SK283330B6 - Použitie flupirtínu na prípravu farmaceutického prostriedku - Google Patents

Použitie flupirtínu na prípravu farmaceutického prostriedku Download PDF

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Publication number
SK283330B6
SK283330B6 SK214-96A SK21496A SK283330B6 SK 283330 B6 SK283330 B6 SK 283330B6 SK 21496 A SK21496 A SK 21496A SK 283330 B6 SK283330 B6 SK 283330B6
Authority
SK
Slovakia
Prior art keywords
flupirtine
reflex
preparation
pharmaceutical composition
treatment
Prior art date
Application number
SK214-96A
Other languages
English (en)
Slovak (sk)
Other versions
SK21496A3 (en
Inventor
Michael Schwarz
Gabriela Pergande
J�Rgen Engel
Bernd Nickel
Heinz Ulrich
Stefan Szelenyi
Original Assignee
Viatris Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viatris Gmbh & Co. Kg filed Critical Viatris Gmbh & Co. Kg
Publication of SK21496A3 publication Critical patent/SK21496A3/sk
Publication of SK283330B6 publication Critical patent/SK283330B6/sk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Confectionery (AREA)
SK214-96A 1993-08-17 1994-08-10 Použitie flupirtínu na prípravu farmaceutického prostriedku SK283330B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4327516A DE4327516A1 (de) 1993-08-17 1993-08-17 Primäre und sekundäre neuroprotektive Wirkung bei neurodegenerativen Erkrankungen von Flupirtin
PCT/EP1994/002649 WO1995005175A1 (fr) 1993-08-17 1994-08-10 Effet neuroprotecteur primaire et secondaire de la flupirtine dans le cadre des maladies neurodegeneratives

Publications (2)

Publication Number Publication Date
SK21496A3 SK21496A3 (en) 1997-01-08
SK283330B6 true SK283330B6 (sk) 2003-06-03

Family

ID=6495312

Family Applications (1)

Application Number Title Priority Date Filing Date
SK214-96A SK283330B6 (sk) 1993-08-17 1994-08-10 Použitie flupirtínu na prípravu farmaceutického prostriedku

Country Status (27)

Country Link
US (1) US5721258A (fr)
EP (1) EP0716602B1 (fr)
JP (1) JPH09501664A (fr)
KR (1) KR100341952B1 (fr)
CN (1) CN1086291C (fr)
AT (1) ATE210442T1 (fr)
AU (1) AU694447B2 (fr)
BG (1) BG62430B1 (fr)
BR (1) BR9407293A (fr)
CA (1) CA2169718C (fr)
CZ (1) CZ289040B6 (fr)
DE (2) DE4327516A1 (fr)
DK (1) DK0716602T3 (fr)
EE (1) EE03204B1 (fr)
ES (1) ES2168309T3 (fr)
HR (1) HRP940464A2 (fr)
HU (1) HU227765B1 (fr)
IL (1) IL110681A (fr)
NO (1) NO309842B1 (fr)
NZ (1) NZ273292A (fr)
PT (1) PT716602E (fr)
RU (1) RU2166318C2 (fr)
SK (1) SK283330B6 (fr)
UA (1) UA43351C2 (fr)
WO (1) WO1995005175A1 (fr)
YU (1) YU49215B (fr)
ZA (1) ZA946176B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19539861A1 (de) * 1995-10-26 1997-04-30 Asta Medica Ag Verwendung von 4-Amino-4-(4-fluorbenzylamino)-1-ethoxy-carbonylaminobenzen zur Prophylaxe und Behandlung der Folgen der akuten und chronischen zerebralen Minderdurchblutung sowie neurodegenerativer Erkrankungen
DE19541405A1 (de) * 1995-11-07 1997-05-15 Asta Medica Ag Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen, die mit einer Beeinträchtigung des hämatopoetischen Zellsystems einhergehen
DE19625582A1 (de) * 1996-06-27 1998-01-02 Asta Medica Ag Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen die mit einer unphysiologisch hohen Zellsterberate einhergehen
EP1034783B1 (fr) * 1997-10-27 2004-12-15 Sumitomo Pharmaceuticals Company, Limited Derives d'amide pour le traitement des maladies neurodegeneratives de la retina
AU1359801A (en) * 1999-11-05 2001-06-06 Vela Pharmaceuticals Inc. Methods and compositions for treating reward deficiency syndrome
WO2001039760A2 (fr) * 1999-12-01 2001-06-07 Duke University Methode de traitement de la maladie de batten
US6821995B1 (en) 1999-12-01 2004-11-23 Duke University Method of treating batten disease
DE10327674A1 (de) 2003-06-20 2005-01-05 Awd.Pharma Gmbh & Co. Kg Injizierbare Darreichungsform von Flupirtin
DE10328260A1 (de) * 2003-06-23 2005-01-27 Schmidt, K.-G., Dr. med. Flupirtine-Präparat
CN1917876A (zh) * 2003-12-16 2007-02-21 Cns生物有限公司 方法和组合物
EP1831170A4 (fr) * 2004-12-14 2009-10-14 Astrazeneca Ab Aminopyridines substituees et utilisations
EP1688141A1 (fr) 2005-01-31 2006-08-09 elbion AG Utilisation de flupirtine pour le traitement de la vessie hyperactive et des maladies associées et pour le traitement du syndrome du colon irritable
US20060258708A1 (en) * 2005-05-16 2006-11-16 Andrulis Peter J Jr Method for treating Parkinson's disease and other neurological diseases
US20080279930A1 (en) * 2007-05-07 2008-11-13 Bernd Terhaag Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof
DE102011006425A1 (de) 2010-03-31 2011-10-06 Awd.Pharma Gmbh & Co. Kg Pharmazeutische Zubereitung und deren Verwendung
DE102010030053A1 (de) 2010-06-14 2011-12-15 Awd.Pharma Gmbh & Co.Kg Injizierbare Darreichungsform von Flupirtin
EP3027188A4 (fr) * 2013-07-31 2017-03-01 Teva Pharmaceutical Industries Ltd. Traitement de la sclérose en plaques par combinaison de laquinimode et de flupirtine
US11369593B2 (en) * 2017-07-14 2022-06-28 Texas Tech University System Functionalized pyridine carbamates with enhanced neuroprotective activity
DE102017007385A1 (de) 2017-08-02 2019-02-07 Christoph Hoock Maleatfreie feste Arzneimittelformen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4481205A (en) * 1980-09-13 1984-11-06 Degussa Aktiengesellschaft 2-Amino-3-carbethoxyamino-6-(p-fluoro-benzylamino)-pyridine-maleate
ATE25078T1 (de) * 1982-10-27 1987-02-15 Degussa 2-amino-3-acylamino-6-benzylamino-pyridinderivate mit anti-epileptischer wirkung.
DE3337593A1 (de) * 1982-10-27 1984-05-03 Degussa Ag, 6000 Frankfurt 2-amino-3-acylamino-6-benzylamino-pyridin-derivate mit antiepileptischer wirkung
NO860825L (no) * 1985-03-23 1986-09-24 Degussa Fremgangsmaate til fremstilling av 2-amino-3-nitro-6-(4-fluor-benzylamino)-pyridin samt 2-amino-3-karbetoksyamino-6-(4-fluor-benzylamino)-pyridin.
IN172468B (fr) * 1990-07-14 1993-08-14 Asta Medica Ag

Also Published As

Publication number Publication date
WO1995005175A1 (fr) 1995-02-23
HU227765B1 (en) 2012-02-28
HUT75650A (en) 1997-05-28
RU2166318C2 (ru) 2001-05-10
NZ273292A (en) 1999-09-29
UA43351C2 (uk) 2001-12-17
KR100341952B1 (ko) 2003-04-11
CZ46596A3 (en) 1996-05-15
BR9407293A (pt) 1996-10-01
IL110681A0 (en) 1994-11-11
CA2169718A1 (fr) 1995-02-23
YU51294A (sh) 1998-05-15
HU9600355D0 (en) 1996-04-29
NO960607L (no) 1996-02-15
CN1086291C (zh) 2002-06-19
CZ289040B6 (cs) 2001-10-17
KR960703591A (ko) 1996-08-31
DE4327516A1 (de) 1995-02-23
PT716602E (pt) 2002-05-31
DE69429435D1 (de) 2002-01-24
HRP940464A2 (en) 1997-06-30
CA2169718C (fr) 2002-11-12
BG100356A (bg) 1996-07-31
ZA946176B (en) 1995-03-20
AU694447B2 (en) 1998-07-23
JPH09501664A (ja) 1997-02-18
EP0716602B1 (fr) 2001-12-12
DK0716602T3 (da) 2002-03-25
EP0716602A1 (fr) 1996-06-19
NO960607D0 (no) 1996-02-15
AU7652894A (en) 1995-03-14
CN1129399A (zh) 1996-08-21
DE69429435T2 (de) 2002-06-13
YU49215B (sh) 2004-11-25
IL110681A (en) 1999-08-17
US5721258A (en) 1998-02-24
EE03204B1 (et) 1999-08-16
NO309842B1 (no) 2001-04-09
ATE210442T1 (de) 2001-12-15
ES2168309T3 (es) 2002-06-16
SK21496A3 (en) 1997-01-08
BG62430B1 (bg) 1999-11-30

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Expiry date: 20140810