SK283685B6 - Kryštálová modifikácia 1-(2,6-difluórbenzyl)-1H-1,2,3-triazol-4- karboxamidu, farmaceutické prípravky, ktoré ju obsahujú, a jej použitie - Google Patents

Kryštálová modifikácia 1-(2,6-difluórbenzyl)-1H-1,2,3-triazol-4- karboxamidu, farmaceutické prípravky, ktoré ju obsahujú, a jej použitie Download PDF

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Publication number
SK283685B6
SK283685B6 SK1093-98A SK109398A SK283685B6 SK 283685 B6 SK283685 B6 SK 283685B6 SK 109398 A SK109398 A SK 109398A SK 283685 B6 SK283685 B6 SK 283685B6
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SK
Slovakia
Prior art keywords
weak
modification
difluorobenzyl
triazole
carboxamide
Prior art date
Application number
SK1093-98A
Other languages
English (en)
Slovak (sk)
Other versions
SK109398A3 (en
Inventor
Robert Portmann
Urs Christoph Hofmeier
Andreas Burkhard
Walter Scherrer
Martin Szelagiewicz
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4209650&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK283685(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SK109398A3 publication Critical patent/SK109398A3/sk
Publication of SK283685B6 publication Critical patent/SK283685B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
SK1093-98A 1997-06-10 1998-06-08 Kryštálová modifikácia 1-(2,6-difluórbenzyl)-1H-1,2,3-triazol-4- karboxamidu, farmaceutické prípravky, ktoré ju obsahujú, a jej použitie SK283685B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH140497 1997-06-10
PCT/EP1998/003427 WO1998056772A1 (en) 1997-06-10 1998-06-08 Crystal modification of 1-(2,6-difluorobenzyl)-1h-1,2,3--triazole-4-carboxamide and its use as antiepileptic

Publications (2)

Publication Number Publication Date
SK109398A3 SK109398A3 (en) 1998-12-02
SK283685B6 true SK283685B6 (sk) 2003-12-02

Family

ID=4209650

Family Applications (2)

Application Number Title Priority Date Filing Date
SK1094-98A SK283734B6 (sk) 1997-06-10 1998-06-08 Kryštálové modifikácie 1-(2,6-difluórbenzyl)-1H-1,2,3-triazol-4- karboxamidu, farmaceutické prípravky, ktoré ich obsahujú, a ich použitie
SK1093-98A SK283685B6 (sk) 1997-06-10 1998-06-08 Kryštálová modifikácia 1-(2,6-difluórbenzyl)-1H-1,2,3-triazol-4- karboxamidu, farmaceutické prípravky, ktoré ju obsahujú, a jej použitie

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SK1094-98A SK283734B6 (sk) 1997-06-10 1998-06-08 Kryštálové modifikácie 1-(2,6-difluórbenzyl)-1H-1,2,3-triazol-4- karboxamidu, farmaceutické prípravky, ktoré ich obsahujú, a ich použitie

Country Status (37)

Country Link
US (6) US6740669B1 (nl)
EP (2) EP0994863B1 (nl)
JP (2) JP3672575B2 (nl)
KR (2) KR100409168B1 (nl)
CN (3) CN1159300C (nl)
AR (4) AR012946A1 (nl)
AT (2) ATE237599T1 (nl)
AU (2) AU725517B2 (nl)
BR (2) BR9804947A (nl)
CA (3) CA2614926C (nl)
CO (2) CO4940448A1 (nl)
CY (1) CY2007014I1 (nl)
CZ (2) CZ292481B6 (nl)
DE (3) DE69811500T2 (nl)
DK (2) DK0994864T3 (nl)
ES (2) ES2197485T3 (nl)
FR (1) FR07C0037I2 (nl)
HK (3) HK1028242A1 (nl)
HU (2) HU226107B1 (nl)
ID (2) ID21014A (nl)
IL (2) IL125732A (nl)
LU (1) LU91345I2 (nl)
MY (2) MY125854A (nl)
NL (1) NL300284I2 (nl)
NO (2) NO329315B1 (nl)
NZ (2) NZ331370A (nl)
PE (2) PE80999A1 (nl)
PL (2) PL192114B1 (nl)
PT (1) PT994864E (nl)
RU (2) RU2194041C2 (nl)
SI (2) SI0994864T1 (nl)
SK (2) SK283734B6 (nl)
TR (2) TR199801631T1 (nl)
TW (2) TW526195B (nl)
UY (1) UY25844A1 (nl)
WO (2) WO1998056773A1 (nl)
ZA (2) ZA984967B (nl)

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TW526195B (en) 1997-06-10 2003-04-01 Novartis Ag Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use
ATE390425T1 (de) * 2002-05-31 2008-04-15 Schering Corp Xanthin-phosphodiesterase-v-hemmer polymorphe
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
US7875284B2 (en) * 2006-03-10 2011-01-25 Cook Incorporated Methods of manufacturing and modifying taxane coatings for implantable medical devices
US20090069390A1 (en) * 2007-09-12 2009-03-12 Protia, Llc Deuterium-enriched rufinamide
CA2736703A1 (en) * 2008-10-13 2010-04-22 Cipla Limited Process for the preparation of rufinamide
CN101768124B (zh) * 2008-12-30 2012-01-04 北京本草天源药物研究院 一种药物晶体及其制备方法和用途
IT1395736B1 (it) 2009-08-04 2012-10-19 Dipharma Francis Srl Forme cristalline di rufinamide
RU2594155C2 (ru) * 2009-09-04 2016-08-10 Тэктикал Терапеутикс, Инк Новые композиции и способы получения 5-амино- или замещенных амино-1,2,3-триазолов и триазол-оротатных композиций
EP2465853A1 (en) * 2010-12-14 2012-06-20 Laboratorios Lesvi, S.L. Polymorph of rufinamide and process for obtaining it
EP2727914A1 (en) * 2010-04-30 2014-05-07 Laboratorios Lesvi, S.L. Polymorph of 1-(2,6-difluorobenzyl)-1h-1,2,3-triazole-carboxamide
ITMI20110718A1 (it) 2011-04-29 2012-10-30 Dipharma Francis Srl Procedimento per la purificazione di rufinamide
WO2014013511A2 (en) * 2012-07-20 2014-01-23 Hetero Research Foundation Rufinamide solid dispersion
WO2021099481A1 (en) 2019-11-20 2021-05-27 Medichem, S.A. Solid composition containing rufinamide

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US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
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US4789680A (en) * 1982-12-23 1988-12-06 Ciba-Geigy Corporation Aralkyltriazole compounds
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IL96507A0 (en) 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them
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JP2753911B2 (ja) 1991-12-06 1998-05-20 キッセイ薬品工業株式会社 Ｎ−ｔｅｒｔ−ブチル−１−メチル−３，３−ジフェニルプロピルアミン塩酸塩の結晶多形およびその製造方法
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TW526195B (en) * 1997-06-10 2003-04-01 Novartis Ag Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use

Also Published As

Publication number Publication date
PE80999A1 (es) 1999-09-06
LU91345I2 (fr) 2007-09-04
DK0994864T3 (da) 2003-07-21
SI0994864T1 (en) 2003-10-31
CA2614926A1 (en) 1998-12-17
DE69813560T2 (de) 2004-02-05
UY25844A1 (es) 2001-08-27
JP3672574B2 (ja) 2005-07-20
TR199801630T1 (xx) 1999-06-21
CN1159300C (zh) 2004-07-28
ATE237599T1 (de) 2003-05-15
LU91345I9 (nl) 2018-12-31
HK1028031A1 (en) 2001-02-02
CN1298708C (zh) 2007-02-07
CA2256015C (en) 2008-06-03
AU725517B2 (en) 2000-10-12
DE69811500T2 (de) 2004-04-01
US6455556B2 (en) 2002-09-24
US20060116520A1 (en) 2006-06-01
CZ253398A3 (cs) 1999-04-14
ES2197485T3 (es) 2004-01-01
EP0994864A1 (en) 2000-04-26
CN1132820C (zh) 2003-12-31
PL330798A1 (en) 1999-06-07
RU2198167C2 (ru) 2003-02-10
SK283734B6 (sk) 2003-12-02
WO1998056773A1 (en) 1998-12-17
JP3672575B2 (ja) 2005-07-20
HK1028242A1 (en) 2001-02-09
TR199801631T1 (xx) 1999-06-21
CO4940452A1 (es) 2000-07-24
PL191943B1 (pl) 2006-07-31
IL125732A0 (en) 1999-04-11
SK109398A3 (en) 1998-12-02
CA2614926C (en) 2010-02-09
US20010037029A1 (en) 2001-11-01
FR07C0037I1 (nl) 2007-08-17
AU8437298A (en) 1998-12-30
NO329314B1 (no) 2010-09-27
US20030125568A1 (en) 2003-07-03
US6740669B1 (en) 2004-05-25
JP2000516259A (ja) 2000-12-05
DK0994863T3 (da) 2003-05-26
TW526195B (en) 2003-04-01
NO983666L (no) 1998-12-17
NO983666D0 (no) 1998-08-11
SK109498A3 (en) 1998-12-02
CZ292481B6 (cs) 2003-09-17
HUP0002113A3 (en) 2002-09-30
ID21014A (id) 1999-04-08
KR19990087836A (ko) 1999-12-27
WO1998056772A1 (en) 1998-12-17
NZ331371A (en) 2000-08-25
SI0994863T1 (en) 2003-08-31
ZA984966B (en) 1999-01-11
BR9804947A (pt) 1999-08-24
DE69811500D1 (de) 2003-03-27
PE79799A1 (es) 1999-09-03
IL125733A0 (en) 1999-04-11
NO983667L (no) 1998-12-17
ATE232852T1 (de) 2003-03-15
CY2007014I2 (el) 2009-11-04
TW403740B (en) 2000-09-01
EP0994863A1 (en) 2000-04-26
AU8437198A (en) 1998-12-30
CA2256013A1 (en) 1998-12-17
PL330764A1 (en) 1999-05-24
EP0994863B1 (en) 2003-02-19
CZ253498A3 (cs) 1999-04-14
AR061005A2 (es) 2008-07-30
IL125733A (en) 2002-12-01
HUP0000798A2 (hu) 2000-10-30
CY2007014I1 (el) 2009-11-04
RU2194041C2 (ru) 2002-12-10
ES2192779T3 (es) 2003-10-16
AR061004A2 (es) 2008-07-30
CO4940448A1 (es) 2000-07-24
HUP0000798A3 (en) 2000-10-30
HK1028241A1 (en) 2001-02-09
KR100409168B1 (ko) 2004-01-31
PT994864E (pt) 2003-07-31
HU225153B1 (en) 2006-07-28
CZ292260B6 (cs) 2003-08-13
CN1217716A (zh) 1999-05-26
AU725528B2 (en) 2000-10-12
DE122007000051I2 (de) 2009-02-19
NO329315B1 (no) 2010-09-27
US7750028B2 (en) 2010-07-06
KR100425656B1 (ko) 2004-05-17
AR012945A1 (es) 2000-11-22
BR9804946A (pt) 1999-08-24
EP0994864B1 (en) 2003-04-16
CA2256015A1 (en) 1998-12-17
JP2000516258A (ja) 2000-12-05
CN1572789A (zh) 2005-02-02
US20100310655A1 (en) 2010-12-09
IL125732A (en) 2002-12-01
NL300284I1 (nl) 2007-10-01
NO983667D0 (no) 1998-08-11
ZA984967B (en) 1999-01-11
FR07C0037I2 (nl) 2008-05-16
PL192114B1 (pl) 2006-08-31
AR012946A1 (es) 2000-11-22
ID27660A (id) 2001-04-19
DE122007000051I1 (de) 2007-11-08
HUP0002113A2 (hu) 2001-02-28
NZ331370A (en) 2000-08-25
MY125854A (en) 2006-08-30
KR19990087835A (ko) 1999-12-27
NL300284I2 (nl) 2007-11-01
HU226107B1 (en) 2008-04-28
DE69813560D1 (de) 2003-05-22
MY120156A (en) 2005-09-30
CA2256013C (en) 2007-10-16
US8076362B2 (en) 2011-12-13
CN1259127A (zh) 2000-07-05
US20040167186A1 (en) 2004-08-26

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SPCM Change of validity term of an spc as amended by art. 17 (2) of ec reg. no. 1610/96 and art. 18 of ec reg. no. 469/2009

Free format text: FIRST REGISTRATION NO/DATE: EU/1/06/378/001, EU/1/06/378/002, EU/1/06/378/003, EU/1/06/378/004, EU/1/06/378/005, EU/1/06/378/006, EU/1/06/378/007, EU/1/06/378/008, EU/1/06/378/009, EU/1/06/378/010, EU/1/06/378/011, EU/1/06/378/012, EU/1/06/378/013, EU/1/06/378/014, EU/1/06/378/015, 20070116

Spc suppl protection certif: 63 5005-2007

Filing date: 20070716

Extension date: 20220118

MK4A Patent expired

Expiry date: 20180608