DK1237904T3 - 14,15-beta-methylensubstituerede androgener - Google Patents

14,15-beta-methylensubstituerede androgener

Info

Publication number
DK1237904T3
DK1237904T3 DK00993259T DK00993259T DK1237904T3 DK 1237904 T3 DK1237904 T3 DK 1237904T3 DK 00993259 T DK00993259 T DK 00993259T DK 00993259 T DK00993259 T DK 00993259T DK 1237904 T3 DK1237904 T3 DK 1237904T3
Authority
DK
Denmark
Prior art keywords
methylene
beta
androgens
substituted androgens
substituted
Prior art date
Application number
DK00993259T
Other languages
English (en)
Inventor
Der Louw Jaap Van
Bursi Roberta Buma
Gooyer Marcel Evert De
Dirk Leysen
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of DK1237904T3 publication Critical patent/DK1237904T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J53/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002Carbocyclic rings fused
    • C07J53/0043 membered carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26Androgens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
DK00993259T 1999-12-02 2000-11-29 14,15-beta-methylensubstituerede androgener DK1237904T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99204080 1999-12-02

Publications (1)

Publication Number Publication Date
DK1237904T3 true DK1237904T3 (da) 2006-06-06

Family

ID=8240955

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00993259T DK1237904T3 (da) 1999-12-02 2000-11-29 14,15-beta-methylensubstituerede androgener

Country Status (27)

Country Link
US (1) US6706700B2 (da)
EP (1) EP1237904B1 (da)
JP (1) JP2003515543A (da)
CN (1) CN1166680C (da)
AR (1) AR026655A1 (da)
AT (1) ATE317396T1 (da)
AU (1) AU778017B2 (da)
CA (1) CA2390226A1 (da)
CO (1) CO5251441A1 (da)
CY (1) CY1106086T1 (da)
CZ (1) CZ301376B6 (da)
DE (1) DE60025958T2 (da)
DK (1) DK1237904T3 (da)
ES (1) ES2258037T3 (da)
HK (1) HK1047596B (da)
HU (1) HUP0203611A3 (da)
IL (1) IL149424A (da)
MX (1) MXPA02004939A (da)
NO (1) NO322422B1 (da)
NZ (1) NZ518753A (da)
PE (1) PE20011033A1 (da)
PL (1) PL202999B1 (da)
RU (1) RU2242479C2 (da)
SK (1) SK287095B6 (da)
TW (1) TWI275593B (da)
WO (1) WO2001040255A2 (da)
ZA (1) ZA200203536B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2204613T3 (es) * 1999-04-06 2004-05-01 Akzo Nobel N.V. Androgenos 7-alfa alquilo oralmente activos.
TWI322813B (en) * 2002-01-21 2010-04-01 Organon Nv Process for the preparation of 7alpha-methylsteroids
US20080293683A1 (en) * 2007-05-24 2008-11-27 University Of Kansas Medical Center Hormone Replacement Therapy
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
JP6196625B2 (ja) * 2011-10-07 2017-09-13 エステトラ エス.ペ.エール.エル. エステトロールを製造するための方法
MY195019A (en) 2015-06-18 2023-01-03 Estetra Sprl Orodispersible dosage unit containing an estetrol component
ME03728B (me) 2015-06-18 2021-01-20 Estetra Sprl Orodisperzibilna dozna jedinica koja sadrži komponentu estetrola
RS61777B1 (sr) 2015-06-18 2021-06-30 Estetra Sprl Oralno-disperzibilna tableta koja sadrži estetrol
SI3310345T1 (sl) 2015-06-18 2021-05-31 Estetra Sprl Orodisperzibilna tableta, ki vsebuje estetrol
KR20220144885A (ko) 2016-08-05 2022-10-27 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 월경통 및 생리통의 관리방법
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
JOP20200260A1 (ar) 2018-04-19 2019-10-19 Estetra Sprl مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
CN111621141B (zh) * 2020-06-12 2022-04-08 广西大学 一种缓释型二氧化氯-水性聚氨酯抗菌膜及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3086027A (en) 1960-01-22 1963-04-16 Lilly Co Eli 19-nor-4, 9(10)-steroids and process
IE60780B1 (en) * 1987-01-23 1994-08-10 Akzo Nv New 11-aryl steroid derivatives
DE19537626A1 (de) * 1995-10-10 1997-04-17 Jenapharm Gmbh Steroide mit einer 14, 15-Methylengruppe
DE19827522A1 (de) 1998-06-22 1999-12-23 Jenapharm Gmbh 14,15-Cyclopropanosteroide der 19-Nor-Androstanreihe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
ATE228143T1 (de) 1999-03-08 2002-12-15 Akzo Nobel Nv 14.beta.,17-alpha-hydroxymethylandrostan derivate als androgene

Also Published As

Publication number Publication date
IL149424A (en) 2007-05-15
PL355689A1 (en) 2004-05-17
CY1106086T1 (el) 2011-06-08
ES2258037T3 (es) 2006-08-16
NZ518753A (en) 2004-05-28
NO20022564L (no) 2002-05-30
NO20022564D0 (no) 2002-05-30
ZA200203536B (en) 2003-08-04
AU2838301A (en) 2001-06-12
NO322422B1 (no) 2006-10-02
WO2001040255A3 (en) 2001-11-15
HUP0203611A2 (hu) 2003-03-28
AR026655A1 (es) 2003-02-19
CO5251441A1 (es) 2003-02-28
CZ301376B6 (cs) 2010-02-03
CA2390226A1 (en) 2001-06-07
TWI275593B (en) 2007-03-11
AU778017B2 (en) 2004-11-11
EP1237904A2 (en) 2002-09-11
HK1047596A1 (en) 2003-02-28
PL202999B1 (pl) 2009-08-31
WO2001040255A2 (en) 2001-06-07
DE60025958T2 (de) 2006-07-27
EP1237904B1 (en) 2006-02-08
CN1166680C (zh) 2004-09-15
IL149424A0 (en) 2002-11-10
US6706700B2 (en) 2004-03-16
CN1402735A (zh) 2003-03-12
MXPA02004939A (es) 2003-05-23
PE20011033A1 (es) 2001-10-11
JP2003515543A (ja) 2003-05-07
ATE317396T1 (de) 2006-02-15
SK287095B6 (sk) 2009-12-07
RU2242479C2 (ru) 2004-12-20
HK1047596B (zh) 2006-04-21
HUP0203611A3 (en) 2004-07-28
DE60025958D1 (de) 2006-04-20
SK7582002A3 (en) 2002-09-10
CZ20021894A3 (cs) 2002-08-14
US20030100543A1 (en) 2003-05-29

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