SK282736B6 - Spôsob prípravy amlodipín benzénsulfonátu - Google Patents

Spôsob prípravy amlodipín benzénsulfonátu Download PDF

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Publication number
SK282736B6
SK282736B6 SK1698-99A SK169899A SK282736B6 SK 282736 B6 SK282736 B6 SK 282736B6 SK 169899 A SK169899 A SK 169899A SK 282736 B6 SK282736 B6 SK 282736B6
Authority
SK
Slovakia
Prior art keywords
amlodipine
benzenesulfonate
water
preparation
mixture
Prior art date
Application number
SK1698-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK169899A3 (en
Inventor
Marek Wlostowski
Maciej Wieczorek
Original Assignee
Adamed Sp. Z O.O.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20071938&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK282736(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Adamed Sp. Z O.O. filed Critical Adamed Sp. Z O.O.
Publication of SK169899A3 publication Critical patent/SK169899A3/sk
Publication of SK282736B6 publication Critical patent/SK282736B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SK1698-99A 1998-04-09 1999-04-08 Spôsob prípravy amlodipín benzénsulfonátu SK282736B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PL98325757A PL189666B1 (pl) 1998-04-09 1998-04-09 Sposób otrzymywania benzenosulfonianu amlodypiny
PCT/PL1999/000011 WO1999052873A1 (en) 1998-04-09 1999-04-08 A process for the preparation of amlodipine benzenesulphonate

Publications (2)

Publication Number Publication Date
SK169899A3 SK169899A3 (en) 2000-06-12
SK282736B6 true SK282736B6 (sk) 2002-11-06

Family

ID=20071938

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1698-99A SK282736B6 (sk) 1998-04-09 1999-04-08 Spôsob prípravy amlodipín benzénsulfonátu

Country Status (15)

Country Link
EP (1) EP0993447B1 (pt)
KR (1) KR100323244B1 (pt)
CN (1) CN1122023C (pt)
AT (1) ATE302187T1 (pt)
AU (1) AU3061399A (pt)
CZ (1) CZ295311B6 (pt)
DE (1) DE69926704D1 (pt)
ES (1) ES2245823T3 (pt)
HU (1) HUP0003300A3 (pt)
PL (1) PL189666B1 (pt)
PT (1) PT993447E (pt)
RU (1) RU2177000C2 (pt)
SK (1) SK282736B6 (pt)
UA (1) UA57091C2 (pt)
WO (1) WO1999052873A1 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03005882A (es) 2000-12-29 2005-04-19 Pfizer Ltd Derivado amida de amlodipina.
BR0116557A (pt) * 2000-12-29 2003-10-28 Pfizer Ltd Processo, processo para fabricação de um sal de maleato de amlodipina substancialmente livre de aspartato de amlodipina, processo para purificação, maleato de amlodipina, composição farmacêutica para tratar ou prevenir angina ou hipertenção, método para tratar hipertenção, angina ou ataque cardìaco, benzeno sulfonato de amlodipina, hidrocloreto de amlodipina e uso de maleato de amlodipina substancialmente livre de aspartato de amlodipina
GB2372036B (en) 2000-12-29 2004-05-19 Bioorg Bv Aspartate derivative of amlodipine
AT5874U1 (de) 2000-12-29 2003-01-27 Bioorg Bv Pharmazeutische zubereitungen enthaltend amlodipinmaleat
BR0116554A (pt) 2000-12-29 2004-02-03 Pfizer Ltd Composto, composição farmacêutica para o tratamento da angina ou hipertensão, processo, processo para o tratamento ou prevenção da angina ou hipertensão, composição do ingrediente farmaceuticamente ativo e composição farmacêutica para o tratamento ou prevenção da angina ou hipertensão
KR20030066782A (ko) * 2000-12-29 2003-08-09 화이자 리미티드 암로디핀 말레에이트를 제조하는 방법
CA2433284A1 (en) 2000-12-29 2002-07-11 Pfizer Limited Reference standards and processes for determining the purity or stability of amlodipine maleate
WO2002053539A1 (en) 2000-12-29 2002-07-11 Pfizer Limited Amlodipine hemimaleate
US7335380B2 (en) 2000-12-29 2008-02-26 Synthon Ip Inc. Amlodipine free base
CA2433181C (en) 2000-12-29 2005-11-22 Pfizer Limited Amlodipine hemifumarate
US6653481B2 (en) 2000-12-29 2003-11-25 Synthon Bv Process for making amlodipine
ATE356806T1 (de) * 2001-01-09 2007-04-15 Siegfried Generics Int Ag Salze von amlodipin-mesylat
ATE454890T1 (de) * 2001-07-06 2010-01-15 Lek Pharmaceuticals Verfahren zur herstellung hochreines amlodipinbenzolsulfonat
US6680334B2 (en) 2001-08-28 2004-01-20 Pfizer Inc Crystalline material
US6828339B2 (en) * 2001-11-21 2004-12-07 Synthon Bv Amlodipine salt forms and processes for preparing them
KR100496436B1 (ko) 2002-07-30 2005-06-20 씨제이 주식회사 암로디핀의 유기산염
KR100462304B1 (ko) 2002-07-30 2004-12-17 씨제이 주식회사 암로디핀의 유기산염
KR100538641B1 (ko) 2002-07-30 2005-12-22 씨제이 주식회사 암로디핀의 유기산염
KR100467669B1 (ko) 2002-08-21 2005-01-24 씨제이 주식회사 암로디핀의 유기산염
US6784297B2 (en) 2002-09-04 2004-08-31 Kopran Limited Process for the preparation of anti-ischemic and anti-hypertensive drug amlodipine besylate
WO2004026834A1 (en) 2002-09-19 2004-04-01 Cj Corporation Crystalline organic acid salt of amlodipine
US20060035940A1 (en) * 2004-03-16 2006-02-16 Sepracor Inc. (S)-Amlodipine malate
CN100391946C (zh) * 2006-05-26 2008-06-04 苏州东瑞制药有限公司 一种苯磺酸氨氯地平的制备方法
PL236001B1 (pl) 2012-12-21 2020-11-30 Adamed Spolka Z Ograniczona Odpowiedzialnoscia Złożona kompozycja farmaceutyczna zawierająca kandesartan cyleksetylu oraz amlodypinę, sposób jej wytwarzania oraz jednostkowa postać dawkowania zawierająca tę kompozycję
CN103044314A (zh) * 2013-01-06 2013-04-17 先声药业有限公司 马来酸氨氯地平的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8608335D0 (en) * 1986-04-04 1986-05-08 Pfizer Ltd Pharmaceutically acceptable salts

Also Published As

Publication number Publication date
EP0993447A1 (en) 2000-04-19
KR20010013297A (ko) 2001-02-26
CN1263525A (zh) 2000-08-16
KR100323244B1 (ko) 2002-02-19
SK169899A3 (en) 2000-06-12
EP0993447B1 (en) 2005-08-17
CN1122023C (zh) 2003-09-24
DE69926704D1 (de) 2005-09-22
CZ466999A3 (cs) 2000-04-12
PL189666B1 (pl) 2005-09-30
UA57091C2 (uk) 2003-06-16
RU2177000C2 (ru) 2001-12-20
WO1999052873A1 (en) 1999-10-21
ATE302187T1 (de) 2005-09-15
AU3061399A (en) 1999-11-01
CZ295311B6 (cs) 2005-07-13
HUP0003300A3 (en) 2002-11-28
PL325757A1 (en) 1999-10-11
PT993447E (pt) 2005-10-31
HUP0003300A2 (en) 2001-03-28
ES2245823T3 (es) 2006-01-16

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20100408