EE03045B1 - Angiotensiin II retseptorite antagonistide pürasolopürimidiinide derivaadid, nende valmistamise meetod ja ravimvormid - Google Patents
Angiotensiin II retseptorite antagonistide pürasolopürimidiinide derivaadid, nende valmistamise meetod ja ravimvormidInfo
- Publication number
- EE03045B1 EE03045B1 EE9400440A EE9400440A EE03045B1 EE 03045 B1 EE03045 B1 EE 03045B1 EE 9400440 A EE9400440 A EE 9400440A EE 9400440 A EE9400440 A EE 9400440A EE 03045 B1 EE03045 B1 EE 03045B1
- Authority
- EE
- Estonia
- Prior art keywords
- angiotensin
- formulations
- preparation
- receptor antagonists
- pyrazolopyrimidine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9202109A FR2687676B1 (fr) | 1992-02-24 | 1992-02-24 | Nouveaux derives de polyazaindenes antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant. |
| FR9205417A FR2687677B1 (fr) | 1992-02-24 | 1992-04-30 | Nouveaux derives de polyazaindenes antagonistes des recepteurs a l'angiotensine ii ; leurs procedes de preparation, compositions pharmaceutiques les contenant. |
| PCT/FR1993/000160 WO1993017023A1 (fr) | 1992-02-24 | 1993-02-18 | Derives de pyrazolopyrimidines antagonistes des recepteurs a l'angiotensine ii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE03045B1 true EE03045B1 (et) | 1997-10-15 |
Family
ID=26229283
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EE9400440A EE03045B1 (et) | 1992-02-24 | 1994-11-22 | Angiotensiin II retseptorite antagonistide pürasolopürimidiinide derivaadid, nende valmistamise meetod ja ravimvormid |
| EE9400441A EE03046B1 (et) | 1992-02-24 | 1994-11-22 | Angiotensiin II retseptorite antagonistide triasolopürimidiinide derivaadid, nende valmistamise meetod ja ravimvormid |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EE9400441A EE03046B1 (et) | 1992-02-24 | 1994-11-22 | Angiotensiin II retseptorite antagonistide triasolopürimidiinide derivaadid, nende valmistamise meetod ja ravimvormid |
Country Status (19)
| Country | Link |
|---|---|
| EP (2) | EP0628046B1 (et) |
| JP (2) | JP3372040B2 (et) |
| KR (2) | KR100272922B1 (et) |
| AT (1) | ATE179979T1 (et) |
| AU (2) | AU668544B2 (et) |
| CA (2) | CA2128871A1 (et) |
| CZ (2) | CZ204594A3 (et) |
| DE (1) | DE69324910T2 (et) |
| EE (2) | EE03045B1 (et) |
| ES (1) | ES2133390T3 (et) |
| FI (2) | FI943808A (et) |
| FR (1) | FR2687677B1 (et) |
| HU (2) | HU220392B (et) |
| MD (2) | MD553G2 (et) |
| NZ (2) | NZ249509A (et) |
| RU (1) | RU2116308C1 (et) |
| SK (2) | SK280343B6 (et) |
| TW (2) | TW222275B (et) |
| WO (2) | WO1993017023A1 (et) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5389632A (en) * | 1992-02-24 | 1995-02-14 | Laboratoires Upsa | Pyrazolopyrimidine derivatives which are angiotensin II receptor antagonists |
| IT1263804B (it) * | 1993-01-22 | 1996-09-03 | Luso Farmaco Inst | Derivati pirimidinonici fusi con eterocicli azotati ad attivita' a ii antagonista |
| US5571813A (en) * | 1993-06-10 | 1996-11-05 | Beiersdorf-Lilly Gmbh | Fused pyrimidine compounds and their use as pharmaceuticals |
| US20080188494A1 (en) * | 2005-04-25 | 2008-08-07 | Basf Aktiengesellschaft | Use Of 5-Alkyl-6-Phenylalkyl-7-Aminoazolopyrimidines, Novel Azolopyrimidines, Processes For Their Preparation And Compositions Comprising Them |
| WO2008003753A1 (en) * | 2006-07-07 | 2008-01-10 | Biovitrum Ab (Publ) | Pyrazolo [1,5-a] pyrimidine analogs for use as inhibitors of stearoyl-coa desaturase (scd) activity |
| DE102006039255A1 (de) * | 2006-08-17 | 2008-02-21 | Bayer Cropscience Ag | Insektizide heterocyclische Carbonsäurederivate |
| MA33071B1 (fr) * | 2009-01-30 | 2012-02-01 | Takeda Pharmaceutical | Compose a noyau condenses et son utilisation |
| JP2013538838A (ja) | 2010-09-27 | 2013-10-17 | プロクシマゲン リミテッド | ７−ヒドロキシ−ピラゾロ［１，５−ａ］ピリミジン化合物およびｃｃｒ２レセプターアンタゴニストとしてのその使用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL94390A (en) * | 1989-05-30 | 1996-03-31 | Merck & Co Inc | The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them |
| EP0522038A4 (en) * | 1990-03-30 | 1993-05-26 | Merck & Co. Inc. | Substituted pyrimidines, pyrimidinones and pyridopyrimidines |
| FR2678618B1 (fr) * | 1991-07-05 | 1993-11-05 | Upsa Laboratoires | Nouveaux derives de triazolo pyrimidine antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant. |
-
1992
- 1992-04-30 FR FR9205417A patent/FR2687677B1/fr not_active Expired - Lifetime
-
1993
- 1993-02-18 CA CA002128871A patent/CA2128871A1/en not_active Abandoned
- 1993-02-18 SK SK997-94A patent/SK280343B6/sk not_active IP Right Cessation
- 1993-02-18 NZ NZ249509A patent/NZ249509A/en not_active IP Right Cessation
- 1993-02-18 AU AU36358/93A patent/AU668544B2/en not_active Expired
- 1993-02-18 EP EP93905402A patent/EP0628046B1/fr not_active Expired - Lifetime
- 1993-02-18 CA CA002128876A patent/CA2128876C/en not_active Expired - Lifetime
- 1993-02-18 CZ CZ942045A patent/CZ204594A3/cs unknown
- 1993-02-18 HU HU9402430A patent/HU220392B/hu unknown
- 1993-02-18 RU RU94040854A patent/RU2116308C1/ru active
- 1993-02-18 SK SK998-94A patent/SK99894A3/sk unknown
- 1993-02-18 WO PCT/FR1993/000160 patent/WO1993017023A1/fr not_active Application Discontinuation
- 1993-02-18 JP JP51458193A patent/JP3372040B2/ja not_active Expired - Lifetime
- 1993-02-18 AU AU36357/93A patent/AU668139B2/en not_active Expired
- 1993-02-18 HU HU9402429A patent/HUT70953A/hu unknown
- 1993-02-18 NZ NZ249508A patent/NZ249508A/en not_active IP Right Cessation
- 1993-02-18 ES ES93905402T patent/ES2133390T3/es not_active Expired - Lifetime
- 1993-02-18 CZ CZ942044A patent/CZ282075B6/cs not_active IP Right Cessation
- 1993-02-18 AT AT93905402T patent/ATE179979T1/de active
- 1993-02-18 DE DE69324910T patent/DE69324910T2/de not_active Expired - Lifetime
- 1993-02-18 WO PCT/FR1993/000161 patent/WO1993017024A1/fr active IP Right Grant
- 1993-02-18 EP EP93905401A patent/EP0628045A1/fr not_active Ceased
- 1993-02-18 JP JP5514580A patent/JPH07504177A/ja active Pending
- 1993-02-18 KR KR1019940702948A patent/KR100272922B1/ko not_active IP Right Cessation
- 1993-02-24 TW TW082101333A patent/TW222275B/zh not_active IP Right Cessation
- 1993-02-24 TW TW082101329A patent/TW221438B/zh not_active IP Right Cessation
-
1994
- 1994-08-19 FI FI943808A patent/FI943808A/fi not_active Application Discontinuation
- 1994-08-19 FI FI943807A patent/FI943807A/fi not_active Application Discontinuation
- 1994-08-24 KR KR1019940702947A patent/KR950700302A/ko not_active Application Discontinuation
- 1994-11-22 EE EE9400440A patent/EE03045B1/et unknown
- 1994-11-22 EE EE9400441A patent/EE03046B1/et unknown
- 1994-12-30 MD MD95-0085A patent/MD553G2/ro active IP Right Grant
- 1994-12-30 MD MD95-0112A patent/MD554G2/ro active IP Right Grant
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO902632D0 (no) | Fremgangsmaate for fremstilling av terapeutisk aktive imidazolyl-alkensyrer. | |
| NO176049C (no) | Analogifremgangsmåte for fremstilling av terapeutiske imidazoler som blokkerer angiotensin-II-reseptorer | |
| CA2072233A1 (en) | Triazolopyrimidine derivatives which are angiotensin ii receptor antagonists; processes for preparing them and pharmaceutical compositions containing them | |
| ATE119524T1 (de) | Substituierte n-(imidazolyl)alkyl-alanin- derivate. | |
| RU94038256A (ru) | Производные пиразолопиримидина, способ их получения, фармацевтические композиции на их основе | |
| EE03045B1 (et) | Angiotensiin II retseptorite antagonistide pürasolopürimidiinide derivaadid, nende valmistamise meetod ja ravimvormid | |
| FI943730A (fi) | Menetelmä angiotensiini-II-antagonistina aktiivisen 3-(2'-N-bentsoyylisulfonamido-bifen-4-yyli)metyyli-5,7-dimetyyli-2-etyyli-3H-imidatso/4,5-b/pyridiinin valmistamiseksi |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB4A | Valid patent at the end of a year |
Effective date: 20021231 |
|
| KB4A | Valid patent at the end of a year |
Effective date: 20031231 |
|
| KB4A | Valid patent at the end of a year |
Effective date: 20041231 |
|
| KB4A | Valid patent at the end of a year |
Effective date: 20051231 |
|
| KB4A | Valid patent at the end of a year |
Effective date: 20061231 |
|
| KB4A | Valid patent at the end of a year |
Effective date: 20071231 |
|
| KB4A | Valid patent at the end of a year |
Effective date: 20081231 |
|
| KB4A | Valid patent at the end of a year |
Effective date: 20091231 |
|
| KB4A | Valid patent at the end of a year |
Effective date: 20101231 |