SK99894A3 - Pyrazolopyrimidine derivatives, method of their preparation pharmaceutical agent and use - Google Patents

Pyrazolopyrimidine derivatives, method of their preparation pharmaceutical agent and use Download PDF

Info

Publication number
SK99894A3
SK99894A3 SK998-94A SK99894A SK99894A3 SK 99894 A3 SK99894 A3 SK 99894A3 SK 99894 A SK99894 A SK 99894A SK 99894 A3 SK99894 A3 SK 99894A3
Authority
SK
Slovakia
Prior art keywords
group
formula
compound
lower alkyl
carbon atoms
Prior art date
Application number
SK998-94A
Other languages
English (en)
Slovak (sk)
Inventor
Nicole Bru-Magniez
Timur Gungor
Jean-Marie Teulon
Original Assignee
Upsa Sa Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9202109A external-priority patent/FR2687676B1/fr
Application filed by Upsa Sa Lab filed Critical Upsa Sa Lab
Publication of SK99894A3 publication Critical patent/SK99894A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK998-94A 1992-02-24 1993-02-18 Pyrazolopyrimidine derivatives, method of their preparation pharmaceutical agent and use SK99894A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9202109A FR2687676B1 (fr) 1992-02-24 1992-02-24 Nouveaux derives de polyazaindenes antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant.
FR9205417A FR2687677B1 (fr) 1992-02-24 1992-04-30 Nouveaux derives de polyazaindenes antagonistes des recepteurs a l'angiotensine ii ; leurs procedes de preparation, compositions pharmaceutiques les contenant.
PCT/FR1993/000160 WO1993017023A1 (fr) 1992-02-24 1993-02-18 Derives de pyrazolopyrimidines antagonistes des recepteurs a l'angiotensine ii

Publications (1)

Publication Number Publication Date
SK99894A3 true SK99894A3 (en) 1995-04-12

Family

ID=26229283

Family Applications (2)

Application Number Title Priority Date Filing Date
SK997-94A SK280343B6 (sk) 1992-02-24 1993-02-18 Triazolopyrimidínové deriváty ako antigonisty rece
SK998-94A SK99894A3 (en) 1992-02-24 1993-02-18 Pyrazolopyrimidine derivatives, method of their preparation pharmaceutical agent and use

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SK997-94A SK280343B6 (sk) 1992-02-24 1993-02-18 Triazolopyrimidínové deriváty ako antigonisty rece

Country Status (19)

Country Link
EP (2) EP0628046B1 (et)
JP (2) JP3372040B2 (et)
KR (2) KR100272922B1 (et)
AT (1) ATE179979T1 (et)
AU (2) AU668544B2 (et)
CA (2) CA2128871A1 (et)
CZ (2) CZ204594A3 (et)
DE (1) DE69324910T2 (et)
EE (2) EE03045B1 (et)
ES (1) ES2133390T3 (et)
FI (2) FI943808A (et)
FR (1) FR2687677B1 (et)
HU (2) HU220392B (et)
MD (2) MD553G2 (et)
NZ (2) NZ249509A (et)
RU (1) RU2116308C1 (et)
SK (2) SK280343B6 (et)
TW (2) TW222275B (et)
WO (2) WO1993017023A1 (et)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5389632A (en) * 1992-02-24 1995-02-14 Laboratoires Upsa Pyrazolopyrimidine derivatives which are angiotensin II receptor antagonists
IT1263804B (it) * 1993-01-22 1996-09-03 Luso Farmaco Inst Derivati pirimidinonici fusi con eterocicli azotati ad attivita' a ii antagonista
US5571813A (en) * 1993-06-10 1996-11-05 Beiersdorf-Lilly Gmbh Fused pyrimidine compounds and their use as pharmaceuticals
US20080188494A1 (en) * 2005-04-25 2008-08-07 Basf Aktiengesellschaft Use Of 5-Alkyl-6-Phenylalkyl-7-Aminoazolopyrimidines, Novel Azolopyrimidines, Processes For Their Preparation And Compositions Comprising Them
WO2008003753A1 (en) * 2006-07-07 2008-01-10 Biovitrum Ab (Publ) Pyrazolo [1,5-a] pyrimidine analogs for use as inhibitors of stearoyl-coa desaturase (scd) activity
DE102006039255A1 (de) * 2006-08-17 2008-02-21 Bayer Cropscience Ag Insektizide heterocyclische Carbonsäurederivate
MA33071B1 (fr) * 2009-01-30 2012-02-01 Takeda Pharmaceutical Compose a noyau condenses et son utilisation
JP2013538838A (ja) 2010-09-27 2013-10-17 プロクシマゲン リミテッド ７−ヒドロキシ−ピラゾロ［１，５−ａ］ピリミジン化合物およびｃｃｒ２レセプターアンタゴニストとしてのその使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL94390A (en) * 1989-05-30 1996-03-31 Merck & Co Inc The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them
EP0522038A4 (en) * 1990-03-30 1993-05-26 Merck & Co. Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
FR2678618B1 (fr) * 1991-07-05 1993-11-05 Upsa Laboratoires Nouveaux derives de triazolo pyrimidine antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant.

Also Published As

Publication number Publication date
HU9402429D0 (en) 1994-10-28
AU668544B2 (en) 1996-05-09
KR100272922B1 (ko) 2001-02-01
JP3372040B2 (ja) 2003-01-27
EE03046B1 (et) 1997-10-15
JPH07504177A (ja) 1995-05-11
JPH07504178A (ja) 1995-05-11
WO1993017023A1 (fr) 1993-09-02
FR2687677A1 (fr) 1993-08-27
FI943807A0 (fi) 1994-08-19
DE69324910T2 (de) 1999-10-21
AU668139B2 (en) 1996-04-26
HUT70949A (en) 1995-11-28
FI943808A0 (fi) 1994-08-19
EP0628046A1 (fr) 1994-12-14
NZ249508A (en) 1996-07-26
HUT70953A (en) 1995-11-28
ATE179979T1 (de) 1999-05-15
CA2128876A1 (en) 1993-09-02
RU94040854A (ru) 1996-08-10
KR950700302A (ko) 1995-01-16
TW222275B (et) 1994-04-11
CZ282075B6 (cs) 1997-05-14
MD553G2 (ro) 1996-12-31
NZ249509A (en) 1996-06-25
FI943808A (fi) 1994-10-24
EP0628046B1 (fr) 1999-05-12
DE69324910D1 (de) 1999-06-17
KR950700303A (ko) 1995-01-16
HU220392B (hu) 2002-01-28
HU9402430D0 (en) 1994-10-28
FR2687677B1 (fr) 1996-10-11
CA2128876C (en) 2004-02-03
CA2128871A1 (en) 1993-09-02
FI943807A (fi) 1994-10-24
AU3635793A (en) 1993-09-13
EP0628045A1 (fr) 1994-12-14
MD554F1 (en) 1996-05-31
AU3635893A (en) 1993-09-13
MD554G2 (ro) 1997-01-31
EE03045B1 (et) 1997-10-15
ES2133390T3 (es) 1999-09-16
CZ204494A3 (en) 1994-12-15
WO1993017024A1 (fr) 1993-09-02
MD553F1 (en) 1996-05-31
SK99794A3 (en) 1995-04-12
SK280343B6 (sk) 1999-12-10
RU2116308C1 (ru) 1998-07-27
TW221438B (et) 1994-03-01
CZ204594A3 (en) 1994-12-15

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