SK282047B6 - Taxoidy, spôsoby ich prípravy a farmaceutická kompozícia obsahujúca tieto taxoidy - Google Patents

Taxoidy, spôsoby ich prípravy a farmaceutická kompozícia obsahujúca tieto taxoidy Download PDF

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Publication number
SK282047B6
SK282047B6 SK1333-97A SK133397A SK282047B6 SK 282047 B6 SK282047 B6 SK 282047B6 SK 133397 A SK133397 A SK 133397A SK 282047 B6 SK282047 B6 SK 282047B6
Authority
SK
Slovakia
Prior art keywords
group
carbon atoms
formula
alkyl
phenyl
Prior art date
Application number
SK1333-97A
Other languages
English (en)
Slovak (sk)
Other versions
SK133397A3 (en
Inventor
Herv Bouchard
Jean-Dominique Bourzat
Alain Commeron
Original Assignee
Rhone-Poulenc Rorer S. A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone-Poulenc Rorer S. A. filed Critical Rhone-Poulenc Rorer S. A.
Publication of SK133397A3 publication Critical patent/SK133397A3/sk
Publication of SK282047B6 publication Critical patent/SK282047B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1333-97A 1995-04-03 1996-04-01 Taxoidy, spôsoby ich prípravy a farmaceutická kompozícia obsahujúca tieto taxoidy SK282047B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9503868A FR2732342B1 (fr) 1995-04-03 1995-04-03 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR1996/000487 WO1996031493A1 (fr) 1995-04-03 1996-04-01 Nouveaux taxoïdes, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
SK133397A3 SK133397A3 (en) 1998-02-04
SK282047B6 true SK282047B6 (sk) 2001-10-08

Family

ID=9477663

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1333-97A SK282047B6 (sk) 1995-04-03 1996-04-01 Taxoidy, spôsoby ich prípravy a farmaceutická kompozícia obsahujúca tieto taxoidy

Country Status (32)

Country Link
US (1) US5959125A (el)
EP (1) EP0821680B1 (el)
JP (1) JPH11504004A (el)
KR (1) KR19980703520A (el)
CN (1) CN1073106C (el)
AP (1) AP784A (el)
AR (1) AR002730A1 (el)
AT (1) ATE195940T1 (el)
AU (1) AU703918B2 (el)
BG (1) BG62964B1 (el)
BR (1) BR9604799A (el)
CA (1) CA2214322C (el)
CZ (1) CZ287430B6 (el)
DE (1) DE69610085T2 (el)
DK (1) DK0821680T3 (el)
EA (1) EA000726B1 (el)
ES (1) ES2151155T3 (el)
FR (1) FR2732342B1 (el)
GE (1) GEP19991872B (el)
GR (1) GR3034203T3 (el)
HU (1) HUP9802042A3 (el)
IL (1) IL117760A (el)
MX (1) MX9707427A (el)
NO (1) NO974563L (el)
NZ (1) NZ305898A (el)
PL (1) PL322581A1 (el)
PT (1) PT821680E (el)
RO (1) RO115879B1 (el)
SK (1) SK282047B6 (el)
TW (1) TW347389B (el)
WO (1) WO1996031493A1 (el)
ZA (1) ZA962633B (el)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
FR2764118B1 (fr) * 1997-05-30 2000-08-04 Thomson Csf Transistor bipolaire stabilise avec elements isolants electriques
US6156789A (en) * 1998-03-17 2000-12-05 Rhone-Poulenc Rorer S.A. Method for treating abnormal cell proliferation in the brain
JP2002543127A (ja) * 1999-05-03 2002-12-17 アベンテイス・フアルマ・ソシエテ・アノニム 脳内の異常な細胞の増殖を処置する方法
CN1362959A (zh) * 2000-02-02 2002-08-07 佛罗里达州立大学研究基金有限公司 C10氨基甲酰氧基取代的紫衫烷抗肿瘤剂
US6649632B2 (en) * 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
HUP0200759A3 (en) 2000-02-02 2002-10-28 Univ Florida State Res Found C10 carbonate substituted taxanes as antitumor agents and pharmaceutical compositions containing them and their use
JP2004339475A (ja) * 2003-02-03 2004-12-02 Merck Patent Gmbh フッ化物、オキシフッ化物、フルオロ硫化物および/またはオキシフルオロ硫化物に基づく真珠光沢顔料
WO2004103344A1 (en) * 2003-05-20 2004-12-02 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
HN2005000054A (es) * 2004-02-13 2009-02-18 Florida State University Foundation Inc Taxanos sustituidos con esteres de ciclopentilo en c10
WO2006088767A2 (en) * 2005-02-14 2006-08-24 Florida State University Research Foundation, Inc. C10 cyclopropyl ester substituted taxane compositions
JP2011517455A (ja) * 2008-03-31 2011-06-09 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド C(10)エチルエステルおよびc(10)シクロプロピルエステル置換タキサン

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ248017A (en) * 1992-07-01 1994-12-22 Bristol Myers Squibb Co 7-fluoro-taxol derivatives, precursors and pharmaceutical compositions thereof
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
IL107950A (en) * 1992-12-15 2001-04-30 Upjohn Co b 7, b 8 - Matano - Taxols, their preparation and pharmaceutical preparations against malignant tumors containing them

Also Published As

Publication number Publication date
IL117760A0 (en) 1996-08-04
PT821680E (pt) 2000-12-29
EP0821680A1 (fr) 1998-02-04
ZA962633B (en) 1996-10-07
US5959125A (en) 1999-09-28
HUP9802042A3 (en) 2001-02-28
IL117760A (en) 2001-11-25
ES2151155T3 (es) 2000-12-16
BG101940A (en) 1998-11-30
TW347389B (en) 1998-12-11
KR19980703520A (ko) 1998-11-05
GR3034203T3 (en) 2000-11-30
CA2214322C (fr) 2007-01-30
CN1179777A (zh) 1998-04-22
MX9707427A (es) 1998-02-28
PL322581A1 (en) 1998-02-02
CN1073106C (zh) 2001-10-17
BG62964B1 (bg) 2000-12-29
DE69610085T2 (de) 2001-01-11
RO115879B1 (ro) 2000-07-28
BR9604799A (pt) 1999-04-06
AU703918B2 (en) 1999-04-01
NO974563L (no) 1997-11-24
FR2732342B1 (fr) 1997-04-30
WO1996031493A1 (fr) 1996-10-10
NO974563D0 (no) 1997-10-02
AR002730A1 (es) 1998-04-29
NZ305898A (en) 1998-12-23
CZ287430B6 (en) 2000-11-15
EA199700288A1 (ru) 1998-04-30
CZ310997A3 (cs) 1998-01-14
ATE195940T1 (de) 2000-09-15
JPH11504004A (ja) 1999-04-06
AP9701094A0 (en) 1997-10-31
EP0821680B1 (fr) 2000-08-30
HUP9802042A2 (hu) 2000-06-28
EA000726B1 (ru) 2000-02-28
SK133397A3 (en) 1998-02-04
AU5402896A (en) 1996-10-23
CA2214322A1 (fr) 1996-10-10
GEP19991872B (en) 1999-12-06
AP784A (en) 1999-11-22
FR2732342A1 (fr) 1996-10-04
DE69610085D1 (de) 2000-10-05
DK0821680T3 (da) 2000-11-20

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