SMT201500322B - Derivati di tieno[2,3-d]pirimidina e loro uso per trattare l'aritmia - Google Patents

Derivati di tieno[2,3-d]pirimidina e loro uso per trattare l'aritmia

Info

Publication number
SMT201500322B
SMT201500322B SM201500322T SM201500322T SMT201500322B SM T201500322 B SMT201500322 B SM T201500322B SM 201500322 T SM201500322 T SM 201500322T SM 201500322 T SM201500322 T SM 201500322T SM T201500322 B SMT201500322 B SM T201500322B
Authority
SM
San Marino
Prior art keywords
arithmia
tenue
pyrimidine
treat
derivatives
Prior art date
Application number
SM201500322T
Other languages
English (en)
Italian (it)
Inventor
Derek Edward John
John Ford
Original Assignee
Xention Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44071904&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT201500322(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xention Ltd filed Critical Xention Ltd
Publication of SMT201500322B publication Critical patent/SMT201500322B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SM201500322T 2011-04-01 2015-12-22 Derivati di tieno[2,3-d]pirimidina e loro uso per trattare l'aritmia SMT201500322B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1105659.5A GB201105659D0 (en) 2011-04-01 2011-04-01 Compounds
PCT/GB2012/050710 WO2012131379A1 (en) 2011-04-01 2012-03-29 Thieno [2, 3 -d] pyrimidine derivatives and their use to treat arrhythmia

Publications (1)

Publication Number Publication Date
SMT201500322B true SMT201500322B (it) 2016-02-25

Family

ID=44071904

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201500322T SMT201500322B (it) 2011-04-01 2015-12-22 Derivati di tieno[2,3-d]pirimidina e loro uso per trattare l'aritmia

Country Status (42)

Country Link
US (1) US9249155B2 (enExample)
EP (1) EP2694518B1 (enExample)
JP (1) JP5826374B2 (enExample)
KR (1) KR20140023332A (enExample)
CN (1) CN103492392B (enExample)
AP (1) AP2013007198A0 (enExample)
AR (1) AR088735A1 (enExample)
AU (1) AU2012235882B2 (enExample)
BR (1) BR112013025236A2 (enExample)
CA (1) CA2831493A1 (enExample)
CL (1) CL2013002789A1 (enExample)
CO (1) CO6801756A2 (enExample)
CR (1) CR20130488A (enExample)
CU (1) CU24173B1 (enExample)
CY (1) CY1117025T1 (enExample)
DK (1) DK2694518T3 (enExample)
EA (1) EA201301111A1 (enExample)
EC (1) ECSP13012988A (enExample)
ES (1) ES2558563T3 (enExample)
GB (1) GB201105659D0 (enExample)
GT (1) GT201300225A (enExample)
HR (1) HRP20151340T1 (enExample)
HU (1) HUE028438T2 (enExample)
IL (1) IL228555A0 (enExample)
MA (1) MA35064B1 (enExample)
ME (1) ME02314B (enExample)
MX (1) MX335937B (enExample)
NI (1) NI201300100A (enExample)
PE (1) PE20141021A1 (enExample)
PH (1) PH12013501952A1 (enExample)
PL (1) PL2694518T3 (enExample)
PT (1) PT2694518E (enExample)
RS (1) RS54458B1 (enExample)
RU (1) RU2013148627A (enExample)
SG (1) SG193578A1 (enExample)
SI (1) SI2694518T1 (enExample)
SM (1) SMT201500322B (enExample)
TN (1) TN2013000377A1 (enExample)
TW (1) TWI516265B (enExample)
UA (1) UA110131C2 (enExample)
WO (1) WO2012131379A1 (enExample)
ZA (1) ZA201307085B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150307532A1 (en) * 2012-11-20 2015-10-29 The Royal Institution For The Advancement Of Learning/Mcgill University Thienopyrimidine inhibitors of farnesyl and/or geranylgeranyl pyrophosphate synthase
SG11201804901WA (en) 2015-12-22 2018-07-30 SHY Therapeutics LLC Compounds for the treatment of cancer and inflammatory disease
CN106727587A (zh) * 2016-11-28 2017-05-31 李娜 一种治疗心律失常的药物组合物
CA3066939A1 (en) * 2017-06-21 2018-12-27 SHY Therapeutics LLC Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
WO2020132071A1 (en) 2018-12-19 2020-06-25 Shy Therapeutics. Llc Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and f1brotic disease

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Also Published As

Publication number Publication date
CO6801756A2 (es) 2013-11-29
EP2694518B1 (en) 2015-10-07
PT2694518E (pt) 2016-02-05
US9249155B2 (en) 2016-02-02
CU20130124A7 (es) 2014-01-29
CL2013002789A1 (es) 2014-07-18
GT201300225A (es) 2014-12-30
PE20141021A1 (es) 2014-08-30
EA201301111A1 (ru) 2014-02-28
CU24173B1 (es) 2016-04-25
PL2694518T3 (pl) 2016-03-31
TW201244720A (en) 2012-11-16
CY1117025T1 (el) 2017-04-05
AR088735A1 (es) 2014-07-02
AU2012235882A1 (en) 2013-05-02
SI2694518T1 (sl) 2016-02-29
RU2013148627A (ru) 2015-05-10
TN2013000377A1 (en) 2015-01-20
CR20130488A (es) 2013-12-06
AU2012235882B2 (en) 2015-08-06
JP5826374B2 (ja) 2015-12-02
ME02314B (me) 2016-06-20
EP2694518A1 (en) 2014-02-12
CA2831493A1 (en) 2012-10-04
MX2013011301A (es) 2014-04-16
HUE028438T2 (en) 2017-02-28
BR112013025236A2 (pt) 2019-09-24
SG193578A1 (en) 2013-10-30
DK2694518T3 (en) 2015-11-09
KR20140023332A (ko) 2014-02-26
TWI516265B (zh) 2016-01-11
WO2012131379A1 (en) 2012-10-04
US20140206703A1 (en) 2014-07-24
AP2013007198A0 (en) 2013-10-31
NI201300100A (es) 2014-01-07
MA35064B1 (fr) 2014-04-03
HK1193806A1 (zh) 2014-10-03
CN103492392A (zh) 2014-01-01
PH12013501952A1 (en) 2018-04-11
ECSP13012988A (es) 2013-12-31
RS54458B1 (sr) 2016-06-30
IL228555A0 (en) 2013-12-31
JP2014509637A (ja) 2014-04-21
ES2558563T3 (es) 2016-02-05
HRP20151340T1 (hr) 2016-02-26
HK1193096A1 (zh) 2014-09-12
CN103492392B (zh) 2015-11-25
ZA201307085B (en) 2015-04-29
MX335937B (es) 2016-01-04
GB201105659D0 (en) 2011-05-18
NZ615621A (en) 2015-01-30
UA110131C2 (ru) 2015-11-25

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