GEP20063946B - Process for making amlodipine maleate - Google Patents
Process for making amlodipine maleateInfo
- Publication number
- GEP20063946B GEP20063946B GE5245A GEAP2001005245A GEP20063946B GE P20063946 B GEP20063946 B GE P20063946B GE 5245 A GE5245 A GE 5245A GE AP2001005245 A GEAP2001005245 A GE AP2001005245A GE P20063946 B GEP20063946 B GE P20063946B
- Authority
- GE
- Georgia
- Prior art keywords
- amlodipine maleate
- amlodipine
- making
- making amlodipine
- maleate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
A process for making amlodipine maleate substantially free from amlodipine aspartate comprises reacting amlodipine or an acid addition salt thereof with maleic acid. Method for purifying amlodipine maleate and pharmaceutical composition on its base.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25861200P | 2000-12-29 | 2000-12-29 | |
US80934301A | 2001-03-16 | 2001-03-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
GEP20063946B true GEP20063946B (en) | 2006-10-25 |
Family
ID=41639550
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GE5245A GEP20063946B (en) | 2000-12-29 | 2001-08-15 | Process for making amlodipine maleate |
Country Status (4)
Country | Link |
---|---|
KR (1) | KR20030066782A (en) |
EA (1) | EA008141B1 (en) |
GE (1) | GEP20063946B (en) |
OA (1) | OA13133A (en) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK161312C (en) * | 1982-03-11 | 1991-12-09 | Pfizer | CHANGES FOR THE PREPARATION FOR THE PREPARATION OF 2-Amino-CO-Methyl-4-Methyl-4-Methyl-4-Methyl-4-Methyl-4-Methyl-4-Methyl-2-D-Hydroxy |
PL189666B1 (en) * | 1998-04-09 | 2005-09-30 | Adamed Sp Z Oo | Method of obtaining amlopidine benzenosulphonate |
-
2001
- 2001-08-15 GE GE5245A patent/GEP20063946B/en unknown
- 2001-08-15 EA EA200300741A patent/EA008141B1/en unknown
- 2001-08-15 KR KR10-2003-7008835A patent/KR20030066782A/en not_active Application Discontinuation
- 2001-08-15 OA OA1200300166A patent/OA13133A/en unknown
Also Published As
Publication number | Publication date |
---|---|
OA13133A (en) | 2006-12-13 |
KR20030066782A (en) | 2003-08-09 |
EA008141B1 (en) | 2007-04-27 |
EA200300741A1 (en) | 2003-10-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MXPA03005885A (en) | Process for making amlodipine maleate. | |
HK1060572A1 (en) | Preparation process of pyrrole-3-carboxylic acid phenylamide derivatices. | |
EP1449918A4 (en) | Process for producing l-amino acid using escherichia | |
HUP0103445A2 (en) | Method for producing basic amino acid | |
HK1067129A1 (en) | A process for the preparation of perindopril, its analgous compounds and salts thereof using 2,5-dioxo-oxazolidine intermediate compounds | |
HUP0001285A3 (en) | Pyrrolidine derivatives as protease inhibitors, process for producing them and pharmaceutical compositions containing them | |
EP1295873A4 (en) | Processes for producing racemic piperidine derivative and for producing optically active piperidine derivative | |
HK1056868A1 (en) | Novel dicarboxylic acid derivatives. | |
HK1057363A1 (en) | Ccr5 antagonists useful for treating aids. | |
CA2372986A1 (en) | Process for the condensation of polyamides | |
AU5707000A (en) | Process for producing l-amino acid | |
IL143993A0 (en) | An incineration process using high oxygen concentrations | |
WO2001058875A3 (en) | Substituted 1,2,3,4- tetrahydroquinoline-2-carboxylic acid derivatives | |
GEP20063946B (en) | Process for making amlodipine maleate | |
HUP0105456A2 (en) | Aspartate derivative of amlodipine, process for producing it and pharmaceutical composition containing it | |
IL145723A0 (en) | Process for producing an amide compound | |
MXPA03009091A (en) | Novel n-p-propargyloxyphenethyl-thioacetic acid amides. | |
AU5707100A (en) | Process for producing l-amino acid | |
SG96650A1 (en) | Electronic account settlement apparatus, electronic settlement method, and computer-program | |
AU2002226308A1 (en) | Method for producing dnda | |
HK1052535A1 (en) | Process for producing l-amino acid via fermentation method | |
ZA200101340B (en) | 6-amino or 6-hydrazino-sulphonyl-3-quinolinylphosphonic acid compounds, a process for their preparation and pharmaceutical composition containing them. | |
AU2002223617A1 (en) | Novel neurokinin antagonists, method for the production thereof and pharmaceutical compositions containing said compounds | |
IL150638A0 (en) | Pseudopolymorph of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8 [4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-one | |
AU2002219129A1 (en) | Enhancer for 2, 4-dichlorophenoxyacetic acid and methylchlorophenoxyacetic acid |