SK83099A3 - Steroids substituted in position 11, method of preparation, application as medicines and pharmaceutical compositions containing them - Google Patents
Steroids substituted in position 11, method of preparation, application as medicines and pharmaceutical compositions containing them Download PDFInfo
- Publication number
- SK83099A3 SK83099A3 SK830-99A SK83099A SK83099A3 SK 83099 A3 SK83099 A3 SK 83099A3 SK 83099 A SK83099 A SK 83099A SK 83099 A3 SK83099 A3 SK 83099A3
- Authority
- SK
- Slovakia
- Prior art keywords
- formula
- compounds
- phenyl
- ethoxy
- carbon atoms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9615829A FR2757519B1 (fr) | 1996-12-23 | 1996-12-23 | Steroides substitues en position 11, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant |
| PCT/FR1997/002379 WO1998028324A1 (fr) | 1996-12-23 | 1997-12-22 | Steroides substitues en position 11, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK83099A3 true SK83099A3 (en) | 2000-01-18 |
Family
ID=9498983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK830-99A SK83099A3 (en) | 1996-12-23 | 1997-12-22 | Steroids substituted in position 11, method of preparation, application as medicines and pharmaceutical compositions containing them |
Country Status (33)
| Country | Link |
|---|---|
| US (3) | US6207657B1 (de) |
| EP (1) | EP0946585B1 (de) |
| JP (1) | JP4376319B2 (de) |
| KR (1) | KR20000062288A (de) |
| CN (1) | CN1247541A (de) |
| AP (1) | AP9901567A0 (de) |
| AR (1) | AR010857A1 (de) |
| AT (1) | ATE216396T1 (de) |
| AU (1) | AU726350B2 (de) |
| BR (1) | BR9714433A (de) |
| CA (1) | CA2275955A1 (de) |
| CZ (1) | CZ227899A3 (de) |
| DE (1) | DE69712095T2 (de) |
| DK (1) | DK0946585T3 (de) |
| EA (1) | EA001868B1 (de) |
| ES (1) | ES2174329T3 (de) |
| FR (1) | FR2757519B1 (de) |
| HR (1) | HRP970711B1 (de) |
| HU (1) | HUP0001447A3 (de) |
| ID (1) | ID22627A (de) |
| IL (1) | IL130509A0 (de) |
| NO (1) | NO313333B1 (de) |
| NZ (1) | NZ336224A (de) |
| PL (1) | PL334124A1 (de) |
| PT (1) | PT946585E (de) |
| SI (1) | SI0946585T1 (de) |
| SK (1) | SK83099A3 (de) |
| TR (1) | TR199901453T2 (de) |
| TW (1) | TW492974B (de) |
| UA (1) | UA54483C2 (de) |
| WO (1) | WO1998028324A1 (de) |
| YU (1) | YU29299A (de) |
| ZA (1) | ZA9711324B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2757519B1 (fr) * | 1996-12-23 | 1999-06-11 | Hoechst Marion Roussel Inc | Steroides substitues en position 11, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant |
| FR2780060B1 (fr) * | 1998-06-23 | 2000-08-04 | Hoechst Marion Roussel Inc | Nouveaux 19-nor steroides 17-halogenes, procede et intermediaires de preparation, application comme medicaments et compositions pharmaceutiques les renfermant |
| DE19929715A1 (de) | 1999-06-24 | 2000-12-28 | Schering Ag | 11ß-langkettig-substituierte Estratriene, Verfahren zur Herstellung , pharmazeutische Präparate, die diese 11ß-langkettig-substituierten Estratriene enthalten, sowie deren Verwendung zur Herstellung von Arzneimitteln |
| FR2826004B1 (fr) * | 2001-06-13 | 2008-03-28 | Aventis Pharma Sa | Procede de preparation de derives estrogenes |
| FR2854402B1 (fr) * | 2003-04-29 | 2008-07-04 | Aventis Pharma Sa | Nouveau procede et intermediaires de preparation de composes 19-nor-steroides |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2640977A2 (en) * | 1982-06-11 | 1990-06-29 | Roussel Uclaf | New position-11 substituted 19-norsteroids and their application as medicinal products. |
| US4859585A (en) * | 1986-04-17 | 1989-08-22 | Trustees Of Tufts College | In-vitro methods for identifying compositions which are agonists and antagonists of estrogens |
| FR2643638B1 (fr) * | 1989-02-24 | 1991-06-14 | Roussel Uclaf | Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant |
| JP3377856B2 (ja) * | 1993-03-25 | 2003-02-17 | イスクラ産業株式会社 | 骨吸収抑制・骨形成促進化合物 |
| DE4329867C1 (de) * | 1993-09-03 | 1994-09-15 | Siemens Ag | Stromspiegel |
| FR2757519B1 (fr) * | 1996-12-23 | 1999-06-11 | Hoechst Marion Roussel Inc | Steroides substitues en position 11, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant |
| FR2757399B1 (fr) * | 1996-12-23 | 1999-12-17 | Hoechst Marion Roussel Inc | Application de composes steroides substitues en 11 pour la fabrication de medicaments ayant une activite estrogene dissociee |
| FR2761992B1 (fr) * | 1997-04-09 | 1999-06-11 | Hoechst Marion Roussel Inc | Nouveaux steroides 4-halogenes, leur procede et intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
| FR2771096B1 (fr) * | 1997-11-17 | 2000-08-11 | Hoechst Marion Roussel Inc | Nouveaux 19-nor steroides, substitues en position 11beta, procede et intermediaires de preparation, application comme medicaments et compositions pharmaceutiques les renfermant |
-
1996
- 1996-12-23 FR FR9615829A patent/FR2757519B1/fr not_active Expired - Fee Related
-
1997
- 1997-12-17 ZA ZA9711324A patent/ZA9711324B/xx unknown
- 1997-12-22 EA EA199900588A patent/EA001868B1/ru not_active IP Right Cessation
- 1997-12-22 SK SK830-99A patent/SK83099A3/sk unknown
- 1997-12-22 PT PT97952972T patent/PT946585E/pt unknown
- 1997-12-22 HU HU0001447A patent/HUP0001447A3/hu unknown
- 1997-12-22 DE DE69712095T patent/DE69712095T2/de not_active Expired - Lifetime
- 1997-12-22 US US09/331,823 patent/US6207657B1/en not_active Expired - Lifetime
- 1997-12-22 YU YU29299A patent/YU29299A/sh unknown
- 1997-12-22 ID IDW990573A patent/ID22627A/id unknown
- 1997-12-22 IL IL13050997A patent/IL130509A0/xx unknown
- 1997-12-22 UA UA99074263A patent/UA54483C2/uk unknown
- 1997-12-22 KR KR1019997005685A patent/KR20000062288A/ko not_active Application Discontinuation
- 1997-12-22 EP EP97952972A patent/EP0946585B1/de not_active Expired - Lifetime
- 1997-12-22 AU AU56678/98A patent/AU726350B2/en not_active Ceased
- 1997-12-22 CA CA002275955A patent/CA2275955A1/fr not_active Abandoned
- 1997-12-22 AP APAP/P/1999/001567A patent/AP9901567A0/en unknown
- 1997-12-22 ES ES97952972T patent/ES2174329T3/es not_active Expired - Lifetime
- 1997-12-22 DK DK97952972T patent/DK0946585T3/da active
- 1997-12-22 BR BR9714433-9A patent/BR9714433A/pt not_active IP Right Cessation
- 1997-12-22 NZ NZ336224A patent/NZ336224A/en unknown
- 1997-12-22 SI SI9730353T patent/SI0946585T1/xx unknown
- 1997-12-22 TR TR1999/01453T patent/TR199901453T2/xx unknown
- 1997-12-22 CZ CZ992278A patent/CZ227899A3/cs unknown
- 1997-12-22 PL PL97334124A patent/PL334124A1/xx unknown
- 1997-12-22 JP JP52847398A patent/JP4376319B2/ja not_active Expired - Fee Related
- 1997-12-22 CN CN97181921A patent/CN1247541A/zh active Pending
- 1997-12-22 AT AT97952972T patent/ATE216396T1/de not_active IP Right Cessation
- 1997-12-22 WO PCT/FR1997/002379 patent/WO1998028324A1/fr not_active Application Discontinuation
- 1997-12-23 AR ARP970106163A patent/AR010857A1/es unknown
- 1997-12-23 HR HR970711A patent/HRP970711B1/xx not_active IP Right Cessation
-
1998
- 1998-02-06 TW TW086119813A patent/TW492974B/zh active
-
1999
- 1999-06-23 NO NO19993125A patent/NO313333B1/no unknown
-
2000
- 2000-06-13 US US09/592,710 patent/US6482813B1/en not_active Expired - Lifetime
-
2002
- 2002-02-14 US US10/075,364 patent/US6541464B2/en not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4959276B2 (ja) | 新規な抗エストロゲンステロイド、ならびに関連の薬学的組成物および使用法 | |
| JP2753562B2 (ja) | 新規な１１−ベンズアルドキシム−エストラ−ジエン誘導体とその製造方法、及びその化合物を含有する医薬製剤 | |
| US20020032180A1 (en) | Novel anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use | |
| JPH07149790A (ja) | 新規な１１−ベンズアルドキシム−１７β−メトキシ−１７α−メトキシメチル−エストラジエン誘導体、その製法およびその物質を含有する医薬製剤 | |
| JP2005539016A (ja) | 女性用受胎調節及びホルモン置換療法のための高められた抗ゴナドトロピン活性を有するプロゲステロン受容体モジュレーター | |
| SK83099A3 (en) | Steroids substituted in position 11, method of preparation, application as medicines and pharmaceutical compositions containing them | |
| DE69806473T2 (de) | Neue 4-halogenierte steroide, ein verfahren und zwischenprodukten zu ihrer herstellung, ihre verwendung als medikamenten und pharmazeutische zusammensetzungen davon | |
| DE69811393T2 (de) | Neue 19-nor 11-beta-substituierte steroide, ein verfahren zu ihrer herstellung sowie zwischenprodukten dieses verfahrens und ihre anwendung als medikamenten | |
| JP4263264B2 (ja) | 解離したエストロゲン活性を有する薬剤を製造するための１１位置換ステロイド化合物の用途 | |
| WO1998028324A9 (fr) | Steroides substitues en position 11, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant | |
| JP4509380B2 (ja) | 新規の１７−ハロゲン化−１９−ノルステロイド、それらの製造方法及び中間体、それらの医薬としての使用並びにそれらを含有する製薬組成物 | |
| MXPA99005841A (en) | Steroids substituted in position 11, method of preparation, application as medicines and pharmaceutical compositions containing them | |
| MXPA00004712A (en) | NOVEL 19-NOR STEROIDS SUBSTITUTED IN POSITION 11&bgr;, PREPARATION METHOD AND INTERMEDIATES, APPLICATION AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |