CY1106086T1 - Υποκαθισταμενα 14,15-βητα-μεθυλικα ανδρογονα - Google Patents
Υποκαθισταμενα 14,15-βητα-μεθυλικα ανδρογοναInfo
- Publication number
- CY1106086T1 CY1106086T1 CY20061100500T CY061100500T CY1106086T1 CY 1106086 T1 CY1106086 T1 CY 1106086T1 CY 20061100500 T CY20061100500 T CY 20061100500T CY 061100500 T CY061100500 T CY 061100500T CY 1106086 T1 CY1106086 T1 CY 1106086T1
- Authority
- CY
- Cyprus
- Prior art keywords
- methylon
- androgens
- beta
- substituted
- preparation
- Prior art date
Links
- 239000003098 androgen Substances 0.000 title 1
- 229940030486 androgens Drugs 0.000 title 1
- 150000003431 steroids Chemical class 0.000 abstract 2
- 206010002261 Androgen deficiency Diseases 0.000 abstract 1
- 230000001548 androgenic effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fodder In General (AREA)
Abstract
Η εφεύρεση που αποκαλύπτεται σχετίζεται με το αναπάντεχο εύρημα νέων στεροειδών τα οποία χαρακτηρίζονται από ένα 14β,15β-κυκλοπροπανικό δακτύλιο και μια 17α υδροξυμεθυλική ομάδα. Αυτά τα στεροειδή σύμφωνα με την εφεύρεση βρέθηκαν να έχουν κοινό μια ανδρογόνο δράση. Μπορούν να χρησιμοποιούνται για την παρασκευή μιας ουσίας για ανδρική αντισύλληψη, καθώς επίσης για την παρασκευή ενός φαρμάκου για τη θεραπεία της ανεπάρκειας ανδρογόνου.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99204080 | 1999-12-02 | ||
PCT/EP2000/012009 WO2001040255A2 (en) | 1999-12-02 | 2000-11-29 | 14,15-beta-methylene substituted androgens |
EP00993259A EP1237904B1 (en) | 1999-12-02 | 2000-11-29 | 14,15-beta-methylene substituted androgens |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1106086T1 true CY1106086T1 (el) | 2011-06-08 |
Family
ID=8240955
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20061100500T CY1106086T1 (el) | 1999-12-02 | 2006-04-10 | Υποκαθισταμενα 14,15-βητα-μεθυλικα ανδρογονα |
Country Status (27)
Country | Link |
---|---|
US (1) | US6706700B2 (el) |
EP (1) | EP1237904B1 (el) |
JP (1) | JP2003515543A (el) |
CN (1) | CN1166680C (el) |
AR (1) | AR026655A1 (el) |
AT (1) | ATE317396T1 (el) |
AU (1) | AU778017B2 (el) |
CA (1) | CA2390226A1 (el) |
CO (1) | CO5251441A1 (el) |
CY (1) | CY1106086T1 (el) |
CZ (1) | CZ301376B6 (el) |
DE (1) | DE60025958T2 (el) |
DK (1) | DK1237904T3 (el) |
ES (1) | ES2258037T3 (el) |
HK (1) | HK1047596B (el) |
HU (1) | HUP0203611A3 (el) |
IL (1) | IL149424A (el) |
MX (1) | MXPA02004939A (el) |
NO (1) | NO322422B1 (el) |
NZ (1) | NZ518753A (el) |
PE (1) | PE20011033A1 (el) |
PL (1) | PL202999B1 (el) |
RU (1) | RU2242479C2 (el) |
SK (1) | SK287095B6 (el) |
TW (1) | TWI275593B (el) |
WO (1) | WO2001040255A2 (el) |
ZA (1) | ZA200203536B (el) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60004377T2 (de) * | 1999-04-06 | 2004-06-09 | Akzo Nobel N.V. | Oral wirksame 7-alpha-alkyl androgene |
MXPA04007049A (es) * | 2002-01-21 | 2004-10-14 | Akzo Nobel Nv | Proceso para la preparacion de 7a-metilesteroides. |
US20080293683A1 (en) * | 2007-05-24 | 2008-11-27 | University Of Kansas Medical Center | Hormone Replacement Therapy |
EP2383279A1 (en) | 2011-07-19 | 2011-11-02 | Pantarhei Bioscience B.V. | Process for the preparation of estetrol |
DK2764008T3 (en) * | 2011-10-07 | 2016-11-07 | Estetra Sprl | A process for the preparation of estetrol |
ES2877186T3 (es) | 2015-06-18 | 2021-11-16 | Estetra Sprl | Comprimido orodispersable que contiene estetrol |
GEP20217243B (en) | 2015-06-18 | 2021-04-26 | Sprl Estetra | Orodispersible dosage unit containing an estetrol component |
LT3310346T (lt) | 2015-06-18 | 2021-06-10 | Estetra Sprl | Burnoje disperguojama tabletė, turinti estetrolio |
TN2017000499A1 (en) | 2015-06-18 | 2019-04-12 | Mithra Pharmaceuticals S A | Orodispersible dosage unit containing an estetrol component |
KR20220144885A (ko) | 2016-08-05 | 2022-10-27 | 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 | 월경통 및 생리통의 관리방법 |
TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
JOP20200260A1 (ar) | 2018-04-19 | 2019-10-19 | Estetra Sprl | مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث |
CN111621141B (zh) * | 2020-06-12 | 2022-04-08 | 广西大学 | 一种缓释型二氧化氯-水性聚氨酯抗菌膜及其制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3086027A (en) | 1960-01-22 | 1963-04-16 | Lilly Co Eli | 19-nor-4, 9(10)-steroids and process |
IE60780B1 (en) * | 1987-01-23 | 1994-08-10 | Akzo Nv | New 11-aryl steroid derivatives |
DE19537626A1 (de) | 1995-10-10 | 1997-04-17 | Jenapharm Gmbh | Steroide mit einer 14, 15-Methylengruppe |
DE19827522A1 (de) * | 1998-06-22 | 1999-12-23 | Jenapharm Gmbh | 14,15-Cyclopropanosteroide der 19-Nor-Androstanreihe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate |
CA2359218A1 (en) | 1999-03-08 | 2000-09-14 | Akzo Nobel N.V. | 14.beta., 17-alpha-hydroxymethylandrostane derivatives as androgens |
-
2000
- 2000-11-29 ES ES00993259T patent/ES2258037T3/es not_active Expired - Lifetime
- 2000-11-29 CA CA002390226A patent/CA2390226A1/en not_active Abandoned
- 2000-11-29 HU HU0203611A patent/HUP0203611A3/hu unknown
- 2000-11-29 AT AT00993259T patent/ATE317396T1/de not_active IP Right Cessation
- 2000-11-29 JP JP2001541010A patent/JP2003515543A/ja active Pending
- 2000-11-29 PL PL355689A patent/PL202999B1/pl not_active IP Right Cessation
- 2000-11-29 CN CNB008164959A patent/CN1166680C/zh not_active Expired - Fee Related
- 2000-11-29 SK SK758-2002A patent/SK287095B6/sk not_active IP Right Cessation
- 2000-11-29 NZ NZ518753A patent/NZ518753A/en unknown
- 2000-11-29 RU RU2002117440/04A patent/RU2242479C2/ru not_active IP Right Cessation
- 2000-11-29 US US10/148,820 patent/US6706700B2/en not_active Expired - Fee Related
- 2000-11-29 EP EP00993259A patent/EP1237904B1/en not_active Expired - Lifetime
- 2000-11-29 AU AU28383/01A patent/AU778017B2/en not_active Ceased
- 2000-11-29 CZ CZ20021894A patent/CZ301376B6/cs not_active IP Right Cessation
- 2000-11-29 WO PCT/EP2000/012009 patent/WO2001040255A2/en active IP Right Grant
- 2000-11-29 DE DE60025958T patent/DE60025958T2/de not_active Expired - Lifetime
- 2000-11-29 DK DK00993259T patent/DK1237904T3/da active
- 2000-11-29 IL IL149424A patent/IL149424A/en not_active IP Right Cessation
- 2000-11-29 MX MXPA02004939A patent/MXPA02004939A/es active IP Right Grant
- 2000-11-30 AR ARP000106304A patent/AR026655A1/es active IP Right Grant
- 2000-12-01 PE PE2000001285A patent/PE20011033A1/es not_active Application Discontinuation
- 2000-12-01 CO CO00092012A patent/CO5251441A1/es not_active Application Discontinuation
- 2000-12-02 TW TW089125707A patent/TWI275593B/zh not_active IP Right Cessation
-
2002
- 2002-05-03 ZA ZA200203536A patent/ZA200203536B/en unknown
- 2002-05-30 NO NO20022564A patent/NO322422B1/no not_active IP Right Cessation
- 2002-12-18 HK HK02109169.4A patent/HK1047596B/zh not_active IP Right Cessation
-
2006
- 2006-04-10 CY CY20061100500T patent/CY1106086T1/el unknown
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