CL2013002789A1 - El compuesto (2-hidroxi-etil)-amida del ácido 1-{5-fenil-4-[(piridin-2-ilmetil)-amino]-tieno[2,3-d]pirimidin-2-il}-piperidin-3-carboxilico, inhibidor del canal de potasio; composicion farmaceutica; y su uso en el tratamiento o la prevencion de la arritmias. - Google Patents

El compuesto (2-hidroxi-etil)-amida del ácido 1-{5-fenil-4-[(piridin-2-ilmetil)-amino]-tieno[2,3-d]pirimidin-2-il}-piperidin-3-carboxilico, inhibidor del canal de potasio; composicion farmaceutica; y su uso en el tratamiento o la prevencion de la arritmias.

Info

Publication number
CL2013002789A1
CL2013002789A1 CL2013002789A CL2013002789A CL2013002789A1 CL 2013002789 A1 CL2013002789 A1 CL 2013002789A1 CL 2013002789 A CL2013002789 A CL 2013002789A CL 2013002789 A CL2013002789 A CL 2013002789A CL 2013002789 A1 CL2013002789 A1 CL 2013002789A1
Authority
CL
Chile
Prior art keywords
thieno
arrhythmias
pyrimidin
ylmethyl
pyridin
Prior art date
Application number
CL2013002789A
Other languages
English (en)
Inventor
Derek Edward John
John Ford
Original Assignee
Xention Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44071904&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2013002789(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xention Ltd filed Critical Xention Ltd
Publication of CL2013002789A1 publication Critical patent/CL2013002789A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CL2013002789A 2011-04-01 2013-09-27 El compuesto (2-hidroxi-etil)-amida del ácido 1-{5-fenil-4-[(piridin-2-ilmetil)-amino]-tieno[2,3-d]pirimidin-2-il}-piperidin-3-carboxilico, inhibidor del canal de potasio; composicion farmaceutica; y su uso en el tratamiento o la prevencion de la arritmias. CL2013002789A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1105659.5A GB201105659D0 (en) 2011-04-01 2011-04-01 Compounds

Publications (1)

Publication Number Publication Date
CL2013002789A1 true CL2013002789A1 (es) 2014-07-18

Family

ID=44071904

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013002789A CL2013002789A1 (es) 2011-04-01 2013-09-27 El compuesto (2-hidroxi-etil)-amida del ácido 1-{5-fenil-4-[(piridin-2-ilmetil)-amino]-tieno[2,3-d]pirimidin-2-il}-piperidin-3-carboxilico, inhibidor del canal de potasio; composicion farmaceutica; y su uso en el tratamiento o la prevencion de la arritmias.

Country Status (42)

Country Link
US (1) US9249155B2 (es)
EP (1) EP2694518B1 (es)
JP (1) JP5826374B2 (es)
KR (1) KR20140023332A (es)
CN (1) CN103492392B (es)
AP (1) AP2013007198A0 (es)
AR (1) AR088735A1 (es)
AU (1) AU2012235882B2 (es)
BR (1) BR112013025236A2 (es)
CA (1) CA2831493A1 (es)
CL (1) CL2013002789A1 (es)
CO (1) CO6801756A2 (es)
CR (1) CR20130488A (es)
CU (1) CU24173B1 (es)
CY (1) CY1117025T1 (es)
DK (1) DK2694518T3 (es)
EA (1) EA201301111A1 (es)
EC (1) ECSP13012988A (es)
ES (1) ES2558563T3 (es)
GB (1) GB201105659D0 (es)
GT (1) GT201300225A (es)
HK (2) HK1193096A1 (es)
HR (1) HRP20151340T1 (es)
HU (1) HUE028438T2 (es)
IL (1) IL228555A0 (es)
MA (1) MA35064B1 (es)
ME (1) ME02314B (es)
MX (1) MX335937B (es)
NI (1) NI201300100A (es)
PE (1) PE20141021A1 (es)
PL (1) PL2694518T3 (es)
PT (1) PT2694518E (es)
RS (1) RS54458B1 (es)
RU (1) RU2013148627A (es)
SG (1) SG193578A1 (es)
SI (1) SI2694518T1 (es)
SM (1) SMT201500322B (es)
TN (1) TN2013000377A1 (es)
TW (1) TWI516265B (es)
UA (1) UA110131C2 (es)
WO (1) WO2012131379A1 (es)
ZA (1) ZA201307085B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150307532A1 (en) * 2012-11-20 2015-10-29 The Royal Institution For The Advancement Of Learning/Mcgill University Thienopyrimidine inhibitors of farnesyl and/or geranylgeranyl pyrophosphate synthase
JP7114076B2 (ja) 2015-12-22 2022-08-08 シャイ・セラピューティクス・エルエルシー がん及び炎症性疾患の処置のための化合物
CN106727587A (zh) * 2016-11-28 2017-05-31 李娜 一种治疗心律失常的药物组合物
MX2019014875A (es) 2017-06-21 2021-01-29 SHY Therapeutics LLC Compuestos que interaccionan con la superfamilia ras para el tratamiento de cancer, enfermedades inflamatorias, rasopatias y enfermedad fibrotica.

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Also Published As

Publication number Publication date
KR20140023332A (ko) 2014-02-26
HK1193096A1 (zh) 2014-09-12
UA110131C2 (ru) 2015-11-25
CU24173B1 (es) 2016-04-25
CR20130488A (es) 2013-12-06
ZA201307085B (en) 2015-04-29
SMT201500322B (it) 2016-02-25
WO2012131379A1 (en) 2012-10-04
HK1193806A1 (zh) 2014-10-03
AR088735A1 (es) 2014-07-02
CN103492392A (zh) 2014-01-01
EP2694518A1 (en) 2014-02-12
ME02314B (me) 2016-06-20
BR112013025236A2 (pt) 2019-09-24
US9249155B2 (en) 2016-02-02
IL228555A0 (en) 2013-12-31
RS54458B1 (en) 2016-06-30
US20140206703A1 (en) 2014-07-24
AU2012235882B2 (en) 2015-08-06
ES2558563T3 (es) 2016-02-05
NZ615621A (en) 2015-01-30
EP2694518B1 (en) 2015-10-07
SI2694518T1 (sl) 2016-02-29
GB201105659D0 (en) 2011-05-18
RU2013148627A (ru) 2015-05-10
TN2013000377A1 (en) 2015-01-20
CO6801756A2 (es) 2013-11-29
NI201300100A (es) 2014-01-07
CN103492392B (zh) 2015-11-25
TW201244720A (en) 2012-11-16
GT201300225A (es) 2014-12-30
CU20130124A7 (es) 2014-01-29
EA201301111A1 (ru) 2014-02-28
CA2831493A1 (en) 2012-10-04
ECSP13012988A (es) 2013-12-31
MX2013011301A (es) 2014-04-16
CY1117025T1 (el) 2017-04-05
AU2012235882A1 (en) 2013-05-02
TWI516265B (zh) 2016-01-11
DK2694518T3 (en) 2015-11-09
PE20141021A1 (es) 2014-08-30
MX335937B (es) 2016-01-04
MA35064B1 (fr) 2014-04-03
PT2694518E (pt) 2016-02-05
SG193578A1 (en) 2013-10-30
HRP20151340T1 (hr) 2016-02-26
AP2013007198A0 (en) 2013-10-31
JP5826374B2 (ja) 2015-12-02
PL2694518T3 (pl) 2016-03-31
JP2014509637A (ja) 2014-04-21
HUE028438T2 (en) 2017-02-28

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