MD554F1 - New derivatives of triazolopyrimidine receptors antagonists of angiotensine II, their production and pharmaceutical composition the organic part of which they are - Google Patents
New derivatives of triazolopyrimidine receptors antagonists of angiotensine II, their production and pharmaceutical composition the organic part of which they areInfo
- Publication number
- MD554F1 MD554F1 MD95-0112A MD950112A MD554F1 MD 554 F1 MD554 F1 MD 554F1 MD 950112 A MD950112 A MD 950112A MD 554 F1 MD554 F1 MD 554F1
- Authority
- MD
- Moldova
- Prior art keywords
- angiotensine
- triazolopyrimidine
- production
- pharmaceutical composition
- new derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Inventia se refera la derivatii cu formula si la formele lor tautomere, de asemenea la sarurile lor aditive si la utilizarea lor in terapie, in special, pentru tratamentul si profilaxia afectiunilor cardiovasculare, in particular, pe
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9202109A FR2687676B1 (en) | 1992-02-24 | 1992-02-24 | NOVEL ANGIOTENSIN II RECEPTOR ANTAGONIST POLYAZAINDENES DERIVATIVES; THEIR PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| FR9205417A FR2687677B1 (en) | 1992-02-24 | 1992-04-30 | NOVEL ANGIOTENSIN II RECEPTOR ANTAGONIST POLYAZAINDENES DERIVATIVES; THEIR PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD554F1 true MD554F1 (en) | 1996-05-31 |
| MD554G2 MD554G2 (en) | 1997-01-31 |
Family
ID=26229283
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD95-0085A MD553G2 (en) | 1992-02-24 | 1994-12-30 | New purarolopirimidine derivatives, antagonists of angiotensine II receptors, methods of preparation thereof, pharmaceutical compositions thereof |
| MD95-0112A MD554G2 (en) | 1992-02-24 | 1994-12-30 | New triazolpirimidine derivatives, antagonists of andtomensine II receptors, methods of preparation thereof, pharmaceutical compositions thereof |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD95-0085A MD553G2 (en) | 1992-02-24 | 1994-12-30 | New purarolopirimidine derivatives, antagonists of angiotensine II receptors, methods of preparation thereof, pharmaceutical compositions thereof |
Country Status (19)
| Country | Link |
|---|---|
| EP (2) | EP0628046B1 (en) |
| JP (2) | JPH07504177A (en) |
| KR (2) | KR100272922B1 (en) |
| AT (1) | ATE179979T1 (en) |
| AU (2) | AU668544B2 (en) |
| CA (2) | CA2128871A1 (en) |
| CZ (2) | CZ282075B6 (en) |
| DE (1) | DE69324910T2 (en) |
| EE (2) | EE03045B1 (en) |
| ES (1) | ES2133390T3 (en) |
| FI (2) | FI943808A (en) |
| FR (1) | FR2687677B1 (en) |
| HU (2) | HU220392B (en) |
| MD (2) | MD553G2 (en) |
| NZ (2) | NZ249508A (en) |
| RU (1) | RU2116308C1 (en) |
| SK (2) | SK99894A3 (en) |
| TW (2) | TW222275B (en) |
| WO (2) | WO1993017023A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5389632A (en) * | 1992-02-24 | 1995-02-14 | Laboratoires Upsa | Pyrazolopyrimidine derivatives which are angiotensin II receptor antagonists |
| IT1263804B (en) * | 1993-01-22 | 1996-09-03 | Luso Farmaco Inst | PYRIMIDINONIC DERIVATIVES MELT WITH NITROGEN HETEROCYCLES ACTIVATED IN II ANTAGONIST |
| US5571813A (en) * | 1993-06-10 | 1996-11-05 | Beiersdorf-Lilly Gmbh | Fused pyrimidine compounds and their use as pharmaceuticals |
| WO2006114405A2 (en) * | 2005-04-25 | 2006-11-02 | Basf Aktiengesellschaft | Use of 5-alkyl-6-phenylalkyl-7-amino-azolopyrimidines, novel azolopyrimidines, methods for the production thereof, and agents containing the same |
| WO2008003753A1 (en) * | 2006-07-07 | 2008-01-10 | Biovitrum Ab (Publ) | Pyrazolo [1,5-a] pyrimidine analogs for use as inhibitors of stearoyl-coa desaturase (scd) activity |
| DE102006039255A1 (en) * | 2006-08-17 | 2008-02-21 | Bayer Cropscience Ag | Insecticidal heterocyclic carboxylic acid derivatives |
| MX2011008058A (en) * | 2009-01-30 | 2011-09-01 | Takeda Pharmaceutical | Fused ring compound and use thereof. |
| SG189086A1 (en) | 2010-09-27 | 2013-05-31 | Proximagen Ltd | 7-hydroxy-pyrazolo[1,5-a] pyrimidine compounds and their use as ccr2 receptor antagonists |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL94390A (en) * | 1989-05-30 | 1996-03-31 | Merck & Co Inc | Di-substituted imidazo fused 6-membered nitrogen-containing heterocycles and pharmaceutical compositions containing them |
| EP0522038A4 (en) * | 1990-03-30 | 1993-05-26 | Merck & Co. Inc. | Substituted pyrimidines, pyrimidinones and pyridopyrimidines |
| FR2678618B1 (en) * | 1991-07-05 | 1993-11-05 | Upsa Laboratoires | NOVEL TRIAZOLO PYRIMIDINE DERIVATIVES ANTIAGONISTS OF ANGIOTENSIN II RECEPTORS; THEIR PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
-
1992
- 1992-04-30 FR FR9205417A patent/FR2687677B1/en not_active Expired - Lifetime
-
1993
- 1993-02-18 EP EP93905402A patent/EP0628046B1/en not_active Expired - Lifetime
- 1993-02-18 AU AU36358/93A patent/AU668544B2/en not_active Expired
- 1993-02-18 RU RU94040854A patent/RU2116308C1/en active
- 1993-02-18 JP JP5514580A patent/JPH07504177A/en active Pending
- 1993-02-18 WO PCT/FR1993/000160 patent/WO1993017023A1/en not_active Application Discontinuation
- 1993-02-18 HU HU9402430A patent/HU220392B/en unknown
- 1993-02-18 SK SK998-94A patent/SK99894A3/en unknown
- 1993-02-18 SK SK997-94A patent/SK280343B6/en not_active IP Right Cessation
- 1993-02-18 JP JP51458193A patent/JP3372040B2/en not_active Expired - Lifetime
- 1993-02-18 AT AT93905402T patent/ATE179979T1/en active
- 1993-02-18 CZ CZ942044A patent/CZ282075B6/en not_active IP Right Cessation
- 1993-02-18 NZ NZ249508A patent/NZ249508A/en not_active IP Right Cessation
- 1993-02-18 CA CA002128871A patent/CA2128871A1/en not_active Abandoned
- 1993-02-18 EP EP93905401A patent/EP0628045A1/en not_active Ceased
- 1993-02-18 NZ NZ249509A patent/NZ249509A/en not_active IP Right Cessation
- 1993-02-18 ES ES93905402T patent/ES2133390T3/en not_active Expired - Lifetime
- 1993-02-18 CZ CZ942045A patent/CZ204594A3/en unknown
- 1993-02-18 DE DE69324910T patent/DE69324910T2/en not_active Expired - Lifetime
- 1993-02-18 KR KR1019940702948A patent/KR100272922B1/en not_active IP Right Cessation
- 1993-02-18 HU HU9402429A patent/HUT70953A/en unknown
- 1993-02-18 CA CA002128876A patent/CA2128876C/en not_active Expired - Lifetime
- 1993-02-18 AU AU36357/93A patent/AU668139B2/en not_active Expired
- 1993-02-18 WO PCT/FR1993/000161 patent/WO1993017024A1/en active IP Right Grant
- 1993-02-24 TW TW082101333A patent/TW222275B/zh not_active IP Right Cessation
- 1993-02-24 TW TW082101329A patent/TW221438B/zh not_active IP Right Cessation
-
1994
- 1994-08-19 FI FI943808A patent/FI943808A/en not_active Application Discontinuation
- 1994-08-19 FI FI943807A patent/FI943807A/en not_active Application Discontinuation
- 1994-08-24 KR KR1019940702947A patent/KR950700302A/en not_active Application Discontinuation
- 1994-11-22 EE EE9400440A patent/EE03045B1/en unknown
- 1994-11-22 EE EE9400441A patent/EE03046B1/en unknown
- 1994-12-30 MD MD95-0085A patent/MD553G2/en active IP Right Grant
- 1994-12-30 MD MD95-0112A patent/MD554G2/en active IP Right Grant
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Granted patent for invention | ||
| IF99 | Valid patent on 19990615 |
Free format text: EXPIRES: 20141230 |
|
| MK4A | Patent for invention expired |