SK287564B6 - Spôsob zvýšenia výťažku prostriedku obsahujúceho interferón-alfa - Google Patents

Spôsob zvýšenia výťažku prostriedku obsahujúceho interferón-alfa Download PDF

Info

Publication number
SK287564B6
SK287564B6 SK5003-2010A SK50032010A SK287564B6 SK 287564 B6 SK287564 B6 SK 287564B6 SK 50032010 A SK50032010 A SK 50032010A SK 287564 B6 SK287564 B6 SK 287564B6
Authority
SK
Slovakia
Prior art keywords
protein
isoform
pyruvate
attached
interferon
Prior art date
Application number
SK5003-2010A
Other languages
English (en)
Slovak (sk)
Inventor
Susan Cannon-Carlson
Andreas Frei
Seoju Lee
Roland Mengisen
Marcio Voloch
David C. Wylie
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of SK287564B6 publication Critical patent/SK287564B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/56IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SK5003-2010A 1998-11-12 1999-10-05 Spôsob zvýšenia výťažku prostriedku obsahujúceho interferón-alfa SK287564B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19054298A 1998-11-12 1998-11-12
PCT/US1999/020900 WO2000029440A1 (en) 1998-11-12 1999-10-05 Methods of conversion of interferon isoforms and products thereof

Publications (1)

Publication Number Publication Date
SK287564B6 true SK287564B6 (sk) 2011-02-04

Family

ID=22701766

Family Applications (2)

Application Number Title Priority Date Filing Date
SK5003-2010A SK287564B6 (sk) 1998-11-12 1999-10-05 Spôsob zvýšenia výťažku prostriedku obsahujúceho interferón-alfa
SK617-2001A SK287372B6 (sk) 1998-11-12 1999-10-05 Spôsob zvýšenia výťažku prostriedku obsahujúceho interferón-alfa

Family Applications After (1)

Application Number Title Priority Date Filing Date
SK617-2001A SK287372B6 (sk) 1998-11-12 1999-10-05 Spôsob zvýšenia výťažku prostriedku obsahujúceho interferón-alfa

Country Status (27)

Country Link
EP (2) EP1894944B1 (zh)
JP (3) JP4468585B2 (zh)
KR (1) KR100922454B1 (zh)
CN (2) CN101255188A (zh)
AR (1) AR023906A1 (zh)
AT (2) ATE476445T1 (zh)
AU (1) AU766309B2 (zh)
BR (1) BR9915257A (zh)
CA (1) CA2348739C (zh)
CY (2) CY1110444T1 (zh)
CZ (2) CZ303110B6 (zh)
DE (2) DE69942655D1 (zh)
DK (2) DK1894944T3 (zh)
ES (2) ES2315019T3 (zh)
HK (2) HK1112746A1 (zh)
HU (1) HU228265B1 (zh)
ID (1) ID28552A (zh)
IL (2) IL142546A0 (zh)
NO (2) NO329483B1 (zh)
NZ (1) NZ511074A (zh)
PL (2) PL200274B1 (zh)
PT (2) PT1894944E (zh)
SI (2) SI1129111T1 (zh)
SK (2) SK287564B6 (zh)
TW (1) TW577894B (zh)
WO (1) WO2000029440A1 (zh)
ZA (1) ZA200103010B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU228265B1 (en) * 1998-11-12 2013-02-28 Merck Sharp & Dohme Methods of conversion of interferon isoforms and products thereof
WO2010075159A1 (en) 2008-12-23 2010-07-01 Schering Corporation Purification of recombinantly produced interferon
WO2021212220A1 (en) * 2020-04-20 2021-10-28 Altum Pharmaceuticals Inc. Recombinant interferon

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3165463D1 (en) 1980-01-08 1984-09-20 Biogen Nv Dna sequences, recombinant dna molecules and processes for producing human interferon-alpha like polypeptides
US4530901A (en) 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
US4315852A (en) 1980-11-26 1982-02-16 Schering Corporation Extraction of interferon from bacteria
US4364863A (en) * 1980-12-29 1982-12-21 Schering Corporation Extraction of interferon from bacteria
EP0082481B2 (en) 1981-12-23 1990-09-12 Schering Corporation Stabilised alpha-interferon formulations and their preparation
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
US4847079A (en) 1985-07-29 1989-07-11 Schering Corporation Biologically stable interferon compositions comprising thimerosal
US4732683A (en) 1986-12-02 1988-03-22 Biospectrum, Inc. Purification method for alpha interferon
US4765903A (en) 1987-10-06 1988-08-23 Interferon Sciences, Inc. Purification of monomeric interferon
US5272135A (en) 1991-03-01 1993-12-21 Chiron Ophthalmics, Inc. Method for the stabilization of methionine-containing polypeptides
AU648214B2 (en) * 1991-12-31 1994-04-14 Lucky Limited Recombinant gene coding for human alpha interferon and expression vector thereof, etc.
DE69522492T2 (de) * 1994-04-09 2002-05-23 Hoffmann La Roche Verfahren zur Herstellung von Alpha-Interferon
US5766582A (en) 1994-10-11 1998-06-16 Schering Corporation Stable, aqueous alfa interferon solution formulations
HU228265B1 (en) * 1998-11-12 2013-02-28 Merck Sharp & Dohme Methods of conversion of interferon isoforms and products thereof

Also Published As

Publication number Publication date
CY1110444T1 (el) 2015-04-29
CN1326465A (zh) 2001-12-12
KR100922454B1 (ko) 2009-10-21
NZ511074A (en) 2003-10-31
IL142546A (en) 2013-07-31
TW577894B (en) 2004-03-01
CN101255188A (zh) 2008-09-03
DE69939657D1 (de) 2008-11-13
CZ20011303A3 (cs) 2001-08-15
CN100390197C (zh) 2008-05-28
EP1129111A1 (en) 2001-09-05
WO2000029440A1 (en) 2000-05-25
AU6387099A (en) 2000-06-05
EP1129111B1 (en) 2008-10-01
JP4468585B2 (ja) 2010-05-26
ATE476445T1 (de) 2010-08-15
BR9915257A (pt) 2001-08-07
ZA200103010B (en) 2002-07-11
HU228265B1 (en) 2013-02-28
ES2348104T3 (es) 2010-11-30
CY1110794T1 (el) 2015-06-10
ES2315019T3 (es) 2009-03-16
PL201341B1 (pl) 2009-04-30
AR023906A1 (es) 2002-09-04
SK287372B6 (sk) 2010-08-09
PL348162A1 (en) 2002-05-06
NO20100775L (no) 2001-05-11
NO329483B1 (no) 2010-10-25
KR20010080336A (ko) 2001-08-22
JP2010209117A (ja) 2010-09-24
CA2348739C (en) 2010-05-11
PT1129111E (pt) 2008-12-22
NO331699B1 (no) 2012-02-27
EP1894944A1 (en) 2008-03-05
PL200274B1 (pl) 2008-12-31
HK1112746A1 (en) 2008-09-12
DK1129111T3 (da) 2009-01-05
CZ303110B6 (cs) 2012-04-04
DK1894944T3 (da) 2010-10-18
ID28552A (id) 2001-05-31
DE69942655D1 (de) 2010-09-16
JP2002530291A (ja) 2002-09-17
NO20012327L (no) 2001-05-11
ATE409706T1 (de) 2008-10-15
AU766309B2 (en) 2003-10-16
CZ302402B6 (cs) 2011-05-04
NO20012327D0 (no) 2001-05-11
SK6172001A3 (en) 2001-10-08
SI1129111T1 (sl) 2009-06-30
SI1894944T1 (sl) 2010-11-30
CA2348739A1 (en) 2000-05-25
HK1035544A1 (en) 2001-11-30
EP1894944B1 (en) 2010-08-04
IL142546A0 (en) 2002-03-10
HUP0104113A2 (hu) 2002-03-28
JP2006348056A (ja) 2006-12-28
HUP0104113A3 (en) 2004-04-28
PT1894944E (pt) 2010-10-28

Similar Documents

Publication Publication Date Title
AU650893B2 (en) O-glycosylated alpha-2 interferon
US6281337B1 (en) Methods for conversion of protein isoforms
JP2551551B2 (ja) デスルファトヒルジン、その製造及びそれを含む製薬組成物
EP0309050B1 (en) Human insulin-like growth factor analogs with reduced binding to serum carrier proteins and their production in yeast
IL92222A (en) History of insulin, its use and the pharmaceutical preparations containing it
KR100593831B1 (ko) 활성 β-NGF의 제조방법
CA2356779A1 (en) Cytokine receptor chain
Fernley et al. Purification and characterization of a high-M r carbonic anhydrase from sheep parotid gland
SK287564B6 (sk) Spôsob zvýšenia výťažku prostriedku obsahujúceho interferón-alfa
CA1243972A (en) Anti-diabetic compounds
US20090311216A1 (en) Recombinant interferon-beta with enhanced biological activity
EP0092829B1 (en) Process for semi-synthesis of human insulin and alkaline protease for use therein
WO1990005181A1 (de) REINIGUNG VON Cu/Zn-SUPEROXIDDISMUTASE
JP3830179B2 (ja) 抗寄生虫剤
JP2002034590A (ja) 有用タンパク質の製造方法、イヌ疾病の治療剤およびイヌ疾病の治療方法
JPH05219898A (ja) 幼齢動物用飼料

Legal Events

Date Code Title Description
TC4A Change of owner's name

Owner name: MERCK SHARP & DOHME CORP., RAHWAY, NJ, US

Effective date: 20121108

MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20141005