PT98291A - Processo para a preparacao de composicoes farmaceuticas contendo flupirtina para combater distensoes musculares - Google Patents

Processo para a preparacao de composicoes farmaceuticas contendo flupirtina para combater distensoes musculares

Info

Publication number
PT98291A
PT98291A PT98291A PT9829191A PT98291A PT 98291 A PT98291 A PT 98291A PT 98291 A PT98291 A PT 98291A PT 9829191 A PT9829191 A PT 9829191A PT 98291 A PT98291 A PT 98291A
Authority
PT
Portugal
Prior art keywords
flupirty
distensions
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
PT98291A
Other languages
English (en)
Other versions
PT98291B (pt
Inventor
Juergen Engel
Michael Lobisch
Ralph Venhaus
Bernd Nickel
Istvan Szelenyi
Peter Emig
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of PT98291A publication Critical patent/PT98291A/pt
Publication of PT98291B publication Critical patent/PT98291B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Golf Clubs (AREA)
  • Details Of Television Scanning (AREA)
  • Paints Or Removers (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Plant Substances (AREA)
PT98291A 1990-07-14 1991-07-11 Processo para a preparacao de composicoes farmaceuticas contendo flupirtina para combater distensoes musculares PT98291B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4022442 1990-07-14
IN421CA1991 IN172468B (pt) 1990-07-14 1991-06-04

Publications (2)

Publication Number Publication Date
PT98291A true PT98291A (pt) 1992-05-29
PT98291B PT98291B (pt) 1999-01-29

Family

ID=25895002

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98291A PT98291B (pt) 1990-07-14 1991-07-11 Processo para a preparacao de composicoes farmaceuticas contendo flupirtina para combater distensoes musculares

Country Status (30)

Country Link
US (2) US5162346A (pt)
EP (2) EP0659410B1 (pt)
KR (1) KR0182811B1 (pt)
CN (1) CN1070700C (pt)
AT (2) ATE133564T1 (pt)
AU (1) AU634073B2 (pt)
CA (1) CA2046943C (pt)
CZ (1) CZ280879B6 (pt)
DE (3) DE59109222D1 (pt)
DK (2) DK0659410T3 (pt)
EG (1) EG19814A (pt)
ES (2) ES2164111T3 (pt)
GR (1) GR3019179T3 (pt)
HR (1) HRP920667B1 (pt)
HU (1) HU206973B (pt)
IE (1) IE74688B1 (pt)
IL (1) IL98810A (pt)
IN (1) IN172468B (pt)
LT (1) LT3593B (pt)
LV (1) LV10048B (pt)
MC (1) MC2272A1 (pt)
MX (1) MX9100160A (pt)
NO (1) NO912758L (pt)
NZ (1) NZ238940A (pt)
PT (1) PT98291B (pt)
RO (1) RO108220B1 (pt)
RU (1) RU2070408C1 (pt)
SI (1) SI9111227B (pt)
SK (1) SK279567B6 (pt)
ZA (1) ZA915466B (pt)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE160696T1 (de) * 1992-03-11 1997-12-15 Asta Medica Ag Tabletten, granulate und pellets mit hohem gehalt an wirkstoffen für hochkonzentrierte, feste darreichungsformen
DE4319649A1 (de) * 1993-03-18 1994-09-22 Asta Medica Ag Feste Flupirtin enthaltende orale Darreichungsformen mit kontrollierter Wirkstoffabgabe
DE4327516A1 (de) * 1993-08-17 1995-02-23 Asta Medica Ag Primäre und sekundäre neuroprotektive Wirkung bei neurodegenerativen Erkrankungen von Flupirtin
GB9426079D0 (en) * 1994-12-23 1995-02-22 Orion Yhtymae Oy A gelatine capsule
DE19541405A1 (de) * 1995-11-07 1997-05-15 Asta Medica Ag Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen, die mit einer Beeinträchtigung des hämatopoetischen Zellsystems einhergehen
US6284794B1 (en) 1996-11-05 2001-09-04 Head Explorer Aps Method for treating tension-type headache with inhibitors of nitric oxide and nitric oxide synthase
US6610324B2 (en) * 1999-04-07 2003-08-26 The Mclean Hospital Corporation Flupirtine in the treatment of fibromyalgia and related conditions
KR20020040767A (ko) * 1999-08-03 2002-05-30 아베데 파르마 게엠베하 운트 콤파니 카게 개와 고양이에서 퇴행성 관절 질환으로 인한 통증을경감시키기 위한 플루피르틴의 용도
US6821995B1 (en) 1999-12-01 2004-11-23 Duke University Method of treating batten disease
US20040122090A1 (en) * 2001-12-07 2004-06-24 Lipton Stuart A. Methods for treating neuropsychiatric disorders with nmda receptor antagonists
RU2213565C1 (ru) * 2002-06-24 2003-10-10 Общество с ограниченной ответственностью "Паркинфарм" Способ лечебного воздействия на организм пациента при лечении болезни паркинсона
DE10255415A1 (de) * 2002-11-28 2004-06-09 Bayer Healthcare Ag Dermale Applikation von Flupirtin
DE10327674A1 (de) * 2003-06-20 2005-01-05 Awd.Pharma Gmbh & Co. Kg Injizierbare Darreichungsform von Flupirtin
US20050089559A1 (en) 2003-10-23 2005-04-28 Istvan Szelenyi Combinations of potassium channel openers and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains
DE102004001558A1 (de) * 2004-01-10 2005-08-18 Bayer Healthcare Ag Arzneimittel zur topischen Applikation bei Tieren
US20050196461A1 (en) * 2004-01-14 2005-09-08 Udell Ronald G. Ceramide formulations suitable for oral administration
EP1715843A1 (en) * 2004-01-29 2006-11-02 Neuromolecular Inc. Combination of a nmda receptor antagonist and a mao-inhibitor or a gadph-inhibitor for the treatment of central nervous system-related conditions
US20050220862A1 (en) * 2004-03-31 2005-10-06 Bernstein Joel E Compositions with reduced hepatotoxicity
US7619007B2 (en) * 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
EP1688141A1 (en) * 2005-01-31 2006-08-09 elbion AG The use of flupirtine for the treatment of overactive bladder and associated diseases, and for the treatment of irritable bowel syndrome
ATE481096T1 (de) 2005-04-06 2010-10-15 Adamas Pharmaceuticals Inc Verfahren und zusammensetzungen zur behandlung von zns-erkrankungen
WO2007128462A1 (en) * 2006-05-02 2007-11-15 Chris Rundfeldt Potassium channel activators for the prevention and treatment of dystonia and dystonia-like symptoms
US7960436B2 (en) 2006-06-05 2011-06-14 Valeant Pharmaceuticals International Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators
SG174095A1 (en) * 2006-08-23 2011-09-29 Valeant Pharmaceuticals Int Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators
US8993593B2 (en) * 2006-08-23 2015-03-31 Valeant Pharmaceuticals International N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators
US8722929B2 (en) * 2006-10-10 2014-05-13 Valeant Pharmaceuticals International N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators
CN101578259A (zh) * 2006-11-28 2009-11-11 威朗国际制药公司 作为钾通道调节剂的1,4-二氨基双环瑞替加滨类似物
US20080279930A1 (en) * 2007-05-07 2008-11-13 Bernd Terhaag Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
AR070513A1 (es) * 2007-08-01 2010-04-14 Lundbeck & Co As H Uso de abridores de canales de potasio kcnq para reducir los sintomas o tratar desordenes o afecciones en las cuales se encuentra anulado el sis-tema dopaminergico como por ejemplo esquizofrenia y trastorno depresivo mayor
US8563566B2 (en) * 2007-08-01 2013-10-22 Valeant Pharmaceuticals International Naphthyridine derivatives as potassium channel modulators
US7786146B2 (en) * 2007-08-13 2010-08-31 Valeant Pharmaceuticals International Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
ES2347119B2 (es) * 2009-04-22 2011-04-28 Universidad De Santiago De Compostela Nanocapsulas de poliarginina.
DE102010030053A1 (de) 2010-06-14 2011-12-15 Awd.Pharma Gmbh & Co.Kg Injizierbare Darreichungsform von Flupirtin
JP6251667B2 (ja) * 2014-06-03 2017-12-20 アサヒカルピスウェルネス株式会社 錠剤型即放性製剤及びその製造方法
DE102017007385A1 (de) 2017-08-02 2019-02-07 Christoph Hoock Maleatfreie feste Arzneimittelformen
TWI886158B (zh) 2019-10-10 2025-06-11 加拿大商再諾製藥公司 選擇性鉀通道調節劑之固態晶型
MX2022005490A (es) 2019-11-08 2022-08-10 Xenon Pharmaceuticals Inc Metodos para el tratamiento de trastornos depresivos.
US11957675B2 (en) 2021-02-09 2024-04-16 Xenon Pharmaceuticals Inc. Methods and uses for treating anhedonia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795858C2 (de) 1968-07-19 1979-01-11 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Benzylaminopyridine
DE3133519A1 (de) 1980-09-13 1982-06-09 Degussa Ag, 6000 Frankfurt "2-amino-3-carbethoxyamino-6-(p-fluor-benzylamino)-pyridin-maleat"
DE3665538D1 (en) * 1985-01-23 1989-10-19 Asta Pharma Ag Synergistic combination of flupirtin and non-steroidal anti-phlogistics
EP0193056B1 (de) * 1985-02-23 1989-06-07 ASTA Pharma Aktiengesellschaft Kombination von Flupirtin und anticholinergisch wirkenden Spasmolytika
DE3604575A1 (de) * 1985-02-23 1986-08-28 Degussa Ag, 6000 Frankfurt Kombination von flupirtin und anticholinergisch wirkenden spasmolytika
FI855016A7 (fi) * 1985-06-28 1986-12-29 Degussa Flupirtiinin ja 4-asetamido-fenolin synergistinen yhdistelmä.

Also Published As

Publication number Publication date
CN1058716A (zh) 1992-02-19
AU634073B2 (en) 1993-02-11
CN1070700C (zh) 2001-09-12
DK0467164T3 (da) 1996-03-04
IL98810A0 (en) 1992-07-15
KR920002147A (ko) 1992-02-28
EP0659410A2 (de) 1995-06-28
HU912359D0 (en) 1991-12-30
EG19814A (en) 1996-02-29
SI9111227A (en) 1995-06-30
US5284861A (en) 1994-02-08
IE912451A1 (en) 1992-01-15
SI9111227B (sl) 2000-12-31
KR0182811B1 (ko) 1999-05-01
HRP920667B1 (en) 1998-06-30
ES2164111T3 (es) 2002-02-16
ES2082887T3 (es) 1996-04-01
EP0659410A3 (de) 1995-10-25
CZ280879B6 (cs) 1996-04-17
RU2070408C1 (ru) 1996-12-20
GR3019179T3 (en) 1996-06-30
IN172468B (pt) 1993-08-14
CA2046943A1 (en) 1992-01-15
DE59107331D1 (de) 1996-03-14
MC2272A1 (fr) 1993-06-23
IE74688B1 (en) 1997-07-30
ZA915466B (en) 1992-04-29
US5162346A (en) 1992-11-10
PT98291B (pt) 1999-01-29
EP0659410B1 (de) 2001-10-17
IL98810A (en) 1996-01-19
LV10048A (lv) 1994-05-10
LV10048B (en) 1995-06-20
ATE206919T1 (de) 2001-11-15
CS210191A3 (en) 1992-02-19
ATE133564T1 (de) 1996-02-15
NO912758L (no) 1992-01-15
DK0659410T3 (da) 2001-12-27
EP0467164A3 (en) 1992-04-15
RO108220B1 (ro) 1994-03-31
CA2046943C (en) 1996-03-12
HU206973B (en) 1993-03-01
LTIP919A (en) 1995-03-27
HUT59313A (en) 1992-05-28
DE4122166A1 (de) 1992-01-16
LT3593B (en) 1995-12-27
MX9100160A (es) 1992-02-28
AU8040391A (en) 1992-01-16
NO912758D0 (no) 1991-07-12
EP0467164B1 (de) 1996-01-31
SK279567B6 (sk) 1999-01-11
DE59109222D1 (de) 2001-11-22
HRP920667A2 (en) 1996-10-31
NZ238940A (en) 1997-05-26
EP0467164A2 (de) 1992-01-22

Similar Documents

Publication Publication Date Title
PT98291A (pt) Processo para a preparacao de composicoes farmaceuticas contendo flupirtina para combater distensoes musculares
UA27911C2 (uk) Засіб для лікування або запобігання фізіологічних розладів, які викликані надлишком тахікініну
PT96871A (pt) Processo para a preparacao de compostos 3-arilcarbonil-1h-indol uteis como agentes terapeuticos
BR9914696A (pt) Composto, processo para tratamento de distúrbio mediado por ciclo-oxigenase-2 em um indivìduo, e, composição farmacêutica
BR8801315A (pt) Tirazolinonas substituidas,processo para sua preparacao,composicoes herbicidas,processo para combater ervas daninhas e para a preparacao de composicoes,compostos e processo para sua preparacao
EP0444196A4 (en) Agent for treatment and prophylaxis of ischemic disease of heart or brain
IL103277A (en) N-alkyl-3-phenyl-3- (2-alkylthiophenoxy) propylamines and pharmaceutical compositions containing them
ES537300A0 (es) Procedimiento para la preparacion de gangliosidos y sus derivados administrables por nebulizacion
IL100874A0 (en) Oxypurine nucleosides and their congeners,and acyl derivatives thereof,for improvement of hematopoiesis
BR8901019A (pt) Sulfonilaminoazois substituidos,processo para sua preparacao,composicao herbicida,processo para combate de ervas daninhas,bem como processo para a preparacao de composicoes herbicidas
BR8801149A (pt) "2,5-dihidropirrois,processo para sua preparacao,composicoes herbicidas,processos para combater ervas daninhas e para a preparacao de composicoes,compostos e processo para sua preparacao
IL111580A (en) Use of melatonin derivatives in the preparation of pharmaceutical compositions for use in treating sleep disorders
BR8703423A (pt) Processo para a preparacao de dialquilmaleinimidas,composicoes herbicidas,processos para o combate de ervas daninhas e para a preparacao de composicoes
PT656209E (pt) Derivados de melatonina para uso no tratamento de perturbacoes de dessincronizacao
MY104521A (en) Treatment of depression.
BR8606328A (pt) Imidazolinonas,composicoes herbicidas,aplicacao,processo para combater ervas daninhas,composicao reguladora do crescimento,processo para a preparacao de compostos
ES533657A0 (es) Un procedimiento para la preparacion de nuevos derivados de pirrolo-(2,1-a)isoquilonina.
BR8700289A (pt) Processo para a preparacao de 2,4-diamino-6-halogenoalquilpirimidinas,composicoes herbicidas,processos para o combate de ervas daninhas e para a preparacao de composicoes
BR8606196A (pt) Processo para a preparacao de pirimidil-mercapto-acilanilidas,composicoes herbicidas,processo para o combate de ervas daninhas e para a preparacao de composicoes
BR9201272A (pt) Compostos,composicoes herbicidas,processos para combater ervas daninhas e para a preparacao de compostos,emprego e processo para a preparacao de composicoes
ES501744A0 (es) Procedimiento para la obtencion de bis (fenoxiacetatos sus- tituidos)de n-alcohil-dialcanolaminas
RU93035807A (ru) Способ лечения юношеского эпифизиолиса
PT7500U (pt) Par de manivelas pedaleiras regulaveis para tratamento ortopedico
IT8023511A0 (it) Composti isoprenoidi azotati adattivita' terapeutica, procedimento per la loro preparazione e relative composizioni terapeutiche.

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920110

FG3A Patent granted, date of granting

Effective date: 19981002

PC3A Transfer or assignment

Free format text: 20020520 AWD. PHARMA GMBH & CO. KG DE

TE3A Change of address (patent)

Owner name: ASTA MEDICA AKTIENGESELLSCHAFT

Effective date: 20020520

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20131002