TW338032B - Synthesis of alpha-coloro or fluoro ketones - Google Patents

Synthesis of alpha-coloro or fluoro ketones

Info

Publication number
TW338032B
TW338032B TW085111202A TW85111202A TW338032B TW 338032 B TW338032 B TW 338032B TW 085111202 A TW085111202 A TW 085111202A TW 85111202 A TW85111202 A TW 85111202A TW 338032 B TW338032 B TW 338032B
Authority
TW
Taiwan
Prior art keywords
formula
synthesis
alkyl
reaction
coloro
Prior art date
Application number
TW085111202A
Other languages
English (en)
Inventor
H Dolling Ulf
F Frey Lisa
D Tillyer Richard
M Tschaen David
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9602925.1A external-priority patent/GB9602925D0/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of TW338032B publication Critical patent/TW338032B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/54Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TW085111202A 1995-09-15 1996-09-13 Synthesis of alpha-coloro or fluoro ketones TW338032B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US382395P 1995-09-15 1995-09-15
GBGB9602925.1A GB9602925D0 (en) 1996-02-13 1996-02-13 Synthesis of a-chloro or fluoro ketones

Publications (1)

Publication Number Publication Date
TW338032B true TW338032B (en) 1998-08-11

Family

ID=26308680

Family Applications (1)

Application Number Title Priority Date Filing Date
TW085111202A TW338032B (en) 1995-09-15 1996-09-13 Synthesis of alpha-coloro or fluoro ketones

Country Status (18)

Country Link
EP (1) EP0851850B1 (zh)
CN (1) CN1101374C (zh)
AR (1) AR003509A1 (zh)
AT (1) ATE210624T1 (zh)
AU (1) AU6973896A (zh)
BR (1) BR9610272A (zh)
CZ (1) CZ290202B6 (zh)
DE (1) DE69617969T2 (zh)
DK (1) DK0851850T3 (zh)
EA (1) EA001935B1 (zh)
ES (1) ES2167600T3 (zh)
HK (1) HK1010189A1 (zh)
PT (1) PT851850E (zh)
RO (1) RO120706B1 (zh)
SK (1) SK282779B6 (zh)
TW (1) TW338032B (zh)
UA (1) UA57001C2 (zh)
WO (1) WO1997010195A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE280167T1 (de) 1999-07-23 2004-11-15 Pfizer Prod Inc Zwischenprodukte und ein verfahren zur herstellung von beta3-adrenergischer rezeptor- agoniste
CN107746388B (zh) * 2017-11-23 2021-01-01 江苏恒盛药业有限公司 一种伏立康唑中间体的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1596278A (en) * 1976-11-30 1981-08-26 Glaxo Operations Ltd 7-(-oxyimino-acetamino)cephalosporin derivatives

Also Published As

Publication number Publication date
EA001935B1 (ru) 2001-10-22
EP0851850A1 (en) 1998-07-08
BR9610272A (pt) 1999-07-06
CN1195337A (zh) 1998-10-07
HK1010189A1 (en) 1999-06-17
DE69617969D1 (de) 2002-01-24
AU6973896A (en) 1997-04-01
PT851850E (pt) 2002-05-31
EA199800297A1 (ru) 1998-08-27
SK32898A3 (en) 1998-11-04
SK282779B6 (sk) 2002-12-03
CN1101374C (zh) 2003-02-12
WO1997010195A1 (en) 1997-03-20
UA57001C2 (uk) 2003-06-16
ES2167600T3 (es) 2002-05-16
DK0851850T3 (da) 2002-03-25
ATE210624T1 (de) 2001-12-15
RO120706B1 (ro) 2006-06-30
AR003509A1 (es) 1998-08-05
EP0851850B1 (en) 2001-12-12
CZ290202B6 (cs) 2002-06-12
DE69617969T2 (de) 2002-06-27
CZ76998A3 (cs) 1998-07-15

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees