SK285428B6 - Použitie (-)-[[4-(1,4,5,6-tetrahydro-4-metyl-6-oxo-3- pyridazinyl)fenyl]hydrazono]propándinitrilu na výrobu lieku na liečbu vazospazmu koronárneho štepu - Google Patents

Použitie (-)-[[4-(1,4,5,6-tetrahydro-4-metyl-6-oxo-3- pyridazinyl)fenyl]hydrazono]propándinitrilu na výrobu lieku na liečbu vazospazmu koronárneho štepu Download PDF

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Publication number
SK285428B6
SK285428B6 SK1934-2001A SK19342001A SK285428B6 SK 285428 B6 SK285428 B6 SK 285428B6 SK 19342001 A SK19342001 A SK 19342001A SK 285428 B6 SK285428 B6 SK 285428B6
Authority
SK
Slovakia
Prior art keywords
levosimendan
vasospasm
coronary
treatment
pyridazinyl
Prior art date
Application number
SK1934-2001A
Other languages
English (en)
Slovak (sk)
Other versions
SK19342001A3 (sk
Inventor
Lasse Lehtonen
Julius Papp
Janos Szecsi
Original Assignee
Orion Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corporation filed Critical Orion Corporation
Publication of SK19342001A3 publication Critical patent/SK19342001A3/sk
Publication of SK285428B6 publication Critical patent/SK285428B6/sk

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Graft Or Block Polymers (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
SK1934-2001A 1999-06-29 2000-06-29 Použitie (-)-[[4-(1,4,5,6-tetrahydro-4-metyl-6-oxo-3- pyridazinyl)fenyl]hydrazono]propándinitrilu na výrobu lieku na liečbu vazospazmu koronárneho štepu SK285428B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9915179.7A GB9915179D0 (en) 1999-06-29 1999-06-29 A method for the treatment or prevention of coronary graft vasospasm
PCT/FI2000/000592 WO2001000211A1 (en) 1999-06-29 2000-06-29 A method for the treatment or prevention of coronary graft vasospasm

Publications (2)

Publication Number Publication Date
SK19342001A3 SK19342001A3 (sk) 2002-07-02
SK285428B6 true SK285428B6 (sk) 2007-01-04

Family

ID=10856266

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1934-2001A SK285428B6 (sk) 1999-06-29 2000-06-29 Použitie (-)-[[4-(1,4,5,6-tetrahydro-4-metyl-6-oxo-3- pyridazinyl)fenyl]hydrazono]propándinitrilu na výrobu lieku na liečbu vazospazmu koronárneho štepu

Country Status (19)

Country Link
US (1) US6593329B1 (pl)
EP (1) EP1191935B1 (pl)
JP (1) JP4628622B2 (pl)
KR (1) KR100762023B1 (pl)
AT (1) ATE293446T1 (pl)
AU (1) AU767361B2 (pl)
BR (1) BR0012072A (pl)
CA (1) CA2376930C (pl)
CZ (1) CZ294751B6 (pl)
DE (1) DE60019591T2 (pl)
EA (1) EA004142B1 (pl)
ES (1) ES2240110T3 (pl)
GB (1) GB9915179D0 (pl)
HU (1) HU228302B1 (pl)
NO (1) NO320315B1 (pl)
NZ (1) NZ516395A (pl)
PL (1) PL199973B1 (pl)
SK (1) SK285428B6 (pl)
WO (1) WO2001000211A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI104718B (fi) * 1998-06-18 2000-03-31 Orion Yhtymae Oyj [[4-(2-atsido-3-metyyli-5-oksotetrahydrofuran-2-yyli)fenyyli]hydratsono]propaanidinitriili käytettäväksi referenssiaineena levosimendaanierien analyysissä
FI20001542A (fi) 2000-06-29 2001-12-30 Orion Yhtymae Oyj Menetelmä septisen sokin hoitamiseksi
WO2008102563A1 (ja) 2007-02-23 2008-08-28 Next21 K.K. 血管攣縮の治療剤又は予防剤
JP2023507626A (ja) 2019-12-16 2023-02-24 テナックス・セラピューティクス，インコーポレイテッド 駆出率が保たれた心不全を伴う肺高血圧症（ＰＨ－ＨＦ－ｐＥＦ）を治療するためのレボシメンダン

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2251615B (en) * 1991-01-03 1995-02-08 Orion Yhtymae Oy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile
GB2266841A (en) * 1992-05-06 1993-11-17 Orion Yhtymae Oy Compounds for use as anti-ischemic medicaments
GB9614098D0 (en) * 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan

Also Published As

Publication number Publication date
EP1191935B1 (en) 2005-04-20
EA200200100A1 (ru) 2002-06-27
EA004142B1 (ru) 2004-02-26
NO20016316L (no) 2002-01-30
CZ20014685A3 (cs) 2002-08-14
AU767361B2 (en) 2003-11-06
SK19342001A3 (sk) 2002-07-02
HU228302B1 (en) 2013-03-28
DE60019591D1 (de) 2005-05-25
NO320315B1 (no) 2005-11-21
DE60019591T2 (de) 2006-03-02
KR20020020743A (ko) 2002-03-15
HUP0202085A3 (en) 2003-02-28
US6593329B1 (en) 2003-07-15
ATE293446T1 (de) 2005-05-15
CA2376930A1 (en) 2001-01-04
KR100762023B1 (ko) 2007-10-04
PL199973B1 (pl) 2008-11-28
EP1191935A1 (en) 2002-04-03
HUP0202085A2 (hu) 2002-12-28
JP2003503353A (ja) 2003-01-28
GB9915179D0 (en) 1999-09-01
CA2376930C (en) 2008-07-29
NZ516395A (en) 2005-02-25
BR0012072A (pt) 2002-04-02
WO2001000211A1 (en) 2001-01-04
CZ294751B6 (cs) 2005-03-16
JP4628622B2 (ja) 2011-02-09
ES2240110T3 (es) 2005-10-16
NO20016316D0 (no) 2001-12-21
PL352779A1 (pl) 2003-09-08
AU5687900A (en) 2001-01-31

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Legal Events

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MK4A Expiry of patent

Expiry date: 20200629