MD554F1 - New derivatives of triazolopyrimidine receptors antagonists of angiotensine II, their production and pharmaceutical composition the organic part of which they are - Google Patents

New derivatives of triazolopyrimidine receptors antagonists of angiotensine II, their production and pharmaceutical composition the organic part of which they are

Info

Publication number
MD554F1
MD554F1 MD95-0112A MD950112A MD554F1 MD 554 F1 MD554 F1 MD 554F1 MD 950112 A MD950112 A MD 950112A MD 554 F1 MD554 F1 MD 554F1
Authority
MD
Moldova
Prior art keywords
angiotensine
triazolopyrimidine
production
pharmaceutical composition
new derivatives
Prior art date
Application number
MD95-0112A
Other languages
Romanian (ro)
Other versions
MD554G2 (en
Inventor
Nicole Bru-Magniez
Timur Gungor
Jean-Marie Teulon
Original Assignee
Union Pharma Scient Appl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9202109A external-priority patent/FR2687676B1/en
Application filed by Union Pharma Scient Appl filed Critical Union Pharma Scient Appl
Publication of MD554F1 publication Critical patent/MD554F1/en
Publication of MD554G2 publication Critical patent/MD554G2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Inventia se refera la derivatii cu formula si la formele lor tautomere, de asemenea la sarurile lor aditive si la utilizarea lor in terapie, in special, pentru tratamentul si profilaxia afectiunilor cardiovasculare, in particular, pe
MD95-0112A 1992-02-24 1994-12-30 New triazolpirimidine derivatives, antagonists of andtomensine II receptors, methods of preparation thereof, pharmaceutical compositions thereof MD554G2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9202109A FR2687676B1 (en) 1992-02-24 1992-02-24 NOVEL ANGIOTENSIN II RECEPTOR ANTAGONIST POLYAZAINDENES DERIVATIVES; THEIR PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR9205417A FR2687677B1 (en) 1992-02-24 1992-04-30 NOVEL ANGIOTENSIN II RECEPTOR ANTAGONIST POLYAZAINDENES DERIVATIVES; THEIR PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Publications (2)

Publication Number Publication Date
MD554F1 true MD554F1 (en) 1996-05-31
MD554G2 MD554G2 (en) 1997-01-31

Family

ID=26229283

Family Applications (2)

Application Number Title Priority Date Filing Date
MD95-0085A MD553G2 (en) 1992-02-24 1994-12-30 New purarolopirimidine derivatives, antagonists of angiotensine II receptors, methods of preparation thereof, pharmaceutical compositions thereof
MD95-0112A MD554G2 (en) 1992-02-24 1994-12-30 New triazolpirimidine derivatives, antagonists of andtomensine II receptors, methods of preparation thereof, pharmaceutical compositions thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MD95-0085A MD553G2 (en) 1992-02-24 1994-12-30 New purarolopirimidine derivatives, antagonists of angiotensine II receptors, methods of preparation thereof, pharmaceutical compositions thereof

Country Status (19)

Country Link
EP (2) EP0628046B1 (en)
JP (2) JP3372040B2 (en)
KR (2) KR100272922B1 (en)
AT (1) ATE179979T1 (en)
AU (2) AU668139B2 (en)
CA (2) CA2128871A1 (en)
CZ (2) CZ282075B6 (en)
DE (1) DE69324910T2 (en)
EE (2) EE03045B1 (en)
ES (1) ES2133390T3 (en)
FI (2) FI943808L (en)
FR (1) FR2687677B1 (en)
HU (2) HU220392B (en)
MD (2) MD553G2 (en)
NZ (2) NZ249509A (en)
RU (1) RU2116308C1 (en)
SK (2) SK280343B6 (en)
TW (2) TW222275B (en)
WO (2) WO1993017024A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5389632A (en) * 1992-02-24 1995-02-14 Laboratoires Upsa Pyrazolopyrimidine derivatives which are angiotensin II receptor antagonists
IT1263804B (en) * 1993-01-22 1996-09-03 Luso Farmaco Inst PYRIMIDINONIC DERIVATIVES MELT WITH NITROGEN HETEROCYCLES ACTIVATED IN II ANTAGONIST
US5571813A (en) * 1993-06-10 1996-11-05 Beiersdorf-Lilly Gmbh Fused pyrimidine compounds and their use as pharmaceuticals
GB0013407D0 (en) * 2000-06-02 2000-07-26 Astrazeneca Ab Forms of a chemical compound
TWI334868B (en) * 2003-06-03 2010-12-21 Nippon Kayaku Kk [1,2,4] triazoro [1,5-a] pyrimidine-2-ylurea derivative and use thereof
WO2006114405A2 (en) * 2005-04-25 2006-11-02 Basf Aktiengesellschaft Use of 5-alkyl-6-phenylalkyl-7-amino-azolopyrimidines, novel azolopyrimidines, methods for the production thereof, and agents containing the same
WO2008003753A1 (en) * 2006-07-07 2008-01-10 Biovitrum Ab (Publ) Pyrazolo [1,5-a] pyrimidine analogs for use as inhibitors of stearoyl-coa desaturase (scd) activity
DE102006039255A1 (en) * 2006-08-17 2008-02-21 Bayer Cropscience Ag Insecticidal heterocyclic carboxylic acid derivatives
TWI468410B (en) * 2009-01-30 2015-01-11 Takeda Pharmaceutical Fused ring compound and use thereof
AU2011310713A1 (en) 2010-09-27 2013-04-11 Proximagen Ltd 7-hydroxy-pyrazolo[1,5-a] pyrimidine compounds and their use as CCR2 receptor antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL94390A (en) * 1989-05-30 1996-03-31 Merck & Co Inc Di-substituted imidazo fused 6-membered nitrogen-containing heterocycles and pharmaceutical compositions containing them
WO1991015209A1 (en) * 1990-03-30 1991-10-17 Merck & Co., Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
FR2678618B1 (en) * 1991-07-05 1993-11-05 Upsa Laboratoires NOVEL TRIAZOLO PYRIMIDINE DERIVATIVES ANTIAGONISTS OF ANGIOTENSIN II RECEPTORS; THEIR PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
MD554G2 (en) 1997-01-31
FI943808A7 (en) 1994-10-24
HU9402430D0 (en) 1994-10-28
HU9402429D0 (en) 1994-10-28
CZ204494A3 (en) 1994-12-15
SK99894A3 (en) 1995-04-12
JP3372040B2 (en) 2003-01-27
KR950700303A (en) 1995-01-16
CA2128871A1 (en) 1993-09-02
DE69324910D1 (en) 1999-06-17
HU220392B (en) 2002-01-28
CA2128876C (en) 2004-02-03
EP0628046A1 (en) 1994-12-14
JPH07504177A (en) 1995-05-11
RU94040854A (en) 1996-08-10
ATE179979T1 (en) 1999-05-15
FI943808L (en) 1994-10-24
NZ249509A (en) 1996-06-25
RU2116308C1 (en) 1998-07-27
AU668139B2 (en) 1996-04-26
FI943807A0 (en) 1994-08-19
TW221438B (en) 1994-03-01
EP0628046B1 (en) 1999-05-12
JPH07504178A (en) 1995-05-11
CA2128876A1 (en) 1993-09-02
EE03045B1 (en) 1997-10-15
HUT70949A (en) 1995-11-28
KR100272922B1 (en) 2001-02-01
SK99794A3 (en) 1995-04-12
MD553F1 (en) 1996-05-31
CZ204594A3 (en) 1994-12-15
AU3635893A (en) 1993-09-13
AU668544B2 (en) 1996-05-09
NZ249508A (en) 1996-07-26
WO1993017024A1 (en) 1993-09-02
ES2133390T3 (en) 1999-09-16
KR950700302A (en) 1995-01-16
FR2687677A1 (en) 1993-08-27
SK280343B6 (en) 1999-12-10
FI943808A0 (en) 1994-08-19
TW222275B (en) 1994-04-11
EP0628045A1 (en) 1994-12-14
WO1993017023A1 (en) 1993-09-02
CZ282075B6 (en) 1997-05-14
MD553G2 (en) 1996-12-31
AU3635793A (en) 1993-09-13
EE03046B1 (en) 1997-10-15
FI943807A7 (en) 1994-10-24
DE69324910T2 (en) 1999-10-21
HUT70953A (en) 1995-11-28
FI943807L (en) 1994-10-24
FR2687677B1 (en) 1996-10-11

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Legal Events

Date Code Title Description
FG3A Granted patent for invention
IF99 Valid patent on 19990615

Free format text: EXPIRES: 20141230

MK4A Patent for invention expired