SK284646B6 - Bicyklická aromatická aminokyselina, spôsob jej prípravy, jej použitie a farmaceutický prostriedok, ktorý ju obsahuje - Google Patents
Bicyklická aromatická aminokyselina, spôsob jej prípravy, jej použitie a farmaceutický prostriedok, ktorý ju obsahuje Download PDFInfo
- Publication number
- SK284646B6 SK284646B6 SK1071-99A SK107199A SK284646B6 SK 284646 B6 SK284646 B6 SK 284646B6 SK 107199 A SK107199 A SK 107199A SK 284646 B6 SK284646 B6 SK 284646B6
- Authority
- SK
- Slovakia
- Prior art keywords
- propionic acid
- dihydro
- formula
- benzoxazin
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19705450A DE19705450A1 (de) | 1997-02-13 | 1997-02-13 | Bicyclische aromatische Aminosäuren |
| PCT/EP1998/000636 WO1998035949A1 (de) | 1997-02-13 | 1998-02-06 | Bicyclische aromatische aminosäuren |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK107199A3 SK107199A3 (en) | 2000-05-16 |
| SK284646B6 true SK284646B6 (sk) | 2005-08-04 |
Family
ID=7820093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1071-99A SK284646B6 (sk) | 1997-02-13 | 1998-02-06 | Bicyklická aromatická aminokyselina, spôsob jej prípravy, jej použitie a farmaceutický prostriedok, ktorý ju obsahuje |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP0964856B1 (no) |
| JP (1) | JP4327257B2 (no) |
| KR (1) | KR20000071030A (no) |
| CN (1) | CN1085205C (no) |
| AR (1) | AR010894A1 (no) |
| AT (1) | ATE225776T1 (no) |
| AU (1) | AU735313B2 (no) |
| BR (1) | BR9807345A (no) |
| CA (1) | CA2280727C (no) |
| CY (1) | CY2341B1 (no) |
| CZ (1) | CZ297366B6 (no) |
| DE (2) | DE19705450A1 (no) |
| DK (1) | DK0964856T3 (no) |
| ES (1) | ES2183332T3 (no) |
| HU (1) | HUP0001138A3 (no) |
| ID (1) | ID22533A (no) |
| NO (1) | NO313289B1 (no) |
| PL (1) | PL335101A1 (no) |
| PT (1) | PT964856E (no) |
| RU (1) | RU2187506C2 (no) |
| SI (1) | SI0964856T1 (no) |
| SK (1) | SK284646B6 (no) |
| TR (1) | TR199901962T2 (no) |
| WO (1) | WO1998035949A1 (no) |
| ZA (1) | ZA981178B (no) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040063790A1 (en) * | 1996-05-31 | 2004-04-01 | The Scripps Research Institute | Methods for inhibition of angiogenesis |
| CN1140511C (zh) | 1998-04-09 | 2004-03-03 | 明治制果株式会社 | 作为整合素αvβ3拮抗剂的氨基哌啶衍生物 |
| EP1171435A2 (de) | 1999-04-13 | 2002-01-16 | Basf Aktiengesellschaft | Pyrimidin-2-on derivate als integrinrezeptorliganden |
| US6750219B1 (en) | 1999-08-05 | 2004-06-15 | Meiji Seika Kaisha, Ltd. | Ω-amino-α-hydroxycarboxylic acid derivatives having integrin ανβ3 antagonistic activity |
| US20030199571A1 (en) * | 1999-12-24 | 2003-10-23 | Gordon Bruton | (Hetero) Bicyclymethanesulfonylamino-substituted hydroxamic acid derivatives |
| AU2880701A (en) * | 2000-01-25 | 2001-08-07 | Kaneka Corporation | Process for preparation of optically active n-substituted azetidine-2-carboxylicacids |
| SK5902003A3 (en) | 2000-11-01 | 2003-08-05 | Merck Patent Gmbh | Methods and compositions for the treatment of diseases of the eye |
| MXPA03010893A (es) | 2001-05-30 | 2004-10-28 | Univ Leland Stanford Junior | Sistema de suministro para acidos nucleicos. |
| HUP0401605A3 (en) * | 2001-08-01 | 2012-09-28 | Merck Patent Gmbh | Integrin inhibitors for the treatment of eye diseases |
| PL371281A1 (en) * | 2002-02-14 | 2005-06-13 | Merck Patent Gmbh | Methods and compositions for the treatment of eye diseases |
| DE10305784A1 (de) * | 2003-02-12 | 2004-08-26 | Merck Patent Gmbh | Verfahren zur Herstellug bicyclischer aromatischer Aminosäuren sowie deren Zwischenprodukte |
| DE10337863A1 (de) | 2003-08-18 | 2005-03-17 | Merck Patent Gmbh | Verwendung von Chromen-4-on-Derivaten |
| ES2439390T3 (es) * | 2004-06-04 | 2014-01-22 | The Scripps Research Institute | Composiciones y procedimiento para el tratamiento de enfermedades neovasculares |
| UA87854C2 (en) | 2004-06-07 | 2009-08-25 | Мерк Энд Ко., Инк. | N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators |
| LT2380881T (lt) * | 2008-12-26 | 2017-04-10 | Sumitomo Dainippon Pharma Co., Ltd. | Naujas biciklinis heterociklinis junginys |
| WO2011024987A1 (ja) * | 2009-08-31 | 2011-03-03 | 塩野義製薬株式会社 | 芳香族縮合へテロ環誘導体およびそれらを含有する医薬組成物 |
| EA201400976A1 (ru) | 2012-03-06 | 2015-02-27 | Бёрингер Ингельхайм Интернациональ Гмбх | Бензодиоксаны в комбинации с другими активными средствами для ингибирования продуцирования лейкотриена |
| JP6256467B2 (ja) | 2012-07-17 | 2018-01-10 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ロイコトリエン生成を阻害するピラゾール誘導体 |
| WO2015009609A1 (en) | 2013-07-15 | 2015-01-22 | Boehringer Ingelheim International Gmbh | Inhibitors of leukotriene production |
| JP2016523982A (ja) | 2013-07-15 | 2016-08-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ロイコトリエン生成の阻害剤 |
| MX2016015467A (es) | 2014-05-30 | 2017-03-23 | Pfizer | Derivados de carbonitrilo como moduladores selectivos del receptor de androgenos. |
| WO2023275715A1 (en) | 2021-06-30 | 2023-01-05 | Pfizer Inc. | Metabolites of selective androgen receptor modulators |
| US11957671B2 (en) | 2021-11-01 | 2024-04-16 | Alkahest, Inc. | Benzodioxane modulators of leukotriene A4 hydrolase (LTA4H) for prevention and treatment of aging-associated diseases |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0673247A4 (en) * | 1992-12-01 | 1996-05-01 | Merck & Co Inc | FIBRINOGEN RECEPTOR ANTAGONISTS. |
| DE69528829T2 (de) * | 1994-05-27 | 2003-08-07 | Merck & Co., Inc. | Präparate zur hemmung der durch osteoklasten vermittelten knochenresorption |
| DE19548709A1 (de) * | 1995-12-23 | 1997-07-03 | Merck Patent Gmbh | Tyrosinderivate |
| WO1998000395A1 (de) * | 1996-06-28 | 1998-01-08 | Merck Patent Gmbh | Phenylalanin-derivate als integrin-inhibitoren |
| DE19654483A1 (de) * | 1996-06-28 | 1998-01-02 | Merck Patent Gmbh | Phenylalanin-Derivate |
-
1997
- 1997-02-13 DE DE19705450A patent/DE19705450A1/de not_active Withdrawn
-
1998
- 1998-02-06 KR KR1019997007297A patent/KR20000071030A/ko not_active Application Discontinuation
- 1998-02-06 SI SI9830304T patent/SI0964856T1/xx unknown
- 1998-02-06 JP JP53530398A patent/JP4327257B2/ja not_active Expired - Fee Related
- 1998-02-06 PL PL98335101A patent/PL335101A1/xx unknown
- 1998-02-06 TR TR1999/01962T patent/TR199901962T2/xx unknown
- 1998-02-06 ID IDW990812A patent/ID22533A/id unknown
- 1998-02-06 AT AT98908063T patent/ATE225776T1/de not_active IP Right Cessation
- 1998-02-06 BR BR9807345A patent/BR9807345A/pt not_active Application Discontinuation
- 1998-02-06 CA CA002280727A patent/CA2280727C/en not_active Expired - Fee Related
- 1998-02-06 AU AU66206/98A patent/AU735313B2/en not_active Ceased
- 1998-02-06 ES ES98908063T patent/ES2183332T3/es not_active Expired - Lifetime
- 1998-02-06 RU RU99119223/04A patent/RU2187506C2/ru not_active IP Right Cessation
- 1998-02-06 CN CN98803959A patent/CN1085205C/zh not_active Expired - Fee Related
- 1998-02-06 SK SK1071-99A patent/SK284646B6/sk unknown
- 1998-02-06 PT PT98908063T patent/PT964856E/pt unknown
- 1998-02-06 HU HU0001138A patent/HUP0001138A3/hu unknown
- 1998-02-06 DK DK98908063T patent/DK0964856T3/da active
- 1998-02-06 EP EP98908063A patent/EP0964856B1/de not_active Expired - Lifetime
- 1998-02-06 DE DE59805895T patent/DE59805895D1/de not_active Expired - Lifetime
- 1998-02-06 CZ CZ0287599A patent/CZ297366B6/cs not_active IP Right Cessation
- 1998-02-06 WO PCT/EP1998/000636 patent/WO1998035949A1/de active IP Right Grant
- 1998-02-12 ZA ZA981178A patent/ZA981178B/xx unknown
- 1998-02-13 AR ARP980100654A patent/AR010894A1/es not_active Application Discontinuation
-
1999
- 1999-08-12 NO NO19993901A patent/NO313289B1/no not_active IP Right Cessation
-
2003
- 2003-03-17 CY CY0300028A patent/CY2341B1/xx unknown
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