EE04674B1 - 3-prasoolkarboksamiidi derivaadid, mis omavad afiinsust kannabinoidretseptori suhtes - Google Patents

3-prasoolkarboksamiidi derivaadid, mis omavad afiinsust kannabinoidretseptori suhtes

Info

Publication number
EE04674B1
EE04674B1 EE9800171A EE9800171A EE04674B1 EE 04674 B1 EE04674 B1 EE 04674B1 EE 9800171 A EE9800171 A EE 9800171A EE 9800171 A EE9800171 A EE 9800171A EE 04674 B1 EE04674 B1 EE 04674B1
Authority
EE
Estonia
Prior art keywords
razole
cannabinoid receptor
carboxamide derivatives
affecting
derivatives affecting
Prior art date
Application number
EE9800171A
Other languages
English (en)
Estonian (et)
Other versions
EE9800171A (et
Inventor
Barth Francis
Casellas Pierre
Millan Joseph
Oustric Didier
Rinaldi Murielle
Sarran Martine
Original Assignee
Sanofi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi filed Critical Sanofi
Publication of EE9800171A publication Critical patent/EE9800171A/xx
Publication of EE04674B1 publication Critical patent/EE04674B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EE9800171A 1995-12-08 1996-12-06 3-prasoolkarboksamiidi derivaadid, mis omavad afiinsust kannabinoidretseptori suhtes EE04674B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9514547A FR2742148B1 (fr) 1995-12-08 1995-12-08 Nouveaux derives du pyrazole-3-carboxamide, procede pour leur preparation et compositions pharmaceutiques les contenant
PCT/FR1996/001953 WO1997021682A1 (fr) 1995-12-08 1996-12-06 Derives de 3-pyrazolecarboxamide avec une affinite pour le recepteur des cannabinoides

Publications (2)

Publication Number Publication Date
EE9800171A EE9800171A (et) 1998-12-15
EE04674B1 true EE04674B1 (et) 2006-08-15

Family

ID=9485291

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800171A EE04674B1 (et) 1995-12-08 1996-12-06 3-prasoolkarboksamiidi derivaadid, mis omavad afiinsust kannabinoidretseptori suhtes

Country Status (34)

Country Link
US (1) US5925768A (no)
EP (2) EP0885889A3 (no)
JP (1) JP3510270B2 (no)
KR (1) KR100488610B1 (no)
CN (1) CN1101813C (no)
AR (1) AR004364A1 (no)
AT (1) ATE191211T1 (no)
AU (1) AU718763B2 (no)
BR (1) BR9611986A (no)
CA (1) CA2239489C (no)
CZ (1) CZ294307B6 (no)
DE (1) DE69607484T2 (no)
DK (1) DK0868420T3 (no)
EE (1) EE04674B1 (no)
ES (1) ES2148820T3 (no)
FR (1) FR2742148B1 (no)
GR (1) GR3033626T3 (no)
HU (1) HUP9901244A3 (no)
IL (1) IL124801A (no)
IS (1) IS4765A (no)
MX (1) MX9804565A (no)
MY (1) MY115228A (no)
NO (1) NO310683B1 (no)
NZ (1) NZ323962A (no)
PL (1) PL186466B1 (no)
PT (1) PT868420E (no)
RU (1) RU2170230C2 (no)
SI (1) SI0868420T1 (no)
SK (1) SK283706B6 (no)
TR (1) TR199801041T2 (no)
TW (1) TW402594B (no)
UA (1) UA44913C2 (no)
WO (1) WO1997021682A1 (no)
ZA (1) ZA9610299B (no)

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DE69910373T2 (de) * 1998-05-04 2004-04-01 The University Of Connecticut, Farmington Analgetische und immunomodulierende cannabinoiden
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7897598B2 (en) 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
US6274635B1 (en) 1999-03-22 2001-08-14 Immugen Pharmaceuticals Inc. Alkylated resorcinol derivatives for the treatment of immune diseases
CA2387892A1 (en) * 1999-10-18 2001-04-26 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
DE60033834T2 (de) 1999-10-18 2007-11-15 The University Of Connecticut, Farmington Für periphäre cannabinoid-rezeptoren selektive liganden
US7119108B1 (en) * 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US6900236B1 (en) 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
FR2800372B1 (fr) 1999-11-03 2001-12-07 Sanofi Synthelabo Derives tricycliques d'acide 1-benzylpyrazole-3- carboxylique, leur preparation, les medicaments en contenant
AU2002213429A1 (en) * 2000-09-28 2002-04-08 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
AU2001296402A1 (en) * 2000-09-28 2002-04-08 Immugen Pharmaceuticals, Inc. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
US8449908B2 (en) 2000-12-22 2013-05-28 Alltranz, Llc Transdermal delivery of cannabidiol
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DE60237431D1 (de) 2001-01-29 2010-10-07 Univ Connecticut Rezeptor-selektive cannabimimetische aminoalkylindole
US7067539B2 (en) * 2001-02-08 2006-06-27 Schering Corporation Cannabinoid receptor ligands
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JP2005507875A (ja) * 2001-08-31 2005-03-24 ユニバーシティ オブ コネチカット カンナビノイド受容体に作用する新規なピラゾール類似体
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US7071213B2 (en) 2001-11-14 2006-07-04 Schering Corporation Cannabinoid receptor ligands
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FR2856683A1 (fr) * 2003-06-25 2004-12-31 Sanofi Synthelabo Derives de 4-cyanopyrazole-3-carboxamide, leur preparation et leur application en therapeutique
GB0402357D0 (en) * 2004-02-03 2004-03-10 Glaxo Group Ltd Novel compounds
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BRPI0518693A2 (pt) * 2004-11-29 2008-12-02 Warner Lambert Co pirazol [3,4-b]piridinas e indazàis terapÊuticos, bem como composiÇço farmacÊutica e uso dos mesmos
US8853205B2 (en) 2005-01-10 2014-10-07 University Of Connecticut Heteropyrrole analogs acting on cannabinoid receptors
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US5015651A (en) * 1988-01-07 1991-05-14 E. I. Du Pont De Nemours And Company Treatment of hypertension with 1,2,4-angiotensin II antagonists
FR2665898B1 (fr) * 1990-08-20 1994-03-11 Sanofi Derives d'amido-3 pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2713225B1 (fr) * 1993-12-02 1996-03-01 Sanofi Sa N-pipéridino-3-pyrazolecarboxamide substitué.
FR2692575B1 (fr) * 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2714057B1 (fr) * 1993-12-17 1996-03-08 Sanofi Elf Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant.

Also Published As

Publication number Publication date
HUP9901244A3 (en) 2000-12-28
FR2742148B1 (fr) 1999-10-22
NO982589L (no) 1998-08-03
CN1101813C (zh) 2003-02-19
DE69607484T2 (de) 2000-10-26
NO310683B1 (no) 2001-08-13
SK75898A3 (en) 1999-01-11
GR3033626T3 (en) 2000-10-31
KR19990072004A (ko) 1999-09-27
DE69607484D1 (de) 2000-05-04
PL327177A1 (en) 1998-11-23
IL124801A0 (en) 1999-01-26
BR9611986A (pt) 1999-02-17
PT868420E (pt) 2000-08-31
NO982589D0 (no) 1998-06-05
MX9804565A (es) 1998-09-30
IS4765A (is) 1998-06-08
JP3510270B2 (ja) 2004-03-22
TW402594B (en) 2000-08-21
EP0868420B1 (fr) 2000-03-29
IL124801A (en) 2004-07-25
ZA9610299B (en) 1997-06-18
CZ294307B6 (cs) 2004-11-10
EE9800171A (et) 1998-12-15
EP0885889A3 (fr) 1999-01-27
JP2000502080A (ja) 2000-02-22
RU2170230C2 (ru) 2001-07-10
PL186466B1 (pl) 2004-01-30
US5925768A (en) 1999-07-20
DK0868420T3 (da) 2000-08-21
AU718763B2 (en) 2000-04-20
ATE191211T1 (de) 2000-04-15
KR100488610B1 (ko) 2005-09-26
SI0868420T1 (en) 2000-10-31
ES2148820T3 (es) 2000-10-16
CN1207731A (zh) 1999-02-10
EP0885889A2 (fr) 1998-12-23
MY115228A (en) 2003-04-30
CZ177598A3 (cs) 1998-10-14
HUP9901244A2 (hu) 1999-08-30
CA2239489C (en) 2006-05-09
AU1101097A (en) 1997-07-03
CA2239489A1 (en) 1997-06-19
NZ323962A (en) 1999-05-28
SK283706B6 (sk) 2003-12-02
FR2742148A1 (fr) 1997-06-13
UA44913C2 (uk) 2002-03-15
EP0868420A1 (fr) 1998-10-07
AR004364A1 (es) 1998-11-04
TR199801041T2 (xx) 1998-08-21
WO1997021682A1 (fr) 1997-06-19

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