SK282779B6 - Spôsob prípravy alfa-chlór alebo alfa-fluórketónu - Google Patents

Spôsob prípravy alfa-chlór alebo alfa-fluórketónu Download PDF

Info

Publication number
SK282779B6
SK282779B6 SK328-98A SK32898A SK282779B6 SK 282779 B6 SK282779 B6 SK 282779B6 SK 32898 A SK32898 A SK 32898A SK 282779 B6 SK282779 B6 SK 282779B6
Authority
SK
Slovakia
Prior art keywords
formula
compound
iii
solvent
methoxy
Prior art date
Application number
SK328-98A
Other languages
English (en)
Slovak (sk)
Other versions
SK32898A3 (en
Inventor
Ulf H. Dolling
Lisa F. Frey
Richard D. Tillyer
David M. Tschaen
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9602925.1A external-priority patent/GB9602925D0/en
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of SK32898A3 publication Critical patent/SK32898A3/sk
Publication of SK282779B6 publication Critical patent/SK282779B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/54Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SK328-98A 1995-09-15 1996-09-11 Spôsob prípravy alfa-chlór alebo alfa-fluórketónu SK282779B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US382395P 1995-09-15 1995-09-15
GBGB9602925.1A GB9602925D0 (en) 1996-02-13 1996-02-13 Synthesis of a-chloro or fluoro ketones
PCT/US1996/014565 WO1997010195A1 (en) 1995-09-15 1996-09-11 SYNTHESIS OF α-CHLORO OR FLUORO KETONES

Publications (2)

Publication Number Publication Date
SK32898A3 SK32898A3 (en) 1998-11-04
SK282779B6 true SK282779B6 (sk) 2002-12-03

Family

ID=26308680

Family Applications (1)

Application Number Title Priority Date Filing Date
SK328-98A SK282779B6 (sk) 1995-09-15 1996-09-11 Spôsob prípravy alfa-chlór alebo alfa-fluórketónu

Country Status (18)

Country Link
EP (1) EP0851850B1 (de)
CN (1) CN1101374C (de)
AR (1) AR003509A1 (de)
AT (1) ATE210624T1 (de)
AU (1) AU6973896A (de)
BR (1) BR9610272A (de)
CZ (1) CZ290202B6 (de)
DE (1) DE69617969T2 (de)
DK (1) DK0851850T3 (de)
EA (1) EA001935B1 (de)
ES (1) ES2167600T3 (de)
HK (1) HK1010189A1 (de)
PT (1) PT851850E (de)
RO (1) RO120706B1 (de)
SK (1) SK282779B6 (de)
TW (1) TW338032B (de)
UA (1) UA57001C2 (de)
WO (1) WO1997010195A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE280167T1 (de) 1999-07-23 2004-11-15 Pfizer Prod Inc Zwischenprodukte und ein verfahren zur herstellung von beta3-adrenergischer rezeptor- agoniste
CN107746388B (zh) * 2017-11-23 2021-01-01 江苏恒盛药业有限公司 一种伏立康唑中间体的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1596278A (en) * 1976-11-30 1981-08-26 Glaxo Operations Ltd 7-(-oxyimino-acetamino)cephalosporin derivatives

Also Published As

Publication number Publication date
EA001935B1 (ru) 2001-10-22
EP0851850A1 (de) 1998-07-08
BR9610272A (pt) 1999-07-06
CN1195337A (zh) 1998-10-07
HK1010189A1 (en) 1999-06-17
DE69617969D1 (de) 2002-01-24
AU6973896A (en) 1997-04-01
PT851850E (pt) 2002-05-31
EA199800297A1 (ru) 1998-08-27
SK32898A3 (en) 1998-11-04
CN1101374C (zh) 2003-02-12
WO1997010195A1 (en) 1997-03-20
UA57001C2 (uk) 2003-06-16
ES2167600T3 (es) 2002-05-16
DK0851850T3 (da) 2002-03-25
ATE210624T1 (de) 2001-12-15
TW338032B (en) 1998-08-11
RO120706B1 (ro) 2006-06-30
AR003509A1 (es) 1998-08-05
EP0851850B1 (de) 2001-12-12
CZ290202B6 (cs) 2002-06-12
DE69617969T2 (de) 2002-06-27
CZ76998A3 (cs) 1998-07-15

Similar Documents

Publication Publication Date Title
EP0553213B1 (de) Verfahren zur herstellung von (4r-cis)-1,1-dimethylethyl-6-cyanmethyl-2,2-dimethyl-1,3-dioxan-4-acetat
WO2012009818A1 (en) Protected aldehydes for use as intermediates in chemical syntheses, and processes for their preparation
WO2006080555A1 (ja) (z)-1-フェニル-1-(n,n-ジエチルアミノカルボニル)-2-フタルイミドメチルシクロプロパンの製造方法
Tang et al. Polymer-supported selenium-induced electrophilic cyclization: solid-phase synthesis of poly-substituted dihydrofurans and tetrahydrofurans
JP3393891B2 (ja) イミダゾール類の製造方法
SK282779B6 (sk) Spôsob prípravy alfa-chlór alebo alfa-fluórketónu
US5786515A (en) Synthesis of α-chloro or fluoro ketones
JP3937489B2 (ja) プロパルギルアミン化合物の製造方法
McCombie et al. New reactions of hydrazides. Part 1: Directed ortho-and lateral metalation of aromatic carbocyclic and heterocyclic systems
JPH0794420B2 (ja) 置換フェノキシアセトアルデヒドオキシム類の製造方法
JP4437093B2 (ja) 3−[2−(3,4−ジメトキシ−ベンゾイル)−4,5−ジメトキシ−フェニル]−ペンタン−2−オンの製法
JPH11349583A (ja) キナ酸誘導体の製造方法
JP2801647B2 (ja) 6―フルオロクロモン―2―カルボン酸誘導体の製造法
KR100195888B1 (ko) 디엘-3-메칠-시크로펜타데칸-1-온의 제조방법
Chambers et al. An improved synthesis of 5-fluorothiophene-2-carboxylic acid
JPH03181459A (ja) 軟体動物駆除剤の2,4,5―トリブロモピロール―3―カーボニトリル化合物の製造法
JP3365764B2 (ja) シタロプラムの製造方法
EP2011792A1 (de) 2-alkenyl-3-aminothiophenderivat und verfahren zu dessen herstellung
Khan The Claisen rearrangement of 2-phenylsulfinyl-2-propenyl phenyl ethers–A new route to functionalized phenols and 2-methylbenzofurans
JP3047582B2 (ja) トレオ−4−アルコキシ−5−(アリールヒドロキシメチル)−2(5h)−フラノンの製造方法
Yadav et al. Copper (II) tetrafluoroborate as mild and versatile catalyst for the rapid synthesis of β-acetamido ketones and ketoesters via a three component reaction.
CN113683550A (zh) 一种n-(氰基(2-氰基取代苯基)甲基)取代的三级胺的合成方法
US4451658A (en) Process for producing substituted pyrroles
Moranta et al. Oxidation on the Side Chain in 1, 2-Dialkyl-3-nitropyrroles and 3-Alkylaminosulfonyl-1, 2-dialkylpyrroles
CN115594632A (zh) 一种由芳醛与酰胺制备n-端烯基酰胺的方法