HUP0003300A3 - Process for the preparation of amlodipine benzenesulphonate - Google Patents
Process for the preparation of amlodipine benzenesulphonateInfo
- Publication number
- HUP0003300A3 HUP0003300A3 HU0003300A HUP0003300A HUP0003300A3 HU P0003300 A3 HUP0003300 A3 HU P0003300A3 HU 0003300 A HU0003300 A HU 0003300A HU P0003300 A HUP0003300 A HU P0003300A HU P0003300 A3 HUP0003300 A3 HU P0003300A3
- Authority
- HU
- Hungary
- Prior art keywords
- preparation
- amlodipine benzenesulphonate
- benzenesulphonate
- amlodipine
- Prior art date
Links
- ZPBWCRDSRKPIDG-UHFFFAOYSA-N amlodipine benzenesulfonate Chemical compound OS(=O)(=O)C1=CC=CC=C1.CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1Cl ZPBWCRDSRKPIDG-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL98325757A PL189666B1 (pl) | 1998-04-09 | 1998-04-09 | Sposób otrzymywania benzenosulfonianu amlodypiny |
PCT/PL1999/000011 WO1999052873A1 (en) | 1998-04-09 | 1999-04-08 | A process for the preparation of amlodipine benzenesulphonate |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0003300A2 HUP0003300A2 (en) | 2001-03-28 |
HUP0003300A3 true HUP0003300A3 (en) | 2002-11-28 |
Family
ID=20071938
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0003300A HUP0003300A3 (en) | 1998-04-09 | 1999-04-08 | Process for the preparation of amlodipine benzenesulphonate |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0993447B1 (hu) |
KR (1) | KR100323244B1 (hu) |
CN (1) | CN1122023C (hu) |
AT (1) | ATE302187T1 (hu) |
AU (1) | AU3061399A (hu) |
CZ (1) | CZ295311B6 (hu) |
DE (1) | DE69926704D1 (hu) |
ES (1) | ES2245823T3 (hu) |
HU (1) | HUP0003300A3 (hu) |
PL (1) | PL189666B1 (hu) |
PT (1) | PT993447E (hu) |
RU (1) | RU2177000C2 (hu) |
SK (1) | SK282736B6 (hu) |
UA (1) | UA57091C2 (hu) |
WO (1) | WO1999052873A1 (hu) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2433193C (en) | 2000-12-29 | 2006-01-31 | Pfizer Limited | Amide derivative of amlodipine |
WO2002054062A2 (en) | 2000-12-29 | 2002-07-11 | Pfizer Limited | Reference standards and processes for determining the purity or stability of amlodipine maleate |
MXPA03005882A (es) | 2000-12-29 | 2005-04-19 | Pfizer Ltd | Derivado amida de amlodipina. |
US6653481B2 (en) | 2000-12-29 | 2003-11-25 | Synthon Bv | Process for making amlodipine |
GEP20063946B (en) * | 2000-12-29 | 2006-10-25 | Pfizer Ltd | Process for making amlodipine maleate |
US7335380B2 (en) | 2000-12-29 | 2008-02-26 | Synthon Ip Inc. | Amlodipine free base |
CA2433190C (en) | 2000-12-29 | 2005-11-15 | Pfizer Limited | Amlodipine hemimaleate |
CA2433181C (en) | 2000-12-29 | 2005-11-22 | Pfizer Limited | Amlodipine hemifumarate |
EP1309558A1 (en) | 2000-12-29 | 2003-05-14 | Synthon Licensing, Ltd. | Aspartate derivative of amlodipine as calcium channel antagonist |
AT5874U1 (de) | 2000-12-29 | 2003-01-27 | Bioorg Bv | Pharmazeutische zubereitungen enthaltend amlodipinmaleat |
PL362660A1 (en) | 2000-12-29 | 2004-11-02 | Pfizer Limited | Process for making amlodipine maleate |
ATE356806T1 (de) * | 2001-01-09 | 2007-04-15 | Siegfried Generics Int Ag | Salze von amlodipin-mesylat |
ATE454890T1 (de) * | 2001-07-06 | 2010-01-15 | Lek Pharmaceuticals | Verfahren zur herstellung hochreines amlodipinbenzolsulfonat |
US6680334B2 (en) | 2001-08-28 | 2004-01-20 | Pfizer Inc | Crystalline material |
US6828339B2 (en) * | 2001-11-21 | 2004-12-07 | Synthon Bv | Amlodipine salt forms and processes for preparing them |
KR100496436B1 (ko) | 2002-07-30 | 2005-06-20 | 씨제이 주식회사 | 암로디핀의 유기산염 |
KR100538641B1 (ko) | 2002-07-30 | 2005-12-22 | 씨제이 주식회사 | 암로디핀의 유기산염 |
KR100462304B1 (ko) | 2002-07-30 | 2004-12-17 | 씨제이 주식회사 | 암로디핀의 유기산염 |
KR100467669B1 (ko) | 2002-08-21 | 2005-01-24 | 씨제이 주식회사 | 암로디핀의 유기산염 |
US6784297B2 (en) | 2002-09-04 | 2004-08-31 | Kopran Limited | Process for the preparation of anti-ischemic and anti-hypertensive drug amlodipine besylate |
WO2004026834A1 (en) * | 2002-09-19 | 2004-04-01 | Cj Corporation | Crystalline organic acid salt of amlodipine |
US20060030602A1 (en) * | 2004-03-16 | 2006-02-09 | Sepracor Inc. | (S)-amlodipine malate |
CN100391946C (zh) * | 2006-05-26 | 2008-06-04 | 苏州东瑞制药有限公司 | 一种苯磺酸氨氯地平的制备方法 |
PL236001B1 (pl) | 2012-12-21 | 2020-11-30 | Adamed Spolka Z Ograniczona Odpowiedzialnoscia | Złożona kompozycja farmaceutyczna zawierająca kandesartan cyleksetylu oraz amlodypinę, sposób jej wytwarzania oraz jednostkowa postać dawkowania zawierająca tę kompozycję |
CN103044314A (zh) * | 2013-01-06 | 2013-04-17 | 先声药业有限公司 | 马来酸氨氯地平的制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8608335D0 (en) * | 1986-04-04 | 1986-05-08 | Pfizer Ltd | Pharmaceutically acceptable salts |
-
1998
- 1998-04-09 PL PL98325757A patent/PL189666B1/pl unknown
-
1999
- 1999-04-08 AU AU30613/99A patent/AU3061399A/en not_active Abandoned
- 1999-04-08 SK SK1698-99A patent/SK282736B6/sk not_active IP Right Cessation
- 1999-04-08 AT AT99912189T patent/ATE302187T1/de not_active IP Right Cessation
- 1999-04-08 CN CN99800509A patent/CN1122023C/zh not_active Expired - Fee Related
- 1999-04-08 HU HU0003300A patent/HUP0003300A3/hu unknown
- 1999-04-08 RU RU2000100282/04A patent/RU2177000C2/ru not_active IP Right Cessation
- 1999-04-08 PT PT99912189T patent/PT993447E/pt unknown
- 1999-04-08 WO PCT/PL1999/000011 patent/WO1999052873A1/en active IP Right Grant
- 1999-04-08 EP EP99912189A patent/EP0993447B1/en not_active Expired - Lifetime
- 1999-04-08 ES ES99912189T patent/ES2245823T3/es not_active Expired - Lifetime
- 1999-04-08 CZ CZ19994669A patent/CZ295311B6/cs not_active IP Right Cessation
- 1999-04-08 KR KR1019997011291A patent/KR100323244B1/ko not_active IP Right Cessation
- 1999-04-08 DE DE69926704T patent/DE69926704D1/de not_active Expired - Lifetime
- 1999-08-04 UA UA2000010042A patent/UA57091C2/uk unknown
Also Published As
Publication number | Publication date |
---|---|
DE69926704D1 (de) | 2005-09-22 |
SK282736B6 (sk) | 2002-11-06 |
CZ466999A3 (cs) | 2000-04-12 |
CZ295311B6 (cs) | 2005-07-13 |
AU3061399A (en) | 1999-11-01 |
UA57091C2 (uk) | 2003-06-16 |
ES2245823T3 (es) | 2006-01-16 |
WO1999052873A1 (en) | 1999-10-21 |
EP0993447B1 (en) | 2005-08-17 |
EP0993447A1 (en) | 2000-04-19 |
HUP0003300A2 (en) | 2001-03-28 |
CN1122023C (zh) | 2003-09-24 |
PL325757A1 (en) | 1999-10-11 |
SK169899A3 (en) | 2000-06-12 |
PL189666B1 (pl) | 2005-09-30 |
PT993447E (pt) | 2005-10-31 |
KR20010013297A (ko) | 2001-02-26 |
ATE302187T1 (de) | 2005-09-15 |
RU2177000C2 (ru) | 2001-12-20 |
CN1263525A (zh) | 2000-08-16 |
KR100323244B1 (ko) | 2002-02-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |