DE69324910D1 - Triazolopyrimidinderivate als angiotensin-ii rezeptor antagonisten - Google Patents

Triazolopyrimidinderivate als angiotensin-ii rezeptor antagonisten

Info

Publication number
DE69324910D1
DE69324910D1 DE69324910T DE69324910T DE69324910D1 DE 69324910 D1 DE69324910 D1 DE 69324910D1 DE 69324910 T DE69324910 T DE 69324910T DE 69324910 T DE69324910 T DE 69324910T DE 69324910 D1 DE69324910 D1 DE 69324910D1
Authority
DE
Germany
Prior art keywords
angiotensin
receptor antagonists
triazolopyrimidine derivatives
derivatives
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69324910T
Other languages
English (en)
Other versions
DE69324910T2 (de
Inventor
Nicole Bru-Magniez
Timur Guengoer
Jean-Marie Teulon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UNION PHARMA SCIENT APPL
UPSA SAS
Original Assignee
UNION PHARMA SCIENT APPL
UPSA SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9202109A external-priority patent/FR2687676B1/fr
Application filed by UNION PHARMA SCIENT APPL, UPSA SAS filed Critical UNION PHARMA SCIENT APPL
Application granted granted Critical
Publication of DE69324910D1 publication Critical patent/DE69324910D1/de
Publication of DE69324910T2 publication Critical patent/DE69324910T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69324910T 1992-02-24 1993-02-18 Triazolopyrimidinderivate als angiotensin-ii rezeptor antagonisten Expired - Lifetime DE69324910T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9202109A FR2687676B1 (fr) 1992-02-24 1992-02-24 Nouveaux derives de polyazaindenes antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant.
FR9205417A FR2687677B1 (fr) 1992-02-24 1992-04-30 Nouveaux derives de polyazaindenes antagonistes des recepteurs a l'angiotensine ii ; leurs procedes de preparation, compositions pharmaceutiques les contenant.
PCT/FR1993/000161 WO1993017024A1 (fr) 1992-02-24 1993-02-18 Derives de triazolopyrimidines antagonistes des recepteurs a l'angiotensine ii

Publications (2)

Publication Number Publication Date
DE69324910D1 true DE69324910D1 (de) 1999-06-17
DE69324910T2 DE69324910T2 (de) 1999-10-21

Family

ID=26229283

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69324910T Expired - Lifetime DE69324910T2 (de) 1992-02-24 1993-02-18 Triazolopyrimidinderivate als angiotensin-ii rezeptor antagonisten

Country Status (19)

Country Link
EP (2) EP0628046B1 (de)
JP (2) JP3372040B2 (de)
KR (2) KR100272922B1 (de)
AT (1) ATE179979T1 (de)
AU (2) AU668544B2 (de)
CA (2) CA2128871A1 (de)
CZ (2) CZ204594A3 (de)
DE (1) DE69324910T2 (de)
EE (2) EE03045B1 (de)
ES (1) ES2133390T3 (de)
FI (2) FI943808A (de)
FR (1) FR2687677B1 (de)
HU (2) HU220392B (de)
MD (2) MD553G2 (de)
NZ (2) NZ249509A (de)
RU (1) RU2116308C1 (de)
SK (2) SK280343B6 (de)
TW (2) TW222275B (de)
WO (2) WO1993017023A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5389632A (en) * 1992-02-24 1995-02-14 Laboratoires Upsa Pyrazolopyrimidine derivatives which are angiotensin II receptor antagonists
IT1263804B (it) * 1993-01-22 1996-09-03 Luso Farmaco Inst Derivati pirimidinonici fusi con eterocicli azotati ad attivita' a ii antagonista
US5571813A (en) * 1993-06-10 1996-11-05 Beiersdorf-Lilly Gmbh Fused pyrimidine compounds and their use as pharmaceuticals
US20080188494A1 (en) * 2005-04-25 2008-08-07 Basf Aktiengesellschaft Use Of 5-Alkyl-6-Phenylalkyl-7-Aminoazolopyrimidines, Novel Azolopyrimidines, Processes For Their Preparation And Compositions Comprising Them
WO2008003753A1 (en) * 2006-07-07 2008-01-10 Biovitrum Ab (Publ) Pyrazolo [1,5-a] pyrimidine analogs for use as inhibitors of stearoyl-coa desaturase (scd) activity
DE102006039255A1 (de) * 2006-08-17 2008-02-21 Bayer Cropscience Ag Insektizide heterocyclische Carbonsäurederivate
MA33071B1 (fr) * 2009-01-30 2012-02-01 Takeda Pharmaceutical Compose a noyau condenses et son utilisation
JP2013538838A (ja) 2010-09-27 2013-10-17 プロクシマゲン リミテッド ７−ヒドロキシ−ピラゾロ［１，５−ａ］ピリミジン化合物およびｃｃｒ２レセプターアンタゴニストとしてのその使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL94390A (en) * 1989-05-30 1996-03-31 Merck & Co Inc The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them
EP0522038A4 (en) * 1990-03-30 1993-05-26 Merck & Co. Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
FR2678618B1 (fr) * 1991-07-05 1993-11-05 Upsa Laboratoires Nouveaux derives de triazolo pyrimidine antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant.

Also Published As

Publication number Publication date
HU9402429D0 (en) 1994-10-28
AU668544B2 (en) 1996-05-09
KR100272922B1 (ko) 2001-02-01
JP3372040B2 (ja) 2003-01-27
EE03046B1 (et) 1997-10-15
JPH07504177A (ja) 1995-05-11
JPH07504178A (ja) 1995-05-11
WO1993017023A1 (fr) 1993-09-02
FR2687677A1 (fr) 1993-08-27
FI943807A0 (fi) 1994-08-19
DE69324910T2 (de) 1999-10-21
SK99894A3 (en) 1995-04-12
AU668139B2 (en) 1996-04-26
HUT70949A (en) 1995-11-28
FI943808A0 (fi) 1994-08-19
EP0628046A1 (de) 1994-12-14
NZ249508A (en) 1996-07-26
HUT70953A (en) 1995-11-28
ATE179979T1 (de) 1999-05-15
CA2128876A1 (en) 1993-09-02
RU94040854A (ru) 1996-08-10
KR950700302A (ko) 1995-01-16
TW222275B (de) 1994-04-11
CZ282075B6 (cs) 1997-05-14
MD553G2 (ro) 1996-12-31
NZ249509A (en) 1996-06-25
FI943808A (fi) 1994-10-24
EP0628046B1 (de) 1999-05-12
KR950700303A (ko) 1995-01-16
HU220392B (hu) 2002-01-28
HU9402430D0 (en) 1994-10-28
FR2687677B1 (fr) 1996-10-11
CA2128876C (en) 2004-02-03
CA2128871A1 (en) 1993-09-02
FI943807A (fi) 1994-10-24
AU3635793A (en) 1993-09-13
EP0628045A1 (de) 1994-12-14
MD554F1 (en) 1996-05-31
AU3635893A (en) 1993-09-13
MD554G2 (ro) 1997-01-31
EE03045B1 (et) 1997-10-15
ES2133390T3 (es) 1999-09-16
CZ204494A3 (en) 1994-12-15
WO1993017024A1 (fr) 1993-09-02
MD553F1 (en) 1996-05-31
SK99794A3 (en) 1995-04-12
SK280343B6 (sk) 1999-12-10
RU2116308C1 (ru) 1998-07-27
TW221438B (de) 1994-03-01
CZ204594A3 (en) 1994-12-15

Similar Documents

Publication Publication Date Title
NO176049C (no) Analogifremgangsmåte for fremstilling av terapeutiske imidazoler som blokkerer angiotensin-II-reseptorer
NL300006I1 (nl) Imidazolylalkeenzuurderivaten.
ES2062403T3 (es) 5-((tetrazolil)-alquenil)-imidazoles sustituidos.
LV12047A (lv) Kondenseti pirimidina atvasinajumi un to lietosana par angiotenzina II antagonistiem
CA2072233A1 (en) Triazolopyrimidine derivatives which are angiotensin ii receptor antagonists; processes for preparing them and pharmaceutical compositions containing them
ATE119524T1 (de) Substituierte n-(imidazolyl)alkyl-alanin- derivate.
DE69324910D1 (de) Triazolopyrimidinderivate als angiotensin-ii rezeptor antagonisten
FI943730A (fi) Menetelmä angiotensiini-II-antagonistina aktiivisen 3-(2'-N-bentsoyylisulfonamido-bifen-4-yyli)metyyli-5,7-dimetyyli-2-etyyli-3H-imidatso/4,5-b/pyridiinin valmistamiseksi

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
R071 Expiry of right

Ref document number: 628046

Country of ref document: EP