Patents

3-pyrazolkarboksamid-derivater med cannabinoid reseptor-affinitet

Info

Publication number
NO982589D0
NO982589D0 NO982589A NO982589A NO982589D0 NO 982589 D0 NO982589 D0 NO 982589D0 NO 982589 A NO982589 A NO 982589A NO 982589 A NO982589 A NO 982589A NO 982589 D0 NO982589 D0 NO 982589D0
Authority
NO
Norway
Prior art keywords
cannabinoid receptor
carboxamide derivatives
receptor affinity
pyrazole carboxamide
pyrazole
Prior art date
Application number
NO982589A
Other languages
English (en)
Other versions
NO982589L (no
NO310683B1 (no
Inventor
Francis Barth
Pierre Casellas
Joseph Millan
Didier Oustric
Murielle Rinaldi
Martine Sarran
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of NO982589D0 publication Critical patent/NO982589D0/no
Publication of NO982589L publication Critical patent/NO982589L/no
Publication of NO310683B1 publication Critical patent/NO310683B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO19982589A 1995-12-08 1998-06-05 3-pyrazol-karboksamid-derivater med cannabinoid reseptor- affinitet, anvendelse derav, farmasöytisk preparat, samtfremgangsmåte for fremstilling NO310683B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9514547A FR2742148B1 (fr) 1995-12-08 1995-12-08 Nouveaux derives du pyrazole-3-carboxamide, procede pour leur preparation et compositions pharmaceutiques les contenant
PCT/FR1996/001953 WO1997021682A1 (fr) 1995-12-08 1996-12-06 Derives de 3-pyrazolecarboxamide avec une affinite pour le recepteur des cannabinoides

Publications (3)

Publication Number Publication Date
NO982589D0 true NO982589D0 (no) 1998-06-05
NO982589L NO982589L (no) 1998-08-03
NO310683B1 NO310683B1 (no) 2001-08-13

Family

ID=9485291

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19982589A NO310683B1 (no) 1995-12-08 1998-06-05 3-pyrazol-karboksamid-derivater med cannabinoid reseptor- affinitet, anvendelse derav, farmasöytisk preparat, samtfremgangsmåte for fremstilling

Country Status (34)

Country Link
US (1) US5925768A (no)
EP (2) EP0868420B1 (no)
JP (1) JP3510270B2 (no)
KR (1) KR100488610B1 (no)
CN (1) CN1101813C (no)
AR (1) AR004364A1 (no)
AT (1) ATE191211T1 (no)
AU (1) AU718763B2 (no)
BR (1) BR9611986A (no)
CA (1) CA2239489C (no)
CZ (1) CZ294307B6 (no)
DE (1) DE69607484T2 (no)
DK (1) DK0868420T3 (no)
EE (1) EE04674B1 (no)
ES (1) ES2148820T3 (no)
FR (1) FR2742148B1 (no)
GR (1) GR3033626T3 (no)
HU (1) HUP9901244A3 (no)
IL (1) IL124801A (no)
IS (1) IS4765A (no)
MX (1) MX9804565A (no)
MY (1) MY115228A (no)
NO (1) NO310683B1 (no)
NZ (1) NZ323962A (no)
PL (1) PL186466B1 (no)
PT (1) PT868420E (no)
RU (1) RU2170230C2 (no)
SI (1) SI0868420T1 (no)
SK (1) SK283706B6 (no)
TR (1) TR199801041T2 (no)
TW (1) TW402594B (no)
UA (1) UA44913C2 (no)
WO (1) WO1997021682A1 (no)
ZA (1) ZA9610299B (no)

Families Citing this family (96)

* Cited by examiner, † Cited by third party
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EP0979228A4 (en) * 1997-03-18 2000-05-03 Smithkline Beecham Corp CANNABINOID RECEPTOR AGONISTS
DE69910373T2 (de) * 1998-05-04 2004-04-01 The University Of Connecticut, Farmington Analgetische und immunomodulierende cannabinoiden
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7897598B2 (en) 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
CN1377261A (zh) 1999-03-22 2002-10-30 免疫力药品有限公司 治疗免疫疾病
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US7119108B1 (en) * 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
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MXPA02005103A (es) 1999-10-18 2003-09-25 Alexipharma Inc Ligandos selectivos del receptor de canabinoide (cb2) perifericos.
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
FR2800372B1 (fr) 1999-11-03 2001-12-07 Sanofi Synthelabo Derives tricycliques d'acide 1-benzylpyrazole-3- carboxylique, leur preparation, les medicaments en contenant
WO2002026728A2 (en) * 2000-09-28 2002-04-04 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
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US8449908B2 (en) 2000-12-22 2013-05-28 Alltranz, Llc Transdermal delivery of cannabidiol
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US5015651A (en) * 1988-01-07 1991-05-14 E. I. Du Pont De Nemours And Company Treatment of hypertension with 1,2,4-angiotensin II antagonists
FR2665898B1 (fr) * 1990-08-20 1994-03-11 Sanofi Derives d'amido-3 pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2692575B1 (fr) * 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2713225B1 (fr) * 1993-12-02 1996-03-01 Sanofi Sa N-pipéridino-3-pyrazolecarboxamide substitué.
FR2714057B1 (fr) * 1993-12-17 1996-03-08 Sanofi Elf Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant.

Also Published As

Publication number Publication date
CZ294307B6 (cs) 2004-11-10
FR2742148A1 (fr) 1997-06-13
NZ323962A (en) 1999-05-28
WO1997021682A1 (fr) 1997-06-19
ES2148820T3 (es) 2000-10-16
GR3033626T3 (en) 2000-10-31
NO982589L (no) 1998-08-03
TW402594B (en) 2000-08-21
HUP9901244A2 (hu) 1999-08-30
PL327177A1 (en) 1998-11-23
EP0885889A2 (fr) 1998-12-23
DE69607484T2 (de) 2000-10-26
CN1207731A (zh) 1999-02-10
ATE191211T1 (de) 2000-04-15
AR004364A1 (es) 1998-11-04
KR100488610B1 (ko) 2005-09-26
EE04674B1 (et) 2006-08-15
EP0885889A3 (fr) 1999-01-27
SI0868420T1 (en) 2000-10-31
EP0868420A1 (fr) 1998-10-07
JP2000502080A (ja) 2000-02-22
EP0868420B1 (fr) 2000-03-29
AU718763B2 (en) 2000-04-20
CN1101813C (zh) 2003-02-19
FR2742148B1 (fr) 1999-10-22
BR9611986A (pt) 1999-02-17
SK283706B6 (sk) 2003-12-02
UA44913C2 (uk) 2002-03-15
NO310683B1 (no) 2001-08-13
SK75898A3 (en) 1999-01-11
HUP9901244A3 (en) 2000-12-28
DE69607484D1 (de) 2000-05-04
IL124801A0 (en) 1999-01-26
US5925768A (en) 1999-07-20
PL186466B1 (pl) 2004-01-30
RU2170230C2 (ru) 2001-07-10
TR199801041T2 (xx) 1998-08-21
CA2239489C (en) 2006-05-09
JP3510270B2 (ja) 2004-03-22
CZ177598A3 (cs) 1998-10-14
KR19990072004A (ko) 1999-09-27
IS4765A (is) 1998-06-08
IL124801A (en) 2004-07-25
MY115228A (en) 2003-04-30
CA2239489A1 (en) 1997-06-19
PT868420E (pt) 2000-08-31
DK0868420T3 (da) 2000-08-21
AU1101097A (en) 1997-07-03
ZA9610299B (en) 1997-06-18
EE9800171A (et) 1998-12-15
MX9804565A (es) 1998-09-30

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