SU1151193A3 - Способ получени перорального препарата дипиридамола - Google Patents

Способ получени перорального препарата дипиридамола Download PDF

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Publication number
SU1151193A3
SU1151193A3 SU823452105A SU3452105A SU1151193A3 SU 1151193 A3 SU1151193 A3 SU 1151193A3 SU 823452105 A SU823452105 A SU 823452105A SU 3452105 A SU3452105 A SU 3452105A SU 1151193 A3 SU1151193 A3 SU 1151193A3
Authority
SU
USSR - Soviet Union
Prior art keywords
dipyridamole
release
equivalents
mixed
per mole
Prior art date
Application number
SU823452105A
Other languages
English (en)
Russian (ru)
Inventor
Брикль Рольф
Грубер Петер
Шепки Готтфрид
Больцер Герхард
Original Assignee
Др.Карл Томэ Гмбх (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6134913&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SU1151193(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Др.Карл Томэ Гмбх (Фирма) filed Critical Др.Карл Томэ Гмбх (Фирма)
Application granted granted Critical
Publication of SU1151193A3 publication Critical patent/SU1151193A3/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SU823452105A 1981-06-19 1982-06-17 Способ получени перорального препарата дипиридамола SU1151193A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813124090 DE3124090A1 (de) 1981-06-19 1981-06-19 Neue orale dipyridamolformen

Publications (1)

Publication Number Publication Date
SU1151193A3 true SU1151193A3 (ru) 1985-04-15

Family

ID=6134913

Family Applications (1)

Application Number Title Priority Date Filing Date
SU823452105A SU1151193A3 (ru) 1981-06-19 1982-06-17 Способ получени перорального препарата дипиридамола

Country Status (27)

Country Link
US (1) US4427648A (cg-RX-API-DMAC10.html)
EP (1) EP0068191B2 (cg-RX-API-DMAC10.html)
JP (1) JPS5849312A (cg-RX-API-DMAC10.html)
KR (1) KR880001090B1 (cg-RX-API-DMAC10.html)
AR (1) AR228779A1 (cg-RX-API-DMAC10.html)
AT (1) ATE17317T1 (cg-RX-API-DMAC10.html)
AU (1) AU555951B2 (cg-RX-API-DMAC10.html)
CA (1) CA1200496A (cg-RX-API-DMAC10.html)
DD (1) DD202505A5 (cg-RX-API-DMAC10.html)
DE (2) DE3124090A1 (cg-RX-API-DMAC10.html)
DK (1) DK158540C (cg-RX-API-DMAC10.html)
ES (1) ES8304797A1 (cg-RX-API-DMAC10.html)
FI (1) FI80829C (cg-RX-API-DMAC10.html)
GB (1) GB2101484B (cg-RX-API-DMAC10.html)
GR (1) GR76503B (cg-RX-API-DMAC10.html)
HU (1) HU186078B (cg-RX-API-DMAC10.html)
IE (1) IE53543B1 (cg-RX-API-DMAC10.html)
IL (1) IL66075A (cg-RX-API-DMAC10.html)
IN (1) IN158513B (cg-RX-API-DMAC10.html)
MA (1) MA19503A1 (cg-RX-API-DMAC10.html)
MX (1) MX160712A (cg-RX-API-DMAC10.html)
MY (1) MY8700727A (cg-RX-API-DMAC10.html)
NZ (1) NZ201008A (cg-RX-API-DMAC10.html)
PH (1) PH25637A (cg-RX-API-DMAC10.html)
PT (1) PT75077B (cg-RX-API-DMAC10.html)
SU (1) SU1151193A3 (cg-RX-API-DMAC10.html)
ZA (1) ZA824315B (cg-RX-API-DMAC10.html)

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DE3237575A1 (de) * 1982-10-09 1984-04-12 Dr. Karl Thomae Gmbh, 7950 Biberach Neue orale mopidamolformen
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DE3314003A1 (de) * 1983-04-18 1984-10-18 Boehringer Ingelheim KG, 6507 Ingelheim Teilbare tablette mit verzoegerter wirkstofffreigabe und verfahren zu deren herstellung
DE3320582A1 (de) * 1983-06-08 1984-12-13 Dr. Karl Thomae Gmbh, 7950 Biberach Gliquidonhaltige zubereitungsformen und verfahren zu ihrer herstellung
DE3320583A1 (de) * 1983-06-08 1984-12-13 Dr. Karl Thomae Gmbh, 7950 Biberach Neue galenische zubereitungsformen von oralen antidiabetika und verfahren zu ihrer herstellung
JPS6051106A (ja) * 1983-08-31 1985-03-22 Yamanouchi Pharmaceut Co Ltd 塩酸アモスラロ−ル持続性製剤
US4867984A (en) * 1984-11-06 1989-09-19 Nagin K. Patel Drug in bead form and process for preparing same
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JPH0674206B2 (ja) * 1989-12-28 1994-09-21 田辺製薬株式会社 放出制御型製剤およびその製法
US5364646A (en) * 1990-01-10 1994-11-15 Dr. Karl Thomae Gmbh Oral pharmaceutical forms of pimobendan
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DK0585355T3 (da) * 1991-05-20 1995-06-06 Tanabe Seiyaku Co Flerlagspræparat med reguleret frigivelse
US5302393A (en) * 1991-07-11 1994-04-12 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Method for inhibiting biological degradation of implantation polymeric material, inhibitor thereof and implantation polymeric material containing the inhibitor
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EP1093814A1 (en) * 1999-10-22 2001-04-25 Boehringer Ingelheim Pharma KG Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders
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JP4331930B2 (ja) * 2001-10-17 2009-09-16 武田薬品工業株式会社 酸に不安定な薬物の高含量顆粒
US20030181488A1 (en) * 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
JP2006516593A (ja) * 2003-02-07 2006-07-06 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Mmp−9依存性疾患の治療及び予防のためのジピリダモール又はモピダモールの使用
DE10306179A1 (de) 2003-02-13 2004-08-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe
JP2006524203A (ja) 2003-04-24 2006-10-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング トロンビンの過剰形成及び/又はトロンビンレセプターの発現上昇により生じる血栓塞栓性疾病及び疾患の治療及び予防のためのジピリダモール又はモピダモールの使用
DE10339862A1 (de) * 2003-08-29 2005-03-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)- phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester-Methansulfonat und dessen Verwendung als Arzneimittel
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
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US20090048173A1 (en) * 2004-05-13 2009-02-19 Wolfgang Eisert Use Of Dipyridamole For Treatment Of Resistance To Platelet Inhibitors
BG860Y1 (bg) * 2004-09-17 2007-02-28 "Софарма" Ад Лекарствена форма на дипиридамол
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US20070087056A1 (en) * 2005-08-09 2007-04-19 Claudia Guthmann Pharmaceutical form with sustained pH-independent active ingredient release for active ingredients having strong pH-dependent solubility
RU2442574C2 (ru) * 2005-08-22 2012-02-20 Новартис Аг ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, СОДЕРЖАЩИЕ pН-ЗАВИСИМОЕ ЛЕКАРСТВЕННОЕ СРЕДСТВО, МОДИФИКАТОР pН И ЗАМЕДЛЯЮЩИЙ АГЕНТ
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Also Published As

Publication number Publication date
KR880001090B1 (ko) 1988-06-23
JPH0251402B2 (cg-RX-API-DMAC10.html) 1990-11-07
HU186078B (en) 1985-05-28
DK158540C (da) 1990-11-12
DD202505A5 (de) 1983-09-21
EP0068191B1 (de) 1986-01-08
GR76503B (cg-RX-API-DMAC10.html) 1984-08-10
GB2101484A (en) 1983-01-19
DK269682A (da) 1982-12-20
AU555951B2 (en) 1986-10-16
FI822173L (fi) 1982-12-20
FI80829C (fi) 1990-08-10
EP0068191A2 (de) 1983-01-05
NZ201008A (en) 1985-11-08
MA19503A1 (fr) 1982-12-31
EP0068191A3 (en) 1983-08-10
DE3124090C2 (cg-RX-API-DMAC10.html) 1991-11-21
CA1200496A (en) 1986-02-11
ES513235A0 (es) 1983-03-16
KR840000229A (ko) 1984-02-18
GB2101484B (en) 1984-09-19
FI80829B (fi) 1990-04-30
ES8304797A1 (es) 1983-03-16
AR228779A1 (es) 1983-04-15
FI822173A0 (fi) 1982-06-17
MX160712A (es) 1990-04-23
IL66075A0 (en) 1982-09-30
JPS5849312A (ja) 1983-03-23
US4427648A (en) 1984-01-24
EP0068191B2 (de) 1991-09-11
IE821453L (en) 1982-12-19
DK158540B (da) 1990-06-05
PH25637A (en) 1991-08-21
AU8496582A (en) 1982-12-23
PT75077A (de) 1982-07-01
IN158513B (cg-RX-API-DMAC10.html) 1986-11-29
MY8700727A (en) 1987-12-31
DE3124090A1 (de) 1983-01-05
ATE17317T1 (de) 1986-01-15
ZA824315B (en) 1984-02-29
DE3268380D1 (en) 1986-02-20
IL66075A (en) 1985-09-29
PT75077B (de) 1985-05-31
IE53543B1 (en) 1988-12-07

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