DK0964856T3 - Bicyclic aromatic amino acids - Google Patents
Bicyclic aromatic amino acidsInfo
- Publication number
- DK0964856T3 DK0964856T3 DK98908063T DK98908063T DK0964856T3 DK 0964856 T3 DK0964856 T3 DK 0964856T3 DK 98908063 T DK98908063 T DK 98908063T DK 98908063 T DK98908063 T DK 98908063T DK 0964856 T3 DK0964856 T3 DK 0964856T3
- Authority
- DK
- Denmark
- Prior art keywords
- amino acids
- aromatic amino
- bicyclic aromatic
- bicyclic
- acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19705450A DE19705450A1 (en) | 1997-02-13 | 1997-02-13 | Bicyclic aromatic amino acids |
| PCT/EP1998/000636 WO1998035949A1 (en) | 1997-02-13 | 1998-02-06 | Bicyclic amino acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0964856T3 true DK0964856T3 (en) | 2003-02-10 |
Family
ID=7820093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98908063T DK0964856T3 (en) | 1997-02-13 | 1998-02-06 | Bicyclic aromatic amino acids |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP0964856B1 (en) |
| JP (1) | JP4327257B2 (en) |
| KR (1) | KR20000071030A (en) |
| CN (1) | CN1085205C (en) |
| AR (1) | AR010894A1 (en) |
| AT (1) | ATE225776T1 (en) |
| AU (1) | AU735313B2 (en) |
| BR (1) | BR9807345A (en) |
| CA (1) | CA2280727C (en) |
| CY (1) | CY2341B1 (en) |
| CZ (1) | CZ297366B6 (en) |
| DE (2) | DE19705450A1 (en) |
| DK (1) | DK0964856T3 (en) |
| ES (1) | ES2183332T3 (en) |
| HU (1) | HUP0001138A3 (en) |
| ID (1) | ID22533A (en) |
| NO (1) | NO313289B1 (en) |
| PL (1) | PL335101A1 (en) |
| PT (1) | PT964856E (en) |
| RU (1) | RU2187506C2 (en) |
| SI (1) | SI0964856T1 (en) |
| SK (1) | SK284646B6 (en) |
| TR (1) | TR199901962T2 (en) |
| WO (1) | WO1998035949A1 (en) |
| ZA (1) | ZA981178B (en) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040063790A1 (en) * | 1996-05-31 | 2004-04-01 | The Scripps Research Institute | Methods for inhibition of angiogenesis |
| CA2327673C (en) | 1998-04-09 | 2009-08-25 | Meiji Seika Kaisha, Ltd. | Aminopiperidine derivatives as integrin .alpha.v.beta.3 antagonists |
| PL351279A1 (en) | 1999-04-13 | 2003-04-07 | Abbott Gmbh & Co Kg | Integrin receptor ligands |
| EP1209152A4 (en) | 1999-08-05 | 2003-03-12 | Meiji Seika Kaisha | Omega-amino-alpha-hydroxycarboxylic acid derivatives having integrin alpha v beta 3 antagonism |
| JP2003519119A (en) * | 1999-12-24 | 2003-06-17 | スミスクライン ビーチャム パブリック リミテッド カンパニー | (Hetero) bicyclylmethanesulfonylamino-substituted hydroxamic acid derivatives |
| US6617461B2 (en) * | 2000-01-25 | 2003-09-09 | Kaneka Corporation | Process for preparation of optically active N-substituted azetidine-2-carboxylic acids |
| WO2002041910A2 (en) | 2000-11-01 | 2002-05-30 | Merck Patent Gmbh | Methods and compositions for the treatment of diseases of the eye |
| WO2002097116A2 (en) | 2001-05-30 | 2002-12-05 | The Scripps Research Institute | Delivery system for nucleic acids |
| DK1411926T3 (en) * | 2001-08-01 | 2005-08-29 | Merck Patent Gmbh | Integrin inhibitors for the treatment of eye diseases |
| US20050085415A1 (en) * | 2002-02-14 | 2005-04-21 | Matthias Wiesner | Methods and compositions for the treatment of eye diseases |
| DE10305784A1 (en) * | 2003-02-12 | 2004-08-26 | Merck Patent Gmbh | 3-Oxo-3,4-dihydro-2H-benz-(1,4)-oxazin-6-yl)-propionic acid derivative preparation, for use as integrin inhibitors with e.g. antitumor action, by multi-stage process giving diastereomerically pure product |
| DE10337863A1 (en) | 2003-08-18 | 2005-03-17 | Merck Patent Gmbh | Use of chromene-4-one derivatives |
| AU2005249586B2 (en) * | 2004-06-04 | 2010-12-23 | The Scripps Research Institute | Compositions and methods for treatment of neovascular diseases |
| UA87854C2 (en) | 2004-06-07 | 2009-08-25 | Мерк Энд Ко., Инк. | N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators |
| LT2380881T (en) * | 2008-12-26 | 2017-04-10 | Sumitomo Dainippon Pharma Co., Ltd. | Novel bicyclic heterocyclic compound |
| WO2011024987A1 (en) * | 2009-08-31 | 2011-03-03 | 塩野義製薬株式会社 | Aromatic fused heterocyclic derivative and pharmaceutical composition containing same |
| CA2866471A1 (en) | 2012-03-06 | 2013-09-12 | Boehringer Ingelheim International Gmbh | Benzodioxanes in combination with other actives for inhibiting leukotriene production |
| JP6256467B2 (en) | 2012-07-17 | 2018-01-10 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Pyrazole derivatives that inhibit leukotriene formation |
| EP3022193B1 (en) | 2013-07-15 | 2017-04-26 | Boehringer Ingelheim International GmbH | Inhibitors of leukotriene production |
| WO2015009611A1 (en) | 2013-07-15 | 2015-01-22 | Boehringer Ingelheim International Gmbh | Inhibitors of leukotriene production |
| KR20160147007A (en) | 2014-05-30 | 2016-12-21 | 화이자 인코포레이티드 | Carbonitrile derivatives as selective androgen receptor modulators |
| WO2023275715A1 (en) | 2021-06-30 | 2023-01-05 | Pfizer Inc. | Metabolites of selective androgen receptor modulators |
| US11957671B2 (en) | 2021-11-01 | 2024-04-16 | Alkahest, Inc. | Benzodioxane modulators of leukotriene A4 hydrolase (LTA4H) for prevention and treatment of aging-associated diseases |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2150550A1 (en) * | 1992-12-01 | 1994-06-09 | Melissa S. Egbertson | Fibrinogen receptor antagonists |
| WO1995032710A1 (en) * | 1994-05-27 | 1995-12-07 | Merck & Co., Inc. | Compounds for inhibiting osteoclast-mediated bone resorption |
| DE19548709A1 (en) * | 1995-12-23 | 1997-07-03 | Merck Patent Gmbh | Tyrosine derivatives |
| DE19654483A1 (en) * | 1996-06-28 | 1998-01-02 | Merck Patent Gmbh | Phenylalanine derivatives |
| AU3343097A (en) * | 1996-06-28 | 1998-01-21 | Merck Patent Gmbh | Phenylalamine derivatives as integrin inhibitors |
-
1997
- 1997-02-13 DE DE19705450A patent/DE19705450A1/en not_active Withdrawn
-
1998
- 1998-02-06 AT AT98908063T patent/ATE225776T1/en not_active IP Right Cessation
- 1998-02-06 CN CN98803959A patent/CN1085205C/en not_active Expired - Fee Related
- 1998-02-06 HU HU0001138A patent/HUP0001138A3/en unknown
- 1998-02-06 BR BR9807345A patent/BR9807345A/en not_active Application Discontinuation
- 1998-02-06 JP JP53530398A patent/JP4327257B2/en not_active Expired - Fee Related
- 1998-02-06 SI SI9830304T patent/SI0964856T1/en unknown
- 1998-02-06 AU AU66206/98A patent/AU735313B2/en not_active Ceased
- 1998-02-06 CA CA002280727A patent/CA2280727C/en not_active Expired - Fee Related
- 1998-02-06 KR KR1019997007297A patent/KR20000071030A/en not_active Application Discontinuation
- 1998-02-06 DK DK98908063T patent/DK0964856T3/en active
- 1998-02-06 RU RU99119223/04A patent/RU2187506C2/en not_active IP Right Cessation
- 1998-02-06 ID IDW990812A patent/ID22533A/en unknown
- 1998-02-06 WO PCT/EP1998/000636 patent/WO1998035949A1/en active IP Right Grant
- 1998-02-06 SK SK1071-99A patent/SK284646B6/en unknown
- 1998-02-06 PL PL98335101A patent/PL335101A1/en unknown
- 1998-02-06 ES ES98908063T patent/ES2183332T3/en not_active Expired - Lifetime
- 1998-02-06 DE DE59805895T patent/DE59805895D1/en not_active Expired - Lifetime
- 1998-02-06 TR TR1999/01962T patent/TR199901962T2/en unknown
- 1998-02-06 CZ CZ0287599A patent/CZ297366B6/en not_active IP Right Cessation
- 1998-02-06 EP EP98908063A patent/EP0964856B1/en not_active Expired - Lifetime
- 1998-02-06 PT PT98908063T patent/PT964856E/en unknown
- 1998-02-12 ZA ZA981178A patent/ZA981178B/en unknown
- 1998-02-13 AR ARP980100654A patent/AR010894A1/en not_active Application Discontinuation
-
1999
- 1999-08-12 NO NO19993901A patent/NO313289B1/en not_active IP Right Cessation
-
2003
- 2003-03-17 CY CY0300028A patent/CY2341B1/en unknown
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