IN172468B - - Google Patents

Info

Publication number
IN172468B
IN172468B IN421CA1991A IN172468B IN 172468 B IN172468 B IN 172468B IN 421CA1991 A IN421CA1991 A IN 421CA1991A IN 172468 B IN172468 B IN 172468B
Authority
IN
India
Prior art keywords
flupirtine
disorders
compound
treatment
relates
Prior art date
Application number
Other languages
English (en)
Inventor
Michael Dr Lobisch
Ralph Dr Venhaus
Bernd Dr Nickel
Istvan Prof Szelenyi
Juergen Prof Engel
Peter Dr Emig
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Priority to IN421CA1991 priority Critical patent/IN172468B/en
Priority to ES95101189T priority patent/ES2164111T3/es
Priority to DE4122166A priority patent/DE4122166A1/de
Priority to DE59109222T priority patent/DE59109222D1/de
Priority to AT95101189T priority patent/ATE206919T1/de
Priority to EP95101189A priority patent/EP0659410B1/fr
Priority to EP91111124A priority patent/EP0467164B1/fr
Priority to DK91111124.3T priority patent/DK0467164T3/da
Priority to AT91111124T priority patent/ATE133564T1/de
Priority to DE59107331T priority patent/DE59107331D1/de
Priority to ES91111124T priority patent/ES2082887T3/es
Priority to DK95101189T priority patent/DK0659410T3/da
Priority to MC912203A priority patent/MC2272A1/fr
Priority to CS912101A priority patent/CZ280879B6/cs
Priority to SK2101-91A priority patent/SK279567B6/sk
Priority to RO147972A priority patent/RO108220B1/ro
Priority to EG41291A priority patent/EG19814A/xx
Priority to MX9100160A priority patent/MX9100160A/es
Priority to US07/726,408 priority patent/US5162346A/en
Priority to PT98291A priority patent/PT98291B/pt
Priority to NO91912758A priority patent/NO912758L/no
Priority to CA002046943A priority patent/CA2046943C/fr
Priority to IL9881091A priority patent/IL98810A/en
Priority to SU915001150A priority patent/RU2070408C1/ru
Priority to SI9111227A priority patent/SI9111227B/sl
Priority to ZA915466A priority patent/ZA915466B/xx
Priority to NZ238940A priority patent/NZ238940A/en
Priority to IE245191A priority patent/IE74688B1/en
Priority to AU80403/91A priority patent/AU634073B2/en
Priority to HU912359A priority patent/HU206973B/hu
Priority to CN91104030A priority patent/CN1070700C/zh
Priority to KR1019910011967A priority patent/KR0182811B1/ko
Priority to US07/890,730 priority patent/US5284861A/en
Priority to HRP-1227/91A priority patent/HRP920667B1/xx
Priority to LVP-92-173A priority patent/LV10048B/lv
Publication of IN172468B publication Critical patent/IN172468B/en
Priority to LTIP919A priority patent/LT3593B/lt
Priority to GR960400581T priority patent/GR3019179T3/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Golf Clubs (AREA)
  • Details Of Television Scanning (AREA)
  • Paints Or Removers (AREA)
IN421CA1991 1990-07-14 1991-06-04 IN172468B (fr)

Priority Applications (37)

Application Number Priority Date Filing Date Title
IN421CA1991 IN172468B (fr) 1990-07-14 1991-06-04
ES95101189T ES2164111T3 (es) 1990-07-14 1991-07-04 Empleo del principio activo flupirtina para la preparacion de un medicamento para combatir espasmos musculares.
DE4122166A DE4122166A1 (de) 1990-07-14 1991-07-04 Verwendung des wirkstoffs flupirtin zur bekaempfung von muskelverspannungen
DE59109222T DE59109222D1 (de) 1990-07-14 1991-07-04 Verwendung des Wirkstoffs Flupirtin zur Herstellung eines Arzneimittels zur Bekämpfung von Muskelverspannungen
AT95101189T ATE206919T1 (de) 1990-07-14 1991-07-04 Verwendung des wirkstoffs flupirtin zur herstellung eines arzneimittels zur bekämpfung von muskelverspannungen
EP95101189A EP0659410B1 (fr) 1990-07-14 1991-07-04 Utilisation du composé flupirtin pour la préparation d'un medicament pour lutter contre la raideur musculaire
EP91111124A EP0467164B1 (fr) 1990-07-14 1991-07-04 Flupirtine en combinaison avec antiparkinsonica pour lutter contre la raideur musculaire
DK91111124.3T DK0467164T3 (da) 1990-07-14 1991-07-04 Anvendelse af det virksomme stof flupirtin i kombination med antiparkinsonika til bekæmpelse af muskelspændinger
AT91111124T ATE133564T1 (de) 1990-07-14 1991-07-04 Flupirtin in kombination mit antiparkinsonika zur bekämpfung von muskelverspannungen
DE59107331T DE59107331D1 (de) 1990-07-14 1991-07-04 Flupirtin in Kombination mit Antiparkinsonika zur Bekämpfung von Muskelverspannungen
ES91111124T ES2082887T3 (es) 1990-07-14 1991-07-04 Flupirtina en combinacion con antiparkinsonianos para combatir espasmos musculares.
DK95101189T DK0659410T3 (da) 1990-07-14 1991-07-04 Anvendelse af det aktive middel flupirtin til fremstilling af et lægemiddel til bekæmpelse af muskelspændinger
MC912203A MC2272A1 (fr) 1990-07-14 1991-07-05 Utilisation de la substance active nommee flupirtine pour combattre des contractures musculaires
CS912101A CZ280879B6 (cs) 1990-07-14 1991-07-08 Použití účinné látky flupirtinu pro odstranení svalového přepětí
SK2101-91A SK279567B6 (sk) 1990-07-14 1991-07-08 Použitie flupirtínu alebo jeho terapeuticky zhodno
RO147972A RO108220B1 (ro) 1990-07-14 1991-07-09 Preparate farmaceutice,pentru combaterea carceilor musculari si procedeu de obtinere a acestora
EG41291A EG19814A (en) 1990-07-14 1991-07-09 A process for thr preparation of an agent with the active substance flupirtine to combat muscular tension and the use of flupirtine for such purpose
MX9100160A MX9100160A (es) 1990-07-14 1991-07-10 Procedimiento para preparar un medicamento que contiene flupirtina como sustancia activa para combatir contracturas musculares
US07/726,408 US5162346A (en) 1990-07-14 1991-07-10 Pharmaceutical composition comprising flupirtine and its use to combat muscular tension
PT98291A PT98291B (pt) 1990-07-14 1991-07-11 Processo para a preparacao de composicoes farmaceuticas contendo flupirtina para combater distensoes musculares
AU80403/91A AU634073B2 (en) 1990-07-14 1991-07-12 A process for the preparation of an agent with the active substance flupirtine to combat muscular tension and the use of flupirtine for such purpose
HU912359A HU206973B (en) 1990-07-14 1991-07-12 Process for producing pharmaceutical compositions comprising flupirin as active ingredient
IL9881091A IL98810A (en) 1990-07-14 1991-07-12 Pharmaceuticals containing flopirtin against disorders of muscle tension and their preparation
SU915001150A RU2070408C1 (ru) 1990-07-14 1991-07-12 Средство, уменьшающее мышечную регидность, и средство для лечения болезни паркинсона
SI9111227A SI9111227B (sl) 1990-07-14 1991-07-12 Farmacevtski preprat z aktivno materijo Flupirtin za zdravljenje bolezni, ki se nanašajo na napetost mišic
ZA915466A ZA915466B (en) 1990-07-14 1991-07-12 A process for the preparation of an agent with the active substance flupirtine to combat muscular tension and the use of flupirtine for such purpose
NZ238940A NZ238940A (en) 1990-07-14 1991-07-12 Pharmaceutical compositions containing flupirtine and an antiparkinson agent; the use of flupirtine in the manufacture of a medicament to combat muscular tension
IE245191A IE74688B1 (en) 1990-07-14 1991-07-12 Flupirtine in combination with antiparkinsonica against muscle bracing
NO91912758A NO912758L (no) 1990-07-14 1991-07-12 Anvendelse av det virksomme stoffet flupirtin for bekjempelse av muskelspenninger.
CA002046943A CA2046943C (fr) 1990-07-14 1991-07-12 Procede de production d'un agent ayant comme substance active de la flupirtine et visant a soulager la tension musculaire
CN91104030A CN1070700C (zh) 1990-07-14 1991-07-13 含氟吡氨酯药物的制备方法及其在治疗肌紧张中的应用
KR1019910011967A KR0182811B1 (ko) 1990-07-14 1991-07-13 근육긴장을 억제하기 위한 활성물질 플루피르틴-함유 약제 및 이의 제조방법
US07/890,730 US5284861A (en) 1990-07-14 1992-06-01 Pharmaceutical composition comprising flupirtine and its use to combat Parkinson disorders
HRP-1227/91A HRP920667B1 (en) 1990-07-14 1992-09-30 Application of fultripine active substance for preventing muscle deformation
LVP-92-173A LV10048B (en) 1990-07-14 1992-10-27 Medical agent and method for producing thereof
LTIP919A LT3593B (en) 1990-07-14 1993-09-03 Drugs and process for preparing thereof
GR960400581T GR3019179T3 (en) 1990-07-14 1996-03-05 Flupirtine in combination with antiparkinsonica against muscle bracing

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4022442 1990-07-14
IN421CA1991 IN172468B (fr) 1990-07-14 1991-06-04

Publications (1)

Publication Number Publication Date
IN172468B true IN172468B (fr) 1993-08-14

Family

ID=25895002

Family Applications (1)

Application Number Title Priority Date Filing Date
IN421CA1991 IN172468B (fr) 1990-07-14 1991-06-04

Country Status (30)

Country Link
US (2) US5162346A (fr)
EP (2) EP0659410B1 (fr)
KR (1) KR0182811B1 (fr)
CN (1) CN1070700C (fr)
AT (2) ATE206919T1 (fr)
AU (1) AU634073B2 (fr)
CA (1) CA2046943C (fr)
CZ (1) CZ280879B6 (fr)
DE (3) DE59107331D1 (fr)
DK (2) DK0467164T3 (fr)
EG (1) EG19814A (fr)
ES (2) ES2082887T3 (fr)
GR (1) GR3019179T3 (fr)
HR (1) HRP920667B1 (fr)
HU (1) HU206973B (fr)
IE (1) IE74688B1 (fr)
IL (1) IL98810A (fr)
IN (1) IN172468B (fr)
LT (1) LT3593B (fr)
LV (1) LV10048B (fr)
MC (1) MC2272A1 (fr)
MX (1) MX9100160A (fr)
NO (1) NO912758L (fr)
NZ (1) NZ238940A (fr)
PT (1) PT98291B (fr)
RO (1) RO108220B1 (fr)
RU (1) RU2070408C1 (fr)
SI (1) SI9111227B (fr)
SK (1) SK279567B6 (fr)
ZA (1) ZA915466B (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0560092B1 (fr) * 1992-03-11 1997-12-03 ASTA Medica Aktiengesellschaft Tablettes, granules et pilules à teneur élevée en principes actifs pour formes d'administration solides à haute concentration
DE4319649A1 (de) * 1993-03-18 1994-09-22 Asta Medica Ag Feste Flupirtin enthaltende orale Darreichungsformen mit kontrollierter Wirkstoffabgabe
DE4327516A1 (de) * 1993-08-17 1995-02-23 Asta Medica Ag Primäre und sekundäre neuroprotektive Wirkung bei neurodegenerativen Erkrankungen von Flupirtin
GB9426079D0 (en) * 1994-12-23 1995-02-22 Orion Yhtymae Oy A gelatine capsule
DE19541405A1 (de) * 1995-11-07 1997-05-15 Asta Medica Ag Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen, die mit einer Beeinträchtigung des hämatopoetischen Zellsystems einhergehen
US6284794B1 (en) 1996-11-05 2001-09-04 Head Explorer Aps Method for treating tension-type headache with inhibitors of nitric oxide and nitric oxide synthase
US6610324B2 (en) * 1999-04-07 2003-08-26 The Mclean Hospital Corporation Flupirtine in the treatment of fibromyalgia and related conditions
HUP0301296A2 (hu) * 1999-08-03 2003-08-28 Awd.Pharma Gmbh & Co. Kg Flupirtin alkalmazása degeneratív ízületi fájdalom kezelésére
US6821995B1 (en) 1999-12-01 2004-11-23 Duke University Method of treating batten disease
US20040122090A1 (en) * 2001-12-07 2004-06-24 Lipton Stuart A. Methods for treating neuropsychiatric disorders with nmda receptor antagonists
RU2213565C1 (ru) * 2002-06-24 2003-10-10 Общество с ограниченной ответственностью "Паркинфарм" Способ лечебного воздействия на организм пациента при лечении болезни паркинсона
DE10255415A1 (de) * 2002-11-28 2004-06-09 Bayer Healthcare Ag Dermale Applikation von Flupirtin
DE10327674A1 (de) 2003-06-20 2005-01-05 Awd.Pharma Gmbh & Co. Kg Injizierbare Darreichungsform von Flupirtin
US20050089559A1 (en) 2003-10-23 2005-04-28 Istvan Szelenyi Combinations of potassium channel openers and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains
DE102004001558A1 (de) * 2004-01-10 2005-08-18 Bayer Healthcare Ag Arzneimittel zur topischen Applikation bei Tieren
US20050196461A1 (en) * 2004-01-14 2005-09-08 Udell Ronald G. Ceramide formulations suitable for oral administration
WO2005072705A1 (fr) * 2004-01-29 2005-08-11 Neuromolecular, Inc. Combinaison d'antagoniste de recepteur nmda et d'inhibiteur mao ou gadpf pour le traitement d'affections liees au systeme nerveux central
US20050220862A1 (en) * 2004-03-31 2005-10-06 Bernstein Joel E Compositions with reduced hepatotoxicity
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
EP1688141A1 (fr) * 2005-01-31 2006-08-09 elbion AG Utilisation de flupirtine pour le traitement de la vessie hyperactive et des maladies associées et pour le traitement du syndrome du colon irritable
DE602006016934D1 (de) * 2005-04-06 2010-10-28 Adamas Pharmaceuticals Inc Verfahren und zusammensetzungen zur behandlung von zns-erkrankungen
CA2650853A1 (fr) * 2006-05-02 2007-11-15 Chris Rundfeldt Activateurs de canaux potassiques pour la prevention et le traitement de la dystonie et des systemes assimiles a la dystonie
US7960436B2 (en) 2006-06-05 2011-06-14 Valeant Pharmaceuticals International Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators
US8993593B2 (en) * 2006-08-23 2015-03-31 Valeant Pharmaceuticals International N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators
MX2009002002A (es) * 2006-08-23 2009-07-22 Valeant Pharmaceuticals Int Derivados de 4-(n-azacicloalquil) anilidas como moduladores de canal de potasio.
US8722929B2 (en) * 2006-10-10 2014-05-13 Valeant Pharmaceuticals International N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators
MX2009005652A (es) * 2006-11-28 2009-08-07 Valeant Pharmaceuticals Int Analogos 1,4 diamino biciclicos de retigabina como moduladores de canales de potasio.
US20080279930A1 (en) * 2007-05-07 2008-11-13 Bernd Terhaag Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
CA2694887A1 (fr) * 2007-08-01 2009-02-05 Henriette Husum Bak-Jensen Utilisation d'agents d'ouverture kncq des canaux potassiques pour reduire des symptomes ou traiter des troubles et des etats dans lesquels le systeme dopaminergique est detruit
US8563566B2 (en) * 2007-08-01 2013-10-22 Valeant Pharmaceuticals International Naphthyridine derivatives as potassium channel modulators
US7786146B2 (en) * 2007-08-13 2010-08-31 Valeant Pharmaceuticals International Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
ES2347119B2 (es) * 2009-04-22 2011-04-28 Universidad De Santiago De Compostela Nanocapsulas de poliarginina.
DE102010030053A1 (de) 2010-06-14 2011-12-15 Awd.Pharma Gmbh & Co.Kg Injizierbare Darreichungsform von Flupirtin
JP6251667B2 (ja) * 2014-06-03 2017-12-20 アサヒカルピスウェルネス株式会社 錠剤型即放性製剤及びその製造方法
DE102017007385A1 (de) 2017-08-02 2019-02-07 Christoph Hoock Maleatfreie feste Arzneimittelformen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795858C2 (de) 1968-07-19 1979-01-11 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Benzylaminopyridine
DE3133519A1 (de) 1980-09-13 1982-06-09 Degussa Ag, 6000 Frankfurt "2-amino-3-carbethoxyamino-6-(p-fluor-benzylamino)-pyridin-maleat"
DE3665538D1 (en) * 1985-01-23 1989-10-19 Asta Pharma Ag Synergistic combination of flupirtin and non-steroidal anti-phlogistics
DE3604575A1 (de) 1985-02-23 1986-08-28 Degussa Ag, 6000 Frankfurt Kombination von flupirtin und anticholinergisch wirkenden spasmolytika
ATE43789T1 (de) * 1985-02-23 1989-06-15 Asta Pharma Ag Kombination von flupirtin und anticholinergisch wirkenden spasmolytika.
FI855016A (fi) * 1985-06-28 1986-12-29 Degussa Synergistisk kombination av flupirtin och 4-acetamido-fenol.

Also Published As

Publication number Publication date
HRP920667B1 (en) 1998-06-30
IL98810A (en) 1996-01-19
HU206973B (en) 1993-03-01
US5162346A (en) 1992-11-10
HRP920667A2 (en) 1996-10-31
KR0182811B1 (ko) 1999-05-01
EP0467164A3 (en) 1992-04-15
DK0659410T3 (da) 2001-12-27
PT98291B (pt) 1999-01-29
ZA915466B (en) 1992-04-29
MC2272A1 (fr) 1993-06-23
DK0467164T3 (da) 1996-03-04
MX9100160A (es) 1992-02-28
CN1070700C (zh) 2001-09-12
ATE206919T1 (de) 2001-11-15
CZ280879B6 (cs) 1996-04-17
SI9111227B (sl) 2000-12-31
ES2164111T3 (es) 2002-02-16
SI9111227A (en) 1995-06-30
GR3019179T3 (en) 1996-06-30
SK279567B6 (sk) 1999-01-11
CS210191A3 (en) 1992-02-19
ES2082887T3 (es) 1996-04-01
IE74688B1 (en) 1997-07-30
EP0659410A2 (fr) 1995-06-28
IL98810A0 (en) 1992-07-15
CA2046943C (fr) 1996-03-12
HU912359D0 (en) 1991-12-30
LV10048A (lv) 1994-05-10
ATE133564T1 (de) 1996-02-15
NO912758L (no) 1992-01-15
DE59107331D1 (de) 1996-03-14
EP0659410A3 (fr) 1995-10-25
US5284861A (en) 1994-02-08
EG19814A (en) 1996-02-29
RU2070408C1 (ru) 1996-12-20
AU8040391A (en) 1992-01-16
LV10048B (en) 1995-06-20
LTIP919A (en) 1995-03-27
DE59109222D1 (de) 2001-11-22
NO912758D0 (no) 1991-07-12
CN1058716A (zh) 1992-02-19
EP0467164B1 (fr) 1996-01-31
LT3593B (en) 1995-12-27
EP0659410B1 (fr) 2001-10-17
HUT59313A (en) 1992-05-28
IE912451A1 (en) 1992-01-15
RO108220B1 (ro) 1994-03-31
AU634073B2 (en) 1993-02-11
DE4122166A1 (de) 1992-01-16
EP0467164A2 (fr) 1992-01-22
NZ238940A (en) 1997-05-26
PT98291A (pt) 1992-05-29
CA2046943A1 (fr) 1992-01-15
KR920002147A (ko) 1992-02-28

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