SK287095B6 - Androgénové zlúčeniny, použitie androgénových zlúčenín a súprava s ich obsahom - Google Patents

Androgénové zlúčeniny, použitie androgénových zlúčenín a súprava s ich obsahom Download PDF

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Publication number
SK287095B6
SK287095B6 SK758-2002A SK7582002A SK287095B6 SK 287095 B6 SK287095 B6 SK 287095B6 SK 7582002 A SK7582002 A SK 7582002A SK 287095 B6 SK287095 B6 SK 287095B6
Authority
SK
Slovakia
Prior art keywords
methyl
alkyl
methoxy
product
compounds
Prior art date
Application number
SK758-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK7582002A3 (en
Inventor
Dirk Leysen
Der Louw Jaap Van
Bursi Roberta Buma
Gooyer Marcel Evert De
Original Assignee
N.V. Organon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by N.V. Organon filed Critical N.V. Organon
Publication of SK7582002A3 publication Critical patent/SK7582002A3/sk
Publication of SK287095B6 publication Critical patent/SK287095B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
SK758-2002A 1999-12-02 2000-11-29 Androgénové zlúčeniny, použitie androgénových zlúčenín a súprava s ich obsahom SK287095B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99204080 1999-12-02
PCT/EP2000/012009 WO2001040255A2 (en) 1999-12-02 2000-11-29 14,15-beta-methylene substituted androgens

Publications (2)

Publication Number Publication Date
SK7582002A3 SK7582002A3 (en) 2002-09-10
SK287095B6 true SK287095B6 (sk) 2009-12-07

Family

ID=8240955

Family Applications (1)

Application Number Title Priority Date Filing Date
SK758-2002A SK287095B6 (sk) 1999-12-02 2000-11-29 Androgénové zlúčeniny, použitie androgénových zlúčenín a súprava s ich obsahom

Country Status (27)

Country Link
US (1) US6706700B2 (da)
EP (1) EP1237904B1 (da)
JP (1) JP2003515543A (da)
CN (1) CN1166680C (da)
AR (1) AR026655A1 (da)
AT (1) ATE317396T1 (da)
AU (1) AU778017B2 (da)
CA (1) CA2390226A1 (da)
CO (1) CO5251441A1 (da)
CY (1) CY1106086T1 (da)
CZ (1) CZ301376B6 (da)
DE (1) DE60025958T2 (da)
DK (1) DK1237904T3 (da)
ES (1) ES2258037T3 (da)
HK (1) HK1047596B (da)
HU (1) HUP0203611A3 (da)
IL (1) IL149424A (da)
MX (1) MXPA02004939A (da)
NO (1) NO322422B1 (da)
NZ (1) NZ518753A (da)
PE (1) PE20011033A1 (da)
PL (1) PL202999B1 (da)
RU (1) RU2242479C2 (da)
SK (1) SK287095B6 (da)
TW (1) TWI275593B (da)
WO (1) WO2001040255A2 (da)
ZA (1) ZA200203536B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000059920A2 (en) * 1999-04-06 2000-10-12 Akzo Nobel N.V. Orally active 7.alpha.-alkyl androgens
ES2336439T3 (es) * 2002-01-21 2010-04-13 N.V. Organon Proceso para la preparacion de 7-alfa-metilesteroides.
US20080293683A1 (en) * 2007-05-24 2008-11-27 University Of Kansas Medical Center Hormone Replacement Therapy
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
BR112014008196B8 (pt) * 2011-10-07 2020-12-15 Estetra Sprl processo para a preparação de um composto da fórmula (i)
CA2988485A1 (en) 2015-06-18 2016-12-22 Mithra Pharmaceuticals S.A. Orodispersible tablet containing estetrol
SI3310333T1 (sl) 2015-06-18 2020-08-31 Estetra Sprl Orodisperzibilna enota odmerka, ki vsebuje komponento estetrola
EP3310346B1 (en) 2015-06-18 2021-03-24 Estetra SPRL Orodispersible tablet containing estetrol
KR102664563B1 (ko) 2015-06-18 2024-05-09 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 에스테트롤 성분을 함유하는 구강분해성 투여 단위
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
CN111621141B (zh) * 2020-06-12 2022-04-08 广西大学 一种缓释型二氧化氯-水性聚氨酯抗菌膜及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3086027A (en) * 1960-01-22 1963-04-16 Lilly Co Eli 19-nor-4, 9(10)-steroids and process
IE60780B1 (en) 1987-01-23 1994-08-10 Akzo Nv New 11-aryl steroid derivatives
DE19537626A1 (de) * 1995-10-10 1997-04-17 Jenapharm Gmbh Steroide mit einer 14, 15-Methylengruppe
DE19827522A1 (de) * 1998-06-22 1999-12-23 Jenapharm Gmbh 14,15-Cyclopropanosteroide der 19-Nor-Androstanreihe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
WO2000053619A1 (en) 1999-03-08 2000-09-14 Akzo Nobel N.V. 14.beta., 17-alpha-hydroxymethylandrostane derivatives as androgens

Also Published As

Publication number Publication date
CY1106086T1 (el) 2011-06-08
IL149424A (en) 2007-05-15
EP1237904B1 (en) 2006-02-08
AR026655A1 (es) 2003-02-19
MXPA02004939A (es) 2003-05-23
HUP0203611A3 (en) 2004-07-28
HK1047596B (zh) 2006-04-21
ES2258037T3 (es) 2006-08-16
TWI275593B (en) 2007-03-11
PL355689A1 (en) 2004-05-17
WO2001040255A3 (en) 2001-11-15
SK7582002A3 (en) 2002-09-10
CO5251441A1 (es) 2003-02-28
PE20011033A1 (es) 2001-10-11
CA2390226A1 (en) 2001-06-07
HK1047596A1 (en) 2003-02-28
AU778017B2 (en) 2004-11-11
US6706700B2 (en) 2004-03-16
ATE317396T1 (de) 2006-02-15
JP2003515543A (ja) 2003-05-07
AU2838301A (en) 2001-06-12
ZA200203536B (en) 2003-08-04
PL202999B1 (pl) 2009-08-31
EP1237904A2 (en) 2002-09-11
NO20022564L (no) 2002-05-30
RU2242479C2 (ru) 2004-12-20
CZ20021894A3 (cs) 2002-08-14
DK1237904T3 (da) 2006-06-06
CZ301376B6 (cs) 2010-02-03
CN1166680C (zh) 2004-09-15
WO2001040255A2 (en) 2001-06-07
IL149424A0 (en) 2002-11-10
NO322422B1 (no) 2006-10-02
DE60025958D1 (de) 2006-04-20
HUP0203611A2 (hu) 2003-03-28
NZ518753A (en) 2004-05-28
US20030100543A1 (en) 2003-05-29
CN1402735A (zh) 2003-03-12
DE60025958T2 (de) 2006-07-27
NO20022564D0 (no) 2002-05-30

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US20040059140A1 (en) 14(15)-unsaturated 15- and/or 16-substituted androgens with mixed androgen-progrestational profile
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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20101129