ZA981178B - Bicyclic aromatic amino acids - Google Patents
Bicyclic aromatic amino acidsInfo
- Publication number
- ZA981178B ZA981178B ZA981178A ZA981178A ZA981178B ZA 981178 B ZA981178 B ZA 981178B ZA 981178 A ZA981178 A ZA 981178A ZA 981178 A ZA981178 A ZA 981178A ZA 981178 B ZA981178 B ZA 981178B
- Authority
- ZA
- South Africa
- Prior art keywords
- amino acids
- aromatic amino
- bicyclic aromatic
- bicyclic
- acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19705450A DE19705450A1 (en) | 1997-02-13 | 1997-02-13 | Bicyclic aromatic amino acids |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA981178B true ZA981178B (en) | 1999-05-21 |
Family
ID=7820093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA981178A ZA981178B (en) | 1997-02-13 | 1998-02-12 | Bicyclic aromatic amino acids |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP0964856B1 (en) |
JP (1) | JP4327257B2 (en) |
KR (1) | KR20000071030A (en) |
CN (1) | CN1085205C (en) |
AR (1) | AR010894A1 (en) |
AT (1) | ATE225776T1 (en) |
AU (1) | AU735313B2 (en) |
BR (1) | BR9807345A (en) |
CA (1) | CA2280727C (en) |
CY (1) | CY2341B1 (en) |
CZ (1) | CZ297366B6 (en) |
DE (2) | DE19705450A1 (en) |
DK (1) | DK0964856T3 (en) |
ES (1) | ES2183332T3 (en) |
HU (1) | HUP0001138A3 (en) |
ID (1) | ID22533A (en) |
NO (1) | NO313289B1 (en) |
PL (1) | PL335101A1 (en) |
PT (1) | PT964856E (en) |
RU (1) | RU2187506C2 (en) |
SI (1) | SI0964856T1 (en) |
SK (1) | SK284646B6 (en) |
TR (1) | TR199901962T2 (en) |
WO (1) | WO1998035949A1 (en) |
ZA (1) | ZA981178B (en) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040063790A1 (en) * | 1996-05-31 | 2004-04-01 | The Scripps Research Institute | Methods for inhibition of angiogenesis |
AU759449C (en) | 1998-04-09 | 2003-10-30 | Meiji Seika Pharma Co.,Ltd. | Aminopiperidine derivatives as integrin alpha v beta 3 antagonists |
TR200102944T2 (en) | 1999-04-13 | 2002-08-21 | Basf Aktiengesellschaft | Integrin receptor ligands |
WO2001010844A1 (en) | 1999-08-05 | 2001-02-15 | Meiji Seika Kaisha, Ltd. | φ-AMINO-α-HYDROXYCARBOXYLIC ACID DERIVATIVES HAVING INTEGRIN αvβ3 ANTAGONISM |
AU2207001A (en) * | 1999-12-24 | 2001-07-09 | Smithkline Beecham Plc | Novel compounds and process |
DE60101351T2 (en) * | 2000-01-25 | 2004-10-07 | Kaneka Corp | METHOD FOR PRODUCING OPTICALLY ACTIVE, N-SUBSTITUTED AZETIDINE-2-CARBONIC ACIDS |
ATE415163T1 (en) * | 2000-11-01 | 2008-12-15 | Merck Patent Gmbh | METHODS AND COMPOSITIONS FOR TREATING EYE DISEASES |
JP4323949B2 (en) | 2001-05-30 | 2009-09-02 | ザ・スクリプス・リサーチ・インステイチユート | Nucleic acid delivery system |
HUP0401605A3 (en) * | 2001-08-01 | 2012-09-28 | Merck Patent Gmbh | Integrin inhibitors for the treatment of eye diseases |
BR0307627A (en) * | 2002-02-14 | 2005-01-11 | Merck Patent Gmbh | Methods and compositions for treating eye diseases |
DE10305784A1 (en) * | 2003-02-12 | 2004-08-26 | Merck Patent Gmbh | 3-Oxo-3,4-dihydro-2H-benz-(1,4)-oxazin-6-yl)-propionic acid derivative preparation, for use as integrin inhibitors with e.g. antitumor action, by multi-stage process giving diastereomerically pure product |
DE10337863A1 (en) | 2003-08-18 | 2005-03-17 | Merck Patent Gmbh | Use of chromene-4-one derivatives |
ATE551060T1 (en) * | 2004-06-04 | 2012-04-15 | Scripps Research Inst | COMPOSITIONS AND METHODS FOR TREATING NEOVASCULAR DISEASES |
UA87854C2 (en) | 2004-06-07 | 2009-08-25 | Мерк Энд Ко., Инк. | N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators |
RU2518073C2 (en) * | 2008-12-26 | 2014-06-10 | ДАЙНИППОН СУМИТОМО ФАРМА Ко., ЛТД. | Novel bicyclic heterocyclic compound |
WO2011024987A1 (en) * | 2009-08-31 | 2011-03-03 | 塩野義製薬株式会社 | Aromatic fused heterocyclic derivative and pharmaceutical composition containing same |
WO2013131901A1 (en) | 2012-03-06 | 2013-09-12 | Boehringer Ingelheim International Gmbh | Benzodioxanes in combination with other actives for inhibiting leukotriene production |
WO2014014874A1 (en) | 2012-07-17 | 2014-01-23 | Boehringer Ingelheim International Gmbh | Pyrazole derivatives which inhibit leukotriene production |
WO2015009611A1 (en) | 2013-07-15 | 2015-01-22 | Boehringer Ingelheim International Gmbh | Inhibitors of leukotriene production |
US9303018B2 (en) | 2013-07-15 | 2016-04-05 | Boehringer Ingelheim International Gmbh | Inhibitors of leukotriene production |
EP3148587B1 (en) | 2014-05-30 | 2021-02-24 | Pfizer Inc | Carbonitrile derivatives as selective androgen receptor modulators |
WO2023275715A1 (en) | 2021-06-30 | 2023-01-05 | Pfizer Inc. | Metabolites of selective androgen receptor modulators |
AU2022376563A1 (en) | 2021-11-01 | 2023-12-07 | Alkahest, Inc. | Benzodioxane modulators of leukotriene a4 hydrolase (lta4h) for prevention and treatment of aging-associated diseases |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08504194A (en) * | 1992-12-01 | 1996-05-07 | メルク エンド カンパニー インコーポレーテッド | Fibrinogen receptor antagonist |
ATE227567T1 (en) * | 1994-05-27 | 2002-11-15 | Merck & Co Inc | PREPARATIONS FOR INHIBITING BONE RESORPTION MEDIATED BY OSTEOCLASTS |
DE19548709A1 (en) * | 1995-12-23 | 1997-07-03 | Merck Patent Gmbh | Tyrosine derivatives |
DE19654483A1 (en) * | 1996-06-28 | 1998-01-02 | Merck Patent Gmbh | Phenylalanine derivatives |
JP2000516575A (en) * | 1996-06-28 | 2000-12-12 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | Phenylalanine derivatives as integrin inhibitors |
-
1997
- 1997-02-13 DE DE19705450A patent/DE19705450A1/en not_active Withdrawn
-
1998
- 1998-02-06 WO PCT/EP1998/000636 patent/WO1998035949A1/en active IP Right Grant
- 1998-02-06 CN CN98803959A patent/CN1085205C/en not_active Expired - Fee Related
- 1998-02-06 ID IDW990812A patent/ID22533A/en unknown
- 1998-02-06 CA CA002280727A patent/CA2280727C/en not_active Expired - Fee Related
- 1998-02-06 SK SK1071-99A patent/SK284646B6/en unknown
- 1998-02-06 BR BR9807345A patent/BR9807345A/en not_active Application Discontinuation
- 1998-02-06 PL PL98335101A patent/PL335101A1/en unknown
- 1998-02-06 CZ CZ0287599A patent/CZ297366B6/en not_active IP Right Cessation
- 1998-02-06 AU AU66206/98A patent/AU735313B2/en not_active Ceased
- 1998-02-06 JP JP53530398A patent/JP4327257B2/en not_active Expired - Fee Related
- 1998-02-06 PT PT98908063T patent/PT964856E/en unknown
- 1998-02-06 TR TR1999/01962T patent/TR199901962T2/en unknown
- 1998-02-06 HU HU0001138A patent/HUP0001138A3/en unknown
- 1998-02-06 DK DK98908063T patent/DK0964856T3/en active
- 1998-02-06 ES ES98908063T patent/ES2183332T3/en not_active Expired - Lifetime
- 1998-02-06 EP EP98908063A patent/EP0964856B1/en not_active Expired - Lifetime
- 1998-02-06 KR KR1019997007297A patent/KR20000071030A/en not_active Application Discontinuation
- 1998-02-06 RU RU99119223/04A patent/RU2187506C2/en not_active IP Right Cessation
- 1998-02-06 SI SI9830304T patent/SI0964856T1/en unknown
- 1998-02-06 AT AT98908063T patent/ATE225776T1/en not_active IP Right Cessation
- 1998-02-06 DE DE59805895T patent/DE59805895D1/en not_active Expired - Lifetime
- 1998-02-12 ZA ZA981178A patent/ZA981178B/en unknown
- 1998-02-13 AR ARP980100654A patent/AR010894A1/en not_active Application Discontinuation
-
1999
- 1999-08-12 NO NO19993901A patent/NO313289B1/en not_active IP Right Cessation
-
2003
- 2003-03-17 CY CY0300028A patent/CY2341B1/en unknown
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