TNSN06086A1 - Solvat acetonique du dimethoxy docetaxel et son procede de preparation - Google Patents

Solvat acetonique du dimethoxy docetaxel et son procede de preparation

Info

Publication number
TNSN06086A1
TNSN06086A1 TNP2006000086A TNSN06086A TNSN06086A1 TN SN06086 A1 TNSN06086 A1 TN SN06086A1 TN P2006000086 A TNP2006000086 A TN P2006000086A TN SN06086 A TNSN06086 A TN SN06086A TN SN06086 A1 TNSN06086 A1 TN SN06086A1
Authority
TN
Tunisia
Prior art keywords
solvat
acetonique
preparation
dimethoxy docetaxel
procede
Prior art date
Application number
TNP2006000086A
Other languages
English (en)
French (fr)
Inventor
Marc-Antoine Perrin
Eric Didier
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34224354&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TNSN06086(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of TNSN06086A1 publication Critical patent/TNSN06086A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TNP2006000086A 2003-09-19 2006-03-17 Solvat acetonique du dimethoxy docetaxel et son procede de preparation TNSN06086A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0311016A FR2859996B1 (fr) 2003-09-19 2003-09-19 Solvat acetonique du dimethoxy docetaxel et son procede de preparation
PCT/FR2004/002344 WO2005028462A1 (fr) 2003-09-19 2004-09-16 Solvat acetonique du dimethoxy docetaxel et son procede de preparation

Publications (1)

Publication Number Publication Date
TNSN06086A1 true TNSN06086A1 (en) 2007-10-03

Family

ID=34224354

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2006000086A TNSN06086A1 (en) 2003-09-19 2006-03-17 Solvat acetonique du dimethoxy docetaxel et son procede de preparation

Country Status (37)

Country Link
US (1) US7241907B2 (OSRAM)
EP (1) EP1667986B1 (OSRAM)
JP (1) JP5010279B2 (OSRAM)
KR (1) KR101123588B1 (OSRAM)
CN (1) CN100429207C (OSRAM)
AR (1) AR045667A1 (OSRAM)
AU (1) AU2004274212B2 (OSRAM)
BE (1) BE2013C036I2 (OSRAM)
BR (1) BRPI0414492A8 (OSRAM)
CA (1) CA2539309A1 (OSRAM)
CR (1) CR8292A (OSRAM)
CY (2) CY1114575T1 (OSRAM)
DK (1) DK1667986T3 (OSRAM)
ES (1) ES2403149T4 (OSRAM)
FR (2) FR2859996B1 (OSRAM)
HR (1) HRP20130322T1 (OSRAM)
HU (1) HUS1300025I1 (OSRAM)
IL (1) IL174240A (OSRAM)
LU (1) LU92172I2 (OSRAM)
MA (1) MA28045A1 (OSRAM)
ME (2) ME00054B (OSRAM)
MX (1) MXPA06002639A (OSRAM)
MY (1) MY136668A (OSRAM)
NO (2) NO335997B1 (OSRAM)
NZ (1) NZ545835A (OSRAM)
PA (1) PA8612401A1 (OSRAM)
PE (1) PE20050870A1 (OSRAM)
PL (1) PL1667986T3 (OSRAM)
PT (1) PT1667986E (OSRAM)
RS (2) RS54614B1 (OSRAM)
RU (1) RU2342373C2 (OSRAM)
SI (1) SI1667986T1 (OSRAM)
TN (1) TNSN06086A1 (OSRAM)
TW (1) TWI382022B (OSRAM)
UA (1) UA87115C2 (OSRAM)
WO (1) WO2005028462A1 (OSRAM)
ZA (1) ZA200602255B (OSRAM)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009533330A (ja) * 2006-03-21 2009-09-17 ドクター レディズ ラボラトリーズ リミテッド ドセタキセルの多形体およびプロセス
US7855591B2 (en) * 2006-06-07 2010-12-21 Atmel Corporation Method and system for providing a charge pump very low voltage applications
US7652522B2 (en) * 2006-09-05 2010-01-26 Atmel Corporation High efficiency low cost bi-directional charge pump circuit for very low voltage applications
US20080176958A1 (en) 2007-01-24 2008-07-24 Insert Therapeutics, Inc. Cyclodextrin-based polymers for therapeutics delivery
FR2926551A1 (fr) * 2008-01-17 2009-07-24 Aventis Pharma Sa Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation
AU2013205442B2 (en) * 2008-01-17 2016-05-12 Aventis Pharma S.A. Crystalline forms of dimethoxy docetaxel and methods for preparing same
JP5588983B2 (ja) 2008-08-11 2014-09-10 ウェルズ ファーゴ バンク ナショナル アソシエイション マルチアームポリマーアルカノエートコンジュゲート
FR2945211A1 (fr) 2009-05-06 2010-11-12 Sanofi Aventis Combinaison antitumorale comprenant la cabazitaxel et la capecitabine
AU2015200149B2 (en) * 2009-10-29 2016-12-01 Aventis Pharma S.A. Novel antitumoral use of cabazitaxel
PT2493466T (pt) * 2009-10-29 2021-03-29 Sanofi Mature Ip Nova utilização antifúngica do cabazitaxel
CA2708489A1 (en) * 2009-10-29 2011-04-29 Aventis Pharma S.A. Use of cabazitaxel and a prednisone or a prednisolone in the treatment of prostate cancer
US20130331443A1 (en) 2010-12-22 2013-12-12 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds
WO2012088445A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
EP2688877B1 (en) 2011-04-12 2017-03-08 Teva Pharmaceuticals International GmbH Solid state forms of cabazitaxel and processes for preparation thereof
WO2013024495A1 (en) * 2011-08-18 2013-02-21 Dr. Reddys Laboratories Limited Pharmaceutical formulations of cabazitaxel
TWI526437B (zh) * 2011-09-09 2016-03-21 台灣神隆股份有限公司 卡巴他賽之結晶型
WO2013072766A2 (en) 2011-10-31 2013-05-23 Scinopharm Taiwan, Ltd. Process for cabazitaxel and intermediates thereof
WO2013065070A1 (en) 2011-11-01 2013-05-10 Fresenius Kabi Encology Ltd. Amorphous form of cabazitaxel and process for its preparation
WO2013080217A2 (en) 2011-11-28 2013-06-06 Fresenius Kabi Oncology Ltd. Crystalline forms of carbazitaxel and process for preparation thereof
JP6025861B2 (ja) 2011-12-13 2016-11-16 アベンティス・ファーマ・ソシエテ・アノニム カバジタキセルの結晶形およびこれを調製するための方法
WO2013111157A1 (en) * 2012-01-03 2013-08-01 Shilpa Medicare Limited Process for preparing amorphous cabazitaxel
EA201491506A1 (ru) * 2012-02-10 2014-12-30 Авентис Фарма С.А. Новое применение кабазитаксела в педиатрии
EP2822932A2 (en) 2012-03-08 2015-01-14 IVAX International GmbH Solid state forms of cabazitaxel and processes for preparation thereof
CN102675257B (zh) * 2012-05-10 2014-07-02 上海金和生物技术有限公司 一种卡巴他赛晶体及其制备方法
CN102746258B (zh) 2012-07-25 2015-02-04 重庆泰濠制药有限公司 卡巴他赛的结晶形式及其制备方法
WO2014022237A1 (en) 2012-07-31 2014-02-06 Yung Shin Pharm. Ind. Co., Ltd. Amorphous cabazitaxel
TWI599373B (zh) 2012-08-15 2017-09-21 永信藥品工業股份有限公司 卡巴利他索（ｃａｂａｚｉｔａｘｅｌ）之穩定醫藥調配物
CN103664836B (zh) * 2012-09-20 2016-04-20 齐鲁制药有限公司 7β,10β-二甲氧基多西紫杉醇氘代丙酮合物的晶型A及其制备方法
WO2014055493A1 (en) 2012-10-02 2014-04-10 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles
CN103804323A (zh) * 2012-11-14 2014-05-21 上海希迈医药科技有限公司 一种卡巴他赛溶剂化物及其制备方法和应用
CN103058960B (zh) * 2012-12-12 2014-12-10 江苏奥赛康药业股份有限公司 卡巴他赛多晶型形式及其制备方法
EP2743264A1 (en) 2012-12-13 2014-06-18 INDENA S.p.A. New crystalline form of cabazitaxel, process for the preparation and pharmaceutical compositions thereof
CN103910698B (zh) * 2012-12-30 2016-01-20 上海医药工业研究院 卡巴他赛丙酮合物及其结晶
CN103910696B (zh) * 2012-12-30 2016-01-20 上海医药工业研究院 卡巴他赛异丙醚合物及其结晶
EP2777691A1 (en) 2013-03-14 2014-09-17 Pharmachemie B.V. Taxoid - Purification of Liquid Excipients
EP2815749A1 (en) 2013-06-20 2014-12-24 IP Gesellschaft für Management mbH Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern
CN104277014A (zh) * 2013-07-04 2015-01-14 北京新天宇科技开发有限公司 二甲氧基多西紫杉醇一丙酮化物的稳定转化物及其结晶形式、以及它们的制备方法
WO2015000165A1 (zh) * 2013-07-04 2015-01-08 北京新天宇科技开发有限公司 二甲氧基多西紫杉醇一丙酮化物的稳定转化物及其结晶形式、以及它们的制备方法
EP2865675A1 (en) * 2013-10-23 2015-04-29 INDENA S.p.A. A crystalline anhydrous form of Cabazitaxel, process for the preparation and pharmaceutical compositions thereof
EP2865674A1 (en) 2013-10-23 2015-04-29 INDENA S.p.A. Crystalline solvate forms of Cabazitaxel
CN103601704B (zh) * 2013-11-22 2015-05-06 石家庄智恒医药科技有限公司 无定形卡巴他赛的制备
WO2016113752A2 (en) 2015-01-12 2016-07-21 Emcure Pharmaceuticals Limited Liquid formulation of cabazitaxel
ES2817331T3 (es) * 2015-02-17 2021-04-07 Univ Erasmus Med Ct Rotterdam Uso del cabazitaxel en el tratamiento del cáncer de próstata
EP3093014A1 (en) 2015-05-13 2016-11-16 Aventis Pharma S.A. Cabazitaxel and its use for treating cancer
US10188626B2 (en) 2015-11-03 2019-01-29 Cipla Limited Stabilized cabazitaxel formulations
MX391156B (es) 2016-11-29 2025-03-21 Ptc Therapeutics Mp Inc Forma polimorfica de sepiapterina.
MA46973A (fr) 2016-11-29 2019-10-09 Censa Pharmaceuticals Inc Polymorphes de sépiaptérine et leurs sels
EP3675863A4 (en) 2017-09-01 2021-01-27 PTC Therapeutics MP, Inc. PHARMACEUTICAL COMPOSITION CONSISTING OF SEPIAPTERIN AND ITS USES
LT3801536T (lt) 2018-05-30 2024-09-25 Ptc Therapeutics Mp, Inc. Sepiapterino vartojimas nevalgius, skirtas panaudoti taikant sepiapterino koncentracijos plazmoje padidinimo būdą
JP7547215B2 (ja) 2018-05-30 2024-09-09 ピーティーシー セラピューティクス エムピー，インコーポレイテッド テトラヒドロビオプテリン血漿曝露を増加させるための組成物及び方法
WO2020249507A1 (en) 2019-06-11 2020-12-17 Indena S.P.A. Anhydrous crystalline form of cabazitaxel, a process for its preparation and pharmaceutical compositions containing it
EP3808345A1 (en) 2019-10-15 2021-04-21 Sanofi Mature IP Cabazitaxel in mcrpc patients previously treated with docetaxel and who failed a prior androgen signaling targeted inhibitor agent
EP3797834A1 (en) 2019-09-25 2021-03-31 Sanofi Mature IP Cabazitaxel in mcrpc patients previously treated with docetaxel and who failed a prior androgen signaling targeted inhibitor agent

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766635A (en) * 1991-06-28 1998-06-16 Rhone-Poulenc Rorer S.A. Process for preparing nanoparticles
FR2722191B1 (fr) * 1994-07-08 1996-08-23 Rhone Poulenc Rorer Sa Procede de preparation du trihydrate du (2r,3s)-3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4-acetoxy2alpha-benzoyloxy-5beta,20epoxy-1,7beta,10beta trihydroxy-9-oxo-tax-11-en-13alpha-yle
DE4425978C1 (de) * 1994-07-22 1995-11-23 Karlsruhe Forschzent Verfahren zur Herstellung keramischer Mikrostrukturen
MA23823A1 (fr) * 1995-03-27 1996-10-01 Aventis Pharma Sa Nouveaux taxoides, leur preparation et les compositions qui les contiennent
FR2745814B1 (fr) * 1996-03-06 1998-04-03 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2771092B1 (fr) 1997-11-18 1999-12-17 Rhone Poulenc Rorer Sa Procede de preparation de derives de la classe des taxoides
EP0982027A1 (en) * 1998-08-17 2000-03-01 Aventis Pharma S.A. Taxoid derivatives for treating abnormal cell proliferation of the brain
US6346543B1 (en) * 1998-08-17 2002-02-12 Aventis Pharma S.A. Use of a taxoid to treat abnormal cell proliferation in the brain
US6136989A (en) * 1998-12-30 2000-10-24 Phytogen Life Sciences, Incorporated Method for high yield and large scale extraction of paclitaxel from paclitaxel-containing material
US5969165A (en) * 1999-01-07 1999-10-19 508037 (Nb) Inc. Isolation and purification of paclitaxel and other related taxanes by industrial preparative low pressure chromatography on a polymeric resin column
IL144976A0 (en) * 1999-05-17 2002-06-30 Bristol Myers Squibb Co A process for the preparation of paclitaxel
CA2468953C (en) * 2001-11-29 2010-05-11 Daiichi Pharmaceutical Co., Ltd. Taxane derivative crystal and method for preparing the same

Also Published As

Publication number Publication date
FR2859996A1 (fr) 2005-03-25
PA8612401A1 (es) 2005-08-04
TW200524891A (en) 2005-08-01
NO20061714L (no) 2006-04-19
RS54614B1 (en) 2016-08-31
JP5010279B2 (ja) 2012-08-29
FR13C0037I2 (fr) 2015-11-20
CY2013016I2 (el) 2018-01-10
KR20060072147A (ko) 2006-06-27
FR13C0037I1 (fr) 2013-09-08
AR045667A1 (es) 2005-11-02
IL174240A (en) 2010-12-30
MEP11708A (en) 2010-06-10
NO335997B1 (no) 2015-04-20
CN1849311A (zh) 2006-10-18
LU92172I2 (fr) 2013-05-21
NO2015013I2 (no) 2015-04-22
PL1667986T3 (pl) 2013-06-28
BE2013C036I2 (OSRAM) 2023-12-14
TWI382022B (zh) 2013-01-11
JP2007505866A (ja) 2007-03-15
FR2859996B1 (fr) 2006-02-03
US7241907B2 (en) 2007-07-10
CA2539309A1 (fr) 2005-03-31
ES2403149T3 (es) 2013-05-14
LU92172I9 (OSRAM) 2019-01-03
ES2403149T4 (es) 2013-06-24
PT1667986E (pt) 2013-04-24
AU2004274212A1 (en) 2005-03-31
RU2342373C2 (ru) 2008-12-27
RS20060189A (en) 2008-06-05
PE20050870A1 (es) 2005-11-21
RU2006113122A (ru) 2006-08-27
HUS1300025I1 (hu) 2016-08-29
AU2004274212B2 (en) 2010-03-04
CN100429207C (zh) 2008-10-29
IL174240A0 (en) 2006-08-01
WO2005028462A1 (fr) 2005-03-31
KR101123588B1 (ko) 2012-03-22
UA87115C2 (ru) 2009-06-25
CY1114575T1 (el) 2016-10-05
MA28045A1 (fr) 2006-07-03
ZA200602255B (en) 2007-07-25
BRPI0414492A (pt) 2006-11-14
EP1667986A1 (fr) 2006-06-14
NO2015013I1 (no) 2015-05-04
EP1667986B1 (fr) 2013-01-16
CR8292A (es) 2008-10-15
HRP20130322T1 (en) 2013-07-31
NZ545835A (en) 2009-10-30
SI1667986T1 (sl) 2013-05-31
BRPI0414492A8 (pt) 2019-01-15
CY2013016I1 (el) 2018-01-10
US20050065138A1 (en) 2005-03-24
MXPA06002639A (es) 2006-06-05
ME00054B (me) 2011-02-10
HK1093340A1 (zh) 2007-03-02
MY136668A (en) 2008-11-28
DK1667986T3 (da) 2013-05-06

Similar Documents

Publication Publication Date Title
TNSN06086A1 (en) Solvat acetonique du dimethoxy docetaxel et son procede de preparation
BR9713620A (pt) Sifão de auto-carga notavelmente para irrigação
BR0015188A (pt) Composições farmacêuticas
TNSN95071A1 (fr) PROCEDE DE PREPARATION DU TRIHYDRATE DU (2R,3S)-3-TERT- BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE DE 4-ACETOXY-2 α - BENZOYLOXY-5 BETA ,20-EPOXY-1,7BETA , 10BETA -TRIHYDROXY-9-OXO-TAX-11-EN-13 α -YLE
DE69827127D1 (de) Mehrwertige impstoffzusammensetzung mit gemischten trägern
CY1113600T1 (el) Θεραπειες συνδυασμου για λεμφωματα β-κυτταρου που περιλαμβανουν χορηγηση anti-cd20 αντισωματος
ATE398117T1 (de) Verbindungen mit antibakteriellen und antiparasitischen eigenschaften
BR9608488A (pt) Uso de derivados da vitamina d4 no tratamento de câncer
BR0316421A (pt) Composição farmacêutica compreendendo micropartìculas de octreotìdeo
SE0004053D0 (sv) N-type calcium channel antagonists for the treatment of pain
EP1105407A4 (en) AMINOSTEROLIC COMPOUNDS AND USES THEREOF
NO20014241D0 (no) C16-umettede FP-selektive prostaglandinanaloger
TNSN96011A1 (fr) PROCEDE DE PREPARATION DU TRIHYDRATE DU (2R, 3S) - 3 - BENZOYLAMINO - 2 - HYDROXY - 3 - PHENYLPROPIONATE DE 4,10 - DIACETOXY - 2 α BENZOYLOXY - 5 BETA , 20 - EPOXY - 1, 7BETA - DIHYDROXY - 9 - OXO-TAX - 11 - EN - 13 α - YLE
DE69815100D1 (de) Zusammensetzungen, die dolastatin-15-analoge in kombination mit taxane und dessen derivaten enthalten
ATE474582T1 (de) Pharmazeutische zusammensetzung enthaltend glucan aus mikroalgen
MA27070A1 (fr) Nouveaux derives de l'isoquinoleine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
BR0008791A (pt) Derivados anticonvulsivos, úteis no tratamento de tremor essencial
ATE272651T1 (de) Verbindungen mit wachstumshormon-freisetzender eigenschaft
BR9901387A (pt) Composições para a cura de polìmero.
BE1014017A3 (fr) Procede de preparation d'un extrait contenant au moins un hydroperoxyde.
SE0102857D0 (sv) N-type calcium channel antagonists for the treatment of pain
ATE275401T1 (de) Herstellung von inogatran-agglomeraten und die verbindung inogatran-anhydrid
IT1304433B1 (it) Macchina per la recisione delle radici del bulbo della piantadell'aglio.
TNSN96157A1 (fr) DIHYDRATE DU (2R, 3S) - 3 - TERT - BUTOXYCARBONYLAMINO - 2 - HYDROXY -3- PHENYLPROPIONATE DE 4,10 BETA - DIACETOXY – 2 α ; - BENZOYLOXY - 5 BETA , 20 - EPOXY -1- HYDROXY - 9- OXO - 19 - NOR - CYCLOPROP [G] TAX - 11 - 13 α ; - YLE, ET SON PROCEDE DE PREPARATION.
GB9908942D0 (en) Process for the preparation CIS-(1S,2R)-indanediol by the microbial direduction of 1,2-indanedione